-
1
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407: 249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
2
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 2007;7: 834-46.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
3
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285: 1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
4
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature 2005;438: 967-74.
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
5
-
-
79953244361
-
Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
-
Ebon JM, Kerbel RS. Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat Rev Clin Oncol 2011;8: 210-21.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 210-221
-
-
Ebon, J.M.1
Kerbel, R.S.2
-
7
-
-
34147171490
-
Endothelial cell migration during angiogenesis
-
Lamalice L, Le Boeuf F, Huot J. Endothelial cell migration during angiogenesis. Circ Res 2007;100: 782-94.
-
(2007)
Circ Res
, vol.100
, pp. 782-794
-
-
Lamalice, L.1
Le Boeuf, F.2
Huot, J.3
-
9
-
-
0028362876
-
Requirement of vascular integrin alpha v beta 3 for angiogenesis
-
Brooks PC, Clark RA, Cheresh DA: Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994;264: 569-71.
-
(1994)
Science
, vol.264
, pp. 569-571
-
-
Brooks, P.C.1
Clark, R.A.2
Cheresh, D.A.3
-
10
-
-
84859075784
-
VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution
-
Alexander RA, Prager GW, Mihaly-Bison J, Uhrin P, Sunzenauer S, Binder BR, et al. VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution. Cardiovasc Res 2012;94: 125-35.
-
(2012)
Cardiovasc Res
, vol.94
, pp. 125-135
-
-
Alexander, R.A.1
Prager, G.W.2
Mihaly-Bison, J.3
Uhrin, P.4
Sunzenauer, S.5
Binder, B.R.6
-
11
-
-
0026063532
-
Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol
-
Ploug M, Rønne E, Behrendt N, Jensen AL, Blasi F, Danø K. Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol. J Biol Chem 1991;266: 1926-33.
-
(1991)
J Biol Chem
, vol.266
, pp. 1926-1933
-
-
Ploug, M.1
Rønne, E.2
Behrendt, N.3
Jensen, A.L.4
Blasi, F.5
Danø, K.6
-
13
-
-
0036906177
-
UPAR: A versatile signaling orchestrator
-
Blasi F, Carmeliet P. uPAR: a versatile signaling orchestrator. Nat Rev Mol Cell Biol 2002;3: 932-43.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 932-943
-
-
Blasi, F.1
Carmeliet, P.2
-
14
-
-
0038364216
-
The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy
-
Sidenius N, Blasi F. The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy. Cancer Metastasis Rev 2003;22: 205-22.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 205-222
-
-
Sidenius, N.1
Blasi, F.2
-
15
-
-
33846978442
-
Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis
-
Shariat SF, Roehrborn CG, McConnell JD, Park S, Alam N, Wheeler TM, et al. Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis. J Clin Oncol 2007;25: 349-55.
-
(2007)
J Clin Oncol
, vol.25
, pp. 349-355
-
-
Shariat, S.F.1
Roehrborn, C.G.2
McConnell, J.D.3
Park, S.4
Alam, N.5
Wheeler, T.M.6
-
16
-
-
53249103673
-
Cleaved forms of the urokinase plasminogen activator receptor in plasma have diagnostic potential and predict postoperative survival in patients with ovarian cancer
-
Henic E, Borgfeldt C, Christensen IJ, Casslén B, Høyer-Hansen G. Cleaved forms of the urokinase plasminogen activator receptor in plasma have diagnostic potential and predict postoperative survival in patients with ovarian cancer. Clin Cancer Res 2008;14: 5785-93.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5785-5793
-
-
Henic, E.1
Borgfeldt, C.2
Christensen, I.J.3
Casslén, B.4
Høyer-Hansen, G.5
-
17
-
-
52049092484
-
Intact and cleaved uPAR forms: Diagnostic and prognostic value in cancer
-
Rasch MG, Lund IK, Almasi CE, Hoyer-Hansen G. Intact and cleaved uPAR forms: diagnostic and prognostic value in cancer. Front Biosci 2008;13: 6752-62.
-
(2008)
Front Biosci
, vol.13
, pp. 6752-6762
-
-
Rasch, M.G.1
Lund, I.K.2
Almasi, C.E.3
Hoyer-Hansen, G.4
-
18
-
-
33947321575
-
UPAR-uPA-PAI-1 interactions and signaling: A vascular biologist's view
-
Binder BR, Mihaly J, Prager GW. uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view. Thromb Haemost 2007;97: 336-42.
