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Volumn 4, Issue 8, 2013, Pages 653-661

Kisspeptin/KISSIR system in breast cancer

Author keywords

Breast cancer; G protein coupled receptor; Invasion; KISS1R; Kisspeptin; Metastasis

Indexed keywords

ESTRADIOL; G PROTEIN COUPLED RECEPTOR; KISSPEPTIN; KISSPEPTIN 1 RECEPTOR; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 84885440768     PISSN: None     EISSN: 18379664     Source Type: Journal    
DOI: 10.7150/jca.7626     Document Type: Review
Times cited : (45)

References (103)
  • 1
    • 77950580049 scopus 로고    scopus 로고
    • The KISS1 metastasis suppressor: a good night kiss for disseminated cancer cells
    • Beck BH, Welch DR. The KISS1 metastasis suppressor: a good night kiss for disseminated cancer cells. Eur J Cancer. 2005; 46: 1283-9.
    • (2005) Eur J Cancer , vol.46 , pp. 1283-1289
    • Beck, B.H.1    Welch, D.R.2
  • 2
    • 0030993620 scopus 로고    scopus 로고
    • Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display
    • Lee JH, Welch DR. Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display. Int J Cancer. 1997; 71: 1035-44.
    • (1997) Int J Cancer , vol.71 , pp. 1035-1044
    • Lee, J.H.1    Welch, D.R.2
  • 4
    • 33845885316 scopus 로고    scopus 로고
    • Kisspeptins are novel potent vasoconstrictors in humans, with a discrete localization of their receptor, G protein-coupled receptor 54, to atherosclerosis-prone vessels
    • Mead EJ, Maguire JJ, Kuc RE, Davenport AP. Kisspeptins are novel potent vasoconstrictors in humans, with a discrete localization of their receptor, G protein-coupled receptor 54, to atherosclerosis-prone vessels. Endocrinology. 2007; 148: 140-7.
    • (2007) Endocrinology , vol.148 , pp. 140-147
    • Mead, E.J.1    Maguire, J.J.2    Kuc, R.E.3    Davenport, A.P.4
  • 5
    • 0035978639 scopus 로고    scopus 로고
    • Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor
    • Ohtaki T, Shintani Y, Honda S, Matsumoto H, Hori A, Kanehashi K, et al. Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature. 2001; 411: 613-7.
    • (2001) Nature , vol.411 , pp. 613-617
    • Ohtaki, T.1    Shintani, Y.2    Honda, S.3    Matsumoto, H.4    Hori, A.5    Kanehashi, K.6
  • 9
    • 78650092251 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function
    • Kirby HR, Maguire JJ, Colledge WH, Davenport AP. International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function. Pharmacol Rev. 2010; 62: 565-78.
    • (2010) Pharmacol Rev. , vol.62 , pp. 565-578
    • Kirby, H.R.1    Maguire, J.J.2    Colledge, W.H.3    Davenport, A.P.4
  • 11
    • 84870178932 scopus 로고    scopus 로고
    • Single-cell analyses reveal that KISS1R-expressing cells undergo sustained kisspeptin-induced signaling that is dependent upon an influx of extracellular Ca2+
    • doi:10.1210/en.2012-1747
    • Babwah AV, Pampillo M, Min L, Kaiser UB, Bhattacharya M. Single-cell analyses reveal that KISS1R-expressing cells undergo sustained kisspeptin-induced signaling that is dependent upon an influx of extracellular Ca2+. Endocrinology. 2012; 153: 5875-87. doi:10.1210/en.2012-1747.
    • (2012) Endocrinology , vol.153 , pp. 5875-87
    • Babwah, A.V.1    Pampillo, M.2    Min, L.3    Kaiser, U.B.4    Bhattacharya, M.5
  • 13
    • 77958596455 scopus 로고    scopus 로고
    • GPR54 regulates ERK1/2 activity and hypothalamic gene expression in a Galpha(q/11) and beta-arrestin-dependent manner
    • Szereszewski JM, Pampillo M, Ahow MR, Offermanns S, Bhattacharya M, Babwah AV. GPR54 regulates ERK1/2 activity and hypothalamic gene expression in a Galpha(q/11) and beta-arrestin-dependent manner. PLoS One. 2010; 5: e12964.
    • (2010) PLoS One , vol.5
    • Szereszewski, J.M.1    Pampillo, M.2    Ahow, M.R.3    Offermanns, S.4    Bhattacharya, M.5    Babwah, A.V.6
  • 14
    • 58049213895 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by kisspeptins through GPR54: do multiple signals underlie function diversity?
    • doi:10.1016/j.peptides.2008.07.025
    • Castano JP, Martinez-Fuentes AJ, Gutierrez-Pascual E, Vaudry H, Tena-Sempere M, Malagon MM. Intracellular signaling pathways activated by kisspeptins through GPR54: do multiple signals underlie function diversity? Peptides. 2009; 30: 10-5. doi:10.1016/j.peptides.2008.07.025.
    • (2009) Peptides , vol.30 , pp. 10-15
    • Castano, J.P.1    Martinez-Fuentes, A.J.2    Gutierrez-Pascual, E.3    Vaudry, H.4    Tena-Sempere, M.5    Malagon, M.M.6
  • 15
    • 69249219124 scopus 로고    scopus 로고
    • Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines
    • doi:10.1016/j.mce.2009.06.011
    • Novaira HJ, Ng Y, Wolfe A, Radovick S. Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines. Molecular and cellular endocrinology. 2009; 311: 126-34. doi:10.1016/j.mce.2009.06.011.
