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Volumn 91, Issue 11, 2013, Pages 951-959

Quercetin provides greater cardioprotective effect than its glycoside derivative rutin on isoproterenol-induced cardiac fibrosis in the rat

Author keywords

Cardiac fibrosis; CTGF; ECM; Quercetin; Rutin; TGF 1

Indexed keywords

ANGIOTENSIN II; CONNECTIVE TISSUE GROWTH FACTOR; GLYCOSIDE; ISOPRENALINE; QUERCETIN; RUTOSIDE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84885455893     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2012-0432     Document Type: Article
Times cited : (66)

References (37)
  • 1
    • 71949108802 scopus 로고    scopus 로고
    • Preventive effect of amiodarone during acute period in isoproterenolinduced myocardial injury in Wistar rats
    • doi:10.1007/s12012-009-9049-z. PMID:19714493
    • Albayrak, F., Bayir, Y., Halici, Z., Kabalar, E., Bayram, E., Ozturk, C., et al. 2009. Preventive effect of amiodarone during acute period in isoproterenolinduced myocardial injury in Wistar rats. Cardiovasc. Toxicol. 9(4): 161-168. doi:10.1007/s12012-009-9049-z. PMID:19714493.
    • (2009) Cardiovasc. Toxicol. , vol.9 , Issue.4 , pp. 161-168
    • Albayrak, F.1    Bayir, Y.2    Halici, Z.3    Kabalar, E.4    Bayram, E.5    Ozturk, C.6
  • 2
    • 4243637176 scopus 로고    scopus 로고
    • Ischemic cardiomyopathy and the cellular renin-angiotensin system
    • doi:10.1016/S1053-2498(99)00111-4. PMID: 11016481
    • Anversa, P., Leri, A., Li, B., Liu, Y., Di Somma, S., and Kajstura, J. 2000. Ischemic cardiomyopathy and the cellular renin-angiotensin system. J. Heart Lung Transplant. 19(8 Suppl.): S1-S11. doi:10.1016/S1053-2498(99)00111-4. PMID: 11016481.
    • (2000) J. Heart Lung Transplant. , vol.19 , Issue.8 SUPPL.
    • Anversa, P.1    Leri, A.2    Li, B.3    Liu, Y.4    Di Somma, S.5    Kajstura, J.6
  • 3
    • 43049176634 scopus 로고    scopus 로고
    • Health effects of quercetin: From antioxidant to nutraceutical
    • doi:10.1016/j.ejphar.2008.03.008. PMID:18417116
    • Boots, A.W., Haenen, G.R., and Bast, A. 2008. Health effects of quercetin: from antioxidant to nutraceutical. Eur. J. Pharmacol. 585(2-3): 325-337. doi:10.1016/j.ejphar.2008.03.008. PMID:18417116.
    • (2008) Eur. J. Pharmacol. , vol.585 , Issue.2-3 , pp. 325-337
    • Boots, A.W.1    Haenen, G.R.2    Bast, A.3
  • 4
    • 0028793752 scopus 로고
    • Molecular signalling mechanisms controlling growth and function of cardiac fibroblasts
    • doi:10.1016/S0008-6363(96)88507-5. PMID:8575002
    • Booz, G.W., and Baker, K.M. 1995. Molecular signalling mechanisms controlling growth and function of cardiac fibroblasts. Cardiovasc. Res. 30(4): 537-543. doi:10.1016/S0008-6363(96)88507-5. PMID:8575002.
    • (1995) Cardiovasc. Res. , vol.30 , Issue.4 , pp. 537-543
    • Booz, G.W.1    Baker, K.M.2
  • 5
    • 0028275578 scopus 로고
    • Collagen metabolism in cultured adult rat cardiac fibroblasts: Response to angiotensin II and aldosterone
    • doi:10.1006/jmcc.1994.1098. PMID:7966349
    • Brilla, C.G., Zhou, G., Matsubara, L., and Weber, K.T. 1994. Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone. J. Mol. Cell. Cardiol. 26(7): 809-820. doi:10.1006/jmcc.1994.1098. PMID:7966349.