-
(2007)
Thromb Haemost
, vol.97
, pp. 336-342
-
-
Binder, B.R.1
Mihaly, J.2
Prager, G.W.3
-
19
-
-
0035721955
-
Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis
-
Pepper MS. Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis. Arterioscler Thromb Vasc Biol 2001;21: 1104-17.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1104-1117
-
-
Pepper, M.S.1
-
20
-
-
78650006378
-
The soluble form of urokinase receptor promotes angiogenesis through its Ser88-Arg-Ser-Arg-Tyr92 chemotactic sequence
-
Bifulco K, Longanesi-Cattani I, Gala M, DI Carluccio G, Masucci MT, Pavone V, et al. The soluble form of urokinase receptor promotes angiogenesis through its Ser88-Arg-Ser-Arg-Tyr92 chemotactic sequence. J Thromb Haemost 2010;8: 2789-99.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 2789-2799
-
-
Bifulco, K.1
Longanesi-Cattani, I.2
Gala, M.3
Carluccio G, D.I.4
Masucci, M.T.5
Pavone, V.6
-
21
-
-
0037022391
-
The fibrinolytic receptor for urokinase activates the G proteincoupled chemotactic receptor FPRL1/LXA4R
-
Resnati M, Pallavicini I, Wang JM, Oppenheim J, Serhan CN, Romano M, et al. The fibrinolytic receptor for urokinase activates the G proteincoupled chemotactic receptor FPRL1/LXA4R. Proc Natl Acad Sci USA 2002;99: 1359-64.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1359-1364
-
-
Resnati, M.1
Pallavicini, I.2
Wang, J.M.3
Oppenheim, J.4
Serhan, C.N.5
Romano, M.6
-
22
-
-
21644472064
-
Cross-talk between fMLP and vitronectin receptors triggered by urokinase receptor-derived SRSRY peptide
-
Gargiulo L, Longanesi-Cattani I, Bifulco K, Franco P, Raiola R, Campiglia P, et al. Cross-talk between fMLP and vitronectin receptors triggered by urokinase receptor-derived SRSRY peptide. J Biol Chem 2005;280: 25225-32.
-
(2005)
J Biol Chem
, vol.280
, pp. 25225-25232
-
-
Gargiulo, L.1
Longanesi-Cattani, I.2
Bifulco, K.3
Franco, P.4
Raiola, R.5
Campiglia, P.6
-
23
-
-
84866708012
-
Single amino acid substitutions in the chemotactic sequence of urokinase receptor modulate cell migration and invasion
-
Bifulco K, Longanesi-Cattani I, Franco P, Pavone V, Mugione P, Di Carluccio G, et al. Single amino acid substitutions in the chemotactic sequence of urokinase receptor modulate cell migration and invasion. PLoS One 2012;7:e44806.
-
(2012)
PLoS One
, vol.7
-
-
Bifulco, K.1
Longanesi-Cattani, I.2
Franco, P.3
Pavone, V.4
Mugione, P.5
Di Carluccio, G.6
-
24
-
-
40849140607
-
An urokinase receptor antagonist that inhibits cell migration by blocking the formyl peptide receptor
-
Bifulco K, Longanesi-Cattani I, Gargiulo L, Maglio O, Cataldi M, De Rosa M, et al. An urokinase receptor antagonist that inhibits cell migration by blocking the formyl peptide receptor. FEBS Lett 2008;582: 1141-6.
-
(2008)
FEBS Lett
, vol.582
, pp. 1141-1146
-
-
Bifulco, K.1
Longanesi-Cattani, I.2
Gargiulo, L.3
Maglio, O.4
Cataldi, M.5
De Rosa, M.6
-
25
-
-
70349484458
-
Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis
-
Carriero MV, Longanesi-Cattani I, Bifulco K, Maglio O, Lista L, Barbieri A, et al. Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis. Mol Cancer Ther 2009;8: 2708-17.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2708-2717
-
-
Carriero, M.V.1
Longanesi-Cattani, I.2
Bifulco, K.3
Maglio, O.4
Lista, L.5
Barbieri, A.6
-
26
-
-
77949439845
-
In vitro angiogenesis: Endothelial cell tube formation on gelled basement membrane extract
-
Arnaoutova I, Kleinman HK. In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract. Nat Protoc 2010; 5: 628-35.
