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Volumn 31, Issue 44, 2013, Pages 5088-5098

HIV-derived lentiviral particles promote T-cell independent activation and differentiation of naïve cognate conventional B2-cells in vitro

Author keywords

B cells; Lentiviral VLP; T independent activation

Indexed keywords

CD38 ANTIGEN; CD40 LIGAND; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN ALLOTYPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G3; L SELECTIN; LYSOZYME; SYNDECAN 1; VIRUS LIKE PARTICLE VACCINE;

EID: 84885434723     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.08.055     Document Type: Article
Times cited : (14)

References (46)
  • 1
    • 33748794562 scopus 로고    scopus 로고
    • Virus-like particles: passport to immune recognition
    • Grgacic E.V., Anderson D.A. Virus-like particles: passport to immune recognition. Methods 2006, 40:60-65.
    • (2006) Methods , vol.40 , pp. 60-65
    • Grgacic, E.V.1    Anderson, D.A.2
  • 3
    • 84870540478 scopus 로고    scopus 로고
    • Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development
    • Kushnir N., Streatfield S.J., Yusibov V. Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development. Vaccine 2012, 31:58-63.
    • (2012) Vaccine , vol.31 , pp. 58-63
    • Kushnir, N.1    Streatfield, S.J.2    Yusibov, V.3
  • 4
    • 33846420615 scopus 로고    scopus 로고
    • Membrane embedded HIV-1 envelope on the surface of a virus-like particle elicits broader immune responses than soluble envelopes
    • McBurney S.P., Young K.R., Ross T.M. Membrane embedded HIV-1 envelope on the surface of a virus-like particle elicits broader immune responses than soluble envelopes. Virology 2007, 358:334-346.
    • (2007) Virology , vol.358 , pp. 334-346
    • McBurney, S.P.1    Young, K.R.2    Ross, T.M.3
  • 5
    • 84860799382 scopus 로고    scopus 로고
    • T cell independent secondary antibody responses to the envelope protein of simian immunodeficiency virus
    • Nabi G., Temchura V., Grossmann C., Kuate S., Tenbusch M., Überla K. T cell independent secondary antibody responses to the envelope protein of simian immunodeficiency virus. Retrovirology 2012, 9:42.
    • (2012) Retrovirology , vol.9 , pp. 42
    • Nabi, G.1    Temchura, V.2    Grossmann, C.3    Kuate, S.4    Tenbusch, M.5    Überla, K.6
  • 6
    • 33745863446 scopus 로고    scopus 로고
    • Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus
    • Kuate S., Stahl-Hennig C., Stoiber H., Nchinda G., Floto A., Franz M., et al. Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus. Virology 2006, 351:133-144.
    • (2006) Virology , vol.351 , pp. 133-144
    • Kuate, S.1    Stahl-Hennig, C.2    Stoiber, H.3    Nchinda, G.4    Floto, A.5    Franz, M.6
  • 7
    • 84868157389 scopus 로고    scopus 로고
    • Risk of immunodeficiency virus infection may increase with vaccine-induced immune response
    • Tenbusch M., Ignatius R., Temchura V., Nabi G., Tippler B., Stewart-Jones G., et al. Risk of immunodeficiency virus infection may increase with vaccine-induced immune response. J Virol 2012, 86:10533-10539.
    • (2012) J Virol , vol.86 , pp. 10533-10539
    • Tenbusch, M.1    Ignatius, R.2    Temchura, V.3    Nabi, G.4    Tippler, B.5    Stewart-Jones, G.6
  • 8
    • 63649120342 scopus 로고    scopus 로고
    • Virus-like particle (VLP) lymphatic trafficking and immune response generation after immunization by different routes
    • Cubas R., Zhang S., Kwon S., Sevick-Muraca E.M., Li M., Chen C., et al. Virus-like particle (VLP) lymphatic trafficking and immune response generation after immunization by different routes. J Immunother 2009, 32:118-128.
    • (2009) J Immunother , vol.32 , pp. 118-128
    • Cubas, R.1    Zhang, S.2    Kwon, S.3    Sevick-Muraca, E.M.4    Li, M.5    Chen, C.6
  • 9
    • 0031949857 scopus 로고    scopus 로고
    • T-cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus-like particles
    • Szomolanyi-Tsuda E., Le Q.P., Garcea R.L., Welsh R.M. T-cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus-like particles. J Virol 1998, 72:6665-6670.