    • (2009) Molecular and cellular endocrinology , vol.311 , pp. 126-134
    • Novaira, H.J.1    Ng, Y.2    Wolfe, A.3    Radovick, S.4
  • 16
    • 0029719789 scopus 로고    scopus 로고
    • Desensitization of G protein-coupled receptors
    • Discussion 52-3
    • Freedman NJ, Lefkowitz RJ. Desensitization of G protein-coupled receptors. Recent Prog Horm Res. 1996; 51: 319-51; discussion 52-3.
    • (1996) Recent Prog Horm Res. , vol.51 , pp. 319-351
    • Freedman, N.J.1    Lefkowitz, R.J.2
  • 17
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G protein-coupled receptor regulation
    • Krupnick JG, Benovic JL. The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol. 1998; 38: 289-319.
    • (1998) Annu Rev Pharmacol Toxicol. , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 18
    • 79953214036 scopus 로고    scopus 로고
    • KISS1R intracellular trafficking and degradation: effect of the Arg386Pro disease-associated mutation
    • doi:10.1210/en.2010-0903
    • Bianco SD, Vandepas L, Correa-Medina M, Gereben B, Mukherjee A, Kuohung W, et al. KISS1R intracellular trafficking and degradation: effect of the Arg386Pro disease-associated mutation. Endocrinology. 2011; 152: 1616-26. doi:10.1210/en.2010-0903.
    • (2011) Endocrinology , vol.152 , pp. 1616-1626
    • Bianco, S.D.1    Vandepas, L.2    Correa-Medina, M.3    Gereben, B.4    Mukherjee, A.5    Kuohung, W.6
  • 19
    • 0036473397 scopus 로고    scopus 로고
    • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
    • Luttrell LM, Lefkowitz RJ. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci. 2002; 115: 455-65.
    • (2002) J Cell Sci. , vol.115 , pp. 455-465
    • Luttrell, L.M.1    Lefkowitz, R.J.2
  • 20
    • 84878652051 scopus 로고    scopus 로고
    • PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types
    • doi:10.1007/s00280-013-2121-1
    • Britten CD. PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types. Cancer chemotherapy and pharmacology. 2013; 71: 1395-409. doi:10.1007/s00280-013-2121-1.
    • (2013) Cancer chemotherapy and pharmacology , vol.71 , pp. 1395-1409
    • Britten, C.D.1
  • 21
    • 84864067222 scopus 로고    scopus 로고
    • Kisspeptins and reproduction: physiological roles and regulatory mechanisms
    • Pinilla L, Aguilar E, Dieguez C, Millar RP, Tena-Sempere M. Kisspeptins and reproduction: physiological roles and regulatory mechanisms. Physiol Rev. 2012; 92: 1235-316.
    • (2012) Physiol Rev. , vol.92 , pp. 1235-1316
    • Pinilla, L.1    Aguilar, E.2    Dieguez, C.3    Millar, R.P.4    Tena-Sempere, M.5
  • 24
    • 2342422189 scopus 로고    scopus 로고
    • Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts
    • Bilban M, Ghaffari-Tabrizi N, Hintermann E, Bauer S, Molzer S, Zoratti C, et al. Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts. J Cell Sci. 2004; 117: 1319-28.
    • (2004) J Cell Sci. , vol.117 , pp. 1319-1328
    • Bilban, M.1    Ghaffari-Tabrizi, N.2    Hintermann, E.3    Bauer, S.4    Molzer, S.5    Zoratti, C.6
  • 25
    • 77952938368 scopus 로고    scopus 로고
    • Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2-and Sp1-mediated Bmp7 expression
    • Yi T, Tan K, Cho SG, Wang Y, Luo J, Zhang W, et al. Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2-and Sp1-mediated Bmp7 expression. The Journal of biological chemistry. 2010; 285: 17811-20.
    • (2010) The Journal of biological chemistry , vol.285 , pp. 17811-17820
    • Yi, T.1    Tan, K.2    Cho, S.G.3    Wang, Y.4    Luo, J.5    Zhang, W.6
  • 26
  • 27
    • 28544441746 scopus 로고    scopus 로고
    • Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins
    • Navenot JM, Wang Z, Chopin M, Fujii N, Peiper SC. Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins. Cancer research. 2005; 65: 10450-6.
    • (2005) Cancer research , vol.65 , pp. 10450-10456
    • Navenot, J.M.1    Wang, Z.2    Chopin, M.3    Fujii, N.4    Peiper, S.C.5
  • 28
    • 0035887152 scopus 로고    scopus 로고
    • Loss of expression of the metastasis suppressor gene KiSS1 during melanoma progression and its association with LOH of chromosome 6q16.3-q23
    • Shirasaki F, Takata M, Hatta N, Takehara K. Loss of expression of the metastasis suppressor gene KiSS1 during melanoma progression and its association with LOH of chromosome 6q16.3-q23. Cancer research. 2001; 61: 7422-5.
    • (2001) Cancer research , vol.61 , pp. 7422-7425
    • Shirasaki, F.1    Takata, M.2    Hatta, N.3    Takehara, K.4
  • 29
    • 0036090281 scopus 로고    scopus 로고
    • Metastin receptor is overexpressed in papillary thyroid cancer and activates MAP kinase in thyroid cancer cells
    • Ringel MD, Hardy E, Bernet VJ, Burch HB, Schuppert F, Burman KD, et al. Metastin receptor is overexpressed in papillary thyroid cancer and activates MAP kinase in thyroid cancer cells. J Clin Endocrinol Metab. 2002; 87: 2399.