-
(2010)
Nat Protoc
, vol.5
, pp. 628-635
-
-
Arnaoutova, I.1
Kleinman, H.K.2
-
27
-
-
0025835870
-
A soluble, ligand binding mutant of the human urokinase plasminogen activator receptor
-
Masucci MT, Pedersen N, Blasi F. A soluble, ligand binding mutant of the human urokinase plasminogen activator receptor. J Biol Chem 1991;266: 8655-8.
-
(1991)
J Biol Chem
, vol.266
, pp. 8655-8658
-
-
Masucci, M.T.1
Pedersen, N.2
Blasi, F.3
-
28
-
-
0028090482
-
Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies
-
Carriero MV, Franco P, Del Vecchio S, Massa O, Botti G, D'Aiuto G, et al. Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies. Cancer Res 1994;54: 5445-54.
-
(1994)
Cancer Res
, vol.54
, pp. 5445-5454
-
-
Carriero, M.V.1
Franco, P.2
Del Vecchio, S.3
Massa, O.4
Botti, G.5
D'Aiuto, G.6
-
29
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997;88: 277-85.
-
(1997)
Cell
, vol.88
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
Fukai, N.4
Vasios, G.5
Lane, W.S.6
-
30
-
-
0032886483
-
Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels
-
Yang S, Graham J, Kahn JW, Schwartz EA, Gerritsen ME. Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels. Am J Pathol 1999;155: 887-95.
-
(1999)
Am J Pathol
, vol.155
, pp. 887-895
-
-
Yang, S.1
Graham, J.2
Kahn, J.W.3
Schwartz, E.A.4
Gerritsen, M.E.5
-
31
-
-
84867676788
-
Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays
-
Limame R, Wouters A, Pauwels B, Fransen E, Peeters M, Lardon F, et al. Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays. PLoS One 2012;7:e46536.
-
(2012)
PLoS One
, vol.7
-
-
Limame, R.1
Wouters, A.2
Pauwels, B.3
Fransen, E.4
Peeters, M.5
Lardon, F.6
-
32
-
-
0037406938
-
Quantitative assessment of angiogenic responses by the directed in vivo angiogenesis assay
-
Guedez L, Rivera AM, Salloum R, Miller ML, Diegmueller JJ, Bungay PM, et al. Quantitative assessment of angiogenic responses by the directed in vivo angiogenesis assay. Am J Pathol 2003;162: 1431-9.
-
(2003)
Am J Pathol
, vol.162
, pp. 1431-1439
-
-
Guedez, L.1
Rivera, A.M.2
Salloum, R.3
Miller, M.L.4
Diegmueller, J.J.5
Bungay, P.M.6
-
33
-
-
80054778108
-
Targeted decorin gene therapy delivered with adeno-associated virus effectively retards corneal neovascularization in vivo
-
Mohan RR, Tovey JCK, Sharma A, Schultz GS, Cowden JW, Tandon A. Targeted decorin gene therapy delivered with adeno-associated virus effectively retards corneal neovascularization in vivo. PLoS One 2011;6:e26432.
-
(2011)
PLoS One
, vol.6
-
-
Mohan, R.R.1
Tovey, J.C.K.2
Sharma, A.3
Schultz, G.S.4
Cowden, J.W.5
Tandon, A.6
-
34
-
-
0034447622
-
Integrating the VEGF signals leading to actin-based motility in vascular endothelial cells
-
Rousseau S, Houle F, Huot J. Integrating the VEGF signals leading to actin-based motility in vascular endothelial cells. Trends Cardiovasc Med 2000;10: 321-7.
-
(2000)
Trends Cardiovasc Med
, vol.10
, pp. 321-327
-
-
Rousseau, S.1
Houle, F.2
Huot, J.3
-
35
-
-
33749028188
-
Vascular endothelial growth factor signaling pathways: Therapeutic perspective
-
Kowanetz M, Ferrara N. Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin Cancer Res 2006;12: 5018-22.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5018-5022
-
-
Kowanetz, M.1
Ferrara, N.2
-
36
-
-
34748863572
-
Mechanisms of integrin-vascular endothelial growth factor receptor crossactivation in angiogenesis
-
Mahabeleshwar GH, Feng W, Reddy K, Plow EF, Byzova TV. Mechanisms of integrin-vascular endothelial growth factor receptor crossactivation in angiogenesis. Circ Res 2007;10: 570-80.
