-
1
-
-
84878678105
-
Molecular events underlying Parkinson's disease: An interwoven tapestry
-
10.3389/fneur.2013.00033
-
Lim K. L., Zhang C. W., Molecular events underlying Parkinson's disease: an interwoven tapestry. Frontiers in Neurology 2013 4, article 33 10.3389/fneur.2013.00033
-
(2013)
Frontiers in Neurology
, vol.433
-
-
Lim, K.L.1
Zhang, C.W.2
-
2
-
-
84876832340
-
Target- and mechanism-based therapeutics for neurodegenerative diseases: Strength in numbers
-
Trippier P. C., Jansen Labby K., Hawker D. D., Mataka J. J., Silverman R. B., Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers. Journal of Medicinal Chemistry 2013 56 8 3121 3147
-
(2013)
Journal of Medicinal Chemistry
, vol.56
, Issue.8
, pp. 3121-3147
-
-
Trippier, P.C.1
Jansen Labby, K.2
Hawker, D.D.3
Mataka, J.J.4
Silverman, R.B.5
-
3
-
-
84883180845
-
Role of oxidative stress in Parkinson's disease
-
Hwang O., Role of oxidative stress in Parkinson's disease. Experimental Neurobiology 2013 22 1 11 17
-
(2013)
Experimental Neurobiology
, vol.22
, Issue.1
, pp. 11-17
-
-
Hwang, O.1
-
4
-
-
84884879594
-
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
-
10.1016/j.freeradbiomed.2012.11.014
-
Yan M. H., Wang X., Zhu X., Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease. Free Radical Biology and Medicine 2013 62 90 101 10.1016/j.freeradbiomed.2012.11.014
-
(2013)
Free Radical Biology and Medicine
, vol.62
, pp. 90-101
-
-
Yan, M.H.1
Wang, X.2
Zhu, X.3
-
5
-
-
79952229315
-
San-Huang-Xie-Xin-Tang protects against activated microglia- and 6-OHDA-induced toxicity in neuronal SH-SY5Y cells
-
2-s2.0-79952229315 10.1093/ecam/nep025 429384
-
Lo Y.-C., Shih Y.-T., Chen I.-J., Wu Y.-C., San-Huang-Xie-Xin-Tang protects against activated microglia- and 6-OHDA-induced toxicity in neuronal SH-SY5Y cells. Evidence-Based Complementary and Alternative Medicine 2011 2011 11 2-s2.0-79952229315 10.1093/ecam/nep025 429384
-
(2011)
Evidence-Based Complementary and Alternative Medicine
, vol.2011
, pp. 11
-
-
Lo, Y.-C.1
Shih, Y.-T.2
Chen, I.-J.3
Wu, Y.-C.4
-
6
-
-
84875454372
-
Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson's disease model
-
10.1155/2013/514095 514095
-
Kumar H., Kim I. S., More S. V., Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson's disease model. Evidence-Based Complementary and Alternative Medicine 2013 2013 13 10.1155/2013/514095 514095
-
(2013)
Evidence-Based Complementary and Alternative Medicine
, vol.2013
, pp. 13
-
-
Kumar, H.1
Kim, I.S.2
More, S.V.3
-
7
-
-
84862780536
-
Lonicera japonica THUNB. Protects 6-hydroxydopamine-induced neurotoxicity by inhibiting activation of MAPKs, PI3K/Akt, and NF- B in SH-SY5Y cells
-
2-s2.0-84856473411 10.1016/j.fct.2011.12.026
-
Kwon S.-H., Hong S.-I., Jung Y.-H., Kim M.-J., Kim S.-Y., Kim H.-C., Lee S.-Y., Jang C.-G., Lonicera japonica THUNB. protects 6-hydroxydopamine-induced neurotoxicity by inhibiting activation of MAPKs, PI3K/Akt, and NF- B in SH-SY5Y cells. Food and Chemical Toxicology 2012 50 3-4 797 807 2-s2.0-84856473411 10.1016/j.fct.2011.12.026
-
(2012)
Food and Chemical Toxicology
, vol.50
, Issue.3-4
, pp. 797-807
-
-
Kwon, S.-H.1
Hong, S.-I.2
Jung, Y.-H.3
Kim, M.-J.4
Kim, S.-Y.5
Kim, H.-C.6
