Sigma-1 receptor agonists provide neuroprotection against gp120 via a change in bcl-2 expression in mouse neuronal cultures

Brain Research

Volumn 1431, Issue , 2012, Pages 13-22

  Zhang, Yulin ^a   Shi, Ying ^a   Qiao, Luxin ^b   Sun, Yu ^a   Ding, Wei ^b   Zhang, Honghai ^a   Li, Ning ^a   Chen, Dexi ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Dementia; Glycoprotein 120; Human immunodeficiency virus; Neuroprotection; Sigma receptors

Indexed keywords

4 PHENYL 1 (4 PHENYLBUTYL)PIPERIDINE; CALCEIN; GLYCOPROTEIN GP 120; LACTATE DEHYDROGENASE; MESSENGER RNA; NEUROPROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; RIMCAZOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; IMMUNOFLUORESCENCE; INCUBATION TIME; LACTATE DEHYDROGENASE BLOOD LEVEL; MORPHOMETRICS; MOUSE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN; CARBAZOLES; CELL SURVIVAL; CELLS, CULTURED; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; HALOPERIDOL; HIV ENVELOPE PROTEIN GP120; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; NEURITES; NEURONS; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, SIGMA; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84855644983     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.10.053     Document Type: Article

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