Novel effect of paeonol on the formation of foam cells: Promotion of LXRα-ABCA1 dependent cholesterol efflux in macrophages

American Journal of Chinese Medicine

Volumn 41, Issue 5, 2013, Pages 1079-1096

  Zhao, Jin Feng ^a   Jim Leu, Shr Jeng ^a   Shyue, Song Kun ^b   Su, Kuo Hui ^a   Wei, Jeng ^c   Lee, Tzong Shyuan ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c CHENG HSIN GENERAL HOSPITAL   (Taiwan)

Author keywords

ABCA1; Atherosclerosis; Foam Cell; LXR ; Paeonol

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G1; APOENZYME; APOLIPOPROTEIN E; CHOLESTEROL; LIVER X RECEPTOR ALPHA; MESSENGER RNA; NEUTRALIZING ANTIBODY; OXIDIZED LOW DENSITY LIPOPROTEIN; PAEONIA SUFFRUTICOSA EXTRACT; PEONOL; SCAVENGER RECEPTOR; SMALL INTERFERING RNA;

ANIMAL CELL; AORTA; ARTICLE; ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; CELL NUCLEUS; CHINESE MEDICINE; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG EFFICACY; FOAM CELL; GENE SILENCING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPERLIPIDEMIA; MACROPHAGE; MOUSE; NONHUMAN; PAEONIA SUFFRUTICOSA; PROTEIN EXPRESSION; UPREGULATION;

ACETOPHENONES; ANIMALS; ATHEROSCLEROSIS; ATP BINDING CASSETTE TRANSPORTER 1; CELL CULTURE TECHNIQUES; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; FOAM CELLS; GENE EXPRESSION; INFLAMMATION MEDIATORS; LIPOPROTEINS, LDL; MALE; MICE; MOLECULAR TARGETED THERAPY; ORPHAN NUCLEAR RECEPTORS; PHYTOTHERAPY; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84885901176     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X13500730     Document Type: Article

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