Lee, S.-Y.7
Jang, C.-G.8
-
8
-
-
78651402013
-
Protective effect of panaxatriol saponins extracted from Panax notoginseng against MPTP-induced neurotoxicity in vivo
-
2-s2.0-78651402013 10.1016/j.jep.2010.10.017
-
Luo F.-C., Wang S.-D., Qi L., Song J.-Y., Lv T., Bai J., Protective effect of panaxatriol saponins extracted from Panax notoginseng against MPTP-induced neurotoxicity in vivo. Journal of Ethnopharmacology 2011 133 2 448 453 2-s2.0-78651402013 10.1016/j.jep.2010.10.017
-
(2011)
Journal of Ethnopharmacology
, vol.133
, Issue.2
, pp. 448-453
-
-
Luo, F.-C.1
Wang, S.-D.2
Qi, L.3
Song, J.-Y.4
Lv, T.5
Bai, J.6
-
9
-
-
70350062072
-
Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway
-
2-s2.0-70350062072 10.1111/j.1476-5381.2009.00361.x
-
Xu L., Chen W.-F., Wong M.-S., Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway. British Journal of Pharmacology 2009 158 3 738 748 2-s2.0-70350062072 10.1111/j.1476-5381.2009.00361.x
-
(2009)
British Journal of Pharmacology
, vol.158
, Issue.3
, pp. 738-748
-
-
Xu, L.1
Chen, W.-F.2
Wong, M.-S.3
-
10
-
-
84871748170
-
Rescue of PINK1 protein null-specific mitochondrial complex IV deficits by ginsenoside Re activation of nitric oxide signaling
-
Kim K. H., Song K., Yoon S. H., Rescue of PINK1 protein null-specific mitochondrial complex IV deficits by ginsenoside Re activation of nitric oxide signaling. Journal of Biological Chemistry 2012 287 53 44109 44120
-
(2012)
Journal of Biological Chemistry
, vol.287
, Issue.53
, pp. 44109-44120
-
-
Kim, K.H.1
Song, K.2
Yoon, S.H.3
-
11
-
-
7444270637
-
Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells
-
DOI 10.1016/j.neuro.2004.07.004, PII S0161813X04001007
-
Barlow B. K., Lee D. W., Cory-Slechta D. A., Opanashuk L. A., Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells. NeuroToxicology 2005 26 1 63 75 2-s2.0-7444270637 10.1016/j.neuro.2004.07.004 (Pubitemid 39440966)
-
(2005)
NeuroToxicology
, vol.26
, Issue.1
, pp. 63-75
-
-
Barlow, B.K.1
Lee, D.W.2
Cory-Slechta, D.A.3
Opanashuk, L.A.4
-
12
-
-
84878356929
-
Akt/Nrf2 activated upregulation of heme oxygenase-1 involves in the role of Rg1 against ferrous iron-induced neurotoxicity in SK-N-SH cells
-
Du X., Xu H., Jiang H., Xie J., Akt/Nrf2 activated upregulation of heme oxygenase-1 involves in the role of Rg1 against ferrous iron-induced neurotoxicity in SK-N-SH cells. Neurotoxicity Research 2013 24 1 71 79
-
(2013)
Neurotoxicity Research
, vol.24
, Issue.1
, pp. 71-79
-
-
Du, X.1
Xu, H.2
Jiang, H.3
Xie, J.4
-
13
-
-
78650995733
-
Characterization of ERK Docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9
-
2-s2.0-78650995733 10.1186/1471-2407-11-7
-
Boston S. R., Deshmukh R., Strome S., Priyakumar U. D., MacKerell A. D. Jr., Shapiro P., Characterization of ERK Docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9. BMC Cancer 2011 11, article 7 2-s2.0-78650995733 10.1186/1471-2407-11-7
-
(2011)
BMC Cancer
, vol.117
-
-
Boston, S.R.1
Deshmukh, R.2
Strome, S.3
Priyakumar, U.D.4
MacKerell Jr., A.D.5
Shapiro, P.6
-
14
-
-
79955364952
-
Treatment of a human papillomavirus type 31b-positive cell line with benzo[a]pyrene increases viral titer through activation of the Erk1/2 signaling pathway