    • (2002) J Clin Endocrinol Metab. , vol.87 , pp. 2399
    • Ringel, M.D.1    Hardy, E.2    Bernet, V.J.3    Burch, H.B.4    Schuppert, F.5    Burman, K.D.6
  • 30
    • 24344448213 scopus 로고    scopus 로고
    • KiSS-1/G protein-coupled receptor 54 metastasis suppressor pathway increases myocyte-enriched calcineurin interacting protein 1 expression and chronically inhibits calcineurin activity
    • Stathatos N, Bourdeau I, Espinosa AV, Saji M, Vasko VV, Burman KD, et al. KiSS-1/G protein-coupled receptor 54 metastasis suppressor pathway increases myocyte-enriched calcineurin interacting protein 1 expression and chronically inhibits calcineurin activity. J Clin Endocrinol Metab. 2005; 90: 5432-40.
    • (2005) J Clin Endocrinol Metab. , vol.90 , pp. 5432-5440
    • Stathatos, N.1    Bourdeau, I.2    Espinosa, A.V.3    Saji, M.4    Vasko, V.V.5    Burman, K.D.6
  • 31
    • 38449097370 scopus 로고    scopus 로고
    • Expression of KiSS-1, matrix metalloproteinase-9, nuclear factor-kappaBp65 in ovarian tumour
    • Gao GL, Liu LD, Zou XS, Chen WX. [Expression of KiSS-1, matrix metalloproteinase-9, nuclear factor-kappaBp65 in ovarian tumour]. Zhonghua Fu Chan Ke Za Zhi. 2007; 42: 34-8.
    • (2007) Zhonghua Fu Chan Ke Za Zhi , vol.42 , pp. 34-38
    • Gao, G.L.1    Liu, L.D.2    Zou, X.S.3    Chen, W.X.4
  • 32
    • 34249913707 scopus 로고    scopus 로고
    • Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer
    • Hata K, Dhar DK, Watanabe Y, Nakai H, Hoshiai H. Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer. Eur J Cancer. 2007; 43: 1452-9.
    • (2007) Eur J Cancer , vol.43 , pp. 1452-1459
    • Hata, K.1    Dhar, D.K.2    Watanabe, Y.3    Nakai, H.4    Hoshiai, H.5
  • 33
    • 43749084143 scopus 로고    scopus 로고
    • Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels
    • Zhang C, Roepke TA, Kelly MJ, Ronnekleiv OK. Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels. J Neurosci. 2008; 28: 4423-34.
    • (2008) J Neurosci. , vol.28 , pp. 4423-4434
    • Zhang, C.1    Roepke, T.A.2    Kelly, M.J.3    Ronnekleiv, O.K.4
  • 34
    • 33750090751 scopus 로고    scopus 로고
    • Expression and clinical significance of KISS-1 and GPR54 mRNA in endometrial carcinoma
    • Jiang T, Zhang SL, Lin B, Meng LR, Gao H. [Expression and clinical significance of KISS-1 and GPR54 mRNA in endometrial carcinoma]. Zhonghua Zhong Liu Za Zhi. 2005; 27: 229-31.
    • (2005) Zhonghua Zhong Liu Za Zhi , vol.27 , pp. 229-231
    • Jiang, T.1    Zhang, S.L.2    Lin, B.3    Meng, L.R.4    Gao, H.5
  • 35
    • 80052451521 scopus 로고    scopus 로고
    • KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients
    • doi:10.1016/j.ajpath.2011.05.009
    • Cebrian V, Fierro M, Orenes-Pinero E, Grau L, Moya P, Ecke T, et al. KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients. The American journal of pathology. 2011; 179: 540-6. doi:10.1016/j.ajpath.2011.05.009.
    • (2011) The American journal of pathology , vol.179 , pp. 540-546
    • Cebrian, V.1    Fierro, M.2    Orenes-Pinero, E.3    Grau, L.4    Moya, P.5    Ecke, T.6
  • 36
    • 0345269134 scopus 로고    scopus 로고
    • Expression profiling of osteosarcoma cells transfected with MDR1 and NEO genes: regulation of cell adhesion, apoptosis, and tumor suppression-related genes
    • Sanchez-Carbayo M, Belbin TJ, Scotlandi K, Prystowsky M, Baldini N, Childs G, et al. Expression profiling of osteosarcoma cells transfected with MDR1 and NEO genes: regulation of cell adhesion, apoptosis, and tumor suppression-related genes. Lab Invest. 2003; 83: 507-17.
    • (2003) Lab Invest. , vol.83 , pp. 507-517
    • Sanchez-Carbayo, M.1    Belbin, T.J.2    Scotlandi, K.3    Prystowsky, M.4    Baldini, N.5    Childs, G.6
  • 37
    • 4143123501 scopus 로고    scopus 로고
    • Downregulation of KiSS-1 expression is responsible for tumor invasion and worse prognosis in gastric carcinoma
    • Dhar DK, Naora H, Kubota H, Maruyama R, Yoshimura H, Tonomoto Y, et al. Downregulation of KiSS-1 expression is responsible for tumor invasion and worse prognosis in gastric carcinoma. Int J Cancer. 2004; 111: 868-72.
