-
1
-
-
0141814637
-
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
-
de Roux N, Genin E, Carel JC, Matsuda F, Chaussain JL, Milgrom E 2003 Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci USA 100:10972-10976
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10972-10976
-
-
de Roux, N.1
Genin, E.2
Carel, J.C.3
Matsuda, F.4
Chaussain, J.L.5
Milgrom, E.6
-
2
-
-
0142091653
-
The GPR54 gene as a regulator of puberty
-
Seminara SB, Messager S, Chatzidaki EE, Thresher RR, Acierno Jr JS, Shagoury JK, Bo-Abbas Y, Kuohung W, Schwinof KM, Hendrick AG, Zahn D, Dixon J, Kaiser UB, Slaugenhaupt SA, Gusella JF, O'Rahilly S, Carlton MB, Crowley Jr WF, Aparicio SA, Colledge WH 2003 The GPR54 gene as a regulator of puberty.N Engl J Med 349:1614-1627
-
(2003)
N Engl J Med
, vol.349
, pp. 1614-1627
-
-
Seminara, S.B.1
Messager, S.2
Chatzidaki, E.E.3
Thresher, R.R.4
Acierno Jr, J.S.5
Shagoury, J.K.6
Bo-Abbas, Y.7
Kuohung, W.8
Schwinof, K.M.9
Hendrick, A.G.10
Zahn, D.11
Dixon, J.12
Kaiser, U.B.13
Slaugenhaupt, S.A.14
Gusella, J.F.15
O'Rahilly, S.16
Carlton, M.B.17
Crowley Jr, W.F.18
Aparicio, S.A.19
Colledge, W.H.20
more..
-
3
-
-
0035860778
-
The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54
-
Kotani M, Detheux M, Vandenbogaerde A, Communi D, Vanderwinden JM, Le Poul E, Brézillon S, Tyldesley R, Suarez-Huerta N, Vandeput F, Blanpain C, Schiffmann SN, Vassart G, Parmentier M 2001 The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 276:34631-34636
-
(2001)
J Biol Chem
, vol.276
, pp. 34631-34636
-
-
Kotani, M.1
Detheux, M.2
Vandenbogaerde, A.3
Communi, D.4
Vanderwinden, J.M.5
Le Poul, E.6
Brézillon, S.7
Tyldesley, R.8
Suarez-Huerta, N.9
Vandeput, F.10
Blanpain, C.11
Schiffmann, S.N.12
Vassart, G.13
Parmentier, M.14
-
4
-
-
43549083266
-
The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction
-
Popa SM, Clifton DK, Steiner RA 2008 The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction. Annu Rev Physiol 70:213-238
-
(2008)
Annu Rev Physiol
, vol.70
, pp. 213-238
-
-
Popa, S.M.1
Clifton, D.K.2
Steiner, R.A.3
-
5
-
-
13444255980
-
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54
-
Messager S, Chatzidaki EE, Ma D, Hendrick AG, Zahn D, Dixon J, Thresher RR, Malinge I, Lomet D, Carlton MB, Colledge WH, Caraty A, Aparicio SA 2005 Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci USA 102:1761-1766
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1761-1766
-
-
Messager, S.1
Chatzidaki, E.E.2
Ma, D.3
Hendrick, A.G.4
Zahn, D.5
Dixon, J.6
Thresher, R.R.7
Malinge, I.8
Lomet, D.9
Carlton, M.B.10
Colledge, W.H.11
Caraty, A.12
Aparicio, S.A.13
-
6
-
-
33751174091
-
Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats
-
Thompson EL, Murphy KG, Patterson M, Bewick GA, Stamp GW, Curtis AE, Cooke JH, Jethwa PH, Todd JF, Ghatei MA, Bloom SR 2006 Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats. Am J Physiol Endocrinol Metab 291:E1074-E1082
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
-
-
Thompson, E.L.1
Murphy, K.G.2
Patterson, M.3
Bewick, G.A.4
Stamp, G.W.5
Curtis, A.E.6
Cooke, J.H.7
Jethwa, P.H.8
Todd, J.F.9
Ghatei, M.A.10
Bloom, S.R.11
-
7
-
-
33645884139
-
Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): A finding with therapeutic implications
-