    • (1998) J Virol , vol.72 , pp. 6665-6670
    • Szomolanyi-Tsuda, E.1    Le, Q.P.2    Garcea, R.L.3    Welsh, R.M.4
  • 10
    • 84869049199 scopus 로고    scopus 로고
    • Long-term and memory immune responses in mice against Newcastle disease virus-like particles containing respiratory syncytial virus glycoprotein ectodomains
    • Schmidt M.R., McGinnes L.W., Kenward S.A., Willems K.N., Woodland R.T., Morrison T.G. Long-term and memory immune responses in mice against Newcastle disease virus-like particles containing respiratory syncytial virus glycoprotein ectodomains. J Virol 2012, 86:11654-11662.
    • (2012) J Virol , vol.86 , pp. 11654-11662
    • Schmidt, M.R.1    McGinnes, L.W.2    Kenward, S.A.3    Willems, K.N.4    Woodland, R.T.5    Morrison, T.G.6
  • 11
    • 3242743547 scopus 로고    scopus 로고
    • Th cell-independent immune responses to chimeric hemagglutinin/simian human immunodeficiency virus-like particles vaccine
    • Yao Q., Zhang R., Guo L., Li M., Chen C. Th cell-independent immune responses to chimeric hemagglutinin/simian human immunodeficiency virus-like particles vaccine. J Immunol 2004, 173:1951-1958.
    • (2004) J Immunol , vol.173 , pp. 1951-1958
    • Yao, Q.1    Zhang, R.2    Guo, L.3    Li, M.4    Chen, C.5
  • 12
    • 0031927461 scopus 로고    scopus 로고
    • T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses
    • Fehr T., Naim H.Y., Bachmann M.F., Ochsenbein A.F., Spielhofer P., Bucher E., et al. T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses. Nat Med 1998, 4:945-948.
    • (1998) Nat Med , vol.4 , pp. 945-948
    • Fehr, T.1    Naim, H.Y.2    Bachmann, M.F.3    Ochsenbein, A.F.4    Spielhofer, P.5    Bucher, E.6
  • 13
    • 5444268171 scopus 로고    scopus 로고
    • Recombinant HIV-1 Pr55gag virus-like particles: potent stimulators of innate and acquired immune responses
    • Deml L., Speth C., Dierich M.P., Wolf H., Wagner R. Recombinant HIV-1 Pr55gag virus-like particles: potent stimulators of innate and acquired immune responses. Mol Immunol 2005, 42:259-277.
    • (2005) Mol Immunol , vol.42 , pp. 259-277
    • Deml, L.1    Speth, C.2    Dierich, M.P.3    Wolf, H.4    Wagner, R.5
  • 14
    • 0036732753 scopus 로고    scopus 로고
    • DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
    • Litinskiy M.B., Nardell B., Hilbert D.M., He B., Schaffer A., Casali P., et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 2002, 3:822-829.
    • (2002) Nat Immunol , vol.3 , pp. 822-829
    • Litinskiy, M.B.1    Nardell, B.2    Hilbert, D.M.3    He, B.4    Schaffer, A.5    Casali, P.6
  • 15
    • 0036754302 scopus 로고    scopus 로고
    • Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses
    • Balázs M., Martin F., Zhou T., Kearney J. Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 2002, 17:341-352.
    • (2002) Immunity , vol.17 , pp. 341-352
    • Balázs, M.1    Martin, F.2    Zhou, T.3    Kearney, J.4
  • 16
    • 0034053268 scopus 로고    scopus 로고
    • Dendritic cell-B-cell interaction: dendritic cells provide B cells with CD40-independent proliferation signals and CD40-dependent survival signals
    • Wykes M., MacPherson G. Dendritic cell-B-cell interaction: dendritic cells provide B cells with CD40-independent proliferation signals and CD40-dependent survival signals. Immunology 2000, 100:1-3.
    • (2000) Immunology , vol.100 , pp. 1-3
    • Wykes, M.1    MacPherson, G.2
  • 17
    • 20444413835 scopus 로고    scopus 로고
    • B lymphocyte activation by human papillomavirus-like particles directly induces Ig class switch recombination via TLR4-MyD88
    • Yang R., Murillo F.M., Delannoy M.J., Blosser R.L., Yutzy W.H., Uematsu S., et al. B lymphocyte activation by human papillomavirus-like particles directly induces Ig class switch recombination via TLR4-MyD88. J Immunol 2005, 174:7912-7919.