-
2-s2.0-79955364952 10.1128/JVI.00133-11
-
Bowser B. S., Alam S., Meyers C., Treatment of a human papillomavirus type 31b-positive cell line with benzo[a]pyrene increases viral titer through activation of the Erk1/2 signaling pathway. Journal of Virology 2011 85 10 4982 4992 2-s2.0-79955364952 10.1128/JVI.00133-11
-
(2011)
Journal of Virology
, vol.85
, Issue.10
, pp. 4982-4992
-
-
Bowser, B.S.1
Alam, S.2
Meyers, C.3
-
15
-
-
84878725579
-
Decursin isolated from Angelica gigas Nakai rescues PC12 cells from amyloid beta-protein-induced neurotoxicity through Nrf2-mediated upregulation of Heme oxygenase-1: Potential roles of MAPK
-
467245 10.1155/2013/467245
-
Li L., Du J. K., Zou L. Y., Decursin isolated from Angelica gigas Nakai rescues PC12 cells from amyloid beta-protein-induced neurotoxicity through Nrf2-mediated upregulation of Heme oxygenase-1: potential roles of MAPK. Evidence-Based Complementary and Alternative Medicine 2013 2013 14 467245 10.1155/2013/467245
-
(2013)
Evidence-Based Complementary and Alternative Medicine
, vol.2013
, pp. 14
-
-
Li, L.1
Du, J.K.2
Zou, L.Y.3
-
16
-
-
84868451325
-
Oxidative stress suppression by luteolin-induced heme oxygenase-1 expression
-
Sun G. B., Sun X., Wang M., Oxidative stress suppression by luteolin-induced heme oxygenase-1 expression. Toxicology and Applied Pharmacology 2012 265 2 229 240
-
(2012)
Toxicology and Applied Pharmacology
, vol.265
, Issue.2
, pp. 229-240
-
-
Sun, G.B.1
Sun, X.2
Wang, M.3
-
17
-
-
84873715853
-
Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. Reduces inflammation in LPS-activated RAW 264. 7 cells and CLP-induced septic mice
-
Park E. J., Kim Y. M., Park S. W., Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. reduces inflammation in LPS-activated RAW 264. 7 cells and CLP-induced septic mice. Food and Chemical Toxicology 2013 55 386 395
-
(2013)
Food and Chemical Toxicology
, vol.55
, pp. 386-395
-
-
Park, E.J.1
Kim, Y.M.2
Park, S.W.3
-
18
-
-
80053643156
-
Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling
-
2-s2.0-80053643156 10.1016/j.neurobiolaging.2011.06.017
-
Xu J., Xilouri M., Bruban J., Shioi J., Shao Z., Papazoglou I., Vekrellis K., Robakis N. K., Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling. Neurobiology of Aging 2011 32 12 2326.e5 2326.e16 2-s2.0-80053643156 10.1016/j.neurobiolaging.2011.06.017
-
(2011)
Neurobiology of Aging
, vol.32
, Issue.12
-
-
Xu, J.1
Xilouri, M.2
Bruban, J.3
Shioi, J.4
Shao, Z.5
Papazoglou, I.6
Vekrellis, K.7
Robakis, N.K.8
-
19
-
-
77950267783
-
Hsp27 promotes insulin-like growth factor-I survival signaling in prostate cancer via p90Rsk-dependent phosphorylation and inactivation of BAD
-
2-s2.0-77950267783 10.1158/0008-5472.CAN-09-3252
-
Zoubeidi A., Zardan A., Wiedmann R. M., Locke J., Beraldi E., Fazli L., Gleave M. E., Hsp27 promotes insulin-like growth factor-I survival signaling in prostate cancer via p90Rsk-dependent phosphorylation and inactivation of BAD. Cancer Research 2010 70 6 2307 2317 2-s2.0-77950267783 10.1158/0008-5472.CAN-09- 3252
-
(2010)
Cancer Research
, vol.70
, Issue.6
, pp. 2307-2317
-
-
Zoubeidi, A.1
Zardan, A.2
Wiedmann, R.M.3
Locke, J.4
Beraldi, E.5
Fazli, L.6