Seminara SB, Dipietro MJ, Ramaswamy S, Crowley Jr WF, Plant TM 2006 Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): a finding with therapeutic implications. Endocrinology 147:2122-2126
-
(2006)
Endocrinology
, vol.147
, pp. 2122-2126
-
-
Seminara, S.B.1
Dipietro, M.J.2
Ramaswamy, S.3
Crowley Jr, W.F.4
Plant, T.M.5
-
8
-
-
34347252274
-
Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta)
-
Ramaswamy S, Seminara SB, Pohl CR, DiPietro MJ, Crowley Jr WF, Plant TM 2007 Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta). Endocrinology 148:3364-3370
-
(2007)
Endocrinology
, vol.148
, pp. 3364-3370
-
-
Ramaswamy, S.1
Seminara, S.B.2
Pohl, C.R.3
DiPietro, M.J.4
Crowley Jr, W.F.5
Plant, T.M.6
-
9
-
-
47549101608
-
Desensitization of gonadotropin responses to kisspeptin in the female rat: Analyses of LH and FSH secretion at different developmental and metabolic states
-
Roa J, Vigo E, Garcia-Galiano D, Castellano JM, Navarro VM, Pineda R, Diéguez C, Aguilar E, Pinilla L, Tena-Sempere M 2008 Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states. Am J Physiol Endocrinol Metab 294:E1088-E1096
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Roa, J.1
Vigo, E.2
Garcia-Galiano, D.3
Castellano, J.M.4
Navarro, V.M.5
Pineda, R.6
Diéguez, C.7
Aguilar, E.8
Pinilla, L.9
Tena-Sempere, M.10
-
10
-
-
0029719789
-
Desensitization of G protein-coupled receptors
-
discussion 352-353
-
Freedman NJ, Lefkowitz RJ 1996 Desensitization of G protein-coupled receptors. Recent Prog Horm Res 51:319-351; discussion 352-353
-
(1996)
Recent Prog Horm Res
, vol.51
, pp. 319-351
-
-
Freedman, N.J.1
Lefkowitz, R.J.2
-
11
-
-
0031747997
-
The role of receptor kinases and arrestins in G protein-coupled receptor regulation
-
Krupnick JG, Benovic JL 1998 The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38:289-319
-
(1998)
Annu Rev Pharmacol Toxicol
, vol.38
, pp. 289-319
-
-
Krupnick, J.G.1
Benovic, J.L.2
-
13
-
-
0036473397
-
The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals
-
Luttrell LM, Lefkowitz RJ 2002 The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci 115:455-465
-
(2002)
J Cell Sci
, vol.115
, pp. 455-465
-
-
Luttrell, L.M.1
Lefkowitz, R.J.2
-
14
-
-
40349093189
-
β-arrestins: Multifunctional cellular mediators
-
Barki-Harrington L, Rockman HA 2008 β-arrestins: multifunctional cellular mediators. Physiologist 23:17-22
-
(2008)
Physiologist
, vol.23
, pp. 17-22
-
-
Barki-Harrington, L.1
Rockman, H.A.2
-
15
-
-
0028558740
-
Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited
-
Subtil A, Hémar A, Dautry-Varsat A 1994 Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited. J Cell Sci 107:3461-3468
-
(1994)
J Cell Sci
, vol.107
, pp. 3461-3468
-
-
Subtil, A.1
Hémar, A.2
Dautry-Varsat, A.3
-
16
-
-
0038418651
-
Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: The initial fate of unbound E-cadherin
-
Paterson AD, Parton RG, Ferguson C, Stow JL, Yap AS 2003 Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin. J Biol Chem 278:21050-21057
-
(2003)
J Biol Chem
, vol.278
, pp. 21050-21057
-
-
Paterson, A.D.1
Parton, R.G.2
Ferguson, C.3
Stow, J.L.4
Yap, A.S.5
-
17
-
-
5444265165
-
Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis
-
Bhattacharya M, Babwah AV, Godin C, Anborgh PH, Dale LB, Poulter MO, Ferguson SS 2004 Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis. J Neurosci 24:8752-8761
