Alterations on Na+,K+-ATPase and acetylcholinesterase activities induced by amyloid-β peptide in rat brain and GM1 ganglioside neuroprotective action

Neurochemical Research

Volumn 38, Issue 11, 2013, Pages 2342-2350

  Kreutz, Fernando ^a   Scherer, Emilene B ^a   Ferreira, Andréa G K ^a   Petry, Fernanda Dos Santos ^a   Pereira, Camila Lino ^a   Santana, Fabiana ^a   De Souza Wyse, Angela Terezinha ^a   Salbego, Christianne Gazzana ^a   Trindade, Vera Maria Treis ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

AChE; Alzheimer's disease; Amyloid ; GM1; Na+K+ ATPase; Neuroprotection

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMYLOID BETA PROTEIN[1-42]; GANGLIOSIDE GM1;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; BRAIN CORTEX; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; IN VIVO STUDY; LEARNING DISORDER; LONG TERM MEMORY; MALE; MEMORY DISORDER; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECOGNITION; SHORT TERM MEMORY; TASK PERFORMANCE;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ACETYLCHOLINESTERASE; AMYLOID BETA-PEPTIDES; ANIMALS; G(M1) GANGLIOSIDE; INJECTIONS, INTRAVENTRICULAR; MALE; MEMORY; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84885956459     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-013-1145-6     Document Type: Article

References (55)