    • (1994) J. Mol. Cell. Cardiol. , vol.26 , Issue.7 , pp. 809-820
    • Brilla, C.G.1    Zhou, G.2    Matsubara, L.3    Weber, K.T.4
  • 6
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • doi:10.1016/0167-5699(94)90018-3. PMID: 8136014
    • Buttke, T.M., and Sandstrom, P.A. 1994. Oxidative stress as a mediator of apoptosis. Immunol. Today, 15(1): 7. doi:10.1016/0167-5699(94)90018-3. PMID: 8136014.
    • (1994) Immunol. Today , vol.15 , Issue.1 , pp. 7
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 7
    • 33645816102 scopus 로고    scopus 로고
    • Cardioprotective effects of eplerenone in the rat heart: Interaction with locally synthesized or blood-derived aldosterone?
    • doi:10.1161/01.HYP. 0000205831.39339.a5. PMID:16490840
    • Chai, W., Garrelds, I.M., de Vries, R., and Danser, A.H. 2006a. Cardioprotective effects of eplerenone in the rat heart: interaction with locally synthesized or blood-derived aldosterone? Hypertension, 47(4): 665-670. doi:10.1161/01.HYP. 0000205831.39339.a5. PMID:16490840.
    • (2006) Hypertension , vol.47 , Issue.4 , pp. 665-670
    • Chai, W.1    Garrelds, I.M.2    de Vries, R.3    Danser, A.H.4
  • 9
    • 0033745462 scopus 로고    scopus 로고
    • CTGF Expression is Induced by TGF-β in cardiac fibroblasts and cardiac myocytes: A potential role in heart fibrosis
    • doi:10. 1006/jmcc.2000.1215. PMID:11013125
    • Chen, M.M., Lam, A., Abraham, J.A., Schreiner, G.F., and Joly, A.H. 2000. CTGF Expression is Induced by TGF-β in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis. J. Mol. Cell. Cardiol. 32(10): 1805-1819. doi:10. 1006/jmcc.2000.1215. PMID:11013125.
    • (2000) J. Mol. Cell. Cardiol. , vol.32 , Issue.10 , pp. 1805-1819
    • Chen, M.M.1    Lam, A.2    Abraham, J.A.3    Schreiner, G.F.4    Joly, A.H.5
  • 10
    • 20344382953 scopus 로고    scopus 로고
    • 2-induced apoptosis via antioxidant activity and heme oxygenase 1 gene expression in macrophages
    • doi:10.1016/j.bcp.2005.03.017. PMID: 15876423
    • 2-induced apoptosis via antioxidant activity and heme oxygenase 1 gene expression in macrophages. Biochem. Pharmacol. 69(12): 1839. doi:10.1016/j.bcp.2005.03.017. PMID: 15876423.
    • (2005) Biochem. Pharmacol. , vol.69 , Issue.12 , pp. 1839
    • Chow, J.M.1    Shen, S.C.2    Huan, S.K.3    Lin, H.Y.4    Chen, Y.C.5
  • 11
    • 0033428596 scopus 로고    scopus 로고
    • Connective tissue growth factor: A potential stimulus for glomerulosclerosis and tubulointerstitial fibrosis in progressive renal disease
    • doi:10.1097/00041552-199909000-00002. PMID:10541215
    • Clarkson, M.R., Gupta, S., Murphy, M., Martin, F., Godson, C., and Brady, H.R. 1999. Connective tissue growth factor: a potential stimulus for glomerulosclerosis and tubulointerstitial fibrosis in progressive renal disease. Curr. Opin. Nephrol. Hypertens. 8(5): 543-548. doi:10.1097/00041552-199909000-00002. PMID:10541215.
    • (1999) Curr. Opin. Nephrol. Hypertens. , vol.8 , Issue.5 , pp. 543-548
    • Clarkson, M.R.1    Gupta, S.2    Murphy, M.3    Martin, F.4    Godson, C.5    Brady, H.R.6
  • 12
    • 0037196147 scopus 로고    scopus 로고
    • Quercetin, but not its glycosides, is absorbed from the rat stomach
    • doi:10.1021/jf010919h. PMID:11804539
    • Crespy, V., Morand, C., Besson, C., Manach, C., Demigne, C., and Remesy, C. 2002. Quercetin, but not its glycosides, is absorbed from the rat stomach. J. Agr. Food Chem. 50(3): 618-621. doi:10.1021/jf010919h. PMID:11804539.
