Uterine myomas: An overview of development, clinical features, and management

Obstetrics and Gynecology

Volumn 104, Issue 2, 2004, Pages 393-406

  Wallach, Edward E ^a   Vlahos, Nikos F ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUSERELIN; GESTAGEN; GONADORELIN DERIVATIVE; LEUPRORELIN; MEDROGESTONE; MEDROXYPROGESTERONE ACETATE; MIFEPRISTONE; NAFARELIN; NORETHISTERONE;

CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; FEMALE INFERTILITY; HORMONAL THERAPY; HUMAN; HYSTERECTOMY; HYSTEROSALPINGOGRAPHY; HYSTEROSCOPY; IRON DEFICIENCY ANEMIA; LAPAROSCOPIC SURGERY; LEIOMYOMA; MALIGNANT TRANSFORMATION; MENSTRUATION; MYOMECTOMY; NEODYMIUM LASER; NUCLEAR MAGNETIC RESONANCE IMAGING; PAIN; PRIORITY JOURNAL; REVIEW; TREATMENT INDICATION; TUMOR GROWTH; ULTRASOUND; UTERINE ARTERY EMBOLIZATION; UTERUS MYOMA; UTERUS TUMOR; DECISION TREE; PATHOLOGY; RADIOGRAPHY; UTERUS CANCER;

DECISION TREES; FEMALE; HUMANS; HYSTERECTOMY; LEIOMYOMA; UTERINE NEOPLASMS;

EID: 4344563483     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.AOG.0000136079.62513.39     Document Type: Review

References (88)

