KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients

American Journal of Pathology

Volumn 179, Issue 2, 2011, Pages 540-546

  Cebrian, Virginia ^a   Fierro, Marta ^a   Orenes Piero, Esteban ^a   Grau, Laura ^a   Moya, Patricia ^a   Ecke, Thorsten ^b   Alvarez, Miguel ^c   Gil, Marta ^d   Algaba, Ferran ^e   Bellmunt, Joaquin ^f   Cordon Cardo, Carlos ^g   Catto, James ^h   López Beltrán, Antonio ⁱ   Sánchez Carbayo, Marta ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b HELIOS Klinikum Bad Saarow   (Germany)

^c HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^d CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^e FUNDACIÓ PUIGVERT   (Spain)

^f HOSPITAL DEL MAR   (Spain)

^g MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^h UNIVERSITY OF SHEFFIELD   (United Kingdom)

ⁱ HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BISULFITE; METASTIN;

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER CELL; CANCER PATIENT; CANCER SURVIVAL; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE SILENCING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN METHYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; CPG ISLANDS; DISEASE-FREE SURVIVAL; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KISSPEPTINS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TREATMENT OUTCOME; URINARY BLADDER NEOPLASMS;

EID: 80052451521     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.05.009     Document Type: Article

References (30)

1. E.M. Wolff, G. Liang, and P.A. Jones Mechanisms of disease: genetic and epigenetic alterations that drive bladder cancer Nat Clin Pract Urol 2 2005 502210
2. P.A. Jones, and S.B. Baylin The fundamental role of epigenetic events in cancer Nat Rev Genet 3 2002 415 428 (Pubitemid 34587077)
3. A.P. Feinberg, R. Ohlsson, and S. Henikoff The epigenetic progenitor origin of human cancer Nat Rev Genet 7 2006 21 33 (Pubitemid 41828945)
4. J.F. Costello, M.C. Frhwald, D.J. Smiraglia, L.J. Rush, G.P. Robertson, X. Gao, F.A. Wright, J.D. Feramisco, P. Peltomki, J.C. Lang, D.E. Schuller, L. Yu, C.D. Bloomfield, M.A. Caligiuri, A. Yates, R. Nishikawa, H. Su Huang, N.J. Petrelli, X. Zhang, M.S. O'Dorisio, W.A. Held, W.K. Cavenee, and C. Plass Aberrant CpG-island methylation has non-random and tumour-type-specific patterns Nat Genet 24 2000 132 138 (Pubitemid 30094712)
5. M. Esteller CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future Oncogene 21 2002 5427 5440 (Pubitemid 34983479)
6. J.G. Herman, and S.B. Baylin Gene silencing in cancer in association with promoter hypermethylation N Engl J Med 349 2003 2042 2054 (Pubitemid 37448928)
7. J.W. Catto, A.R. Azzouzi, I. Rehman, K.M. Feeley, S.S. Cross, N. Amira, G. Fromont, M. Sibony, O. Cussenot, M. Meuth, and F.C. Hamdy Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma J Clin Oncol 23 2005 2903 2910 (Pubitemid 46224108)
8. A. Aleman, L. Adrien, L. Lopez-Serra, C. Cordon-Cardo, M. Esteller, T.J. Belbin, and M. Sanchez-Carbayo Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays Br J Cancer 98 2008 466 473 (Pubitemid 351161244)
9. T. Ohtaki, Y. Shintani, S. Honda, H. Matsumoto, A. Hori, K. Kanehashi, Y. Terao, S. Kumano, Y. Takatsu, Y. Masuda, Y. Ishibashi, T. Watanabe, M. Asada, T. Yamada, M. Suenaga, C. Kitada, S. Usuki, T. Kurokawa, H. Onda, O. Nishimura, and M. Fujino The metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor Nature 411 2001 613 617 (Pubitemid 32531412)
10. A.I. Muir, L. Chamberlain, N.A. Elshourbagy, D. Michalovich, D.J. Moore, A. Calamari, P.G. Szekeres, H.M. Sarau, J.K. Chambers, P. Murdock, K. Steplewski, U. Shabon, J.E. Miller, S.E. Middleton, J.G. Darker, C.G. Larminie, S. Wilson, D.J. Bergsma, P. Emson, R. Faull, K.L. Philpott, and D.C. Harrison AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1 J Biol Chem 276 2001 28969 28975
11. M. Kotani, M. Detheux, A. Vandenbogaerde, D. Communi, J.M. Vanderwinden, E. Le Poul, S. Brézillon, R. Tyldesley, N. Suarez-Huerta, F. Vandeput, C. Blanpain, S.N. Schiffmann, G. Vassart, and M. Parmentier The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54 J Biol Chem 276 2001 34631 34636