    • (2002) J. Agr. Food Chem. , vol.50 , Issue.3 , pp. 618-621
    • Crespy, V.1    Morand, C.2    Besson, C.3    Manach, C.4    Demigne, C.5    Remesy, C.6
  • 13
    • 0037409309 scopus 로고    scopus 로고
    • Local renin-angiotensin systems: The unanswered questions
    • doi:10.1016/S1357-2725(02)00178-4. PMID:12676161
    • Danser, A.H. 2003. Local renin-angiotensin systems: the unanswered questions. Int. J. Biochem. Cell Biol. 35(6): 759-768. doi:10.1016/S1357-2725(02)00178-4. PMID:12676161.
    • (2003) Int. J. Biochem. Cell Biol. , vol.35 , Issue.6 , pp. 759-768
    • Danser, A.H.1
  • 14
    • 77953435948 scopus 로고    scopus 로고
    • Establishment of rat model of large dose isoproternol-induced myocardial ischemic necrosis [J]
    • 028
    • Gao, H., Sun, B., and Miao, C. 2009. Establishment of rat model of large dose isoproternol-induced myocardial ischemic necrosis [J]. Chinese Journal of Biologicals, 3: 028.
    • (2009) Chinese Journal of Biologicals , vol.3
    • Gao, H.1    Sun, B.2    Miao, C.3
  • 15
    • 35348985931 scopus 로고    scopus 로고
    • Inhibition of renin-angiotensin system and advanced glycation end products formation: A promising therapeutic approach targeting on cardiovascular diseases
    • doi:10.2174/187152507782109926. PMID:17979687
    • Geronikaki, A., Gavalas, A., Dislian, V., and Giannoglou, G. 2007. Inhibition of renin-angiotensin system and advanced glycation end products formation: a promising therapeutic approach targeting on cardiovascular diseases. Cardiovasc. Hematol. Agents Med. Chem. 5(4): 249-264. doi:10.2174/187152507782109926. PMID:17979687.
    • (2007) Cardiovasc. Hematol. Agents Med. Chem. , vol.5 , Issue.4 , pp. 249-264
    • Geronikaki, A.1    Gavalas, A.2    Dislian, V.3    Giannoglou, G.4
  • 16
    • 0031225015 scopus 로고    scopus 로고
    • Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
    • doi:10.1016/S1359-6101(97)00010-5. PMID:9462483
    • Grotendorst, G.R. 1997. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev. 8(3): 171. doi:10.1016/S1359-6101(97)00010-5. PMID:9462483.
    • (1997) Cytokine Growth Factor Rev. , vol.8 , Issue.3 , pp. 171
    • Grotendorst, G.R.1
  • 17
    • 0032819772 scopus 로고    scopus 로고
    • Dietary flavonoids: Intake, health effects and bioavailability
    • doi:10.1016/S0278-6915 (99)00079-4. PMID:10541448
    • Hollman, P., and Katan, M. 1999. Dietary flavonoids: intake, health effects and bioavailability. Food Chem. Toxicol. 37(9-10): 937. doi:10.1016/S0278-6915 (99)00079-4. PMID:10541448.
    • (1999) Food Chem. Toxicol. , vol.37 , Issue.9-10 , pp. 937
    • Hollman, P.1    Katan, M.2
  • 18
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • doi:10.1038/sj.ki.5000011. PMID: 16374430
    • Huang, Y., Wongamorntham, S., Kasting, J., McQuillan, D., Owens, R.T., Yu, L., et al. 2006. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int. 69(1): 105-113. doi:10.1038/sj.ki.5000011. PMID: 16374430.
