Study on the pharmacokinetics and metabolism of paeonol in rats treated with pure paeonol and an herbal preparation containing paeonol by using HPLC-DAD-MS method

Journal of Pharmaceutical and Biomedical Analysis

Volumn 46, Issue 4, 2008, Pages 748-756

  Xie, Ying ^a   Zhou, Hua ^a   Wong, Yuen Fan ^a   Xu, Hong Xi ^b   Jiang, Zhi Hong ^a   Liu, Liang ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

LC MS; Metabolite; Paeonol; Pharmacokinetic; QFGJS

Indexed keywords

HERBACEOUS AGENT; PEONOL; QINGFU GUANJIESHU; UNCLASSIFIED DRUG;

ANALYSIS; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DIODE ARRAY DETECTION; DOSE RESPONSE; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MEDICAL RESEARCH; METABOLITE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; TIME OF FLIGHT MASS SPECTROMETRY; VALIDATION PROCESS;

ACETOPHENONES; ANIMALS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; DRUGS, CHINESE HERBAL; MALE; QUALITY CONTROL; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 39149140358     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.11.046     Document Type: Article

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