    • (2004) Int J Cancer , vol.111 , pp. 868-872
    • Dhar, D.K.1    Naora, H.2    Kubota, H.3    Maruyama, R.4    Yoshimura, H.5    Tonomoto, Y.6
  • 38
    • 34248395929 scopus 로고    scopus 로고
    • Reduced protein expression of metastasis-related genes (nm23, KISS1, KAI1 and p53) in lymph node and liver metastases of gastric cancer
    • Guan-Zhen Y, Ying C, Can-Rong N, Guo-Dong W, Jian-Xin Q, Jie-Jun W. Reduced protein expression of metastasis-related genes (nm23, KISS1, KAI1 and p53) in lymph node and liver metastases of gastric cancer. Int J Exp Pathol. 2007; 88: 175-83.
    • (2007) Int J Exp Pathol. , vol.88 , pp. 175-183
    • Guan-Zhen, Y.1    Ying, C.2    Can-Rong, N.3    Guo-Dong, W.4    Jian-Xin, Q.5    Jie-Jun, W.6
  • 39
    • 1642329111 scopus 로고    scopus 로고
    • Clinical significance of the loss of KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in esophageal squamous cell carcinoma
    • Ikeguchi M, Yamaguchi K, Kaibara N. Clinical significance of the loss of KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in esophageal squamous cell carcinoma. Clin Cancer Res. 2004; 10: 1379-83.
    • (2004) Clin Cancer Res. , vol.10 , pp. 1379-1383
    • Ikeguchi, M.1    Yamaguchi, K.2    Kaibara, N.3
  • 43
    • 57849161861 scopus 로고    scopus 로고
    • From KISS1 to kisspeptins: An historical perspective and suggested nomenclature
    • Gottsch ML, Clifton DK, Steiner RA. From KISS1 to kisspeptins: An historical perspective and suggested nomenclature. Peptides. 2009; 30: 4-9.
    • (2009) Peptides , vol.30 , pp. 4-9
    • Gottsch, M.L.1    Clifton, D.K.2    Steiner, R.A.3
  • 45
    • 84868002638 scopus 로고    scopus 로고
    • KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis
    • Cho SG, Li D, Tan K, Siwko SK, Liu M. KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis. Cancer Metastasis Rev. 2012; 31: 585-91.
    • (2012) Cancer Metastasis Rev. , vol.31 , pp. 585-591
    • Cho, S.G.1    Li, D.2    Tan, K.3    Siwko, S.K.4    Liu, M.5
  • 46
    • 84866182562 scopus 로고    scopus 로고
    • KISS-1 inhibits the proliferation and invasion of gastric carcinoma cells
    • doi:10.3748/wjg.v18.i15.1827
    • Li N, Wang HX, Zhang J, Ye YP, He GY. KISS-1 inhibits the proliferation and invasion of gastric carcinoma cells. World journal of gastroenterology: WJG. 2012; 18: 1827-33. doi:10.3748/wjg.v18.i15.1827.
    • (2012) World journal of gastroenterology: WJG , vol.18 , pp. 1827-1833
    • Li, N.1    Wang, H.X.2    Zhang, J.3    Ye, Y.P.4    He, G.Y.5
  • 47
    • 66849129313 scopus 로고    scopus 로고
    • Activation of Rho and Rho-associated kinase by GPR54 and KiSS1 metastasis suppressor gene product induces changes of cell morphology and contributes to apoptosis
    • doi:10.1124/mol.109.055095
    • Navenot JM, Fujii N, Peiper SC. Activation of Rho and Rho-associated kinase by GPR54 and KiSS1 metastasis suppressor gene product induces changes of cell morphology and contributes to apoptosis. Molecular pharmacology. 2009; 75: 1300-6. doi:10.1124/mol.109.055095.
    • (2009) Molecular pharmacology , vol.75 , pp. 1300-1306
    • Navenot, J.M.1    Fujii, N.2    Peiper, S.C.3
  • 48
    • 70149121279 scopus 로고    scopus 로고
    • Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation
    • doi:10.1158/0008-5472.can-09-0476
    • Cho SG, Yi Z, Pang X, Yi T, Wang Y, Luo J, et al. Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation. Cancer research. 2009; 69: 7062-70. doi:10.1158/0008-5472.can-09-0476.
    • (2009) Cancer research , vol.69 , pp. 7062-7070
    • Cho, S.G.1    Yi, Z.2    Pang, X.3    Yi, T.4    Wang, Y.5    Luo, J.6
  • 50
    • 84856901966 scopus 로고    scopus 로고
    • KiSS1/GPR54 and estrogen-related gene expression profiles in primary breast cancer
    • Jarzabek K, Kozlowski L, Milewski R, Wolczynski S. KiSS1/GPR54 and estrogen-related gene expression profiles in primary breast cancer. Oncol Lett. 2012; 3: 930-4.
    • (2012) Oncol Lett. , vol.3 , pp. 930-934
    • Jarzabek, K.1    Kozlowski, L.2    Milewski, R.3    Wolczynski, S.4
  • 51
    • 64849103118 scopus 로고    scopus 로고
    • Clinical significance of plasma metastin level in pancreatic cancer patients
    • Katagiri F, Nagai K, Kida A, Tomita K, Oishi S, Takeyama M, et al. Clinical significance of plasma metastin level in pancreatic cancer patients. Oncol Rep. 2009; 21: 815-9.