-
(2004)
J Neurosci
, vol.24
, pp. 8752-8761
-
-
Bhattacharya, M.1
Babwah, A.V.2
Godin, C.3
Anborgh, P.H.4
Dale, L.B.5
Poulter, M.O.6
Ferguson, S.S.7
-
18
-
-
0037067705
-
Phosphorylation-independent regulation of metabotropic glutamate receptor signaling by G protein-coupled receptor kinase 2
-
Dhami GK, Anborgh PH, Dale LB, Sterne-Marr R, Ferguson SS 2002 Phosphorylation-independent regulation of metabotropic glutamate receptor signaling by G protein-coupled receptor kinase 2. J Biol Chem 277:25266-25272
-
(2002)
J Biol Chem
, vol.277
, pp. 25266-25272
-
-
Dhami, G.K.1
Anborgh, P.H.2
Dale, L.B.3
Sterne-Marr, R.4
Ferguson, S.S.5
-
19
-
-
67651151233
-
β-Arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells
-
Li TT, Alemayehu M, Aziziyeh AI, Pape C, Pampillo M, Postovit LM, Mills GB, Babwah AV, Bhattacharya M 2009 β-Arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Mol Cancer Res 7:1064-1077
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1064-1077
-
-
Li, T.T.1
Alemayehu, M.2
Aziziyeh, A.I.3
Pape, C.4
Pampillo, M.5
Postovit, L.M.6
Mills, G.B.7
Babwah, A.V.8
Bhattacharya, M.9
-
20
-
-
33646162635
-
GRKs and β-arrestins: Roles in receptor silencing, trafficking and signaling
-
Reiter E, Lefkowitz RJ 2006 GRKs and β-arrestins: roles in receptor silencing, trafficking and signaling. Trends Endocrinol Metab 17:159-165
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 159-165
-
-
Reiter, E.1
Lefkowitz, R.J.2
-
21
-
-
13544261496
-
Regulation of corticotropin-releasing hormone receptor type 1α signaling: Structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated desensitization
-
Teli T, Markovic D, Levine MA, Hillhouse EW, Grammatopoulos DK 2005 Regulation of corticotropin-releasing hormone receptor type 1α signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated desensitization. Mol Endocrinol 19:474-490
-
(2005)
Mol Endocrinol
, vol.19
, pp. 474-490
-
-
Teli, T.1
Markovic, D.2
Levine, M.A.3
Hillhouse, E.W.4
Grammatopoulos, D.K.5
-
22
-
-
0030609874
-
Synergistic regulation of β2-adrenergic receptor sequestration: Intracellular complement of β-adrenergic receptor kinase and β-arrestin determine kinetics of internalization
-
Ménard L, Ferguson SS, Zhang J, Lin FT, Lefkowitz RJ, Caron MG, Barak LS 1997 Synergistic regulation of β2-adrenergic receptor sequestration: intracellular complement of β-adrenergic receptor kinase and β-arrestin determine kinetics of internalization. Mol Pharmacol 51:800-808
-
(1997)
Mol Pharmacol
, vol.51
, pp. 800-808
-
-
Ménard, L.1
Ferguson, S.S.2
Zhang, J.3
Lin, F.T.4
Lefkowitz, R.J.5
Caron, M.G.6
Barak, L.S.7
-
23
-
-
0025279155
-
Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis
-
Mellon PL, Windle JJ, Goldsmith PC, Padula CA, Roberts JL, Weiner RI 1990 Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis. Neuron 5:1-10
-
(1990)
Neuron
, vol.5
, pp. 1-10
-
-
Mellon, P.L.1
Windle, J.J.2
Goldsmith, P.C.3
Padula, C.A.4
Roberts, J.L.5
Weiner, R.I.6
-
25
-
-
0027327733
-
Establishment and characterization of first trimester human trophoblast cells with extended lifespan
-
Graham CH, Hawley TS, Hawley RG, MacDougall JR, Kerbel RS, Khoo N, Lala PK 1993 Establishment and characterization of first trimester human trophoblast cells with extended lifespan. Exp Cell Res 206:204-211
-
(1993)
Exp Cell Res
