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Volumn 19, Issue 5, 2013, Pages 418-431

Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation

Author keywords

Adult neurogenesis; BDNF; Cdk5; Dendritic arborization; Exercise; HIV gp120

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIN DEPENDENT KINASE 5; GLYCOPROTEIN GP 120; VIRUS GLYCOPROTEIN;

EID: 84885613886     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-013-0194-6     Document Type: Article
Times cited : (43)

References (62)
  • 1
    • 35348892709 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons
    • 17928446 10.1523/JNEUROSCI.2733-07.2007 1:CAS:528:DC%2BD2sXht1Wnsb%2FI
    • Alirezaei M, Watry DD, Flynn CF, Kiosses WB, Masliah E, Williams BR, Kaul M, Lipton SA, Fox HS (2007) Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons. J Neurosci 27:11047-11055
    • (2007) J Neurosci , vol.27 , pp. 11047-11055
    • Alirezaei, M.1    Watry, D.D.2    Flynn, C.F.3    Kiosses, W.B.4    Masliah, E.5    Williams, B.R.6    Kaul, M.7    Lipton, S.A.8    Fox, H.S.9
  • 2
    • 80052669106 scopus 로고    scopus 로고
    • Neurodegenerative diseases: Exercising toward neurogenesis and neuroregeneration
    • doi: 10.3389/fnagi.2010.00025
    • Ang ET, Tai YK, Lo SQ, Seet R, Soong TW (2010) Neurodegenerative diseases: exercising toward neurogenesis and neuroregeneration. Front Aging Neurosci. doi: 10.3389/fnagi.2010.00025
    • (2010) Front Aging Neurosci
    • Ang, E.T.1    Tai, Y.K.2    Lo, S.Q.3    Seet, R.4    Soong, T.W.5
  • 3
    • 84863691365 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons
    • 22787033 10.1523/JNEUROSCI.0865-12.2012 1:CAS:528:DC%2BC38XhtVGlsb%2FI
    • Bachis A, Avdoshina V, Zecca L, Parsadanian M, Mocchetti I (2012) Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons. J Neurosci 32:9477-9484
    • (2012) J Neurosci , vol.32 , pp. 9477-9484
    • Bachis, A.1    Avdoshina, V.2    Zecca, L.3    Parsadanian, M.4    Mocchetti, I.5
  • 4
    • 84875262606 scopus 로고    scopus 로고
    • Exercise improves object recognition memory and induces BDNF expression and cell proliferation in cognitively enriched rats
    • 23439217 10.1016/j.bbr.2013.02.018 1:CAS:528:DC%2BC3sXltVSjtrY%3D
    • Bechara RG, Kelly AM (2013) Exercise improves object recognition memory and induces BDNF expression and cell proliferation in cognitively enriched rats. Behav Brain Res 245:96-100
    • (2013) Behav Brain Res , vol.245 , pp. 96-100
    • Bechara, R.G.1    Kelly, A.M.2
  • 5
    • 20444398484 scopus 로고    scopus 로고
    • Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
    • 15896913 10.1016/j.neuroscience.2005.03.026 1:CAS:528: DC%2BD2MXltFWisLo%3D
    • Berchtold NC, Chinn G, Chou M, Kesslak JP, Cotman CW (2005) Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus. Neuroscience 133:853-861
    • (2005) Neuroscience , vol.133 , pp. 853-861
    • Berchtold, N.C.1    Chinn, G.2    Chou, M.3    Kesslak, J.P.4    Cotman, C.W.5
  • 6
    • 57849162297 scopus 로고    scopus 로고
    • EdU, a new thymidine analogue for labelling proliferating cells in the nervous system
    • 18996411 10.1016/j.jneumeth.2008.10.006 1:CAS:528:DC%2BD1cXhsFCgsL%2FN
    • Chehrehasa F, Meedeniya AC, Dwyer P, Abrahamsen G, Mackay-Sim A (2009) EdU, a new thymidine analogue for labelling proliferating cells in the nervous system. J Neurosci Methods 177:122-130
    • (2009) J Neurosci Methods , vol.177 , pp. 122-130
    • Chehrehasa, F.1    Meedeniya, A.C.2    Dwyer, P.3    Abrahamsen, G.4    Mackay-Sim, A.5
