A systems chemical biology study of malate synthase and isocitrate lyase inhibition in Mycobacterium tuberculosis during active and NRP growth

Computational Biology and Chemistry

Volumn 47, Issue , 2013, Pages 167-180

  May, Elebeoba E ^a   Leitão, Andrei ^b   Tropsha, Alexander ^c   Oprea, Tudor I ^d  

^a UNIVERSITY OF HOUSTON   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Biochemical network simulations; Biological networks; Cheminformatics; Mycobacterium tuberculosis; Systems biology Chemical biology

Indexed keywords

COMPUTER SIMULATION; METABOLISM; MOLECULES; OXYGEN;

BIOCHEMICAL NETWORK; BIOLOGICAL NETWORKS; CHEMICAL BIOLOGY; CHEMINFORMATICS; MYCOBACTERIUM TUBERCULOSIS;

CHEMICAL ANALYSIS;

BACILLI (CLASS); BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

ISOCITRATE LYASE; MALATE SYNTHASE; OXYGEN;

ARTICLE; BIOCHEMICAL NETWORK SIMULATIONS; BIOLOGICAL NETWORKS; CHEMICAL BIOLOGY; CHEMICAL STRUCTURE; CHEMINFORMATICS; DRUG ANTAGONISM; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; SYSTEMS BIOLOGY;

BIOCHEMICAL NETWORK SIMULATIONS; BIOLOGICAL NETWORKS; CHEMICAL BIOLOGY; CHEMINFORMATICS; MYCOBACTERIUM TUBERCULOSIS; SYSTEMS BIOLOGY;

ISOCITRATE LYASE; MALATE SYNTHASE; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; OXYGEN; SYSTEMS BIOLOGY;

EID: 84885615964     PISSN: 14769271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compbiolchem.2013.07.002     Document Type: Article

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