Targeted decorin gene therapy delivered with adeno-associated virus effectively retards corneal neovascularization in vivo

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Mohan, Rajiv R ^a,b,c   Tovey, Jonathan C K ^a,b   Sharma, Ajay ^a,b   Schultz, Gregory S ^d   Cowden, John W ^b   Tandon, Ashish ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; COLLAGEN TYPE 4; DECORIN; EOSIN; HEMATOXYLIN; MESSENGER RNA; PARVOVIRUS VECTOR; VASCULOTROPIN; PRIMER DNA;

ADENO ASSOCIATED VIRUS; ANGIOPOIETIN GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CORNEA NEOVASCULARIZATION; DECORIN GENE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE TARGETING; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MCP1 GENE; MORPHOMETRICS; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PEDF GENE; QUANTITATIVE ANALYSIS; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; SLIT LAMP; STEREOMICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; VASCULAR ENDOTHELIUM DERIVED GROWTH FACTOR GENE; VIRAL GENE DELIVERY SYSTEM; ANIMAL; CORNEA; GENE THERAPY; GENETICS; NEOVASCULARIZATION (PATHOLOGY); NUCLEOTIDE SEQUENCE; VALIDATION STUDY; VASCULARIZATION; WESTERN BLOTTING;

ADENO-ASSOCIATED VIRUS; ANIMALIA; ORYCTOLAGUS CUNICULUS;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CORNEA; DECORIN; DEPENDOVIRUS; DNA PRIMERS; FEMALE; GENE TARGETING; GENE THERAPY; IMMUNOHISTOCHEMISTRY; NEOVASCULARIZATION, PATHOLOGIC; RABBITS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 80054778108     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026432     Document Type: Article

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