    • (2005) J Immunol , vol.174 , pp. 7912-7919
    • Yang, R.1    Murillo, F.M.2    Delannoy, M.J.3    Blosser, R.L.4    Yutzy, W.H.5    Uematsu, S.6
  • 18
    • 67349209319 scopus 로고    scopus 로고
    • Virus-like particle vaccine activates conventional B2 cells and promotes B cell differentiation to IgG2a producing plasma cells
    • Zhang S., Cubas R., Li M., Chen C., Yao Q. Virus-like particle vaccine activates conventional B2 cells and promotes B cell differentiation to IgG2a producing plasma cells. Mol Immunol 2009, 46:1988-2001.
    • (2009) Mol Immunol , vol.46 , pp. 1988-2001
    • Zhang, S.1    Cubas, R.2    Li, M.3    Chen, C.4    Yao, Q.5
  • 19
    • 0037390660 scopus 로고    scopus 로고
    • B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells
    • Phan T.G., Amesbury M., Gardam S., Crosbie J., Hasbold J., Hodgkin P.D., et al. B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells. J Exp Med 2003, 197:845-860.
    • (2003) J Exp Med , vol.197 , pp. 845-860
    • Phan, T.G.1    Amesbury, M.2    Gardam, S.3    Crosbie, J.4    Hasbold, J.5    Hodgkin, P.D.6
  • 20
    • 0023018742 scopus 로고
    • Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain
    • Miller J., Germain R.N. Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain. J Exp Med 1986, 164:1478-1489.
    • (1986) J Exp Med , vol.164 , pp. 1478-1489
    • Miller, J.1    Germain, R.N.2
  • 21
    • 0034694017 scopus 로고    scopus 로고
    • Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: Implications for the safety of lentiviral vectors
    • Wagner R., Graf M., Bieler K., Wolf H., Grunwald T., Foley P., et al. Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: Implications for the safety of lentiviral vectors. Hum Gene Ther 2000, 11:2403-2413.
    • (2000) Hum Gene Ther , vol.11 , pp. 2403-2413
    • Wagner, R.1    Graf, M.2    Bieler, K.3    Wolf, H.4    Grunwald, T.5    Foley, P.6
  • 22
    • 45049087024 scopus 로고    scopus 로고
    • Enhancement of immunostimulatory properties of exosomal vaccines by incorporation of fusion-competent G protein of vesicular stomatitis virus
    • Temchura V.V., Tenbusch M., Nchinda G., Nabi G., Tippler B., Zelenyuk M., et al. Enhancement of immunostimulatory properties of exosomal vaccines by incorporation of fusion-competent G protein of vesicular stomatitis virus. Vaccine 2008, 26:3662-3672.
    • (2008) Vaccine , vol.26 , pp. 3662-3672
    • Temchura, V.V.1    Tenbusch, M.2    Nchinda, G.3    Nabi, G.4    Tippler, B.5    Zelenyuk, M.6
  • 23
    • 0026447940 scopus 로고
    • Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression
    • Schwartz S., Campbel M., Nasioulas G., Harrison J., Felber B.K., Pavlakis G.N. Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression. J Virol 1992, 66:7176-7182.
    • (1992) J Virol , vol.66 , pp. 7176-7182
    • Schwartz, S.1    Campbel, M.2    Nasioulas, G.3    Harrison, J.4    Felber, B.K.5    Pavlakis, G.N.6
  • 24
    • 84861581031 scopus 로고    scopus 로고
    • Targeting antibody responses to the membrane proximal external region of the envelope glycoprotein of human immunodeficiency virus
    • Kamdem Toukam D., Tenbusch M., Stang A., Temchura V., Storcksdieck Genannt Bonsmann M., Grewe B., et al. Targeting antibody responses to the membrane proximal external region of the envelope glycoprotein of human immunodeficiency virus. PLoS One 2012, 7:e38068. 10.1371/journal.pone.0038068.
    • (2012) PLoS One , vol.7
    • Kamdem Toukam, D.1    Tenbusch, M.2    Stang, A.3    Temchura, V.4    Storcksdieck Genannt Bonsmann, M.5    Grewe, B.6
  • 25
    • 84857947884 scopus 로고    scopus 로고
    • Cytoplasmic utilization of human immunodeficiency virus type 1 genomic RNA is not dependent on a nuclear interaction with gag
    • Grewe B., Hoffmann B., Ohs I., Blissenbach M., Brandt S., Tippler B., et al. Cytoplasmic utilization of human immunodeficiency virus type 1 genomic RNA is not dependent on a nuclear interaction with gag. J Virol 2012, 86:2990-3002.