Gleave, M.E.7
-
20
-
-
79959362322
-
ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation
-
2-s2.0-79959362322 10.1016/j.freeradbiomed.2011.04.019
-
Wang X., Liu J. Z., Hu J. X., Wu H., Li Y. L., Chen H. L., Bai H., Hai C. X., ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation. Free Radical Biology and Medicine 2011 51 2 539 551 2-s2.0-79959362322 10.1016/j.freeradbiomed.2011.04.019
-
(2011)
Free Radical Biology and Medicine
, vol.51
, Issue.2
, pp. 539-551
-
-
Wang, X.1
Liu, J.Z.2
Hu, J.X.3
Wu, H.4
Li, Y.L.5
Chen, H.L.6
Bai, H.7
Hai, C.X.8
-
21
-
-
84878552275
-
Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway
-
e64330
-
Yuan Y., Jiang C. Y., Xu H., Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway. PLoS ONE 2013 8 5 e64330
-
(2013)
PLoS ONE
, vol.8
, Issue.5
-
-
Yuan, Y.1
Jiang, C.Y.2
Xu, H.3
-
22
-
-
0027331917
-
The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls
-
DOI 10.1007/BF00978370
-
Andrew R., Watson D. G., Best S. A., Midgley J. M., Wenlong H., Petty R. K. H., The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls. Neurochemical Research 1993 18 11 1175 1177 2-s2.0-0027331917 10.1007/BF00978370 (Pubitemid 23306353)
-
(1993)
Neurochemical Research
, vol.18
, Issue.11
, pp. 1175-1177
-
-
Andrew, R.1
Watson, D.G.2
Best, S.A.3
Midgley, J.M.4
Wenlong, H.5
Petty, R.K.H.6
-
23
-
-
84872356254
-
Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo
-
Chambers J. W., Howard S., LoGrasso P. V., Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine- induced toxicity in vitro and in vivo. Journal of Biological Chemistry 2013 288 2 1079 1087
-
(2013)
Journal of Biological Chemistry
, vol.288
, Issue.2
, pp. 1079-1087
-
-
Chambers, J.W.1
Howard, S.2
Lograsso, P.V.3
-
24
-
-
33644657387
-
Dopamine transporter-mediated cytotoxicity of 6-hydroxydopamine in vitro depends on expression of mutant α-synucleins related to Parkinson's disease
-
DOI 10.1016/j.neuint.2005.11.008, PII S019701860500269X
-
Lehmensiek V., Tan E.-M., Liebau S., Lenk T., Zettlmeisl H., Schwarz J., Storch A., Dopamine transporter-mediated cytotoxicity of 6-hydroxydopamine in vitro depends on expression of mutant α -synucleins related to Parkinson's disease. Neurochemistry International 2006 48 5 329 340 2-s2.0-33644657387 10.1016/j.neuint.2005.11.008 (Pubitemid 43327272)
-
(2006)
Neurochemistry International
, vol.48
, Issue.5
, pp. 329-340
-
-
Lehmensiek, V.1
Tan, E.-M.2
Liebau, S.3
Lenk, T.4
Zettlmeisl, H.5
Schwarz, J.6
Storch, A.7
-
25
-
-
84872591393
-
6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-kappaB factors
-
Tobon-Velasco J. C., Limon-Pacheco J. H., Orozco-Ibarra M., 6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-kappaB factors. Toxicology 2013 304 109 119
-
(2013)
Toxicology
, vol.304
, pp. 109-119
-
-
Tobon-Velasco, J.C.1
Limon-Pacheco, J.H.2
Orozco-Ibarra, M.3
-
26
-
-
84884827950
-
Arylpiperazine-mediated activation of Akt protects SH-SY5Y neuroblastoma cells from 6-hydroxydopamine-induced apoptotic and autophagic death
-
Tovilovic G., Zogovic N., Soskic V., Arylpiperazine-mediated activation of Akt protects SH-SY5Y neuroblastoma cells from 6-hydroxydopamine-induced apoptotic and autophagic death. Neuropharmacology 2013 72 224 235