, vol.206
, pp. 204-211
-
-
Graham, C.H.1
Hawley, T.S.2
Hawley, R.G.3
MacDougall, J.R.4
Kerbel, R.S.5
Khoo, N.6
Lala, P.K.7
-
26
-
-
67650095392
-
Gonadotropin-releasing hormone-regulated chemokine expression in human placentation
-
Cavanagh PC, Dunk C, Pampillo M, Szereszewski JM, Taylor JE, Kahiri C, Han V, Lye S, Bhattacharya M, Babwah AV 2009 Gonadotropin-releasing hormone-regulated chemokine expression in human placentation. Am J Physiol Cell Physiol 297:C17-C27
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Cavanagh, P.C.1
Dunk, C.2
Pampillo, M.3
Szereszewski, J.M.4
Taylor, J.E.5
Kahiri, C.6
Han, V.7
Lye, S.8
Bhattacharya, M.9
Babwah, A.V.10
-
27
-
-
36849039489
-
Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor
-
Holliday ND, Holst B, Rodionova EA, Schwartz TW, Cox HM 2007 Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor. Mol Endocrinol 21:3100-3112
-
(2007)
Mol Endocrinol
, vol.21
, pp. 3100-3112
-
-
Holliday, N.D.1
Holst, B.2
Rodionova, E.A.3
Schwartz, T.W.4
Cox, H.M.5
-
28
-
-
0842313243
-
Evolved regulation of gonadotropin-releasing hormone receptor cell surface expression
-
Janovick JA, Ulloa-Aguirre A, Conn PM 2003 Evolved regulation of gonadotropin-releasing hormone receptor cell surface expression. Endocrine 22:317-327
-
(2003)
Endocrine
, vol.22
, pp. 317-327
-
-
Janovick, J.A.1
Ulloa-Aguirre, A.2
Conn, P.M.3
-
29
-
-
0036206295
-
Regulation of RGS3 and RGS10 palmitoylation by GnRH
-
Castro-Fernández C, Janovick JA, Brothers SP, Fisher RA, Ji TH, Conn PM 2002 Regulation of RGS3 and RGS10 palmitoylation by GnRH. Endocrinology 143:1310-1317
-
(2002)
Endocrinology
, vol.143
, pp. 1310-1317
-
-
Castro-Fernández, C.1
Janovick, J.A.2
Brothers, S.P.3
Fisher, R.A.4
Ji, T.H.5
Conn, P.M.6
-
30
-
-
0033669923
-
The G-protein-coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic glutamate receptor 1
-
Sallese M, Salvatore L, D'Urbano E, Sala G, Storto M, Launey T, Nicoletti F, Knöpfel T, De Blasi A 2000 The G-protein-coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic glutamate receptor 1. FASEB J 14:2569-2580
-
(2000)
FASEB J
, vol.14
, pp. 2569-2580
-
-
Sallese, M.1
Salvatore, L.2
D'Urbano, E.3
Sala, G.4
Storto, M.5
Launey, T.6
Nicoletti, F.7
Knöpfel, T.8
De Blasi, A.9
-
31
-
-
0035213859
-
Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: Agonist-stimulated endocytosis is β-arrestin1 isoform-specific
-
Dale LB, Bhattacharya M, Seachrist JL, Anborgh PH, Ferguson SS 2001 Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: agonist-stimulated endocytosis is β-arrestin1 isoform-specific. Mol Pharmacol 60:1243-1253
-
(2001)
Mol Pharmacol
, vol.60
, pp. 1243-1253
-
-
Dale, L.B.1
Bhattacharya, M.2
Seachrist, J.L.3
Anborgh, P.H.4
Ferguson, S.S.5
-
32
-
-
0038146946
-
The metabotropic glutamate receptor mGluR5 is endocytosed by a clathrin-independent pathway
-
Fourgeaud L, Bessis AS, Rossignol F, Pin JP, Olivo-Marin JC, Hémar A 2003 The metabotropic glutamate receptor mGluR5 is endocytosed by a clathrin-independent pathway. J Biol Chem 278:12222-12230
-
(2003)
J Biol Chem
, vol.278
, pp. 12222-12230
-
-
Fourgeaud, L.1
Bessis, A.S.2
Rossignol, F.3
Pin, J.P.4
Olivo-Marin, J.C.5
Hémar, A.6
-
33
-
-
2542465774
-
Agonist-independent internalization of metabotropic glutamate receptor 1a is arrestinand clathrin-dependent and is suppressed by receptor inverse agonists