1. Levy B, Mukherjee T, Hirschhorn K. Molecular cytogenetic analysis of uterine leiomyoma and leiomyosarcoma by comparative genomic hybridization. Cancer Genet Cytogenet 2000;121:1-8.
2. Montaque A, Swartz DP, Woodruff JD. Sarcoma arising in leiomyoma of uterus: factors influencing prognosis. Am J Obstet Gynecol 1965;92:421-7.
3. Corscaden JA, Singh BP. Leiomyosarcoma of the uterus. Am J Obstet Gynecol 1958;75:149-55.
4. Parker WH, Fu YS, Berek JS. Uterine sarcoma in patients operated on for presumed leiomyoma and rapidly growing leiomyoma. Obstet Gynecol 1994;83:414-8.
5. Buttram VC Jr, Reiter RC. Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril 1981;36:433-45.
6. Mampaey S, De Schepper AM, Naudts P, Buytaert G. Uterine leiomyoma during pregnancy. J Belge Radiol 1996;79:275.
7. Farber M, Conrad S, Heinrichs WL, Herrmann WL. Estradiol binding by fibroid tumors and normal myometrium. Obstet Gynecol 1972;40:479-86.
8. Cramer SF, Patel A. The frequency of uterine leiomyomas. Am J Clin Pathol 1990;94:435-8.
9. Lumsden MA, Wallace EM. Clinical presentation of uterine fibroids. Baillieres Clin Obstet Gynaecol 1998;12: 177-95.
10. Ozumba BC, Megafu UC, Igwegbe AO. Uterine fibroids: clinical presentation and management in a Nigerian teaching hospital. Ir Med J 1992;85:158-9.
11. Farrer-Brown G, Beilby JO, Tarbit MH. The vascular patterns in myomatous uteri. J Obstet Gynaecol Br Commonw 1970;77:967-75.
12. Farrer-Brown G, Beilby JO, Tarbit MH. Venous changes in the endometrium of myomatous uteri. Obstet Gynecol 1971;38:743-51.
13. Sehgal N, Haskins AL. The mechanism of uterine bleeding in the presence of fibromyomas. Am Surg 1960;26:21-3.
14. Novak E, Novak ER. Gynecologic and obstetric pathology. 4th ed. Philadelphia (PA): W. B. Saunders Company; 1958.
15. Stewart EA, Nowak RA. Leiomyoma-related bleeding: a classic hypothesis updated for the molecular era. Hum Reprod Update 1996;2:295-306.
16. Monga AK, Woodhouse CR, Stanton SL. Pregnancy and fibroids causing simultaneous urinary retention and ureteric obstruction. Br J Urol 1996;77:606-7.
17. Fernandez H, Sefrioui O, Virelizier C, Gervaise A, Gomel V, Frydman R. Hysteroscopic resection of submucosal myomas in patients with infertility. Hum Reprod 2001;16: 1489-92.
18. Goldenberg M, Sivan E, Sharabi Z, Bider D, Rabinovici J, Seidman DS. Outcome of hysteroscopic resection of submucous myomas for infertility. Fertil Steril 1995;64: 714-6.
19. Bajekal N, Li TC. Fibroids, infertility and pregnancy wastage. Hum Reprod Update 2000;6:614-20.
20. Seoud MA, Patterson R, Muasher SJ, Coddington CC 3rd. Effects of myomas or prior myomectomy on in vitro fertilization (IVF) performance. J Assist Reprod Genet 1992;9:217-21.
21. Propst AM, Hill JA 3rd. Anatomic factors associated with recurrent pregnancy loss. Semin Reprod Med 2000;18: 341-50.
22. Benson CB, Chow JS, Chang-Lee W, Hill JA 3rd, Doubilet PM. Outcome of pregnancies in women with uterine leiomyomas identified by sonography in the first trimester. J Clin Ultrasound 2001;29:261-4.
23. Campo S, Campo V, Gambadauro P. Reproductive outcome before and after laparoscopic or abdominal myomectomy for subserous or intramural myomas. Eur J Obstet Gynecol Reprod Biol 2003;110:215-9.
24. Li TC, Mortimer R, Cooke ID. Myomectomy: a retrospective study to examine reproductive performance before and after surgery. Hum Reprod 1999;14:1735-40.
25. Sudik R, Husch K, Steller J, Daume E. Fertility and pregnancy outcome after myomectomy in sterility patients. Eur J Obstet Gynecol Reprod Biol 1996;65:209-14.
26. Rosati P, Exacoustos C, Mancuso S. Longitudinal evaluation of uterine myoma growth during pregnancy: a sonographic study. J Ultrasound Med 1992;11:511-5.
27. Tada S, Tsukioka M, Ishii C, Tanaka H, Mizunuma K. Computed tomographic features of uterine myoma. J Comput Assist Tomogr 1981;5:866-9.
28. Scoutt LM, McCarthy SM. Applications of magnetic resonance imaging to gynecology. Top Magn Reson Imaging 1990;2:37-49.
29. Lefebvre G, Vilos G, Allaire C, Jeffrey J, Arneja J, Birch C, et al. The management of uterine leiomyomas. J Obstet Gynaecol Can 2003;25:396-418, quiz 419-22.
30. Iverson RE Jr, Chelmow D, Strohbehn K, Waldman L, Evantash EG. Relative morbidity of abdominal hysterectomy and myomectomy for management of uterine leiomyomas. Obstet Gynecol 1996;88:415-9.
31. Farrell SA, Kieser K. Sexuality after hysterectomy. Obstet Gynecol 2000;95:1045-51.
