In vitro vs. in vivo tape stripping: Validation of the porcine ear model and penetration assessment of novel sucrose stearate emulsions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 3, 2012, Pages 604-614

  Klang, Victoria ^a   Schwarz, Julia C ^a   Lenobel, Barbara ^a   Nadj, Martina ^a   Auböck, Josef ^b   Wolzt, Michael ^c   Valenta, Claudia ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b KEPLER UNIVERSITY HOSPITAL   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Nanoemulsion; Porcine ears; Skin penetration; Sucrose stearate; Tape stripping

Indexed keywords

2 PROPANOL; ADHESIVE AGENT; ALCOHOL; CARBOMER; CURCUMIN; FLUORESCEIN SODIUM; LIPID; OLEIC ACID; PHOSPHATIDYLCHOLINE; PROPYLENE GLYCOL; PROTEIN; SORBATE POTASSIUM; STEARIC ACID; SUCROSE; SUCROSE STEARATE; UNCLASSIFIED DRUG; WATER; WATER OIL CREAM;

ADHESIVE TAPE STRIPPING; ADULT; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; CONTROLLED STUDY; CORNEOCYTE; DENSITOMETRY; DERMATOLOGICAL PROCEDURES; DRUG PENETRATION; EAR; FEMALE; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN EXPERIMENT; HUMAN VERSUS ANIMAL COMPARISON; HYDROGEL; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; LIPOPHILICITY; MALE; NANOEMULSION; NEAR INFRARED SPECTROSCOPY; NONHUMAN; NORMAL HUMAN; SKIN CELL; SKIN PENETRATION; SKIN WATER LOSS; STRATUM CORNEUM; SWINE;

ADOLESCENT; ADULT; ANIMALS; CURCUMIN; EAR, EXTERNAL; EMULSIONS; FEMALE; FLUORESCEIN; FOREARM; HUMANS; HYDROGEL; MALE; NANOTECHNOLOGY; SKIN; SKIN ABSORPTION; SUCROSE; SURFACE PROPERTIES; SWINE; YOUNG ADULT;

EID: 84858152802     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.11.009     Document Type: Article

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