-
Pula G, Mundell SJ, Roberts PJ, Kelly E 2004 Agonist-independent internalization of metabotropic glutamate receptor 1a is arrestinand clathrin-dependent and is suppressed by receptor inverse agonists. J Neurochem 89:1009-1020
-
(2004)
J Neurochem
, vol.89
, pp. 1009-1020
-
-
Pula, G.1
Mundell, S.J.2
Roberts, P.J.3
Kelly, E.4
-
34
-
-
33847071711
-
The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): Its role in signaling and trafficking to the cell membrane
-
Kern A, Agoulnik AI, Bryant-Greenwood GD 2007 The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane. Endocrinology 148:1181-1194
-
(2007)
Endocrinology
, vol.148
, pp. 1181-1194
-
-
Kern, A.1
Agoulnik, A.I.2
Bryant-Greenwood, G.D.3
-
35
-
-
66449122003
-
Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells
-
Kern A, Bryant-Greenwood GD 2009 Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells. Endocrinology 150:2419-2428
-
(2009)
Endocrinology
, vol.150
, pp. 2419-2428
-
-
Kern, A.1
Bryant-Greenwood, G.D.2
-
36
-
-
15744366592
-
Structure/function analysis of alpha2Aadrenergic receptor interaction with G protein-coupled receptor kinase 2
-
Pao CS, Benovic JL 2005 Structure/function analysis of alpha2Aadrenergic receptor interaction with G protein-coupled receptor kinase 2. J Biol Chem 280:11052-11058
-
(2005)
J Biol Chem
, vol.280
, pp. 11052-11058
-
-
Pao, C.S.1
Benovic, J.L.2
-
37
-
-
21644483602
-
Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires G protein-coupled receptor kinase 2 binding to the second intracellular loop
-
Dhami GK, Babwah AV, Sterne-Marr R, Ferguson SS 2005 Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires G protein-coupled receptor kinase 2 binding to the second intracellular loop. J Biol Chem 280:24420-24427
-
(2005)
J Biol Chem
, vol.280
, pp. 24420-24427
-
-
Dhami, G.K.1
Babwah, A.V.2
Sterne-Marr, R.3
Ferguson, S.S.4
-
38
-
-
0033607326
-
Selective regulation of Galpha(q/11) by an RGS domain in theGproteincoupled receptor kinase, GRK2
-
Carman CV, Parent JL, Day PW, Pronin AN, Sternweis PM, Wedegaertner PB, Gilman AG, Benovic JL, Kozasa T 1999 Selective regulation of Galpha(q/11) by an RGS domain in theGproteincoupled receptor kinase, GRK2. J Biol Chem 274:34483-34492
-
(1999)
J Biol Chem
, vol.274
, pp. 34483-34492
-
-
Carman, C.V.1
Parent, J.L.2
Day, P.W.3
Pronin, A.N.4
Sternweis, P.M.5
Wedegaertner, P.B.6
Gilman, A.G.7
Benovic, J.L.8
Kozasa, T.9
-
39
-
-
57649165543
-
Disease-causing mutation in GPR54 reveals the importance of the second intracellular loop for class A G-protein-coupled receptor function
-
Wacker JL, Feller DB, Tang XB, Defino MC, Namkung Y, Lyssand JS, Mhyre AJ, Tan X, Jensen JB, Hague C 2008 Disease-causing mutation in GPR54 reveals the importance of the second intracellular loop for class A G-protein-coupled receptor function. J Biol Chem 283:31068-31078
-
(2008)
J Biol Chem
, vol.283
, pp. 31068-31078
-
-
Wacker, J.L.1
Feller, D.B.2
Tang, X.B.3
Defino, M.C.4
Namkung, Y.5
Lyssand, J.S.6
Mhyre, A.J.7
Tan, X.8
Jensen, J.B.9
Hague, C.10
-
40
-
-
1942501582
-
G Protein-coupled receptor kinase 2 regulator of G protein signaling homology domain binds to both metabotropic glutamate receptor 1a and Gαq to attenuate signaling
-
