Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo

Molecular Pharmacology

Volumn 84, Issue 5, 2013, Pages 736-750

  Straub, Isabelle ^a   Krügel, Ute ^a   Mohr, Florian ^b   Teichert, Jens ^a   Rizun, Oleksandr ^b   Konrad, Maik ^b   Oberwinkler, Johannes ^b   Schaefer, Michael ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ERIODICTYOL; FLAVANONE; FLAVANONE DERIVATIVE; GLYCOSIDE; HESPERETIN; INTRACELLULAR CALCIUM SENSING PROTEIN; ISOSAKURANETIN; LIQUIRITIGENIN; NARINGENIN; NEUROSTEROID PREGNENOLONE SULFATE; ONONETIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CELL ISOLATION; CONTROLLED STUDY; DORSAL ROOT; DRUG POTENCY; DRUG TOLERABILITY; GRAPEFRUIT; HEAT; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; ION CURRENT; MOUSE; NOCICEPTION; NONHUMAN; ONONIS SPINOSA; PRIORITY JOURNAL; RAT; RESCREENING; SENSORY NERVE CELL; THERMAL EXPOSURE; THERMAL HYPERALGESIA; THERMAL NOCICEPTION; TRIGEMINUS GANGLION;

ANIMALS; CALCIUM; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLAVANONES; FLAVONOIDS; HEK293 CELLS; HUMANS; HYPERALGESIA; MALE; MICE; MICE, INBRED C57BL; PREGNENOLONE; RATS; RATS, WISTAR; TRPM CATION CHANNELS; TRPV CATION CHANNELS;

EID: 84886001653     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.086843     Document Type: Article

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