Comparison of ATR-FTIR spectra of porcine vaginal and buccal mucosa with ear skin and penetration analysis of drug and vehicle components into pig ear

European Journal of Pharmaceutical Sciences

Volumn 50, Issue 5, 2013, Pages 595-600

  Schwarz, Julia C ^a   Pagitsch, Elisabeth ^a   Valenta, Claudia ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

ATR FTIR; Buccal mucosa; Liposome; Skin; Skin penetration; Vaginal mucosa

Indexed keywords

FLUFENAMIC ACID; LIPOSOME; PHOSPHATIDYLCHOLINE;

ANIMAL TISSUE; ARTICLE; CHEEK MUCOSA; COMPARATIVE STUDY; DRUG PENETRATION; EXPERIMENTAL PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIPID BILAYER; LIPOSOMAL DELIVERY; MEMBRANE PERMEABILITY; MICROEMULSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; REPRODUCIBILITY; SKIN PENETRATION; VAGINA MUCOSA; VIBRATION;

ATR-FTIR; BUCCAL MUCOSA; LIPOSOME; SKIN; SKIN PENETRATION; VAGINAL MUCOSA;

ANIMALS; EAR; FEMALE; FLUFENAMIC ACID; LIPOSOMES; MOUTH MUCOSA; MUCOUS MEMBRANE; PERMEABILITY; SKIN; SKIN ABSORPTION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SWINE; VAGINA;

EID: 84885952262     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.12.020     Document Type: Article

References (33)

