Heme impairs the ball-and-chain inactivation of potassium channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 42, 2013, Pages

  Sahoo, Nirakar ^a   Goradia, Nishit ^b   Ohlenschläger, Oliver ^b   Schönherr, Roland ^a   Friedrich, Manfred ^a   Plass, Winfried ^a   Kappl, Reinhard ^c   Hoshi, Toshinori ^d   Heinemann, Stefan H ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

A type channel; Cysteine; Intrinsically disordered domain; N type inactivation; Nmr

Indexed keywords

CYSTEINE; HEME; HISTIDINE; PEPTIDE; POTASSIUM CHANNEL KV1.4;

ACTION POTENTIAL; AMINO TERMINAL SEQUENCE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ENZYME INACTIVATION; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; VESTIBULE; XENOPUS;

A-TYPE CHANNEL; CYSTEINE; INTRINSICALLY DISORDERED DOMAIN; N-TYPE INACTIVATION; NMR;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; HEME; ION TRANSPORT; KV1.4 POTASSIUM CHANNEL; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; XENOPUS LAEVIS;

EID: 84885776082     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313247110     Document Type: Article

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