Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors

Molecular Neurodegeneration

Volumn 8, Issue 1, 2013, Pages

  Veeraraghavalu, Karthikeyan ^a   Choi, Se Hoon ^a   Zhang, Xiaoqiong ^a   Sisodia, Sangram S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Adult neurogenesis; Alzheimer's disease; Presenilin mutants

Indexed keywords

PRESENILIN 1;

ADULT HIPPOCAMPAL NEURAL PROGENITOR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENVIRONMENTAL ENRICHMENT; GENE MUTATION; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; STEM CELL;

MUS; MUS MUSCULUS;

ADULT STEM CELLS; AGING; ALZHEIMER DISEASE; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; GENE KNOCK-IN TECHNIQUES; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL STEM CELLS; NEUROGENESIS; PRESENILIN-1;

EID: 84885539452     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-8-41     Document Type: Article

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