    • (2009) Oncol Rep. , vol.21 , pp. 815-819
    • Katagiri, F.1    Nagai, K.2    Kida, A.3    Tomita, K.4    Oishi, S.5    Takeyama, M.6
  • 52
    • 34547814250 scopus 로고    scopus 로고
    • The missing kiss of life: transcriptional activity of the metastasis suppressor gene KiSS1 in early breast cancer
    • Kostadima L, Pentheroudakis G, Pavlidis N. The missing kiss of life: transcriptional activity of the metastasis suppressor gene KiSS1 in early breast cancer. Anticancer Res. 2007; 27: 2499-504.
    • (2007) Anticancer Res. , vol.27 , pp. 2499-2504
    • Kostadima, L.1    Pentheroudakis, G.2    Pavlidis, N.3
  • 54
    • 84872764422 scopus 로고    scopus 로고
    • KiSS-1 methylation and protein expression patterns contribute to diagnostic and prognostic assessments in tissue specimens for colorectal cancer
    • Moya P, Esteban S, Fernandez-Suarez A, Maestro M, Morente M, Sanchez-Carbayo M. KiSS-1 methylation and protein expression patterns contribute to diagnostic and prognostic assessments in tissue specimens for colorectal cancer. Tumour Biol. 2013; 34: 471-9.
    • (2013) Tumour Biol. , vol.34 , pp. 471-479
    • Moya, P.1    Esteban, S.2    Fernandez-Suarez, A.3    Maestro, M.4    Morente, M.5    Sanchez-Carbayo, M.6
  • 56
    • 38349053162 scopus 로고    scopus 로고
    • Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma
    • Prentice LM, Klausen C, Kalloger S, Kobel M, McKinney S, Santos JL, et al. Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma. BMC Med. 2007; 5: 33.
    • (2007) BMC Med. , vol.5 , pp. 33
    • Prentice, L.M.1    Klausen, C.2    Kalloger, S.3    Kobel, M.4    McKinney, S.5    Santos, J.L.6
  • 57
    • 0141639653 scopus 로고    scopus 로고
    • Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in hepatocellular carcinoma
    • Ikeguchi M, Hirooka Y, Kaibara N. Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2003; 129: 531-5.
    • (2003) J Cancer Res Clin Oncol. , vol.129 , pp. 531-535
    • Ikeguchi, M.1    Hirooka, Y.2    Kaibara, N.3
  • 58
    • 56249138015 scopus 로고    scopus 로고
    • Expression of tumor metastasis-suppressor gene KiSS-1 and matrix metalloproteinase-9 in portal vein tumor thrombus of hepatocellular carcinoma
    • Hou YK, Wang Y, Cong WM, Wu MC. [Expression of tumor metastasis-suppressor gene KiSS-1 and matrix metalloproteinase-9 in portal vein tumor thrombus of hepatocellular carcinoma]. Ai Zheng. 2007; 26: 591-5.
    • (2007) Ai Zheng , vol.26 , pp. 591-595
    • Hou, Y.K.1    Wang, Y.2    Cong, W.M.3    Wu, M.C.4
  • 59
    • 33847101837 scopus 로고    scopus 로고
    • KiSS-1 overexpression as an independent prognostic marker in hepatocellular carcinoma: an immunohistochemical study
    • Schmid K, Wang X, Haitel A, Sieghart W, Peck-Radosavljevic M, Bodingbauer M, et al. KiSS-1 overexpression as an independent prognostic marker in hepatocellular carcinoma: an immunohistochemical study. Virchows Arch. 2007; 450: 143-9.
    • (2007) Virchows Arch. , vol.450 , pp. 143-149
    • Schmid, K.1    Wang, X.2    Haitel, A.3    Sieghart, W.4    Peck-Radosavljevic, M.5    Bodingbauer, M.6
  • 60
    • 0030956852 scopus 로고    scopus 로고
    • Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1
    • Lee JH, Welch DR. Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1. Cancer research. 1997; 57: 2384-7.
    • (1997) Cancer research , vol.57 , pp. 2384-2387
    • Lee, J.H.1    Welch, D.R.2
  • 61
    • 0034050902 scopus 로고    scopus 로고
    • Systematic variation in gene expression patterns in human cancer cell lines
    • Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman P, et al. Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet. 2000; 24: 227-35.
    • (2000) Nat Genet. , vol.24 , pp. 227-235
    • Ross, D.T.1    Scherf, U.2    Eisen, M.B.3    Perou, C.M.4    Rees, C.5    Spellman, P.6
  • 62
    • 67650456890 scopus 로고    scopus 로고
    • MDA-MB-435 and M14 cell lines: identical but not M14 melanoma?
    • Chambers AF. MDA-MB-435 and M14 cell lines: identical but not M14 melanoma? Cancer research. 2009; 69: 5292-3.
    • (2009) Cancer research , vol.69 , pp. 5292-5293
    • Chambers, A.F.1
  • 63
    • 80054020596 scopus 로고    scopus 로고
    • Haploinsufficiency in the prometastasis Kiss1 receptor Gpr54 delays breast tumor initiation, progression, and lung metastasis
    • Cho SG, Wang Y, Rodriguez M, Tan K, Zhang W, Luo J, et al. Haploinsufficiency in the prometastasis Kiss1 receptor Gpr54 delays breast tumor initiation, progression, and lung metastasis. Cancer research. 2011; 71: 6535-46.
