The Gdac1 locus modifies spontaneous and Salmonella-induced colitis in mice deficient in either Gpx2 or Gpx1 gene

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 1273-1283

  Steven Esworthy, R ^a   Kim, Byung Wook ^a   Wang, Yufeng ^b   Gao, Qiang ^b   Doroshow, James H ^c   Leto, Thomas L ^d   Chu, Fong Fong ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

DUOX2; Free radicals; Gdac1; GPX deficiency associated colitis locus 1; GPX1; GPX2; Gut dysbiosis; Metronidazole; Mouse genetics; Salmonella enterica serotype typhimurium; Selenium

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CD14 ANTIGEN; CRYOPYRIN; CYCLOOXYGENASE 2; GAMMA INTERFERON; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE PEROXIDASE 2; GPX DEFICIENCY ASSOCIATED COLITIS 1; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VILLIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL GROWTH; COLITIS; COLON MUCOSA; GENE EXPRESSION; GOBLET CELL; INNATE IMMUNITY; MACROPHAGE; MITOSIS; MOUSE; NATURAL KILLER CELL; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; WILD TYPE;

MUS; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM;

DUOX2; FREE RADICALS; GDAC1; GPX-DEFICIENCY-ASSOCIATED-COLITIS LOCUS-1; GPX1; GPX2; GUT DYSBIOSIS; METRONIDAZOLE; MOUSE GENETICS; SALMONELLA ENTERICA SEROTYPE TYPHIMURIUM; SELENIUM;

ALLELES; ANIMALS; APOPTOSIS; CELL PROLIFERATION; COLITIS; CYCLOOXYGENASE 2; DYSBIOSIS; EPITHELIAL CELLS; GENETIC VARIATION; GLUTATHIONE PEROXIDASE; GOBLET CELLS; INFLAMMATION; MEMBRANE GLYCOPROTEINS; METRONIDAZOLE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADPH OXIDASE; NOD2 SIGNALING ADAPTOR PROTEIN; RNA, MESSENGER; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885753275     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.09.013     Document Type: Article

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