1. Suh Y, Checler F (2002) Amyloid precursor protein, presenilins, and α-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease (review). Pharmacol Rev 54:469-525
2. Mattson MP (2004) Pathways towards and away from Alzheimer's disease. Nature 430:631-639
3. Zhang LN, Sun YJ, Pan S, Li JX, Qu YE, Li Y, Wang YL, Gao ZB (2013) Na(+),K(+)-ATPase, a potent neuroprotective modulator against Alzheimer disease. Fundam Clin Pharmacol 27(1):96-103
4. Gu QB, Zhao JX, Feib J, Sshwarz W (2004) Modulation of Na+,K+ pumping and neurotransmitter uptake by β-amyloid. Neuroscience 126:61-67
5. Pákáski M, Kálmán J (2008) Interactions between the amyloid and cholinergic mechanisms in Alzheimer's Disease. Neurochem Int 53:103-111
6. Mancuso C, Siciliano R, Barone E, Butterfield DA, Preziosi P (2011) Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before. Expert Opin Investig Drugs 20:1243-1261
7. Wyse ATS, Streck EL, Worm P, Wajner M, Ritter F, Netto CA (2000) Preconditioning prevents the inhibition of Na+,K+-ATPase activity after brain ischemia. Neurochem Res 25:971-975
8. Kurup AR, Kurup PA (2002) Membrane Na(+),K(+)-ATPase mediated cascade in bipolar mood disorder, major depressive disorder, and schizophrenia-relationship to hemispheric dominance. Int J Neurosci 112:965-982
9. Ferreira AG, Stefanello FM, Cunha AA, da Cunha MJ, Pereira TC, Bonan CD, Bogo MR, Netto CA, Wyse AT (2011) Role of antioxidants on Na(+),K (+)-ATPase activity and gene expression in cerebral cortex of hyperprolinemic rats. Metab Brain Dis 26:141-147
10. Simão F, Matté A, Matté C, Soares FM, Wyse AT, Netto CA, Salbego CG (2011) Resveratrol prevents oxidative stress and inhibition of Na(+),K(+)-ATPase activity induced by transient global cerebral ischemia in rats. J Nutr Biochem 22:921-928
11. Sasahara K, Morigaki K, Shinya K (2013) Effects of membrane interaction and agregation of amyloid b-peptide on lipid mobility and membrane domain structure. Phys Chem Chem Phys. doi: 10.1039/c3cp44517h
12. Kreutz F, Frozza RL, Breier AC, de Oliveira VA, Horn AP, Pettenuzzo LF, Netto CA, Salbego CG, Trindade VM (2011) Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action. Neurochem Int 59(5):648-655
13. Yang R, Wang Q, Min L, Sui R, Li J, Liu X (2013) Monosialoanglioside improves memory deficits and relieves oxidative stress in the hippocampus of rat model of Alzheimer's disease. Neurol Sci 34:1447-1451
14. Hadjiconstantinou M, Neff NH (1998) GM1 Ganglioside: in vivo and in vitro trophic actions on central neurotransmitter systems. J Neurochem 70:1335-1345
15. Cunha GM, Moraes RA, Moraes GA, França MC Jr, Moraes MO, Viana GS (1999) Nerve growth factor, ganglioside and vitamin E reverse glutamate cytotoxicity in hippocampal cells. Eur J Pharmacol 367:107-112
16. Rabin SJ, Bachis A, Mocchetti I (2002) Gangliosides activate trk receptors by inducing the release of neurotrophins. J Biol Chem 277:49466-49472
17. Mocchetti I (2005) Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins (review). Cell Mol Life Sci 62:2283-2294
18. Sokolova TV, Zakharova IO, Furaev VV, Rychkova MP, Avrova NF (2007) Neuroprotective effect of ganglioside GM1 on the cytotoxic action of hydrogen peroxide and amyloid beta-peptide in PC12 cells. Neurochem Res 32:1302-1313
19. Svennerholm L, Brane G, Darlsson I, Leckman A, Ramstrom I, Wikkelso C (2002) Alzheimer disease- effect of continuous intracerebroventricular treatment with GM1 ganglioside and a systematic activation programme. Dement Geriatr Cogn Disord 14:128-136
20. Streck EL, Zugno AI, Tagliari B, Franzon R, Wannmacher CM, Wajner M, Wyse AT (2001) Inhibition of rat brain Na+,K+-ATPase activity induced by homocysteine is probably mediated by oxidative stress. Neurochem Res 26:1195-1200
21. Bavaresco CS, Chiarani F, Wajner M, Netto CA, Wyse ATS (2006) Intrastriatal hypoxanthine administration affects Na+,K+-ATPase, acetylcholinesterase and catalase activities in striatum, hippocampus and cerebral cortex of rats. Int J Devl Neurosci 24:411-417
22. Khadrawy YA, Nour NA, Aboul Ezz HS (2011) Effect of oxidative stress induced by paradoxical sleep deprivation on the activities of Na+,K+-ATPase and acetylcholinesterase in the cortex and hippocampus of rat. Transl Res 157:100-107
23. Frozza RL, Bernardi A, Hoppe JB, Meneghetti AB, Matté A, Battastini AM, Pohlmann AR, Guterres SS, Salbego C (2013) Neuroprotective effects of resveratrol against Aβ administration in rats are improved by lipid-core nanocapsules. Mol Neurobiol. doi: 10.1007/s12035-013-8401-2
24. Paxinos G, Watson C (2005) The rat brain in stereotaxic coordinates, 5th edn. Elsevier Academic, San Diego
25. Matsuoka Y, Saito M, LaFrancois J, Saito M, Gaynor K, Olm V, Wang L, Casey E, Lu Y, Shiratori C, Lemere C, Duff K (2003) Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid. J Neurosci 23:29-33
26. Bevins RA, Besheer J (2006) Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'. Nat Protocols 1:1306-1311
