-
1
-
-
73949119632
-
Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1
-
Benlahrech A, et al. 2009. Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1. Proc. Natl. Acad. Sci. U. S. A. 106:19940-19945.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 19940-19945
-
-
Benlahrech, A.1
-
2
-
-
56649105122
-
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the STEP study): a double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder SP, et al. 2008. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the STEP study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372:1881-1893.
-
(2008)
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
-
3
-
-
0037007670
-
HIV preferentially infects HIV-specific CD4+ T cells
-
Douek DC, et al. 2002. HIV preferentially infects HIV-specific CD4+ T cells. Nature 417:95-98.
-
(2002)
Nature
, vol.417
, pp. 95-98
-
-
Douek, D.C.1
-
4
-
-
79955551576
-
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
-
U.S.A.
-
Flynn BJ, et al. 2011. Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates. Proc. Natl. Acad. Sci. U. S. A. 108:7131-7136.
-
(2011)
Proc. Natl. Acad. Sci.
, vol.108
, pp. 7131-7136
-
-
Flynn, B.J.1
-
5
-
-
13944254982
-
Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
-
Flynn NM, et al. 2005. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J. Infect. Dis. 191: 654-665.
-
(2005)
J. Infect. Dis.
, vol.191
, pp. 654-665
-
-
Flynn, N.M.1
-
6
-
-
44649102135
-
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
-
U.S.A.
-
Keele BF, et al. 2008. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl. Acad. Sci. U. S. A. 105:7552-7557.
-
(2008)
Proc. Natl. Acad. Sci.
, vol.105
, pp. 7552-7557
-
-
Keele, B.F.1
-
7
-
-
77956799959
-
Mucosal trafficking of vector-specific CD4+ T lymphocytes following vaccination of rhesus monkeys with adenovirus serotype 5
-
Masek-Hammerman K, et al. 2010. Mucosal trafficking of vector-specific CD4+ T lymphocytes following vaccination of rhesus monkeys with adenovirus serotype 5. J. Virol. 84:9810-9816.
-
(2010)
J. Virol.
, vol.84
, pp. 9810-9816
-
-
Masek-hammerman, K.1
-
8
-
-
56649114351
-
HIV-1 vaccine-induced immunity in the testof-concept STEP study: a case-cohort analysis
-
McElrath MJ, et al. 2008. HIV-1 vaccine-induced immunity in the testof-concept STEP study: a case-cohort analysis. Lancet 372:1894-1905.
-
(2008)
Lancet
, vol.372
, pp. 1894-1905
-
-
Mcelrath, M.J.1
-
9
-
-
0031966533
-
Variation in virological parameters and antibody responses in macaques after atraumatic vaginal exposure to a pathogenic primary isolate of SIVmac251
-
Neildez O, et al. 1998. Variation in virological parameters and antibody responses in macaques after atraumatic vaginal exposure to a pathogenic primary isolate of SIVmac251. Res. Virol. 149:53-68.
-
(1998)
Res. Virol.
, vol.149
, pp. 53-68
-
-
Neildez, O.1
-
10
-
-
68349135329
-
Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans
-
O'Brien KL, et al. 2009. Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans. Nat. Med. 15:873-875.
-
(2009)
Nat. Med.
, vol.15
, pp. 873-875
-
-
O'brien, K.L.1
-
11
-
-
70349676021
-
Susceptibility to simian immunodeficiency virus ex vivo predicts outcome of a prime-boost vaccine after SIVmac239 challenge
-
Ochieng W, et al. 2009. Susceptibility to simian immunodeficiency virus ex vivo predicts outcome of a prime-boost vaccine after SIVmac239 challenge. J. Acquir. Immune Defic. Syndr. 52:162-169.
-
(2009)
J. Acquir. Immune Defic. Syndr.
, vol.52
, pp. 162-169
-
-
Ochieng, W.1
-
12
-
-
80555146755
-
+ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques
-
+ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques. J. Clin. Invest. 121: 4433-4445.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4433-4445
-
-
Ortiz, A.M.1
-
13
-
-
33845433434
-
Randomized, double-blind, placebocontrolled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
-
Pitisuttithum P, et al. 2006. Randomized, double-blind, placebocontrolled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J. Infect. Dis. 194:1661-1671.
-
(2006)
J. Infect. Dis.
, vol.194
, pp. 1661-1671
-
-
Pitisuttithum, P.1
-
14
-
-
84863116109
-
Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb STEP trial of a similar HIV-1 vaccine
-
Qureshi H, et al. 2012. Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb STEP trial of a similar HIV-1 vaccine. J. Virol. 86:2239-2250.