  • 7
    • 34548496016 scopus 로고    scopus 로고
    • The roles of cyclin-dependent kinase 5 in dendrite and synapse development
    • 17526057 10.1002/biot.200700056 1:CAS:528:DC%2BD2sXpsFemsL8%3D
    • Cheung ZH, Ip NY (2007) The roles of cyclin-dependent kinase 5 in dendrite and synapse development. Biotechnol J 2:949-957
    • (2007) Biotechnol J , vol.2 , pp. 949-957
    • Cheung, Z.H.1    Ip, N.Y.2
  • 8
    • 45549108392 scopus 로고    scopus 로고
    • Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages
    • 18453587 1:CAS:528:DC%2BD1cXltlCktbk%3D
    • Cheung R, Ravyn V, Wang L, Ptasznik A, Collman RG (2008) Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages. J Immunol 180:6675-6684
    • (2008) J Immunol , vol.180 , pp. 6675-6684
    • Cheung, R.1    Ravyn, V.2    Wang, L.3    Ptasznik, A.4    Collman, R.G.5
  • 11
    • 0033455558 scopus 로고    scopus 로고
    • Age-related behavioural deficits in transgenic mice expressing the HIV-1 coat protein gp120
    • 10594667 10.1046/j.1460-9568.1999.00857.x
    • D'Hooge R, Franck F, Mucke L, De Deyn PP (1999) Age-related behavioural deficits in transgenic mice expressing the HIV-1 coat protein gp120. Eur J Neurosci 11:4398-4402
    • (1999) Eur J Neurosci , vol.11 , pp. 4398-4402
    • D'Hooge, R.1    Franck, F.2    Mucke, L.3    De Deyn, P.P.4
  • 13
    • 33845775666 scopus 로고    scopus 로고
    • HIV and antiretroviral therapy in the brain: Neuronal injury and repair
    • 17180161 10.1038/nrn2040 1:CAS:528:DC%2BD28XhtlemtL7O
    • Ellis R, Langford D, Masliah E (2007) HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci 8:33-44
    • (2007) Nat Rev Neurosci , vol.8 , pp. 33-44
    • Ellis, R.1    Langford, D.2    Masliah, E.3
  • 14
    • 31844447757 scopus 로고    scopus 로고
    • GABA regulates synaptic integration of newly generated neurons in the adult brain
    • 16341203 10.1038/nature04404 1:CAS:528:DC%2BD28XpsVCgsw%3D%3D
    • Ge S, Goh EL, Sailor KA, Kitabatake Y, Ming GL, Song H (2006) GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature 439:589-593
    • (2006) Nature , vol.439 , pp. 589-593
    • Ge, S.1    Goh, E.L.2    Sailor, K.A.3    Kitabatake, Y.4    Ming, G.L.5    Song, H.6
  • 17
    • 62849120358 scopus 로고    scopus 로고
    • GPI-1046 protects dorsal root ganglia from gp120-induced axonal injury by modulating store-operated calcium entry
    • 19335537 10.1111/j.1529-8027.2009.00203.x 1:CAS:528:DC%2BD1MXltVOguro%3D
    • Hoke A, Morris M, Haughey NJ (2009) GPI-1046 protects dorsal root ganglia from gp120-induced axonal injury by modulating store-operated calcium entry. J Peripher Nerv Syst 14:27-35
    • (2009) J Peripher Nerv Syst , vol.14 , pp. 27-35
    • Hoke, A.1    Morris, M.2    Haughey, N.J.3
  • 18
    • 80053093795 scopus 로고    scopus 로고
    • Physical exercise during adolescence versus adulthood: Differential effects on object recognition memory and brain-derived neurotrophic factor levels
    • 21839807 10.1016/j.neuroscience.2011.07.071 1:CAS:528:DC%2BC3MXht1eitrfM
    • Hopkins ME, Nitecki R, Bucci DJ (2011) Physical exercise during adolescence versus adulthood: differential effects on object recognition memory and brain-derived neurotrophic factor levels. Neuroscience 194:84-94
    • (2011) Neuroscience , vol.194 , pp. 84-94
    • Hopkins, M.E.1    Nitecki, R.2    Bucci, D.J.3
  • 19
    • 0037621531 scopus 로고    scopus 로고
    • Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant
