T-cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus- like particles

Journal of Virology

Volumn 72, Issue 8, 1998, Pages 6665-6670

  Szomolanyi Tsuda, Eva ^a   Le, Quang P ^a   Garcea, Robert L ^b   Welsh, Raymond M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b Children's Hospital Colorado   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; VIRUS PROTEIN;

ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; GERMINAL CENTER; HELPER CELL; IMMUNE RESPONSE; IMMUNIZATION; POLYOMA VIRUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; VIRUS INFECTION;

EID: 0031949857     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.8.6665-6670.1998     Document Type: Article

References (27)

1. Bachmann, M. F., H. Hengartner, and R. M. Zinkernagel. 1995. T helper cell-independent neutralizing antibody responses against vesicular stomatitis virus: possible role of antigen patterns in B cell induction? Eur. J. Immunol. 25:3445-3451.
2. Bachmann, M. F., U. H. Rohrer, T. M. Kundig, K. Burki, H. Hengartner, and R. M. Zinkernagel. 1993. The influence of antigen organization on B cell responsiveness. Science 262:1448-1451.
3. Bachmann, M. F., and R. M. Zinkernagel. 1996. The influence of virus structure on antibody responses and virus scrotype formation. Immunol. Today 17:553-558.
4. Bachmann, M. F., and R. M. Zinkernagel. 1997. Neutralizing antiviral B cell responses. Annu. Rev. Immunol. 15:235-270.
5. Borrow, P., A. Tishon, S. Lee, J. Xu, I. S. Greval, M. B. A. Oldstone, and R. A. Flavell. 1996. CD40L-deficient mice show deficits in antiviral immunity and have impaired memory CD8+ CTL response. J. Exp. Med. 183:2129-2142.
6. Foy, T. M., J. D. Laman, A. Ledbetter, A. Aruffo, E. Claassen, and R. J. Noelle. 1994. gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. J. Exp. Med. 180:157-163.
7. Freer, G., C. Burkhart, I. Ciernik, M. F. Bachmann, H. Hengartner, and R. M. Zinkernagel. 1994. Vesicular stomatitis virus Indiana glycoprotein as a T-cell-dependent and -independent antigen. J. Virol. 68:3650-3655.
8. Garcea, R. L., and P. A. Estes. 1997. Purification of papovavirus virus-like particles (VLPs) from Sf9 insect cells, vol. 1. p. 521-527. In J. E. Celis (ed.), Cell biology: a laboratory handbook. Academic Press, San Diego, Calif.
9. Kelsoe, G. 1996. The germinal center: a crucible for lymphocyte selection. Semin. Immunol. 8:179-184.
10. Kosco-Vilbois, M. H., J.-Y. Bonnefoy, and Y. Chivatchko. 1997. The physiology of murine germinal center reactions. Immunol. Rev. 156:127-136.
11. Leavitt, A. D., T. M. Roberts, and R. L. Garcea. 1985. Polyomavirus major capsid protein VP1: purification after high level expression in Escherichia coli. J. Biol. Chem. 260:12803-12809.
12. MacLennan, I. C. M. 1994. Germinal centers. Annu. Rev. Immunol. 12:117-139.
13. Matsumoto, M., S. Mariathasan, M. H. Nahm, F. Baranyai, J. J. Peschon, and D. D. Chaplin. 1996. Affinity maturation without germinal centres in lymphotoxin-α-deficient mice. Nature 382:462-466.
14. Mizoguchi, A., E. Mizoguchi, C. Chiba, G. M. Spiekermann, S. Tonegawa, C. Nagler-Anderson, and A. K. Bhan. 1996. Cytokine imbalance and autoantibody production in T cell receptor a mutant mice with inflammatory bowel disease. J. Exp. Med. 183:847-856.
15. Mond, J. J., A. Lees, and C. M. Snapper. 1995. T cell-independent antigens type 2. Annu. Rev. Immunol. 13:655-692.
16. Montross, L., S. Watkins, R. B. Moreland, H. Mamon, D. L. Caspar, and R. L. Garcea. 1991. Nuclear assembly of polyomavirus capsids in insect cells expressing the major capsid protein VP1. J. Virol. 65:4991-4998.
17. Mosier, D. E., and B. Subbarao. 1982. Thymus-independent antigens: complexity of B cell activation revealed. Immunol. Today 3:217-227.
18. Rose, M. L., M. S. Birbeck, V. J. Wallis, J. A. Forester, and A. J. Davies. 1980. Peanut lectin binding properties of germinal centres of mouse lymphoid tissue. Nature 284:364-366.
19. Salunke, D. M., D. L. D. Caspar, and R. L. Garcea. 1986. Self-assembly of the purified polyomavirus capsid protein VP1. Cell 46:895-904.
20. Salunke, D. M., D. L. D. Caspar, and R. L. Garcea. 1989. Polymorphism in the assembly of polyomavirus capsid protein VP1. Biophys. J. 56:887-900.
21. Snapper, C. M., M. R. Kehry, B. E. Castle, and J. J. Mond. 1995. Multivalent, but not divalent, antigen receptor crosslinkers synergize with CD40L for induction of Ig synthesis and class switching in normal murine B cells. J. Immunol. 154:1177-1187.
22. Stehle, T., Y. Yan, T. L. Benjamin, and S. C. Harrison. 1994. Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment. Nature 369:160-163.
23. Szomolanyi-Tsuda, E., P. L. Dundon, I. Joris, L. D. Shultz, B. A. Woda, and R. M. Welsh. 1994. Acute, lethal, natural killer cell-resistant myeloproliferative disease induced by polyomavirus in severe combined immunodeficient mice. Am. J. Pathol. 144:359-371.
24. Szomolanyi-Tsuda, E., and R. M. Welsh. 1996. T cell-independent antibody-mediated clearance of polyomavirus in T cell-deficient mice. J. Exp. Med. 183:403-411.
25. Tsiagbe, V. K., G. Inghirami, and G. J. Thorbecke. 1996. The physiology of germinal centers. Crit. Rev. Immunol. 16:381-421.
26. Wen, L., S. J. Roberts, J. L. Viney, F. S. Wong, C. Mallick, R. C. Findly, Q. Peng, J. E. Craft, M. J. Owen, and A. C. Hayday. 1994. Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ+ cells. Nature 369:654-658.
27. Whitmire, J. K., M. K. Slifka, I. S. Grewal, R. A. Flavell, and R. Ahmed. 1996. CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection. J. Virol. 70:8375-8381.