-
(2007)
Circ Res
, vol.10
, pp. 570-580
-
-
Mahabeleshwar, G.H.1
Feng, W.2
Reddy, K.3
Plow, E.F.4
Byzova, T.V.5
-
37
-
-
0033558087
-
Role of avb3 integrin in the activation of vascular endothelial growth factor receptor-2
-
Soldi R, Mitola S, Strasly M, Defilippi P, Tarone G, Bussolino F. Role of avb3 integrin in the activation of vascular endothelial growth factor receptor-2. EMBO J 1999;18: 882-92.
-
(1999)
EMBO J
, vol.18
, pp. 882-892
-
-
Soldi, R.1
Mitola, S.2
Strasly, M.3
Defilippi, P.4
Tarone, G.5
Bussolino, F.6
-
38
-
-
0035895711
-
Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
-
Zachary I, Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc Res 2001;49: 568-81.
-
(2001)
Cardiovasc Res
, vol.49
, pp. 568-581
-
-
Zachary, I.1
Gliki, G.2
-
39
-
-
84869777262
-
Vasculogenic mimicry of HT1080 tumor cells in vivo: Critical role of HIF-1a-neuropilin-1 axis
-
Misra RM, Bajaj MS, Kale VP. Vasculogenic mimicry of HT1080 tumor cells in vivo: critical role of HIF-1a-neuropilin-1 axis. PLoS One 2012;7: e50153.
-
(2012)
PLoS One
, vol.7
-
-
Misra, R.M.1
Bajaj, M.S.2
Kale, V.P.3
-
40
-
-
63849278644
-
The urokinase receptor as an entertainer of signal transduction
-
D'Alessio S, Blasi F. The urokinase receptor as an entertainer of signal transduction. Front Biosci 2009;14: 4575-87.
-
(2009)
Front Biosci
, vol.14
, pp. 4575-4587
-
-
D'Alessio, S.1
Blasi, F.2
-
41
-
-
77951269420
-
Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: Ameta-analysis of randomized controlled trials
-
Ranpura V, Hapani S, Chuang J, Wu S. Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: ameta-analysis of randomized controlled trials. Acta Oncol 2010;49: 287-97.
-
(2010)
Acta Oncol
, vol.49
, pp. 287-297
-
-
Ranpura, V.1
Hapani, S.2
Chuang, J.3
Wu, S.4
-
42
-
-
68549085490
-
Branching morphogenesis and antiangiogenesis candidates: Tip cells lead the way
-
Carmeliet P, De Smet F, Loges S, Mazzone M. Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way. Nat Rev Clin Oncol 2009;6: 315-26.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 315-326
-
-
Carmeliet, P.1
De Smet, F.2
Loges, S.3
Mazzone, M.4
-
43
-
-
80051720462
-
The urokinase receptor system, a key regulator at the intersection between inflammation, immunity, and coagulation
-
Del Rosso M, Margheri F, Serratì S, Chillà A, Laurenzana A, Fibbi G. The urokinase receptor system, a key regulator at the intersection between inflammation, immunity, and coagulation. Curr Pharm Des 2011;17: 1924-43.
-
(2011)
Curr Pharm des
, vol.17
, pp. 1924-1943
-
-
Del Rosso, M.1
Margheri, F.2
Serratì, S.3
Chill̀a, A.4
Laurenzana, A.5
Fibbi, G.6
-
44
-
-
77953684206
-
Are formyl peptide receptors novel targets for therapeutic intervention in ischaemia-reperfusion injury?
-
Gavins FNE. Are formyl peptide receptors novel targets for therapeutic intervention in ischaemia-reperfusion injury? Trends Pharmacol Sci 2010;31 266-76.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 266-276
-
-
Gavins, F.N.E.1
-
45
-
-
80051691520
-
The urokinase-type plasminogen activator and the generation of inhibitors of urokinase activity and signalling
-
Carriero MV, Stoppelli MP. The urokinase-type plasminogen activator and the generation of inhibitors of urokinase activity and signalling. Curr Pharm Des 2011;17: 1944-61.
-
(2011)
Curr Pharm des
, vol.17
, pp. 1944-1961
-
-
Carriero, M.V.1
Stoppelli, M.P.2
|