    • 12759116 10.1016/S0091-3057(03)00044-3 1:CAS:528:DC%2BD3sXjvFanurg%3D
    • Ivy AS, Rodriguez FG, Garcia C, Chen MJ, Russo-Neustadt AA (2003) Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant. Pharmacol Biochem Behav 75:81-88
    • (2003) Pharmacol Biochem Behav , vol.75 , pp. 81-88
    • Ivy, A.S.1    Rodriguez, F.G.2    Garcia, C.3    Chen, M.J.4    Russo-Neustadt, A.A.5
  • 20
    • 33846217344 scopus 로고    scopus 로고
    • HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection
    • 16841089 10.1038/sj.cdd.4402006 1:CAS:528:DC%2BD2sXkslChtg%3D%3D
    • Kaul M, Ma Q, Medders KE, Desai MK, Lipton SA (2007) HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Cell Death Differ 14:296-305
    • (2007) Cell Death Differ , vol.14 , pp. 296-305
    • Kaul, M.1    Ma, Q.2    Medders, K.E.3    Desai, M.K.4    Lipton, S.A.5
  • 21
    • 84855166859 scopus 로고    scopus 로고
    • Running is the neurogenic and neurotrophic stimulus in environmental enrichment
    • 21878528 10.1101/lm.2283011 1:CAS:528:DC%2BC3MXht1ejtbvN
    • Kobilo T, Liu QR, Gandhi K, Mughal M, Shaham Y, van Praag H (2011) Running is the neurogenic and neurotrophic stimulus in environmental enrichment. Learn Mem 18:605-609
    • (2011) Learn Mem , vol.18 , pp. 605-609
    • Kobilo, T.1    Liu, Q.R.2    Gandhi, K.3    Mughal, M.4    Shaham, Y.5    Van Praag, H.6
  • 22
    • 33748188974 scopus 로고    scopus 로고
    • Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus
    • 16271278 10.1016/j.neurobiolaging.2005.09.016
    • Kronenberg G, Bick-Sander A, Bunk E, Wolf C, Ehninger D, Kempermann G (2006) Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus. Neurobiol Aging 27:1505-1513
    • (2006) Neurobiol Aging , vol.27 , pp. 1505-1513
    • Kronenberg, G.1    Bick-Sander, A.2    Bunk, E.3    Wolf, C.4    Ehninger, D.5    Kempermann, G.6
  • 23
    • 0032484546 scopus 로고    scopus 로고
    • Transgenic mice with cerebral expression of human immunodeficiency virus type-1 coat protein gp120 show divergent changes in short- and long-term potentiation in CA1 hippocampus
    • 9483553 10.1016/S0306-4522(97)00413-2 1:CAS:528:DyaK1cXmvVWgsw%3D%3D
    • Krucker T, Toggas SM, Mucke L, Siggins GR (1998) Transgenic mice with cerebral expression of human immunodeficiency virus type-1 coat protein gp120 show divergent changes in short- and long-term potentiation in CA1 hippocampus. Neuroscience 83:691-700
    • (1998) Neuroscience , vol.83 , pp. 691-700
    • Krucker, T.1    Toggas, S.M.2    Mucke, L.3    Siggins, G.R.4
  • 24
  • 26
    • 77955983504 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorder: Pathogenesis and therapeutic opportunities
    • 20396973 10.1007/s11481-010-9205-z
    • Lindl KA, Marks DR, Kolson DL, Jordan-Sciutto KL (2010) HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J Neuroimmune Pharmacol 5:294-309
    • (2010) J Neuroimmune Pharmacol , vol.5 , pp. 294-309
    • Lindl, K.A.1    Marks, D.R.2    Kolson, D.L.3    Jordan-Sciutto, K.L.4
  • 27
    • 33644507720 scopus 로고    scopus 로고
    • Adult neurogenesis and functional plasticity in neuronal circuits
    • 16495940 10.1038/nrn1867 1:CAS:528:DC%2BD28Xhs1Gqt78%3D
    • Lledo PM, Alonso M, Grubb MS (2006) Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci 7:179-193
    • (2006) Nat Rev Neurosci , vol.7 , pp. 179-193
    • Lledo, P.M.1    Alonso, M.2    Grubb, M.S.3
  • 28
    • 39849083186 scopus 로고    scopus 로고
    • BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?