    • (2011) Cancer research , vol.71 , pp. 6535-6546
    • Cho, S.G.1    Wang, Y.2    Rodriguez, M.3    Tan, K.4    Zhang, W.5    Luo, J.6
  • 65
    • 84864352591 scopus 로고    scopus 로고
    • A logistic regression model for predicting axillary lymph node metastases in early breast carcinoma patients
    • Xie F, Yang H, Wang S, Zhou B, Tong F, Yang D, et al. A logistic regression model for predicting axillary lymph node metastases in early breast carcinoma patients. Sensors (Basel). 2012; 12: 9936-50.
    • (2012) Sensors (Basel) , vol.12 , pp. 9936-9950
    • Xie, F.1    Yang, H.2    Wang, S.3    Zhou, B.4    Tong, F.5    Yang, D.6
  • 66
    • 84858258014 scopus 로고    scopus 로고
    • Expressional alterations and transcript isoforms of metastasis suppressor genes (KAI1 and KiSS1) in breast cancer patients
    • Mooez S, Malik FA, Kayani MA, Rashid R, Zahid A, Khan A. Expressional alterations and transcript isoforms of metastasis suppressor genes (KAI1 and KiSS1) in breast cancer patients. Asian Pac J Cancer Prev. 2011; 12: 2785-91.
    • (2011) Asian Pac J Cancer Prev. , vol.12 , pp. 2785-2791
    • Mooez, S.1    Malik, F.A.2    Kayani, M.A.3    Rashid, R.4    Zahid, A.5    Khan, A.6
  • 67
    • 84859638293 scopus 로고    scopus 로고
    • Clinical significance of KISS1 protein expression for brain invasion and metastasis
    • Ulasov IV, Kaverina NV, Pytel P, Thaci B, Liu F, Hurst DR, et al. Clinical significance of KISS1 protein expression for brain invasion and metastasis. Cancer. 2012; 118: 2096-105.
    • (2012) Cancer , vol.118 , pp. 2096-2105
    • Ulasov, I.V.1    Kaverina, N.V.2    Pytel, P.3    Thaci, B.4    Liu, F.5    Hurst, D.R.6
  • 69
    • 84856447171 scopus 로고    scopus 로고
    • ERalpha, microRNAs, and the epithelial-mesenchymal transition in breast cancer
    • Guttilla IK, Adams BD, White BA. ERalpha, microRNAs, and the epithelial-mesenchymal transition in breast cancer. Trends Endocrinol Metab. 2012; 23: 73-82.
    • (2012) Trends Endocrinol Metab. , vol.23 , pp. 73-82
    • Guttilla, I.K.1    Adams, B.D.2    White, B.A.3
  • 71
    • 79952621557 scopus 로고    scopus 로고
    • Estrogen and progesterone in normal mammary gland development and in cancer
    • Stingl J. Estrogen and progesterone in normal mammary gland development and in cancer. Horm Cancer. 2011; 2: 85-90.
    • (2011) Horm Cancer , vol.2 , pp. 85-90
    • Stingl, J.1
  • 72
    • 77951546955 scopus 로고    scopus 로고
    • GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
    • Yan W, Cao QJ, Arenas RB, Bentley B, Shao R. GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition. The Journal of biological chemistry. 2010; 285: 14042-51.
    • (2010) The Journal of biological chemistry , vol.285 , pp. 14042-14051
    • Yan, W.1    Cao, Q.J.2    Arenas, R.B.3    Bentley, B.4    Shao, R.5
  • 75
    • 33646575920 scopus 로고    scopus 로고
    • Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha
    • Franceschini I, Lomet D, Cateau M, Delsol G, Tillet Y, Caraty A. Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha. Neurosci Lett. 2006; 401: 225-30.
    • (2006) Neurosci Lett. , vol.401 , pp. 225-230
    • Franceschini, I.1    Lomet, D.2    Cateau, M.3    Delsol, G.4    Tillet, Y.5    Caraty, A.6
  • 77
    • 0021723038 scopus 로고
    • Prognostic significance of estrogen receptor status in breast cancer in relation to tumor stage, axillary node metastasis, and histopathologic grading
    • Parl FF, Schmidt BP, Dupont WD, Wagner RK. Prognostic significance of estrogen receptor status in breast cancer in relation to tumor stage, axillary node metastasis, and histopathologic grading. Cancer. 1984; 54: 2237-42.
    • (1984) Cancer , vol.54 , pp. 2237-2242
    • Parl, F.F.1    Schmidt, B.P.2    Dupont, W.D.3    Wagner, R.K.4
  • 78
    • 35948954029 scopus 로고    scopus 로고
    • High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors
    • Marot D, Bieche I, Aumas C, Esselin S, Bouquet C, Vacher S, et al. High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors. Endocr Relat Cancer. 2007; 14: 691-702.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 691-702
    • Marot, D.1    Bieche, I.2    Aumas, C.3    Esselin, S.4    Bouquet, C.5    Vacher, S.6
  • 79
    • 84878428917 scopus 로고    scopus 로고
    • KISS1R Induces Invasiveness of Estrogen Receptor-Negative Human Mammary Epithelial and Breast Cancer Cells
    • Cvetkovic D, Dragan M, Leith SJ, Mir ZM, Leong HS, Pampillo M, et al. KISS1R Induces Invasiveness of Estrogen Receptor-Negative Human Mammary Epithelial and Breast Cancer Cells. Endocrinology. 2013.