Dhami GK, Dale LB, Anborgh PH, O'Connor-Halligan KE, Sterne-Marr R, Ferguson SS 2004 G Protein-coupled receptor kinase 2 regulator of G protein signaling homology domain binds to both metabotropic glutamate receptor 1a and Gαq to attenuate signaling. J Biol Chem 279:16614-16620
-
(2004)
J Biol Chem
, vol.279
, pp. 16614-16620
-
-
Dhami, G.K.1
Dale, L.B.2
Anborgh, P.H.3
O'Connor-Halligan, K.E.4
Sterne-Marr, R.5
Ferguson, S.S.6
-
41
-
-
34249824302
-
Functional desensitization of the extracellular calcium-sensing receptor is regulated via distinctmechanisms:role ofGprotein-coupled receptor kinases, protein kinase C and β-arrestins
-
Lorenz S, Frenzel R, Paschke R, Breitwieser GE, Miedlich SU 2007 Functional desensitization of the extracellular calcium-sensing receptor is regulated via distinctmechanisms:role ofGprotein-coupled receptor kinases, protein kinase C and β-arrestins. Endocrinology 148:2398-2404
-
(2007)
Endocrinology
, vol.148
, pp. 2398-2404
-
-
Lorenz, S.1
Frenzel, R.2
Paschke, R.3
Breitwieser, G.E.4
Miedlich, S.U.5
-
42
-
-
0030020424
-
Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases
-
Tiberi M, Nash SR, Bertrand L, Lefkowitz RJ, Caron MG 1996 Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases. J Biol Chem 271:3771-3778
-
(1996)
J Biol Chem
, vol.271
, pp. 3771-3778
-
-
Tiberi, M.1
Nash, S.R.2
Bertrand, L.3
Lefkowitz, R.J.4
Caron, M.G.5
-
43
-
-
0033391143
-
Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice
-
Gainetdinov RR, Bohn LM, Walker JK, Laporte SA, Macrae AD, Caron MG, Lefkowitz RJ, Premont RT 1999 Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice. Neuron 24:1029-1036
-
(1999)
Neuron
, vol.24
, pp. 1029-1036
-
-
Gainetdinov, R.R.1
Bohn, L.M.2
Walker, J.K.3
Laporte, S.A.4
Macrae, A.D.5
Caron, M.G.6
Lefkowitz, R.J.7
Premont, R.T.8
-
44
-
-
0034283786
-
Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors
-
Aiyar N, Disa J, Dang K, Pronin AN, Benovic JL, Nambi P 2000 Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors. Eur J Pharmacol 403:1-7
-
(2000)
Eur J Pharmacol
, vol.403
, pp. 1-7
-
-
Aiyar, N.1
Disa, J.2
Dang, K.3
Pronin, A.N.4
Benovic, J.L.5
Nambi, P.6
-
45
-
-
0037013186
-
Endogenous G protein coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells
-
Willets JM, Challiss RA, Nahorski SR 2002 Endogenous G protein coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells. J Biol Chem 277:15523-15529
-
(2002)
J Biol Chem
, vol.277
, pp. 15523-15529
-
-
Willets, J.M.1
Challiss, R.A.2
Nahorski, S.R.3
-
46
-
-
33847081648
-
Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity
-
Smit MJ, Vischer HF, Bakker RA, Jongejan A, Timmerman H, Pardo L, Leurs R 2007 Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity. Annu Rev Pharmacol Toxicol 47:53-87
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 53-87
-
-
Smit, M.J.1
Vischer, H.F.2
Bakker, R.A.3
Jongejan, A.4
Timmerman, H.5
Pardo, L.6
Leurs, R.7
-
47
-
-
34748900269
-
Kiss1-/-mice exhibit more variable hypogonadism than Gpr54-/- mice
-
Lapatto R, Pallais JC, Zhang D, Chan YM, Mahan A, Cerrato F, Le WW, Hoffman GE, Seminara SB 2007 Kiss1-/-mice exhibit more variable hypogonadism than Gpr54-/- mice. Endocrinology 148: 4927-4936
-
(2007)
Endocrinology
, vol.148
, pp. 4927-4936
-
-
Lapatto, R.1
Pallais, J.C.2
Zhang, D.3
Chan, Y.M.4
Mahan, A.5
Cerrato, F.6
Le, W.W.7
Hoffman, G.E.8
Seminara, S.B.9
-