32. Weber AM, Walters MD, Schover LR, Church JM, Piedmonte MR. Functional outcomes and satisfaction after abdominal hysterectomy. Am J Obstet Gynecol 1999;181: 530-5.
33. Kjerulff KH, Langenberg PW, Rhodes JC, Harvey LA, Guzinski GM, Stolley PD. Effectiveness of hysterectomy. Obstet Gynecol 2000;95:319-26.
34. Rowe MK, Kanouse DE, Mittman BS, Bernstein SJ. Quality of life among women undergoing hysterectomies. Obstet Gynecol 1999;93:915-21.
35. Harkki-Siren P, Sjoberg J, Tütinen A. Urinary tract injuries after hysterectomy. Obstet Gynecol 1998;92:113-8.
36. Thakar R, Ayers S, Clarkson P, Stanton S, Manyonda I. Outcomes after total versus subtotal abdominal hysterectomy. N Engl J Med 2002;347:1318-25.
37. Learman LA, Summitt RL Jr, Varner RE, McNeeley SG, Goodman-Gruen D, Richter HE, et al. A randomized comparison of total or supracervical hysterectomy: surgical complications and clinical outcomes. Obstet Gynecol 2003;102:453-62.
38. Sheth S, Malpani A. Routine prophylactic oophorectomy at the time of vaginal hysterectomy in postmenopausal women. Arch Gynecol Obstet 1992;251:87-91.
39. Sheth SS. The place of oophorectomy at vaginal hysterectomy. Br J Obstet Gynaecol 1991;98:662-6.
40. Smale LE, Smale ML, Wilkening RL, Mundy CF, Ewing TL. Salpingo-oophorectomy at the time of vaginal hysterectomy. Am J Obstet Gynecol 1978;131:122-8.
41. Wilcox LS, Koonin LM, Pokras R, Strauss LT, Xia Z, Peterson HB. Hysterectomy in the United States, 1988-1990. Obstet Gynecol 1994;83:549-55.
42. Pritts EA. Fibroids and infertility: a systematic review of the evidence. Obstet Gynecol Surv 2001;56:483-91.
43. Ginsburg ES, Benson CB, Garfield JM, Gleason RE, Friedman AJ. The effect of operative technique and uterine size on blood loss during myomectomy: a prospective randomized study. Fertil Steril 1993;60:956-62.
44. Classic pages in obstetrics and gynecology. Enucleation of uterine fibroids: William Alexander British Gynaecological Journal, vol. 14, pp. 47-61, 1898. Am J Obstet Gynecol 1977;128:811.
45. Classic pages in obstetrics and gynecology. Enucleation of uterine fibroids: William Alexander British Gynaecological Journal, vol. 14, pp. 47-61, 1898. Am J Obstet Gynecol 1977;128:811.
46. Bonney V. The technique and results of myomectomy. Lancet 1931;220:171-3.
47. Rubin I. Progress in myomectomy. Am J Obstet Gynecol 1942;44:196-212.
48. Mohammed NB, NoorAli R, AnandaKumar C. Uterine fibroid: clinical presentation and relative morbidity of abdominal myomectomy and total abdominal hysterectomy, in a teaching hospital of Karachi, Pakistan. Singapore Med J 2002;43:289-95.
49. Rouzi AA, Al-Noury AI, Shobokshi AS, Jamal HS, Abduljabbar HS. Abdominal myomectomy versus abdominal hysterectomy for symptomatic and big uterine fibroids. Saudi Med J 2001;22:984-6.
50. Sawin SW, Pilevsky ND, Berlin JA, Barnhart KT. Comparability of perioperative morbidity between abdominal myomectomy and hysterectomy for women with uterine leiomyomas. Am J Obstet Gynecol 2000;183:1448-55.
51. West CP. Hysterectomy and myomectomy by laparotomy. Baillieres Clin Obstet Gynaecol 1998;12:317-35.
52. Fauconnier A, Chapron C, Babaki-Fard K, Dubuisson JB. Recurrence of leiomyomata after myomectomy. Hum Reprod Update 2000;6:595-602.
53. Candiani GB, Fedele L, Parazzini F, Villa L. Risk of recurrence after myomectomy. Br J Obstet Gynaecol 1991;98:385-9.
54. Malone LJ. Myomectomy: recurrence after removal of solitary and multiple myomas. Obstet Gynecol 1969;34: 200-3.
55. Doridot V, Dubuisson JB, Chapron C, Fauconnier A, Babaki-Fard K. Recurrence of leiomyomata after laparoscopic myomectomy. J Am Assoc Gynecol Laparosc 2001; 8:495-500.
56. Nezhat FR, Roemisch M, Nezhat CH, Seidman DS, Nezhat CR. Recurrence rate after laparoscopic myomectomy. J Am Assoc Gynecol Laparosc 1998;5:237-40.
57. Cohen LS, Valle RF. Role of vaginal sonography and hysterosonography in the endoscopic treatment of uterine myomas. Fertil Steril 2000;73:197-204.
58. Goldfarb HA. Myoma coagulation (myolysis). Obstet Gynecol Clin North Am 2000;27:421-30.
59. Donnez J, Squifflet J, Polet R, Nisolle M. Laparoscopic myolysis. Hum Reprod Update 2000;6:609-13.
60. Dubuisson JB, Chapron C. Laparoscopic myomectomy and myolysis. Baillieres Clin Obstet Gynaecol 1995;9: 717-28.
61. Cowan BD, Sewell PE, Howard JC, Arriola RM, Robinette LG. Interventional magnetic resonance imaging cryotherapy of uterine fibroid tumors: preliminary observation. Am J Obstet Gynecol 2002;186:1183-7.