    • (2006) Kidney Int. , vol.69 , Issue.1 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3    McQuillan, D.4    Owens, R.T.5    Yu, L.6
  • 19
    • 0031959237 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor in human renal fibrosis
    • doi:10.1111/j.1523-1755.1998.00820.x. PMID:9551391
    • Ito, Y., Aten, J., Bende, R.J., Oemar, B.S., Rabelink, T.J., Weening, J.J., et al. 1998. Expression of connective tissue growth factor in human renal fibrosis. Kidney Int. 53(4): 853-861. doi:10.1111/j.1523-1755.1998.00820.x. PMID:9551391.
    • (1998) Kidney Int. , vol.53 , Issue.4 , pp. 853-861
    • Ito, Y.1    Aten, J.2    Bende, R.J.3    Oemar, B.S.4    Rabelink, T.J.5    Weening, J.J.6
  • 20
    • 0025697262 scopus 로고
    • Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury
    • doi:10.1016/0891-5849(90)90131-2. PMID:2079232
    • Janero, D.R. 1990. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic. Biol. Med. 9(6): 515-540. doi:10.1016/0891-5849(90)90131-2. PMID:2079232.
    • (1990) Free Radic. Biol. Med. , vol.9 , Issue.6 , pp. 515-540
    • Janero, D.R.1
  • 21
    • 80052273994 scopus 로고    scopus 로고
    • Anti-inflammatory, anti-proliferative and antiatherosclerotic effects of quercetin in human in vitro and in vivo models
    • doi:10.1016/j.atherosclerosis.2011.04.023. PMID:21601209
    • Kleemann, R., Verschuren, L., Morrison, M., Zadelaar, S., van Erk, M.J., Wielinga, P.Y., et al. 2011. Anti-inflammatory, anti-proliferative and antiatherosclerotic effects of quercetin in human in vitro and in vivo models. Atherosclerosis, 218(1): 44-52. doi:10.1016/j.atherosclerosis.2011.04.023. PMID:21601209.
    • (2011) Atherosclerosis , vol.218 , Issue.1 , pp. 44-52
    • Kleemann, R.1    Verschuren, L.2    Morrison, M.3    Zadelaar, S.4    van Erk, M.J.5    Wielinga, P.Y.6
  • 22
    • 74149085153 scopus 로고    scopus 로고
    • Oxidative stress and glutathione in TGF-β-mediated fibrogenesis
    • doi:10.1016/j. freeradbiomed.2009.09.026. PMID:19800967
    • Liu, R.M., and Gaston Pravia, K. 2010. Oxidative stress and glutathione in TGF-β-mediated fibrogenesis. Free Radic. Biol. Med. 48(1): 1-15. doi:10.1016/j. freeradbiomed.2009.09.026. PMID:19800967.
    • (2010) Free Radic. Biol. Med. , vol.48 , Issue.1 , pp. 1-15
    • Liu, R.M.1    Gaston Pravia, K.2
  • 23
    • 0034491103 scopus 로고    scopus 로고
    • Quercetin 3-O-betaglucoside is better absorbed than other quercetin forms and is not present in rat plasma
    • doi:10.1080/10715760000301181. PMID:11200097
    • Morand, C., Manach, C., Crespy, V., and Remesy, C. 2000. Quercetin 3-O-betaglucoside is better absorbed than other quercetin forms and is not present in rat plasma. Free Radic. Res. 33(5): 667-676. doi:10.1080/10715760000301181. PMID:11200097.
    • (2000) Free Radic. Res. , vol.33 , Issue.5 , pp. 667-676
    • Morand, C.1    Manach, C.2    Crespy, V.3    Remesy, C.4
  • 24
    • 1842421154 scopus 로고    scopus 로고
    • Molecular imaging of the biological effects of quercetin and quercetin-rich foods
    • doi:10.1016/j.mad.2004.01.007. PMID:15063108
    • Moskaug, J.O., Carlsen, H., Myhrstad, M., and Blomhoff, R. 2004. Molecular imaging of the biological effects of quercetin and quercetin-rich foods. Mech. Ageing Dev. 125(4): 315-324. doi:10.1016/j.mad.2004.01.007. PMID:15063108.