-
(2012)
J. Virol.
, vol.86
, pp. 2239-2250
-
-
Qureshi, H.1
-
15
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
Rerks-Ngarm S, et al. 2009. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361:2209-2220.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2209-2220
-
-
Rerks-ngarm, S.1
-
16
-
-
38549142426
-
Mhc class I haplotypes associated with survival time in simian immunodeficiency virus (SIV)-infected rhesus macaques
-
Sauermann U, et al. 2008. Mhc class I haplotypes associated with survival time in simian immunodeficiency virus (SIV)-infected rhesus macaques. Genes Immun. 9:69-80.
-
(2008)
Genes Immun.
, vol.9
, pp. 69-80
-
-
Sauermann, U.1
-
17
-
-
58149105397
-
Mucosal prior to systemic application of recombinant adenovirus boosting is more immunogenic than systemic application twice but confers similar protection against SIV-challenge in DNA vaccine-primed macaques
-
Schulte R, et al. 2009. Mucosal prior to systemic application of recombinant adenovirus boosting is more immunogenic than systemic application twice but confers similar protection against SIV-challenge in DNA vaccine-primed macaques. Virology 383:300-309.
-
(2009)
Virology
, vol.383
, pp. 300-309
-
-
Schulte, R.1
-
18
-
-
79953780057
-
Strong mucosal immune responses in SIV infected macaques contribute to viral control and preserved CD4+ T-cell levels in blood and mucosal tissues
-
Schultheiss T, Schulte R, Sauermann U, Ibing W, Stahl-Hennig C. 2011. Strong mucosal immune responses in SIV infected macaques contribute to viral control and preserved CD4+ T-cell levels in blood and mucosal tissues. Retrovirology 8:24.
-
(2011)
Retrovirology
, vol.8
, pp. 24
-
-
Schultheiss, T.1
Schulte, R.2
Sauermann, U.3
Ibing, W.4
Stahl-hennig, C.5
-
19
-
-
38749096240
-
The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J
-
Sekaly R-P. 2008. The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J. Exp. Med. 205:7-12.
-
(2008)
Exp. Med.
, vol.205
, pp. 7-12
-
-
Sekaly, R.-P.1
-
20
-
-
84857751302
-
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome
-
doi:10.1126/scitranslmed.3003165
-
Soghoian DZ, et al. 2012. HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci. Transl. Med 4:123ra25. doi:10.1126/scitranslmed.3003165.
-
(2012)
Sci. Transl. Med
, vol.4
-
-
Soghoian, D.Z.1
-
21
-
-
84868547474
-
Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques
-
doi:10.1371/journal.ppat.1000373
-
Stahl-Hennig C, et al. 2009. Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques. PLoS Pathog. 5:e1000373. doi:10.1371/journal.ppat.1000373.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Stahl-hennig, C.1
-
22
-
-
4444316121
-
Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein
-
U.S.A.
-
Staprans SI, et al. 2004. Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein. Proc. Natl. Acad. Sci. U. S. A. 101:13026-13031.
-
(2004)
Proc. Natl. Acad. Sci.
, vol.101
, pp. 13026-13031
-
-
Staprans, S.I.1
-
23
-
-
84862188248
-
Immunogenicity of DNA vaccines encoding dendritic cell targeted simian immunodeficiency virus antigen in rhesus macaques
-
doi:10.1371/journal.pone.0039038
-
Tenbusch M, et al. 2012. Immunogenicity of DNA vaccines encoding dendritic cell targeted simian immunodeficiency virus antigen in rhesus macaques. PLoS One 7:e39038. doi:10.1371/journal.pone.0039038.
-
(2012)
PLoS One
, vol.7
-
-
Tenbusch, M.1
-
24
-
-
50849126803
-
HIV vaccine development in the aftermath of the STEP study: re-focus on occult HIV infection?
-
doi:10.1371/journal.ppat.1000114
-
Überla K. 2008. HIV vaccine development in the aftermath of the STEP study: re-focus on occult HIV infection? PLoS Pathog. 4:e1000114. doi:10.1371/journal.ppat.1000114.
-
(2008)
PLoS Pathog
, vol.4
-
-
Überla, K.1
-
25
-
-
0033986873
-
+ T cells are rapidly eliminated in early SIV infection in vivo
-
+ T cells are rapidly eliminated in early SIV infection in vivo. J. Virol. 74:57-64.
-
(2000)
J. Virol.
, vol.74
, pp. 57-64
-
-
Veazey, R.S.1
-
26
-
-
0034694017
-
Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type
-
Wagner R, et al. 2000. Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type. Hum. Gene Ther. 11:2403-2413.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2403-2413
-
-
Wagner, R.1
|