    • 17942328 10.1016/j.nlm.2007.08.018 1:CAS:528:DC%2BD1cXjtVelt7c%3D
    • Lu Y, Christian K, Lu B (2008) BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiol Learn Mem 89:312-323
    • (2008) Neurobiol Learn Mem , vol.89 , pp. 312-323
    • Lu, Y.1    Christian, K.2    Lu, B.3
  • 30
    • 84860901234 scopus 로고    scopus 로고
    • Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice
    • 22252978 10.1002/dneu.22009 1:CAS:528:DC%2BC38XmvVKitL0%3D
    • Marlatt MW, Potter MC, Lucassen PJ, van Praag H (2012) Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice. Dev Neurobiol 72:943-952
    • (2012) Dev Neurobiol , vol.72 , pp. 943-952
    • Marlatt, M.W.1    Potter, M.C.2    Lucassen, P.J.3    Van Praag, H.4
  • 31
    • 84877303132 scopus 로고    scopus 로고
    • The effects of an aerobic and resistance exercise training program on cognition following stroke
    • Marzolini S, Oh P, McIlroy W, Brooks D (2013) The effects of an aerobic and resistance exercise training program on cognition following stroke. Neurorehabil Neural Repair 27(5):392-402
    • (2013) Neurorehabil Neural Repair , vol.27 , Issue.5 , pp. 392-402
    • Marzolini, S.1    Oh, P.2    McIlroy, W.3    Brooks, D.4
  • 32
    • 0036891081 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia
    • 12424697 10.1086/344528 1:CAS:528:DC%2BD38Xps1Krt74%3D
    • Nath A (2002) Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia. J Infect Dis 186(Suppl 2):S193-S198
    • (2002) J Infect Dis , vol.186 , Issue.SUPPL. 2
    • Nath, A.1
  • 33
    • 84875225131 scopus 로고    scopus 로고
    • Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway
    • 22886603 10.1007/s13365-012-0122-1 1:CAS:528:DC%2BC38XhslKnsbzL
    • Nath S, Bachani M, Harshavardhana D, Steiner JP (2012) Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway. J Neurovirol 18:445-455
    • (2012) J Neurovirol , vol.18 , pp. 445-455
    • Nath, S.1    Bachani, M.2    Harshavardhana, D.3    Steiner, J.P.4
  • 34
    • 0018777087 scopus 로고
    • Mechanism of propranolol withdrawal phenomena
    • 436208 10.1161/01.CIR.59.6.1158 1:STN:280:DyaE1M7mslyksw%3D%3D
    • Nattel S, Rangno RE, Van Loon G (1979) Mechanism of propranolol withdrawal phenomena. Circulation 59:1158-1164
    • (1979) Circulation , vol.59 , pp. 1158-1164
    • Nattel, S.1    Rangno, R.E.2    Van Loon, G.3
  • 35
    • 0010330438 scopus 로고    scopus 로고
    • Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain
    • 8836544 10.1016/0006-8993(96)00273-9 1:CAS:528:DyaK28XjvFGjtro%3D
    • Neeper SA, Gomez-Pinilla F, Choi J, Cotman CW (1996) Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res 726:49-56
    • (1996) Brain Res , vol.726 , pp. 49-56
    • Neeper, S.A.1    Gomez-Pinilla, F.2    Choi, J.3    Cotman, C.W.4
  • 36
    • 17744368458 scopus 로고    scopus 로고
    • Deregulation of Cdk5 in a mouse model of ALS: Toxicity alleviated by perikaryal neurofilament inclusions
    • 11343650 10.1016/S0896-6273(01)00268-9 1:CAS:528:DC%2BD3MXjsVCiu78%3D