27. Antunes M, Biala G (2012) The novel object recognition memory: neurobiology, test procedure, and its modifications. Cogn Process 13:93-110
28. Ennaceur A, Delacour J (1988) A new one-trial test for neurobiological studies of memory in rats. 1 behavioral data. Behav Brain Res 31:47-59
29. Ellman GI, Courtney KD, Andres Jr, Feather-Stone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88-95
30. Scherer EB, da Cunha AA, Kolling J, da Cunha MJ, Schmitz F, Sitta A, Lima DD, Delwing D, Vargas CR, Wyse AT (2011) Development of an animal model for chronic mild hyperhomocysteinemia and its response to oxidative damage. Int J Dev Neurosci 29:693-699
31. Chan KM, Delfert D, Junger KD (1986) A direct colorimetric assay for Ca+-stimulated ATPase activity. Anal Biochem 157:375-380
32. Scherer EB, da Cunha MJ, Matté C, Schmitz F, Netto CA, Wyse AT (2010) Methylphenidate affects memory, brain-derived neurotrophic factor immunocontent and brain acetylcholinesterase activity in the rat. Neurobiol Learn Mem 94:247-253
33. Lissi E, Pascual C, Del Castillo MD (1992) Luminol luminescence induced by 2,20-azo-bis (2-amidinopropane) thermolysis. Free Radic Res Commun 17:299-311
34. Bradford MM (1976) A rapid and sensitive method for the quantification of micrograms quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
35. Hernandez JR (1992) Na+,K+-ATPase regulation by neurotransmitters. Neurochem Int 20:1-10
36. Zhang L, Zhang Z, Guo H, Wang Y (2008) Na+/K+-ATPase-mediated signal transduction and Na+/K+-ATPase regulation. Fundam Clini Pharmacol 22:615-621
37. Mark RJ, Hensley K, Butterfield DA, Mattson MP (1995) Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death. J Neurosci 15:6239-6249
38. Chauhan NB, Lee JM, Siegel GJ (1997) Na, K-ATPase mRNA levels and plaque load in Alzheimer's disease. J Mol Neurosci 9:151-166
39. Wyse AT, Bavaresco CS, Reis EA et al (2004) Training in inhibitory avoidance causes a reduction of Na+,K+-ATPase activity in rat hippocampus. Physiol Behav 80:475-479
40. Rose EM, Koo JCP, Antflick JE, Ahmed SM, Angers S, Hampson DR (2009) Glutamate Transporter Coupling to Na, K-ATPase. J Neurosci 29:8143-8155
41. Yu SP (2003) Na+,K+-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death. Biochem Pharmacol 66:1601-1609
42. Kairane C, Roots K, Uusma T et al (2002) Regulation of the frontocortical sodium pump by Na+ in Alzheimer's disease: difference from the age-matched control but similarity to the rat model. FEBS Lett 531:241-244
43. Melo JB, Agostinho P, Oliveira CR (2003) Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide. Neurosci Res 45:117-127
44. Kar S, Slowikowski SP, Westaway D, Mount HT (2004) Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease. J Psychiatry Neurosci 29:427-441
45. Cai Z, Zhao B, Ratka A (2011) Oxidative stress and b-amyloid protein in Alzheimer's disease. Neuromolecular Med 13:223-250
46. Hieber V, Siegel GJ, Fink DJ, Beaty MW, Mata M (1991) Differential distribution of (Na, K)-ATPase alpha isoforms in the central nervous system. Cell Mol Neurobiol 11:253-262
47. Orlando P, Cocciante G, Ippolito G, Massari P, Roberti S, Tettamanti G (1979) The fate of tritium labeled GM1 ganglioside injected in mice. Pharmacol Res Commun 11:759-773
48. Ghidoni R, Fiorilli A, Trinchera M, Venerando B, Chigorno V, Tettamanti G (1989) Uptake, cell penetration and metabolic processing of exogenously administred GM1 ganglioside in rat brain. Neurochem Int 15:455-465
49. Kaida K, Ariga T, Yu RK (2009) Antiganglioside antibodies and their pathophysiological effects on Guillan-Barré syndrome and related disorders: a review. Glycobiology 19:676-702
50. Schneider JS, Gollomp SM, Sendek S, Colcher A, Cambi F, Du W (2013) A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson's disease patients. J Neurol Sci 324:140-148
51. Dhanushkodi A, McDonald MP (2011) Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration. PLoS ONE 6:e29285
52. Maysinger D, Jalsenjak V, Stolnik S, Garofalo L, Cuello AC, Jalsenjak I (1989) Microencapsulated monosialoganglioside GM1: physical properties and in vivo effects. J Microencapsul 6:35-42
53. Wells JN, Ventura RF, Eisenhauer PB, McKenna DC, Fine RE, Ullman MD (1996) Transport of GM1 and GM1 inner ester across an in vitro model of the blood-brain barrier. Neurosci Lett 217:121-124
54. Wu G, Lu ZH, Wang J, Wang Y, Xie X, Meyenhofer MF, Ledeen RW (2005) Enhanced susceptibility to kainite-induced seizures, neuronal apoptosis, and death in mice lacking gangliotetraose gangliosides: protection with LIGA20, a membrane-permeant analog of GM1. J Neurosci 25:11014-11022
55. Biraboneye AC, Madonna S, Laras Y, Krantic S, Maher P, Kraus JL (2009) Potential neuroprotective drugs in cerebral ischemia: new saturated and polyunsaturated lipids coupled to hydrophilic moieties: synthesis and biological activity. J Med Chem 52:4358-4369