62. Pelage JP, Soyer P, Le Dref O, Dahan H, Coumbaras J, Kardache M, et al. Uterine arteries: bilateral catheterization with a single femoral approach and a single 5-F catheter-technical note. Radiology 1999;210: 573-5.
63. Hurst BS, Stackhouse DJ, Matthews ML, Marshburn PB. Uterine artery embolization for symptomatic uterine myomas. Ferril Steril 2000;74:855-69.
64. Ravina JH, Vigneron NC, Aymard A, Le Dref O, Merland JJ. Pregnancy after embolization of uterine myoma: report of 12 cases. Fertil Steril 2000;73:1241-3.
65. Tiltman AJ. The effect of progestins on the mitotic activity of uterine fibromyomas. Int J Gynecol Pathol 1985;4: 89-96.
66. Vikhliaeva EM. Conservative treatment of patients with uterine myoma [in Russian]. Akush Ginekol (Mosk) 1987: 63-7.
67. Vikhliaeva EM, Uvarova EV, Samedova N. The mechanism of the therapeutic effect of norethisterone in hyperplastic diseases of the endo- and myometrium in women of reproductive age [in Russian]. Vopr Onkol 1990;36: 683-9.
68. Eisinger SH, Meldrum S, Fiscella K, le Roux HD, Guzick DS. Low-dose mifepristone for uterine leiomyomata. Obstet Gynecol 2003;101:243-50.
69. Murphy AA, Morales AJ, Kettel LM, Yen SS. Regression of uterine leiomyomata to the antiprogesterone RU486: dose-response effect. Fertil Steril 1995;64:187-90.
70. Zeng C, Gu M, Huang H. A clinical control study on the treatment of uterine leiomyoma with gonadotrophin releasing hormone agonist or mifepristone [in Chinese]. Zhonghua Fu Chan Ke Za Zhi 1998;33:490-2.
71. Yang Y, Zheng S, Zhang Z. Effects of mifepristone on gene expression of epidermal growth factor in human uterine leiomyoma [in Chinese]. Zhonghua Fu Chan Ke Za Zhi 1998;33:38-9.
72. Yang Y, Zheng S, Li K. Treatment of uterine leiomyoma by two different doses of mifepristone [in Chinese]. Zhonghua Fu Chan Ke Za Zhi 1996;31:624-6.
73. Baird DT, West CP. Medical management of fibroids. Br Med J (Clin Res Ed) 1988;296:1684-5.
74. Golan A. GnRH analogues in the treatment of uterine fibroids. Hum Reprod 1996;11(suppl 3):33-41.
75. Andreyko JL, Blumenfeld Z, Marshall LA, Monroe SE, Hricak H, Jaffe RB. Use of an agonistic analog of gonadotropin-releasing hormone (nafarelin) to treat leiomyomas: assessment by magnetic resonance imaging. Am J Obstet Gynecol 1988;158:903-10.
76. Maheux R, Lemay A, Merat P. Use of intranasal luteinizing hormone-releasing hormone agonist in uterine leiomyomas. Fertil Steril 1987;47:229-33.
77. Schlaff WD, Zerhouni EA, Huth JA, Chen J, Damewood MD, Rock JA. A placebo-controlled trial of a depot gonadotropin-releasing hormone analogue (leuprolide) in the treatment of uterine leiomyomata. Obstet Gynecol 1989; 74:856-62.
78. Lethaby A, Vollenhoven B, Sowter M. Pre-operarive GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids (Cochrane Review). In: The Cochrane Library, Issue 2, 2001. Oxford: Update Software.
79. Stjernquist M. Treatment of uterine fibroids with GnRH-analogues prior to hysterectomy. Acta Obstet Gynecol Scand Suppl 1997;164:94-7.
80. Friedman AJ, Daly M, Juneau-Norcross M, Fine C, Rein MS. Recurrence of myomas after myomectomy in women pretreated with leuprolide acetate depot or placebo. Fertil Steril 1992;58:205-8.
81. Crosignani PG, Vercellini P, Meschia M, Oldani S, Bramante T. GnRH agonists before surgery for uterine leiomyomas: a review. J Reprod Med 1996;41:415-21.
82. Davies A, Hart R, Magos AL. The excision of uterine fibroids by vaginal myomectomy: a prospective study. Fertil Steril 1999;71:961-4.
83. Chan AH, Fujimoto VY, Moore DE, Martin RW, Vaezy S. An image-guided high intensity focused ultrasound device for uterine fibroids treatment. Med Phys 2002;29: 2611-20.
84. Keshavarzi A, Vaezy S, Noble LM, Paum MK, Fujimoto VY. Treatment of uterine fibroid tumors in as in situ rat model using high-intensity focused ultrasound. Fertil Steril 2003;80:761-7.
85. Vaezy S, Fujimoto VY, Walker C, Martin RW, Chi EY, Crum LA. Treatment of uterine fibroid tumors in a nude mouse model using high-intensity focused ultrasound. Am J Obstet Gynecol 2000;183:6-11.
86. McLaughlin DS. Micro-laser myomectomy technique to enhance reproductive potential: a preliminary report. Lasers Surg Med 1982;2:107-27.
87. Baggish MS, Sze EHM, Morgan G. Hysteroscopic treatment of symptomatic submucous myoma uteri with the Nd:YAG laser. J Gynecol Surg 1989;5:27-36.
88. Kelly HA. Operative gynecology. New York (NY) : Appleton and Company; 1898.