    • Nguyen MD, Lariviere RC, Julien JP (2001) Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron 30:135-147
    • (2001) Neuron , vol.30 , pp. 135-147
    • Nguyen, M.D.1    Lariviere, R.C.2    Julien, J.P.3
  • 37
    • 10844234026 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 glycoprotein gp120 reduces the levels of brain-derived neurotrophic factor in vivo: Potential implication for neuronal cell death
    • 15579139 10.1111/j.1460-9568.2004.03764.x
    • Nosheny RL, Bachis A, Acquas E, Mocchetti I (2004) Human immunodeficiency virus type 1 glycoprotein gp120 reduces the levels of brain-derived neurotrophic factor in vivo: potential implication for neuronal cell death. Eur J Neurosci 20:2857-2864
    • (2004) Eur J Neurosci , vol.20 , pp. 2857-2864
    • Nosheny, R.L.1    Bachis, A.2    Acquas, E.3    Mocchetti, I.4
  • 38
    • 34547660197 scopus 로고    scopus 로고
    • HIV/gp120 decreases adult neural progenitor cell proliferation via checkpoint kinase-mediated cell-cycle withdrawal and G1 arrest
    • 18371353 10.1016/j.stem.2007.07.010 1:CAS:528:DC%2BD2sXhtVSnsrjP
    • Okamoto S, Kang YJ, Brechtel CW, Siviglia E, Russo R, Clemente A, Harrop A, McKercher S, Kaul M, Lipton SA (2007) HIV/gp120 decreases adult neural progenitor cell proliferation via checkpoint kinase-mediated cell-cycle withdrawal and G1 arrest. Cell Stem Cell 1:230-236
    • (2007) Cell Stem Cell , vol.1 , pp. 230-236
    • Okamoto, S.1    Kang, Y.J.2    Brechtel, C.W.3    Siviglia, E.4    Russo, R.5    Clemente, A.6    Harrop, A.7    McKercher, S.8    Kaul, M.9    Lipton, S.A.10
  • 39
    • 0033965158 scopus 로고    scopus 로고
    • The p38 signal transduction pathway: Activation and function
    • 10676842 10.1016/S0898-6568(99)00071-6 1:CAS:528:DC%2BD3cXot1en
    • Ono K, Han J (2000) The p38 signal transduction pathway: activation and function. Cell Signal 12:1-13
    • (2000) Cell Signal , vol.12 , pp. 1-13
    • Ono, K.1    Han, J.2
  • 40
    • 33646102681 scopus 로고    scopus 로고
    • Seizures accelerate functional integration of adult-generated granule cells
    • 16611826 10.1523/JNEUROSCI.5508-05.2006 1:CAS:528:DC%2BD28XktFantbk%3D
    • Overstreet-Wadiche LS, Bromberg DA, Bensen AL, Westbrook GL (2006) Seizures accelerate functional integration of adult-generated granule cells. J Neurosci 26:4095-4103
    • (2006) J Neurosci , vol.26 , pp. 4095-4103
    • Overstreet-Wadiche, L.S.1    Bromberg, D.A.2    Bensen, A.L.3    Westbrook, G.L.4
  • 41
    • 54049089271 scopus 로고    scopus 로고
    • Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: The role of p25/cyclin-dependent kinase 5
    • 18829967 10.1523/JNEUROSCI.3237-08.2008 1:CAS:528:DC%2BD1cXht1ChsLfN
    • Paoletti P, Vila I, Rife M, Lizcano JM, Alberch J, Gines S (2008) Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5. J Neurosci 28:10090-10101
    • (2008) J Neurosci , vol.28 , pp. 10090-10101
    • Paoletti, P.1    Vila, I.2    Rife, M.3    Lizcano, J.M.4    Alberch, J.5    Gines, S.6
  • 42
    • 79953666757 scopus 로고    scopus 로고