    • (2004) Mech. Ageing Dev. , vol.125 , Issue.4 , pp. 315-324
    • Moskaug, J.O.1    Carlsen, H.2    Myhrstad, M.3    Blomhoff, R.4
  • 25
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • doi:10.1172/JCI200214276. PMID:12045255
    • Nguyen, G., Delarue, F., Burckle, C., Bouzhir, L., Giller, T., and Sraer, J.D. 2002. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J. Clin. Invest. 109(11): 1417-1427. doi:10.1172/JCI200214276. PMID:12045255.
    • (2002) J. Clin. Invest. , vol.109 , Issue.11 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 26
    • 0030002254 scopus 로고    scopus 로고
    • Protective role of curcumin against isoproterenol induced myocardial infarction in rats
    • doi:10.1007/BF00420910. PMID:8858558
    • Nirmala, C., and Puvanakrishnan, R. 1996. Protective role of curcumin against isoproterenol induced myocardial infarction in rats. Mol. Cell. Biochem. 159(2): 85-93. doi:10.1007/BF00420910. PMID:8858558.
    • (1996) Mol. Cell. Biochem. , vol.159 , Issue.2 , pp. 85-93
    • Nirmala, C.1    Puvanakrishnan, R.2
  • 27
    • 0032862910 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor in experimental rat and human liver fibrosis
    • doi:10.1002/hep.510300425. PMID:10498649
    • Paradis, V., Dargere, D., Vidaud, M., de Gouville, A.C., Huet, S., Martinez, V., et al. 2003. Expression of connective tissue growth factor in experimental rat and human liver fibrosis. Hepatology, 30(4): 968-976. doi:10.1002/hep.510300425. PMID:10498649.
    • (2003) Hepatology , vol.30 , Issue.4 , pp. 968-976
    • Paradis, V.1    Dargere, D.2    Vidaud, M.3    de Gouville, A.C.4    Huet, S.5    Martinez, V.6
  • 28
    • 0142039144 scopus 로고    scopus 로고
    • The study of the quercetin action on human erythrocyte membranes
    • doi:10.1016/S0006-2952(03)00344-7. PMID:12906925
    • Pawlikowska-Pawlega, B., Gruszecki, W.I., Misiak, L.E., and Gawron, A. 2003. The study of the quercetin action on human erythrocyte membranes. Biochem. Pharmacol. 66(4): 605-612. doi:10.1016/S0006-2952(03)00344-7. PMID:12906925.
    • (2003) Biochem. Pharmacol. , vol.66 , Issue.4 , pp. 605-612
    • Pawlikowska-Pawlega, B.1    Gruszecki, W.I.2    Misiak, L.E.3    Gawron, A.4
  • 29
    • 67249152096 scopus 로고    scopus 로고
    • Cardiac fibroblasts: At the heart of myocardial remodeling
    • doi:10.1016/j.pharmthera. 2009.05.002. PMID:19460403
    • Porter, K.E., and Turner, N.A. 2009. Cardiac fibroblasts: At the heart of myocardial remodeling. Pharmacol. Ther. 123(2): 255-278. doi:10.1016/j.pharmthera. 2009.05.002. PMID:19460403.
    • (2009) Pharmacol. Ther. , vol.123 , Issue.2 , pp. 255-278
    • Porter, K.E.1    Turner, N.A.2
  • 30
    • 84961042096 scopus 로고
    • An infarct-like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat
    • PMID:13636626
    • Rona, G., Chappel, C.I., Balazs, T., and Gaudry, R. 1959. An infarct-like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat. AMA Arch. Pathol. 67(4): 443-455. PMID:13636626.
    • (1959) AMA Arch. Pathol. , vol.67 , Issue.4 , pp. 443-455
    • Rona, G.1    Chappel, C.I.2    Balazs, T.3    Gaudry, R.4
  • 31
    • 0036545584 scopus 로고    scopus 로고
    • Role of oxidative stress in myocardial hypertrophy and failure
    • doi:10.1006/jmcc.2002.1526. PMID:11991728
    • Sawyer, D.B., Siwik, D.A., Xiao, L., Pimentel, D.R., Singh, K., and Colucci, W.S. 2002. Role of oxidative stress in myocardial hypertrophy and failure. J. Mol. Cell. Cardiol. 34(4): 379-388. doi:10.1006/jmcc.2002.1526. PMID:11991728.