48
-
-
4344646417
-
Constitutive desensitization: A new paradigm for g protein-coupled receptor regulation
-
Barak LS, Wilbanks AM, Caron MG 2003 Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation. Assay Drug Dev Technol 1:339-346
-
(2003)
Assay Drug Dev Technol
, vol.1
, pp. 339-346
-
-
Barak, L.S.1
Wilbanks, A.M.2
Caron, M.G.3
-
49
-
-
33646365380
-
A β-arrestin binding determinant common to the second intracellular loops of rhodopsin familyGprotein-coupled receptors
-
Marion S, Oakley RH, Kim KM, Caron MG, Barak LS 2006 A β-arrestin binding determinant common to the second intracellular loops of rhodopsin familyGprotein-coupled receptors. J Biol Chem 281:2932-2938
-
(2006)
J Biol Chem
, vol.281
, pp. 2932-2938
-
-
Marion, S.1
Oakley, R.H.2
Kim, K.M.3
Caron, M.G.4
Barak, L.S.5
-
50
-
-
14244262888
-
Phosphorylation-independent β-arrestin translocation and internalization of leukotriene B4 receptors
-
Jala VR, Shao WH, Haribabu B 2005 Phosphorylation-independent β-arrestin translocation and internalization of leukotriene B4 receptors. J Biol Chem 280:4880-4887
-
(2005)
J Biol Chem
, vol.280
, pp. 4880-4887
-
-
Jala, V.R.1
Shao, W.H.2
Haribabu, B.3
-
51
-
-
34447622268
-
Carboxyl-terminal and intracellular loop sites for CRF1 receptor phosphorylation and β-arrestin-2 recruitment: A mechanism regulating stress and anxiety responses
-
Oakley RH, Olivares-Reyes JA, Hudson CC, Flores-Vega F, Dautzenberg FM, Hauger RL 2007 Carboxyl-terminal and intracellular loop sites for CRF1 receptor phosphorylation and β-arrestin-2 recruitment: a mechanism regulating stress and anxiety responses. Am J Physiol Regul Integr Comp Physiol 293:R209-R322
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
-
-
Oakley, R.H.1
Olivares-Reyes, J.A.2
Hudson, C.C.3
Flores-Vega, F.4
Dautzenberg, F.M.5
Hauger, R.L.6
-
52
-
-
0035852697
-
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
-
Kohout TA, Lin FS, Perry SJ, Conner DA, Lefkowitz RJ 2001 β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc Natl Acad Sci USA 98:1601-1606
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1601-1606
-
-
Kohout, T.A.1
Lin, F.S.2
Perry, S.J.3
Conner, D.A.4
Lefkowitz, R.J.5
-
53
-
-
0034463035
-
The rat gonadotropin-releasing hormone receptor internalizes via a β-arrestin-independent, but dynamin-dependent, pathway: Addition of a carboxyl-terminal tail confers β-arrestin dependency
-
Heding A, Vrecl M, Hanyaloglu AC, Sellar R, Taylor PL, Eidne KA 2000 The rat gonadotropin-releasing hormone receptor internalizes via a β-arrestin-independent, but dynamin-dependent, pathway: addition of a carboxyl-terminal tail confers β-arrestin dependency. Endocrinology 141:299-306
-
(2000)
Endocrinology
, vol.141
, pp. 299-306
-
-
Heding, A.1
Vrecl, M.2
Hanyaloglu, A.C.3
Sellar, R.4
Taylor, P.L.5
Eidne, K.A.6
-
54
-
-
33645970198
-
Regulation of N-formyl peptide receptor signaling and trafficking by individual carboxyl-terminal serine and threonine residues
-
Potter RM, Maestas DC, Cimino DF, Prossnitz ER 2006 Regulation of N-formyl peptide receptor signaling and trafficking by individual carboxyl-terminal serine and threonine residues. J Immunol 176:5418-5425
-
(2006)
J Immunol
, vol.176
, pp. 5418-5425
-
-
Potter, R.M.1
Maestas, D.C.2
Cimino, D.F.3
Prossnitz, E.R.4
-
55
-
-
0037044843
-