-
(2013)
Neuropharmacology
, vol.72
, pp. 224-235
-
-
Tovilovic, G.1
Zogovic, N.2
Soskic, V.3
-
27
-
-
80052689560
-
Cognitive-enhancing effect of quercetin in a rat model of Parkinson's disease induced by 6-hydroxydopamine
-
2-s2.0-80052689560 10.1155/2012/823206 823206
-
Sriraksa N., Wattanathorn J., Muchimapura S., Tiamkao S., Brown K., Chaisiwamongkol K., Cognitive-enhancing effect of quercetin in a rat model of Parkinson's disease induced by 6-hydroxydopamine. Evidence-Based Complementary and Alternative Medicine 2012 2012 9 2-s2.0-80052689560 10.1155/2012/823206 823206
-
(2012)
Evidence-Based Complementary and Alternative Medicine
, vol.2012
, pp. 9
-
-
Sriraksa, N.1
Wattanathorn, J.2
Muchimapura, S.3
Tiamkao, S.4
Brown, K.5
Chaisiwamongkol, K.6
-
28
-
-
84875600348
-
Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways
-
Cunha M. P., Martin-de-Saavedra M. D., Romero A., Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: involvement of intracellular signaling pathways. Neuroscience 2013 238 185 194
-
(2013)
Neuroscience
, vol.238
, pp. 185-194
-
-
Cunha, M.P.1
Martin-De-Saavedra, M.D.2
Romero, A.3
-
29
-
-
55949091956
-
15-Deoxy-Δ12,14-prostaglandin J2 rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: Potential roles of Akt and ERK1/2
-
2-s2.0-55949091956 10.1016/j.bcp.2008.08.007
-
Kim J.-W., Li M.-H., Jang J.-H., Na H.-K., Song N.-Y., Lee C., Johnson J. A., Surh Y.-J., 15-Deoxy-Δ12,14-prostaglandin J2 rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2. Biochemical Pharmacology 2008 76 11 1577 1589 2-s2.0-55949091956 10.1016/j.bcp.2008.08.007
-
(2008)
Biochemical Pharmacology
, vol.76
, Issue.11
, pp. 1577-1589
-
-
Kim, J.-W.1
Li, M.-H.2
Jang, J.-H.3
Na, H.-K.4
Song, N.-Y.5
Lee, C.6
Johnson, J.A.7
Surh, Y.-J.8
-
30
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-x(L), and Bcl-2, displaces Bax and promotes cell death
-
2-s2.0-0028809209
-
Yang E., Zha J., Jockel J., Boise L. H., Thompson C. B., Korsmeyer S. J., Bad, a heterodimeric partner for Bcl-x(L), and Bcl-2, displaces Bax and promotes cell death. Cell 1995 80 2 285 291 2-s2.0-0028809209
-
(1995)
Cell
, vol.80
, Issue.2
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
31
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
DOI 10.1126/science.286.5443.1358
-
Bonni A., Brunet A., West A. E., Datta S. R., Takasu M. A., Greenberg M. E., Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 1999 286 5443 1358 1362 2-s2.0-0032698075 10.1126/science.286.5443.1358 (Pubitemid 29535895)
-
(1999)
Science
, vol.286
, Issue.5443
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
32
-
-
41849088475
-
The roles of MAPKs in disease
-
DOI 10.1038/cr.2008.37, PII CR200837
-
Lawrence M. C., Jivan A., Shao C., Duan L., Goad D., Zaganjor E., Osborne J., McGlynn K., Stippec S., Earnest S., Chen W., Cobb M. H., The roles of MAPKs in disease. Cell Research 2008 18 4 436 442 2-s2.0-41849088475 10.1038/cr.2008.37 (Pubitemid 351498850)
-
(2008)
Cell Research
, vol.18
, Issue.4
, pp. 436-442
-
-
Lawrence, M.C.1
Jivan, A.2
Shao, C.3
Duan, L.4
Goad, D.5
Zaganjor, E.6
Osborne, J.7
McGlynn, K.8
Stippec, S.9
Earnest, S.10
Chen, W.11
Cobb, M.H.12
|