Centrosomal protein DZIP1 regulates hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis

Journal of Biological Chemistry

Volumn 288, Issue 41, 2013, Pages 29518-29529

  Wang, Chengbing ^a   Low, Wee Chuang ^a   Liu, Aimin ^b   Wang, Baolin ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DUAL MECHANISMS; HEDGEHOG SIGNALING; INTRAFLAGELLAR TRANSPORTS; MUTANT CELLS; PATHWAY COMPONENTS; PRIMARY CILIUM; TRANSCRIPTIONAL REGULATOR;

MACHINERY;

PROTEINS;

CELL PROTEIN; CENTROSOMAL PROTEIN DZIP1; PROTEIN CEP164; PROTEIN IFT88; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL LOSS; CELL MATURATION; CELL MUTANT; CELL NUCLEUS; CELLULAR DISTRIBUTION; CENTRIOLE; CILIARY MOTILITY; CILIOGENESIS; CONTROLLED STUDY; CYTOPLASM; EUKARYOTIC FLAGELLUM; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

CILIA; HEDGEHOG; PROTEIN-PROTEIN INTERACTIONS; SIGNALING; TRANSCRIPTION FACTORS;

ANIMALS; CELL LINE; CELLS, CULTURED; CENTRIOLES; CENTROSOME; CILIA; CYTOPLASM; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FIBROBLASTS; HEDGEHOG PROTEINS; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICROSCOPY, FLUORESCENCE; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEIN BINDING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84885633427     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.492066     Document Type: Article

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