    • (2012) J Virol , vol.86 , pp. 2990-3002
    • Grewe, B.1    Hoffmann, B.2    Ohs, I.3    Blissenbach, M.4    Brandt, S.5    Tippler, B.6
  • 26
    • 13544259968 scopus 로고    scopus 로고
    • B cell selection and susceptibility to autoimmunity
    • Grimaldi C.M., Hicks R., Diamond B. B cell selection and susceptibility to autoimmunity. J Immunol 2005, 174:1775-1781.
    • (2005) J Immunol , vol.174 , pp. 1775-1781
    • Grimaldi, C.M.1    Hicks, R.2    Diamond, B.3
  • 27
    • 0036884819 scopus 로고    scopus 로고
    • Regulation of B-cell fate by antigen-receptor signals
    • Niiro H., Clark E.A. Regulation of B-cell fate by antigen-receptor signals. Nat Rev Immunol 2002, 2:945-956.
    • (2002) Nat Rev Immunol , vol.2 , pp. 945-956
    • Niiro, H.1    Clark, E.A.2
  • 28
    • 0027324869 scopus 로고
    • Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells
    • Laszlo G., Hathcock K.S., Dickle H.B., Hodes R.J. Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells. J Immunol 1993, 150:5252-5262.
    • (1993) J Immunol , vol.150 , pp. 5252-5262
    • Laszlo, G.1    Hathcock, K.S.2    Dickle, H.B.3    Hodes, R.J.4
  • 29
    • 79956079578 scopus 로고    scopus 로고
    • Germinal center B and follicular helper T cells: siblings, cousins or just good friends
    • Nutt S.L., Tarlinton D.M. Germinal center B and follicular helper T cells: siblings, cousins or just good friends. Nat Immunol 2011, 12:472-477.
    • (2011) Nat Immunol , vol.12 , pp. 472-477
    • Nutt, S.L.1    Tarlinton, D.M.2
  • 30
    • 0031066609 scopus 로고    scopus 로고
    • Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells
    • Oliver A.M., Martin F., Kearney J.F. Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells. J Immunol 1997, 158:1108-1115.
    • (1997) J Immunol , vol.158 , pp. 1108-1115
    • Oliver, A.M.1    Martin, F.2    Kearney, J.F.3
  • 31
    • 57649233027 scopus 로고    scopus 로고
    • Germinal centre and marginal zone B cells expand quickly in a second Plasmodium chabaudi malaria infection producing mature plasma cells
    • Stephens R., Ndungu F.M., Langhorne J. Germinal centre and marginal zone B cells expand quickly in a second Plasmodium chabaudi malaria infection producing mature plasma cells. Parasite Immunol 2009, 31:20-31.
    • (2009) Parasite Immunol , vol.31 , pp. 20-31
    • Stephens, R.1    Ndungu, F.M.2    Langhorne, J.3
  • 32
    • 82255181371 scopus 로고    scopus 로고
    • Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts
    • Marshall J.L., Zhang Y., Pallan L., Hsu M.C., Khan M., Cunningham A.F., et al. Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts. Eur J Immunol 2011, 41:3506-3512.
    • (2011) Eur J Immunol , vol.41 , pp. 3506-3512
    • Marshall, J.L.1    Zhang, Y.2    Pallan, L.3    Hsu, M.C.4    Khan, M.5    Cunningham, A.F.6
  • 33
    • 79952699980 scopus 로고    scopus 로고
    • AID expression during B-cell development: searching for answers
    • Kuraoka M., McWilliams L., Kelsoe G. AID expression during B-cell development: searching for answers. Immunol Res 2011, 49:3-13.
    • (2011) Immunol Res , vol.49 , pp. 3-13
    • Kuraoka, M.1    McWilliams, L.2    Kelsoe, G.3
  • 34
    • 0032213363 scopus 로고    scopus 로고
    • Role of T cells and germinal center formation in the generation of immune responses to the thymus-independent carbohydrate dextran B512
    • Sverremark E., Fernandez C. Role of T cells and germinal center formation in the generation of immune responses to the thymus-independent carbohydrate dextran B512. J Immunol 1998, 161:4646-4651.
    • (1998) J Immunol , vol.161 , pp. 4646-4651
    • Sverremark, E.1    Fernandez, C.2
  • 36
    • 0031937064 scopus 로고    scopus 로고
    • Regulation of cytoplasmic, surface and soluble forms of CD40 ligand in mouse B cells
    • Wykes M., Poudrier J., Lindstedt R., Gray D. Regulation of cytoplasmic, surface and soluble forms of CD40 ligand in mouse B cells. Eur J Immunol 1998, 28:548-559.