12. M. Sanchez-Carbayo, P. Capodieci, and C. Cordon-Cardo Tumor suppressor role of KiSS-1 in bladder cancer: loss of KiSS-1 expression in associated with bladder cancer progression and clinical outcome Am J Pathol 162 2003 609 617 (Pubitemid 36267867)
13. A. West, P.J. Vojta, D.R. Welch, and B.E. Weissman Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1) Genomics 54 1998 145 148 (Pubitemid 28536204)
14. M. Ikeguchi, K. Yamaguchi, and N. Kaibara Clinical significance of the loss of KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in esophageal squamous cell carcinoma Clin Cancer Res 10 2004 1379 1383 (Pubitemid 38365232)
15. C. Hesling, M. D'Incan, S. Mansard, F. Franck, A. Corbin-Duval, C. Chvenet, P. Déchelotte, J.C. Madelmont, A. Veyre, P. Souteyrand, and Y.J. Bignon In vivo and in situ modulation of the expression of genes involved in metastasis and angiogenesis in a patient treated with topical imiquimod for melanoma skin metastasis Br J Dermatol 150 2004 761 767 (Pubitemid 38586231)
16. D. Dhar, H. Naora, H. Kubota, R. Maruyama, H. Yoshimura, Y. Tonomoto, M. Tachibana, T. Ono, H. Otani, and N. Nagasue Downregulation of KiSS-1 expression is responsible for tumor invasion and worse prognosis in gastric carcinoma Int J Cancer 111 2004 868 872 (Pubitemid 39096235)
17. J.H. Lee, M.E. Miele, D.J. Hicks, K.K. Phillips, J.M. Trent, B.E. Weissman, and D.R. Welch KISS1, a novel human malignant melanoma metastasis-suppressor gene [Erratum appeared in J Natl Cancer Inst 1997, 89:1549] J Natl Cancer Inst 88 1996 1731 1737
18. J.H. Lee, and D.R. Welch Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display Int J Cancer 71 1997 1035 1044 (Pubitemid 27252887)
19. J.H. Lee, and D.R. Welch Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1 Cancer Res 57 1997 2384 2387 (Pubitemid 27255895)
20. T. Masui, R. Doi, T. Mori, E. Toyoda, M. Koizumi, K. Kami, D. Ito, S.C. Peiper, J.R. Broach, S. Oishi, A. Niida, N. Fujii, and M. Imamura Metastin and its variant forms suppress migration of pancreatic cancer cells Biochem Biophys Res Commun 315 2004 85 92 (Pubitemid 38175189)
21. T.A. Martin, G. Watkins, and W.G. Jiang KiSS-1 expression in human breast cancer Clin Exp Metastasis 22 2005 503 511 (Pubitemid 41750702)
22. G. Nicolle, E. Comperat, N. Nicolaew, G. Cancel-Tassin, and O. Cussenot Metastin (KISS-1) and metastin-coupled receptor (GPR54) expression in transitional cell carcinoma of the bladder Ann Oncol 18 2007 605 606
23. V.M. Zohrabian, H. Nandu, N. Gulati, G. Khitrov, C. Zhao, A. Mohan, J. Demattia, A. Braun, K. Das, R. Murali, and M. Jhanwar-Uniyal Gene expression profiling of metastatic brain cancer Oncol Rep 18 2007 321 328
24. K. Hata, D.K. Dhar, Y. Watanabe, H. Nakai, and H. Hoshiai Expression of metastin and a G-protein-coupled receptor (AXOR12) in epithelial ovarian cancer Eur J Cancer 43 2007 1452 1459 (Pubitemid 46874063)
25. A. Makri, N. Pissimissis, P. Lembessis, C. Polychronakos, and M. Koutsilieris The kisspeptin (KiSS-1)/GPR54 system in cancer biology Cancer Treat Rev 34 2008 682 692
26. S. Yamashita, Y. Tsujino, K. Moriguchi, M. Tatematsu, and T. Ushijima Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2′-deoxycytidine treatment and oligonucleotide microarray Cancer Sci 97 2006 64 71 (Pubitemid 43257029)
27. M. Sanchez-Carbayo, N.D. Socci, J. Lozano, F. Saint, and C. Cordon-Cardo Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays J Clin Oncol 24 2006 778 789 (Pubitemid 46622045)
28. Z. Kirkali, T. Chan, M. Manoharan, F. Algaba, C. Busch, L. Cheng, L. Kiemeney, M. Kriegmair, R. Montironi, W.M. Murphy, I.A. Sesterhenn, M. Tachibana, and J. Weider Bladder cancer: epidemiology, staging and grading, and diagnosis Urology 66 6 Suppl 1 2005 4 34 (Pubitemid 43049607)
29. M.F. Paz, M.F. Fraga, S. Avila, M. Guo, M. Pollan, J.G. Herman, and M. Esteller A systematic profile of DNA methylation in human cancer cell lines Cancer Res 63 2003 1114 1121 (Pubitemid 36278446)
30. B. Dawson-Saunders, and R.G. Trapp Basic & Clinical Biostatistics ed 2. 1994 Appleton & Lange Norwalk, CT