The third intracellular loop of β 2-adrenergic receptors determines subtype specificity of arrestin interaction
-
DeGraff JL, Gurevich VV, Benovic JL 2002 The third intracellular loop of β 2-adrenergic receptors determines subtype specificity of arrestin interaction. J Biol Chem 277:43247-43252
-
(2002)
J Biol Chem
, vol.277
, pp. 43247-43252
-
-
DeGraff, J.L.1
Gurevich, V.V.2
Benovic, J.L.3
-
56
-
-
0033527663
-
Association of β-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
-
Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG 1999 Association of β-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem 274:32248-32257
-
(1999)
J Biol Chem
, vol.274
, pp. 32248-32257
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Barak, L.S.4
Caron, M.G.5
-
57
-
-
0034595860
-
Differential affinities of visual arrestin, β arrestin1, and β arrestin2 for G protein-coupled receptors delineate two major classes of receptors
-
Oakley RH, Laporte SA, Holt JA, Caron MG, Barak LS 2000 Differential affinities of visual arrestin, β arrestin1, and β arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J Biol Chem 275:17201-17210
-
(2000)
J Biol Chem
, vol.275
, pp. 17201-17210
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
Caron, M.G.4
Barak, L.S.5
-
58
-
-
73249122007
-
Expression of GPR54 and KiSS1 in human breast cancer
-
Washington, DC, Abstract 1013-c-1014
-
Prentice LM, Miller MA, Turbin DA, Aparicio SAJR, Huntsman DG, Expression of GPR54 and KiSS1 in human breast cancer. Proc 97th Annual Meeting of the American Association for Cancer Research, Washington, DC, 2006 (Abstract 1013-c-1014)
-
(2006)
Proc 97th Annual Meeting of the American Association for Cancer Research
-
-
Prentice, L.M.1
Miller, M.A.2
Turbin, D.A.3
Aparicio, S.A.J.R.4
Huntsman, D.G.5
-
59
-
-
0033613938
-
β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes
-
Luttrell LM, Ferguson SS, Daaka Y, Miller WE, Maudsley S, Della Rocca GJ, Lin F, Kawakatsu H, Owada K, Luttrell DK, Caron MG, Lefkowitz RJ 1999 β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes. Science 283:655-661
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
Ferguson, S.S.2
Daaka, Y.3
Miller, W.E.4
Maudsley, S.5
Della Rocca, G.J.6
Lin, F.7
Kawakatsu, H.8
Owada, K.9
Luttrell, D.K.10
Caron, M.G.11
Lefkowitz, R.J.12
-
60
-
-
28744448385
-
Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males
-
Dhillo WS, Chaudhri OB, Patterson M, Thompson EL, Murphy KG, Badman MK, McGowan BM, Amber V, Patel S, Ghatei MA, Bloom SR 2005 Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. J Clin Endocrinol Metab 90: 6609-6615
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 6609-6615
-
-
Dhillo, W.S.1
Chaudhri, O.B.2
Patterson, M.3
Thompson, E.L.4
Murphy, K.G.5
Badman, M.K.6
McGowan, B.M.7
Amber, V.8
Patel, S.9
Ghatei, M.A.10
Bloom, S.R.11
-
61
-
-
39049168719
-
A GPR54-activating mutation in a patient with central precocious puberty
-
Teles MG, Bianco SD, Brito VN, Trarbach EB, Kuohung W, Xu S, Seminara SB, Mendonca BB, Kaiser UB, Latronico AC 2008 A GPR54-activating mutation in a patient with central precocious puberty. N Engl J Med 358:709-715
-
(2008)
N Engl J Med
, vol.358
, pp. 709-715
-
-
Teles, M.G.1
Bianco, S.D.2
Brito, V.N.3
Trarbach, E.B.4
Kuohung, W.5
Xu, S.6
Seminara, S.B.7
Mendonca, B.B.8
Kaiser, U.B.9
Latronico, A.C.10
|