    • (1998) Eur J Immunol , vol.28 , pp. 548-559
    • Wykes, M.1    Poudrier, J.2    Lindstedt, R.3    Gray, D.4
  • 37
    • 44449151190 scopus 로고    scopus 로고
    • Virus-like display of a neo-self antigen reverses B cell anergy in a B cell receptor transgenic mouse model
    • Chackerian B., Durfee M.R., Schiller J.T. Virus-like display of a neo-self antigen reverses B cell anergy in a B cell receptor transgenic mouse model. J Immunol 2008, 180:5816-5825.
    • (2008) J Immunol , vol.180 , pp. 5816-5825
    • Chackerian, B.1    Durfee, M.R.2    Schiller, J.T.3
  • 38
    • 78049368900 scopus 로고    scopus 로고
    • TLR-mediated loss of CD62L focuses B cell traffic to the spleen during Salmonella typhimurium infection
    • Morrison V.L., Bar T.A., Brown S., Gray D. TLR-mediated loss of CD62L focuses B cell traffic to the spleen during Salmonella typhimurium infection. J Immunol 2010, 185:2737-2746.
    • (2010) J Immunol , vol.185 , pp. 2737-2746
    • Morrison, V.L.1    Bar, T.A.2    Brown, S.3    Gray, D.4
  • 39
    • 34250192856 scopus 로고    scopus 로고
    • TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses
    • Genestier L., Taillardet M., Mondiere P., Gheit H., Bella C., Defrance T. TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses. J Immunol 2007, 178:7779-7786.
    • (2007) J Immunol , vol.178 , pp. 7779-7786
    • Genestier, L.1    Taillardet, M.2    Mondiere, P.3    Gheit, H.4    Bella, C.5    Defrance, T.6
  • 40
    • 0028298229 scopus 로고
    • Gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory
    • Foy T.M., Laman J.D., Ledbetter J.A., Aruffo A., Claassen E., Noelle R.J. gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. J Exp Med 1994, 180:157-163.
    • (1994) J Exp Med , vol.180 , pp. 157-163
    • Foy, T.M.1    Laman, J.D.2    Ledbetter, J.A.3    Aruffo, A.4    Claassen, E.5    Noelle, R.J.6
  • 41
    • 33749021665 scopus 로고    scopus 로고
    • B-cell memory: are subsets necessary
    • Tarlinton D. B-cell memory: are subsets necessary. Nat Rev Immunol 2006, 6:785-790.
    • (2006) Nat Rev Immunol , vol.6 , pp. 785-790
    • Tarlinton, D.1
  • 42
    • 78650647005 scopus 로고    scopus 로고
    • Cutting edge: hierarchy of maturity of murine memory B cell subsets
    • Tomayko M.M., Steinel N.C., Anderson S.M., Shlomchik M.J. Cutting edge: hierarchy of maturity of murine memory B cell subsets. J Immunol 2010, 185:7146-7150.
    • (2010) J Immunol , vol.185 , pp. 7146-7150
    • Tomayko, M.M.1    Steinel, N.C.2    Anderson, S.M.3    Shlomchik, M.J.4
  • 44
    • 77958487137 scopus 로고    scopus 로고
    • Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics
    • Good-Jacobson K.L., Shlomchik M.J. Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics. J Immunol 2010, 185:3117-3125.
    • (2010) J Immunol , vol.185 , pp. 3117-3125
    • Good-Jacobson, K.L.1    Shlomchik, M.J.2
  • 45
    • 34548237299 scopus 로고    scopus 로고
    • A signalling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma
    • Saito M., Gao J., Basso K., Kitagawa Y., Smith P.M., Bhagat G., et al. A signalling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer Cell 2007, 12:280-292.
    • (2007) Cancer Cell , vol.12 , pp. 280-292
    • Saito, M.1    Gao, J.2    Basso, K.3    Kitagawa, Y.4    Smith, P.M.5    Bhagat, G.6
  • 46
    • 0028845408 scopus 로고
    • Selective increases in antibody isotypes and immunoglobulin G subclass responses to secreted antigens in tuberculosis patients and healthy household contacts of the patients
    • Hussain R., Dawood G., Abrar N., Toossi Z., Minai A., Dojki M., et al. Selective increases in antibody isotypes and immunoglobulin G subclass responses to secreted antigens in tuberculosis patients and healthy household contacts of the patients. Clin Diagn Lab Immunol 1995, 2:726-732.
    • (1995) Clin Diagn Lab Immunol , vol.2 , pp. 726-732
    • Hussain, R.1    Dawood, G.2    Abrar, N.3    Toossi, Z.4    Minai, A.5    Dojki, M.6


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