    • Increased CDK5 expression in HIV encephalitis contributes to neurodegeneration via tau phosphorylation and is reversed with Roscovitine
    • 21435449 10.1016/j.ajpath.2010.12.033 1:CAS:528:DC%2BC3MXmtVKgurw%3D
    • Patrick C, Crews L, Desplats P, Dumaop W, Rockenstein E, Achim CL, Everall IP, Masliah E (2011) Increased CDK5 expression in HIV encephalitis contributes to neurodegeneration via tau phosphorylation and is reversed with Roscovitine. Am J Pathol 178:1646-1661
    • (2011) Am J Pathol , vol.178 , pp. 1646-1661
    • Patrick, C.1    Crews, L.2    Desplats, P.3    Dumaop, W.4    Rockenstein, E.5    Achim, C.L.6    Everall, I.P.7    Masliah, E.8
  • 44
    • 79957628653 scopus 로고    scopus 로고
    • The timing for neuronal maturation in the adult hippocampus is modulated by local network activity
    • 21613484 10.1523/JNEUROSCI.1380-11.2011 1:CAS:528:DC%2BC3MXnt1Cgu7o%3D
    • Piatti VC, Davies-Sala MG, Esposito MS, Mongiat LA, Trinchero MF, Schinder AF (2011) The timing for neuronal maturation in the adult hippocampus is modulated by local network activity. J Neurosci 31:7715-7728
    • (2011) J Neurosci , vol.31 , pp. 7715-7728
    • Piatti, V.C.1    Davies-Sala, M.G.2    Esposito, M.S.3    Mongiat, L.A.4    Trinchero, M.F.5    Schinder, A.F.6
  • 45
    • 84874667522 scopus 로고    scopus 로고
    • Exercise improves behavioral, neurocognitive, and scholastic performance in children with attention-deficit/hyperactivity disorder
    • Pontifex MB, Saliba BJ, Raine LB, Picchietti DL, Hillman CH (2013) Exercise improves behavioral, neurocognitive, and scholastic performance in children with attention-deficit/hyperactivity disorder. J Pediatr 162(3):543-551
    • (2013) J Pediatr , vol.162 , Issue.3 , pp. 543-551
    • Pontifex, M.B.1    Saliba, B.J.2    Raine, L.B.3    Picchietti, D.L.4    Hillman, C.H.5
  • 46
    • 80051634663 scopus 로고    scopus 로고
    • Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats
    • 21846384 10.1186/1742-2094-8-101 1:CAS:528:DC%2BC3MXhtFyhsb3O
    • Rao JS, Kim HW, Kellom M, Greenstein D, Chen M, Kraft AD, Harry GJ, Rapoport SI, Basselin M (2011) Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats. J Neuroinflammation 8:101
    • (2011) J Neuroinflammation , vol.8 , pp. 101
    • Rao, J.S.1    Kim, H.W.2    Kellom, M.3    Greenstein, D.4    Chen, M.5    Kraft, A.D.6    Harry, G.J.7    Rapoport, S.I.8    Basselin, M.9
  • 49
    • 67949089966 scopus 로고    scopus 로고
    • The effects of exercise and stress on the survival and maturation of adult-generated granule cells
    • 19156854 10.1002/hipo.20552 1:CAS:528:DC%2BD1MXhtlyqsbfM
    • Snyder JS, Glover LR, Sanzone KM, Kamhi JF, Cameron HA (2009) The effects of exercise and stress on the survival and maturation of adult-generated granule cells. Hippocampus 19:898-906
    • (2009) Hippocampus , vol.19 , pp. 898-906
    • Snyder, J.S.1    Glover, L.R.2    Sanzone, K.M.3    Kamhi, J.F.4    Cameron, H.A.5
  • 50
    • 77956924897 scopus 로고    scopus 로고
    • Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice
