Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 42, 2013, Pages 17053-17058

  Ono, Masanori ^a,b   Yin, Ping ^a   Navarro, Antonia ^a   Moravek, Molly B ^a   Coon V, John S ^a   Druschitz, Stacy A ^a   Serna, Vanida Ann ^a   Qiang, Wenan ^a   Brooks, David C ^a   Malpani, Saurabh S ^a   Ma, Jiajia ^a   Ercan, Cihangir Mutlu ^a   Mittal, Navdha ^a   Monsivais, Diana ^a   Dyson, Matthew T ^a   Yemelyanov, Alex ^a   Maruyama, Tetsuo ^b   Chakravarti, Debabrata ^a   Kim, J Julie ^a   Kurita, Takeshi ^a   Gottardi, Cara J ^a   Bulun, Serdar E ^a   more..

^a NORTHWESTERN UNIVERSITY   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Paracrine signaling; Tumor biology; WNT catenin signaling

Indexed keywords

AXIN2 PROTEIN; BETA CATENIN; ESTROGEN; GROWTH FACTOR; PROGESTERONE; T CELL FACTOR PROTEIN; T LYMPHOCYTE FACTOR 4; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT PROTEIN; WNT11 PROTEIN; WNT16 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER STEM CELL; CANCER TISSUE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL LINE; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MYOMETRIUM; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; TUMOR GROWTH; UTERUS MYOMA;

PARACRINE SIGNALING; TUMOR BIOLOGY; WNT/Β-CATENIN SIGNALING;

ADULT; ANIMALS; AXIN PROTEIN; BETA CATENIN; CELL PROLIFERATION; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEIOMYOMA; MICE; MICE, INBRED NOD; MICE, SCID; MIDDLE AGED; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; PARACRINE COMMUNICATION; PREGNANCY; PROGESTERONE; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN; UTERINE NEOPLASMS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84885699845     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313650110     Document Type: Article

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