1. K. Babita, V. Kumar, V. Rana, S. Jain, and A.K. Tiwary Thermotropic and spectroscopic behavior of skin: relationship with percutaneous penetration enhancement Curr. Drug Del. 3 2006 95 113
2. M. Boncheva, F. Damien, and V. Normand Molecular organization of the lipid matrix in intact stratum corneum using ATR-FTIR spectroscopy Biochim. Biophys. Acta 1778 2008 1344 1355
3. J.A. Bouwstra, G.S. Gooris, F.E. Dubbelaar, and M. Ponec Phase behaviour of stratum corneum lipid mixtures based on human ceramides: the role of natural and synthetic ceramide 1 J. Invest. Dermatol. 118 2002 606 617 (Pubitemid 34309979)
4. D.C. Carrer, C. Vermehren, and L.A. Bagatolli Pig skin structure and transdermal delivery of liposomes: a two photon microscopy study J. Control. Release 132 2008 12 20
5. J. Caussin, G.S. Gooris, M. Janssens, and J.A. Bouwstra Lipid organization in human and porcine stratum corneum differs widely, while lipid mixtures with porcine ceramides model human stratum corneum lipid organization very closely Biochim. Biophys. Acta 1778 2008 1472 1482
6. G. Cevc, and U. Vierl Nanotechnology and the transdermal route, a state of the art review and critical appraisal J. Control. Release 141 2010 277 299
7. C. Curdy, A. Naik, Y.N. Kalia, I. Alberti, and R.H. Guy Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo Int. J. Pharm. 271 2004 251 256 (Pubitemid 38210103)
8. G.M. El Maghraby, B.W. Barry, and A.C. Williams Liposomes and skin: from drug delivery to model membranes Eur. J. Pharm. Sci. 34 2008 203 222
9. L.M. Ensign, B.C. Tang, Y.Y. Wang, T.A. Tse, T. Hoen, R. Cone, and J. Hanes Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus Sci. Transl. Med. 4 2012 138
10. M.V. Frailea, B. Patrón-Gallardoa, G. López- RodrÍgueza, and P. Carmona FT-IR study of multilamellar lipid dispersions containing cholesteryl linoleate and dipalmitoylphosphatidylcholine Chem. Phys. Lipids 97 1999 119 128 (Pubitemid 29094599)
11. Gorcea, M., Hadgraft, J., Moore, D.J., Lane, M.E., 2012. In vivo barrier challenge and initial recovery in human facial skin. Skin Res. Technol, in press. doi: 10.1111/j.1600-0846.2012.00654.x.
12. A. Hasanovic, R. Winkler, G.P. Resch, and C. Valenta Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir Eur. J. Pharm. Biopharm. 79 2011 76 81
13. W. He, X. Guo, L. Xiao, and M. Feng Study on the mechanisms of chitosan and its derivatives used as transdermal penetration enhancers Int. J. Pharm. 382 2009 234 243
14. H.M. Heise, L. Kuepper, W. Pittermann, and M. Kietzmann Epidermal in vivo and in vitro studies by attenuated total reflection spectroscopy using a novel mid-infrared fibre probe R. Marks, J.L. Lévêque, R. Voegeli, The Essential Stratum Corneum 2002 Martin Dunitz Ltd. London 257
15. J.R. Hill, and P.W. Wertz Structures of the ceramides from porcine palatal stratum corneum Lipids 44 2009 291 295
16. A. Hussain, and F. Ahsan The vagina as a route for systemic drug delivery J. Control. Release 103 2005 301 313 (Pubitemid 40342532)
17. V. Klang, J.C. Schwarz, A. Hartl, and C. Valenta Facilitating in vitro tape stripping: application of infrared densitometry for quantification of porcine stratum corneum proteins Skin Pharmacol. Physiol. 24 2011 256 268
18. V. Klang, J.C. Schwarz, B. Lenobel, M. Nadj, J. Auböck, M. Wolzt, and C. Valenta In vitro vs. in vivo tape stripping: validation of the porcine ear model and penetration assessment of novel sucrose stearate emulsions Eur. J. Pharm. Biopharm. 80 2012 604 614
19. A. Naik, and R.H. Guy Infrared spectroscopic and differential scanning calorimetric investigations of the stratum corneum barrier function R.O. Potts, R.H. Guy, Mechanisms of transdermal drug delivery 1997 Marcel Dekker Inc. New York 87 162
20. V.F. Patel, F. Liu, and M.B. Brown Modeling the oral cavity: in vitro and in vivo evaluations of buccal drug delivery systems J. Control. Release 161 2012 746 756
21. D.H. Oh, K.H. Chun, S.O. Jeon, J.W. Kang, and S. Lee Enhanced transbuccal salmon calcitonin (sCT) delivery: effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation Eur. J. Pharm. Biopharm. 79 2011 357 363
22. G. Rodríguez, L. Barbosa-Barros, L. Rubio, M. Cócera, A. Díez, J. Estelrich, R. Pons, J. Caelles, A. De la Maza, and O. López Conformational changes in stratum corneum lipids by effect of bicellar systems Langmuir 25 2009 10595 10603
23. S. Sakuyama, C. Hirabayashi, J. Hasegawa, and S. Yoshida Analysis of human face skin surface molecules in situ by Fourier-transform infrared spectroscopy Skin Res. Technol. 16 2010 151 160
24. J.C. Schwarz, H. Kählig, N.B. Matsko, M. Kratzel, M. Husa, and C. Valenta Decrease of liposomal size and retarding effect on fluconazole skin permeation by lysine derivatives J. Pharm. Sci. 100 2011 2911 2919
25. J.C. Schwarz, V. Klang, M. Hoppel, D. Mahrhauser, and C. Valenta Natural microemulsions: formulation design and skin interaction Eur. J. Pharm. Biopharm. 81 2012 557 562
26. N. Sekkat, Y.N. Kalia, and R.H. Guy Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo J. Pharm. Sci. 91 2002 2376 2381 (Pubitemid 35231200)
27. N.K. Swarnakar, V. Jain, V. Dubey, D. Mishra, and N.K. Jain Enhanced oromucosal delivery of progesterone via hexosomes Pharm. Res. 24 2007 2223 2230 (Pubitemid 350060713)
28. C. Valenta The use of mucoadhesive polymers in vaginal delivery Adv. Drug Deliv. Rev. 57 2005 1692 1712 (Pubitemid 41444256)
29. P. Van der Bijl, and A.D. Van Eyk Human vaginal mucosa as a model of buccal mucosa for in vitro permeability studies: an overview Curr. Drug Deliv. 1 2004 129 135
30. D.D. Verma, and A. Fahr Confocal laser scanning microscopy: an excellent tool for tracking compounds in the skin E.W. Smith, H.I. Maibach, Percutaneous Penetration Enhancers second ed. 2006 CRC press Boca Raton 335 357
31. R. Warren, P.W. Wertz, T. Kirkbride, M. Brunner, and M.C. Gross Comparative analysis of skin surface lipids of the labia majora, inner thigh, and forearm Skin Pharmacol. Physiol. 24 2011 294 299
32. P.W. Wertz, D.C. Swartzendruber, and C.A. Squier Regional variation in the structure and permeability of oral mucosa and skin Adv. Drug Del. Rev. 12 1993 1 12 (Pubitemid 23332994)
33. P.W. Wertz, and B. Van den Bergh The physical, chemical and functional properties of lipids in the skin and other biological barriers Chem. Phys. Lipids 91 1998 85 96 (Pubitemid 28142956)