    • 19070401 10.1016/j.neurobiolaging.2008.10.016 1:CAS:528: DC%2BC3cXht1WhtrbN
    • Stranahan AM, Lee K, Becker KG, Zhang Y, Maudsley S, Martin B, Cutler RG, Mattson MP (2010) Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice. Neurobiol Aging 31:1937-1949
    • (2010) Neurobiol Aging , vol.31 , pp. 1937-1949
    • Stranahan, A.M.1    Lee, K.2    Becker, K.G.3    Zhang, Y.4    Maudsley, S.5    Martin, B.6    Cutler, R.G.7    Mattson, M.P.8
  • 51
    • 0028009187 scopus 로고
    • Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice
    • 8114918 10.1038/367188a0 1:CAS:528:DyaK2cXhs1Sgtbc%3D
    • Toggas SM, Masliah E, Rockenstein EM, Rall GF, Abraham CR, Mucke L (1994) Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature 367:188-193
    • (1994) Nature , vol.367 , pp. 188-193
    • Toggas, S.M.1    Masliah, E.2    Rockenstein, E.M.3    Rall, G.F.4    Abraham, C.R.5    Mucke, L.6
  • 52
    • 0038042119 scopus 로고    scopus 로고
    • Chemokine receptors: Signposts to brain development and disease
    • 12778117 10.1038/nrn1116 1:CAS:528:DC%2BD3sXktFOgtLk%3D
    • Tran PB, Miller RJ (2003) Chemokine receptors: signposts to brain development and disease. Nat Rev Neurosci 4:444-455
    • (2003) Nat Rev Neurosci , vol.4 , pp. 444-455
    • Tran, P.B.1    Miller, R.J.2
  • 53
    • 0035875958 scopus 로고    scopus 로고
    • BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses
    • 11404410 1:CAS:528:DC%2BD3MXktlKls7k%3D
    • Tyler WJ, Pozzo-Miller LD (2001) BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. J Neurosci 21:4249-4258
    • (2001) J Neurosci , vol.21 , pp. 4249-4258
    • Tyler, W.J.1    Pozzo-Miller, L.D.2
  • 54
    • 0029892357 scopus 로고    scopus 로고
    • Inhibition of neuronal cyclin-dependent kinase-5 by staurosporine and purine analogs is independent of activation by Munc-18
    • 8726973 10.1007/BF02527763 1:CAS:528:DyaK28XjtVSgs7w%3D
    • Veeranna, Shetty KT, Amin N, Grant P, Albers RW, Pant HC (1996) Inhibition of neuronal cyclin-dependent kinase-5 by staurosporine and purine analogs is independent of activation by Munc-18. Neurochem Res 21:629-636
    • (1996) Neurochem Res , vol.21 , pp. 629-636
    • Veeranna1    Shetty, K.T.2    Amin, N.3    Grant, P.4    Albers, R.W.5    Pant, H.C.6
  • 55
    • 84891701025 scopus 로고    scopus 로고
    • All about running: Synaptic plasticity, growth factors and adult hippocampal neurogenesis
    • Vivar C, Potter MC, van Praag H (2013) All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis. Curr Top Behav Neurosci15:189-210
    • (2013) Curr Top Behav Neurosci , vol.15 , pp. 189-210
    • Vivar, C.1    Potter, M.C.2    Van Praag, H.3
  • 56
    • 34447544388 scopus 로고    scopus 로고
    • Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells
    • 17626215 10.1523/JNEUROSCI.0431-07.2007 1:CAS:528:DC%2BD2sXnvFyhu70%3D
    • Walter C, Murphy BL, Pun RY, Spieles-Engemann AL, Danzer SC (2007) Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells. J Neurosci 27:7541-7552
    • (2007) J Neurosci , vol.27 , pp. 7541-7552
