Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus)

British Journal of Pharmacology

Volumn 170, Issue 5, 2013, Pages 1130-1136

  O'Brien, L D ^a   Limebeer, C L ^a   Rock, E M ^a   Bottegoni, G ^b   Piomelli, D ^b,c   Parker, Linda A ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

anandamide; ARN272; CB1; endocannabinoid; FAAH 1 like anandamide transporter; FLAT; gaping; nausea; taste reactivity; vomiting

Indexed keywords

[4 [5 (4 HYDROXYPHENYL) 3,4 DIAZABICYCLO[4.4.0]DECA 1(6),2,4,7,9 PENTAEN 2 YLAMINO]PHENYL]PHENYLAMINOMETHANONE; ANANDAMIDE; ANTIEMETIC AGENT; CANNABINOID 1 RECEPTOR; LITHIUM CHLORIDE; RIMONABANT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIEMETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; MALE; NAUSEA; NONHUMAN; PRIORITY JOURNAL; RAT; SHREW; SUNCUS MURINUS; VOMITING;

ANANDAMIDE; ARN272; CB1; ENDOCANNABINOID; FAAH-1-LIKE ANANDAMIDE TRANSPORTER; FLAT; GAPING; NAUSEA; TASTE REACTIVITY; VOMITING;

AMIDOHYDROLASES; ANIMALS; ANTIEMETICS; ARACHIDONIC ACIDS; BEHAVIOR, ANIMAL; BIOLOGICAL TRANSPORT; CANNABINOID RECEPTOR ANTAGONISTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCANNABINOIDS; ISOENZYMES; LITHIUM CHLORIDE; MALE; NAUSEA; PIPERIDINES; POLYUNSATURATED ALKAMIDES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; SHREWS; VOMITING;

EID: 84885574145     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12360     Document Type: Article

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