    • (2013) Endocrinology
    • Cvetkovic, D.1    Dragan, M.2    Leith, S.J.3    Mir, Z.M.4    Leong, H.S.5    Pampillo, M.6
  • 80
    • 78149357363 scopus 로고    scopus 로고
    • Kisspeptin-10 inhibits bone-directed migration of GPR54-positive breast cancer cells: Evidence for a dose-window effect
    • Olbrich T, Ziegler E, Turk G, Schubert A, Emons G, Grundker C. Kisspeptin-10 inhibits bone-directed migration of GPR54-positive breast cancer cells: Evidence for a dose-window effect. Gynecol Oncol. 2010; 119: 571-8.
    • (2010) Gynecol Oncol. , vol.119 , pp. 571-578
    • Olbrich, T.1    Ziegler, E.2    Turk, G.3    Schubert, A.4    Emons, G.5    Grundker, C.6
  • 81
    • 77954897620 scopus 로고    scopus 로고
    • KISS1 is down-regulated by 17beta-estradiol in MDA-MB-231 cells through a nonclassical mechanism and loss of ribonucleic acid polymerase II binding at the proximal promoter
    • Huijbregts L, de Roux N. KISS1 is down-regulated by 17beta-estradiol in MDA-MB-231 cells through a nonclassical mechanism and loss of ribonucleic acid polymerase II binding at the proximal promoter. Endocrinology. 2010; 151: 3764-72.
    • (2010) Endocrinology , vol.151 , pp. 3764-3772
    • Huijbregts, L.1    De Roux, N.2
  • 82
    • 84865963735 scopus 로고    scopus 로고
    • Promoter hypermethylation of estrogen receptor alpha gene is correlated to estrogen receptor negativity in Iranian patients with sporadic breast cancer
    • Izadi P, Noruzinia M, Karimipoor M, Karbassian MH, Akbari MT. Promoter hypermethylation of estrogen receptor alpha gene is correlated to estrogen receptor negativity in Iranian patients with sporadic breast cancer. Cell J. 2012; 14: 102-9.
    • (2012) Cell J. , vol.14 , pp. 102-109
    • Izadi, P.1    Noruzinia, M.2    Karimipoor, M.3    Karbassian, M.H.4    Akbari, M.T.5
  • 83
    • 84867644007 scopus 로고    scopus 로고
    • ERalpha positively regulated DNMT1 expression by binding to the gene promoter region in human breast cancer MCF-7 cells
    • Shi JF, Li XJ, Si XX, Li AD, Ding HJ, Han X, et al. ERalpha positively regulated DNMT1 expression by binding to the gene promoter region in human breast cancer MCF-7 cells. Biochem Biophys Res Commun. 2012; 427: 47-53.
    • (2012) Biochem Biophys Res Commun. , vol.427 , pp. 47-53
    • Shi, J.F.1    Li, X.J.2    Si, X.X.3    Li, A.D.4    Ding, H.J.5    Han, X.6
  • 84
    • 33947265489 scopus 로고    scopus 로고
    • Transcriptional regulation of KiSS-1 gene expression in metastatic melanoma by specificity protein-1 and its coactivator DRIP-130
    • Mitchell DC, Stafford LJ, Li D, Bar-Eli M, Liu M. Transcriptional regulation of KiSS-1 gene expression in metastatic melanoma by specificity protein-1 and its coactivator DRIP-130. Oncogene. 2007; 26: 1739-47.
    • (2007) Oncogene , vol.26 , pp. 1739-1747
    • Mitchell, D.C.1    Stafford, L.J.2    Li, D.3    Bar-Eli, M.4    Liu, M.5
  • 85
    • 78049309863 scopus 로고    scopus 로고
    • Assessment of constitutive activity and internalization of GPR54 (KISS1-R)
    • Pampillo M, Babwah AV. Assessment of constitutive activity and internalization of GPR54 (KISS1-R). Methods Enzymol. 2010; 484: 75-93.
    • (2010) Methods Enzymol. , vol.484 , pp. 75-93
    • Pampillo, M.1    Babwah, A.V.2
  • 86
    • 79959610178 scopus 로고    scopus 로고
    • GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness
    • Zajac M, Law J, Cvetkovic DD, Pampillo M, McColl L, Pape C, et al. GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness. PLoS One. 2011; 6: e21599.
    • (2011) PLoS One , vol.6
    • Zajac, M.1    Law, J.2    Cvetkovic, D.D.3    Pampillo, M.4    McColl, L.5    Pape, C.6
  • 87
    • 82555185376 scopus 로고    scopus 로고
    • The epidermal growth factor receptor/Erb-B/HER family in normal and malignant breast biology
    • Eccles SA. The epidermal growth factor receptor/Erb-B/HER family in normal and malignant breast biology. Int J Dev Biol. 2011; 55: 685-96.
    • (2011) Int J Dev Biol. , vol.55 , pp. 685-696
    • Eccles, S.A.1
  • 88
    • 0035846942 scopus 로고    scopus 로고
    • KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation
    • Yan C, Wang H, Boyd DD. KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation. The Journal of biological chemistry. 2001; 276: 1164-72.