    • Walter, C.1    Murphy, B.L.2    Pun, R.Y.3    Spieles-Engemann, A.L.4    Danzer, S.C.5
  • 57
    • 0141542665 scopus 로고    scopus 로고
    • Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
    • 14502288 10.1038/nn1119 1:CAS:528:DC%2BD3sXnsFamtbw%3D
    • Wang J, Liu S, Fu Y, Wang JH, Lu Y (2003) Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. Nat Neurosci 6:1039-1047
    • (2003) Nat Neurosci , vol.6 , pp. 1039-1047
    • Wang, J.1    Liu, S.2    Fu, Y.3    Wang, J.H.4    Lu, Y.5
  • 59
    • 57349113992 scopus 로고    scopus 로고
    • Exercise enhances the proliferation of neural stem cells and neurite growth and survival of neuronal progenitor cells in dentate gyrus of middle-aged mice
    • 18801961 10.1152/japplphysiol.90775.2008
    • Wu CW, Chang YT, Yu L, Chen HI, Jen CJ, Wu SY, Lo CP, Kuo YM (2008) Exercise enhances the proliferation of neural stem cells and neurite growth and survival of neuronal progenitor cells in dentate gyrus of middle-aged mice. J Appl Physiol 105:1585-1594
    • (2008) J Appl Physiol , vol.105 , pp. 1585-1594
    • Wu, C.W.1    Chang, Y.T.2    Yu, L.3    Chen, H.I.4    Jen, C.J.5    Wu, S.Y.6    Lo, C.P.7    Kuo, Y.M.8
  • 60
    • 84855644983 scopus 로고    scopus 로고
    • Sigma-1 receptor agonists provide neuroprotection against gp120 via a change in bcl-2 expression in mouse neuronal cultures
    • 22133307 10.1016/j.brainres.2011.10.053 1:CAS:528:DC%2BC3MXhs1Oqsb7N
    • Zhang Y, Shi Y, Qiao L, Sun Y, Ding W, Zhang H, Li N, Chen D (2012) Sigma-1 receptor agonists provide neuroprotection against gp120 via a change in bcl-2 expression in mouse neuronal cultures. Brain Res 1431:13-22
    • (2012) Brain Res , vol.1431 , pp. 13-22
    • Zhang, Y.1    Shi, Y.2    Qiao, L.3    Sun, Y.4    Ding, W.5    Zhang, H.6    Li, N.7    Chen, D.8
  • 61
    • 75849157143 scopus 로고    scopus 로고
    • PKCdelta regulates cortical radial migration by stabilizing the Cdk5 activator p35
    • 19965374 10.1073/pnas.0812872106 1:CAS:528:DC%2BC3cXjvFGltL4%3D
    • Zhao CT, Li K, Li JT, Zheng W, Liang XJ, Geng AQ, Li N, Yuan XB (2009) PKCdelta regulates cortical radial migration by stabilizing the Cdk5 activator p35. Proc Natl Acad Sci U S A 106:21353-21358
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 21353-21358
    • Zhao, C.T.1    Li, K.2    Li, J.T.3    Zheng, W.4    Liang, X.J.5    Geng, A.Q.6    Li, N.7    Yuan, X.B.8
  • 62
    • 77958594810 scopus 로고    scopus 로고
    • A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation
    • 20720012 10.1074/jbc.M110.134643 1:CAS:528:DC%2BC3cXhtlWktrbF
    • Zheng YL, Amin ND, Hu YF, Rudrabhatla P, Shukla V, Kanungo J, Kesavapany S, Grant P, Albers W, Pant HC (2010) A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation. J Biol Chem 285:34202-34212
    • (2010) J Biol Chem , vol.285 , pp. 34202-34212
    • Zheng, Y.L.1    Amin, N.D.2    Hu, Y.F.3    Rudrabhatla, P.4    Shukla, V.5    Kanungo, J.6    Kesavapany, S.7    Grant, P.8    Albers, W.9    Pant, H.C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.