    • (2002) J. Mol. Cell. Cardiol. , vol.34 , Issue.4 , pp. 379-388
    • Sawyer, D.B.1    Siwik, D.A.2    Xiao, L.3    Pimentel, D.R.4    Singh, K.5    Colucci, W.S.6
  • 32
    • 0020424153 scopus 로고
    • Role of free radicals in catecholamine-induced cardiomyopathy
    • doi:10.1139/y82-207. PMID:7151008
    • Singal, P.K., Kapur, N., Dhillon, K.S., Beamish, R.E., and Dhalla, N.S. 1982. Role of free radicals in catecholamine-induced cardiomyopathy. Can. J. Physiol. Pharmacol. 60(11): 1390-1397. doi:10.1139/y82-207. PMID:7151008.
    • (1982) Can. J. Physiol. Pharmacol. , vol.60 , Issue.11 , pp. 1390-1397
    • Singal, P.K.1    Kapur, N.2    Dhillon, K.S.3    Beamish, R.E.4    Dhalla, N.S.5
  • 33
    • 0034995893 scopus 로고    scopus 로고
    • Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts
    • PMID:11121376
    • Siwik, D.A., Pagano, P.J., and Colucci, W.S. 2001. Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. Am. J. Physiol. Cell Physiol. 280(1): C53-C60. PMID:11121376.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280 , Issue.1
    • Siwik, D.A.1    Pagano, P.J.2    Colucci, W.S.3
  • 34
    • 0025770664 scopus 로고
    • Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system
    • doi:10.1161/01.CIR.83.6.1849. PMID:1828192
    • Weber, K.T., and Brilla, C.G. 1991. Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation, 83(6): 1849-1865. doi:10.1161/01.CIR.83.6.1849. PMID:1828192.
    • (1991) Circulation , vol.83 , Issue.6 , pp. 1849-1865
    • Weber, K.T.1    Brilla, C.G.2
  • 35
    • 0033572352 scopus 로고    scopus 로고
    • Inhibitory effect of quercetin metabolites and their related derivatives on copper ioninduced lipid peroxidation in human low-density lipoprotein
    • doi:10.1006/abbi.1999.1516. PMID:10600174
    • Yamamoto, N., Moon, J.H., Tsushida, T., Nagao, A., and Terao, J. 1999. Inhibitory effect of quercetin metabolites and their related derivatives on copper ioninduced lipid peroxidation in human low-density lipoprotein. Arch. Biochem. Biophys. 372(2): 347-354. doi:10.1006/abbi.1999.1516. PMID:10600174.
    • (1999) Arch. Biochem. Biophys. , vol.372 , Issue.2 , pp. 347-354
    • Yamamoto, N.1    Moon, J.H.2    Tsushida, T.3    Nagao, A.4    Terao, J.5
  • 36
    • 28044467747 scopus 로고    scopus 로고
    • Bioavailability and metabolic pharmacokinetics of rutin and quercetin in rats
    • Yang, C.Y., Hsiu, S.L., Wen, K.C., Lin, S.P., Tsai, S.Y., Hou, Y.C., et al. 2005. Bioavailability and metabolic pharmacokinetics of rutin and quercetin in rats. J. Food Drug Anal. 13(3): 244-250.
    • (2005) J. Food Drug Anal. , vol.13 , Issue.3 , pp. 244-250
    • Yang, C.Y.1    Hsiu, S.L.2    Wen, K.C.3    Lin, S.P.4    Tsai, S.Y.5    Hou, Y.C.6
  • 37
    • 43549097537 scopus 로고    scopus 로고
    • Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat
    • doi:10.1016/j.ejphar.2008.02.057. PMID: 18384769
    • Zhou, R., Xu, Q., Zheng, P., Yan, L., Zheng, J., and Dai, G. 2008. Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat. Eur. J. Pharmacol. 586(1): 244-250. doi:10.1016/j.ejphar.2008.02.057. PMID: 18384769.
    • (2008) Eur. J. Pharmacol. , vol.586 , Issue.1 , pp. 244-250
    • Zhou, R.1    Xu, Q.2    Zheng, P.3    Yan, L.4    Zheng, J.5    Dai, G.6


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