    • (2001) The Journal of biological chemistry , vol.276 , pp. 1164-1172
    • Yan, C.1    Wang, H.2    Boyd, D.D.3
  • 89
    • 67651151233 scopus 로고    scopus 로고
    • Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells
    • Li TT, Alemayehu M, Aziziyeh AI, Pape C, Pampillo M, Postovit LM, et al. Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Mol Cancer Res. 2009; 7: 1064-77.
    • (2009) Mol Cancer Res. , vol.7 , pp. 1064-1077
    • Li, T.T.1    Alemayehu, M.2    Aziziyeh, A.I.3    Pape, C.4    Pampillo, M.5    Postovit, L.M.6
  • 91
    • 84859454686 scopus 로고    scopus 로고
    • Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1
    • Wang Y, Roche O, Xu C, Moriyama EH, Heir P, Chung J, et al. Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1. Proc Natl Acad Sci U S A. 2012; 109: 4892-7.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 4892-4897
    • Wang, Y.1    Roche, O.2    Xu, C.3    Moriyama, E.H.4    Heir, P.5    Chung, J.6
  • 92
  • 93
    • 80051932950 scopus 로고    scopus 로고
    • IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance
    • White CD, Li Z, Dillon DA, Sacks DB. IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance. The Journal of biological chemistry. 2011; 286: 29734-47.
    • (2011) The Journal of biological chemistry , vol.286 , pp. 29734-29747
    • White, C.D.1    Li, Z.2    Dillon, D.A.3    Sacks, D.B.4
  • 94
    • 0043093686 scopus 로고    scopus 로고
    • IQGAP proteins are integral components of cytoskeletal regulation
    • Briggs MW, Sacks DB. IQGAP proteins are integral components of cytoskeletal regulation. EMBO Rep. 2003; 4: 571-4.
    • (2003) EMBO Rep. , vol.4 , pp. 571-574
    • Briggs, M.W.1    Sacks, D.B.2
  • 95
    • 33646726750 scopus 로고    scopus 로고
    • IQGAP1 in cellular signaling: bridging the GAP
    • Brown MD, Sacks DB. IQGAP1 in cellular signaling: bridging the GAP. Trends Cell Biol. 2006; 16: 242-9.
    • (2006) Trends Cell Biol. , vol.16 , pp. 242-249
    • Brown, M.D.1    Sacks, D.B.2
  • 96
    • 84859638293 scopus 로고    scopus 로고
    • Clinical significance of KISS1 protein expression for brain invasion and metastasis
    • Ulasov IV, Kaverina NV, Pytel P, Thaci B, Liu F, Hurst DR, et al. Clinical significance of KISS1 protein expression for brain invasion and metastasis. Cancer. 2002; 118: 2096-105.
    • (2002) Cancer , vol.118 , pp. 2096-2105
    • Ulasov, I.V.1    Kaverina, N.V.2    Pytel, P.3    Thaci, B.4    Liu, F.5    Hurst, D.R.6
  • 97
    • 84872827112 scopus 로고    scopus 로고
    • Antiproliferative effects of kisspeptin10 depend on artificial GPR54 (KISS1R) expression levels
    • Ziegler E, Olbrich T, Emons G, Grundker C. Antiproliferative effects of kisspeptin10 depend on artificial GPR54 (KISS1R) expression levels. Oncol Rep. 2013; 29: 549-54.
    • (2013) Oncol Rep. , vol.29 , pp. 549-554
    • Ziegler, E.1    Olbrich, T.2    Emons, G.3    Grundker, C.4
  • 98
    • 0037020196 scopus 로고    scopus 로고
    • The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
    • Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell. 2002; 111: 29-40.
    • (2002) Cell , vol.111 , pp. 29-40
    • Debnath, J.1    Mills, K.R.2    Collins, N.L.3    Reginato, M.J.4    Muthuswamy, S.K.5    Brugge, J.S.6
  • 99
    • 84887120008 scopus 로고    scopus 로고
    • Aromatase overexpression induces malignant changes in estrogen receptor alpha negative MCF-10A cells
    • Wang J, Gildea JJ, Yue W. Aromatase overexpression induces malignant changes in estrogen receptor alpha negative MCF-10A cells. Oncogene. 2012.
    • (2012) Oncogene
    • Wang, J.1    Gildea, J.J.2    Yue, W.3
  • 101
    • 84855162544 scopus 로고    scopus 로고
    • Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells
    • Teng Y, Liu M, Cowell JK. Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells. Int J Cancer. 2011; 129: 2825-35.
    • (2011) Int J Cancer , vol.129 , pp. 2825-2835
    • Teng, Y.1    Liu, M.2    Cowell, J.K.3
  • 102
    • 84885443181 scopus 로고    scopus 로고
    • WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells
    • Teng Y, Mei Y, Hawthorn L, Cowell JK. WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells. Oncogene. 2013.
    • (2013) Oncogene
    • Teng, Y.1    Mei, Y.2    Hawthorn, L.3    Cowell, J.K.4
  • 103
    • 84865418690 scopus 로고    scopus 로고
    • Increased expression levels of WAVE3 are associated with the progression and metastasis of triple negative breast cancer
    • Kulkarni S, AugoffK, Rivera L, McCue B, Khoury T, Groman A, et al. Increased expression levels of WAVE3 are associated with the progression and metastasis of triple negative breast cancer. PLoS One. 2012; 7: e42895.
    • (2012) PLoS One , vol.7
    • Kulkarni, S.1    Augoff, K.2    Rivera, L.3    McCue, B.4    Khoury, T.5    Groman, A.6


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