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Volumn 17, Issue 7, 2013, Pages 694-706

Growing experience with mTOR inhibitors in pediatric solid organ transplantation

Author keywords

calcineurin inhibitors; children; pediatric; sirolimus; transplantation

Indexed keywords

BASILIXIMAB; CALCINEURIN INHIBITOR; CYCLOSPORIN; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; STEROID; TACROLIMUS;

EID: 84885431351     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/petr.12147     Document Type: Article
Times cited : (34)

References (86)
  • 1
    • 0034870203 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of sirolimus
    • Mahalati K, Kahan BD,. Clinical pharmacokinetics of sirolimus. Clin Pharmacokinet 2001: 40: 573-585.
    • (2001) Clin Pharmacokinet , vol.40 , pp. 573-585
    • Mahalati, K.1    Kahan, B.D.2
  • 4
    • 77952118055 scopus 로고    scopus 로고
    • R apamune ®. New York: Pfizer, Last updated.
    • R apamune ®. Summary of Product Characteristics. New York: Pfizer, Last updated 2011.
    • (2011) Summary of Product Characteristics
  • 5
    • 84885418465 scopus 로고    scopus 로고
    • C ertican ®. Basel, Switzerland: Novartis Pharma AG.
    • C ertican ®. Basic Prescribing Information. Basel, Switzerland: Novartis Pharma AG, 2012.
    • (2012) Basic Prescribing Information
  • 6
    • 0031008434 scopus 로고    scopus 로고
    • Pharmacokinetics of sirolimus in stable renal transplant patients after multiple oral dose administration
    • Zimmerman J, Kahan BD,. Pharmacokinetics of sirolimus in stable renal transplant patients after multiple oral dose administration. J Clin Pharmacol 1997: 37: 405-415.
    • (1997) J Clin Pharmacol , vol.37 , pp. 405-415
    • Zimmerman, J.1    Kahan, B.D.2
  • 7
    • 0036912410 scopus 로고    scopus 로고
    • Review of the proliferation inhibitor everolimus
    • Nashan B,. Review of the proliferation inhibitor everolimus. Expert Opin Investig Drugs 2002: 11: 1845-1857.
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 1845-1857
    • Nashan, B.1
  • 8
    • 0036138190 scopus 로고    scopus 로고
    • Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: A clinically relevant pharmacokinetic interaction
    • Kovarik JM, Kalbag J, Figueiredo J, Rouilly M, Frazier OL, Rordorf C,. Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: A clinically relevant pharmacokinetic interaction. J Clin Pharmacol 2002: 42: 95-99.
    • (2002) J Clin Pharmacol , vol.42 , pp. 95-99
    • Kovarik, J.M.1    Kalbag, J.2    Figueiredo, J.3    Rouilly, M.4    Frazier, O.L.5    Rordorf, C.6
  • 10
    • 38549132528 scopus 로고    scopus 로고
    • Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor
    • Brandhorst G, Tenderich G, Zittermann A, et al. Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor. Ther Drug Monit 2008: 30: 113-116.
    • (2008) Ther Drug Monit , vol.30 , pp. 113-116
    • Brandhorst, G.1    Tenderich, G.2    Zittermann, A.3
  • 11
    • 10744220677 scopus 로고    scopus 로고
    • A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (Neoral) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year
    • Ciancio G, Burke GW, Gaynor JJ, et al. A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (Neoral) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year. Transplantation 2004: 77: 244-251.
    • (2004) Transplantation , vol.77 , pp. 244-251
    • Ciancio, G.1    Burke, G.W.2    Gaynor, J.J.3
  • 12
    • 18044379147 scopus 로고    scopus 로고
    • Effects of calcineurin inhibitors on sirolimus pharmacokinetics during staggered administration in renal transplant recipients
    • Wu FL, Tsai MK, Chen RR, et al. Effects of calcineurin inhibitors on sirolimus pharmacokinetics during staggered administration in renal transplant recipients. Pharmacotherapy 2005: 25: 646-653.
    • (2005) Pharmacotherapy , vol.25 , pp. 646-653
    • Wu, F.L.1    Tsai, M.K.2    Chen, R.R.3
  • 13
    • 84876695987 scopus 로고    scopus 로고
    • De novo therapy with everolimus and reduced-exposure cyclosporine following pediatric kidney transplantation: A prospective, multicenter, 12-month study
    • for the Everolimus Pediatric Study Group.
    • Grushkin C, Mahan JD, Mange KC, Hexham JM, Ettenger R, for the Everolimus Pediatric Study Group. De novo therapy with everolimus and reduced-exposure cyclosporine following pediatric kidney transplantation: A prospective, multicenter, 12-month study. Pediatr Transplant 2013: 17: 237-243.
    • (2013) Pediatr Transplant , vol.17 , pp. 237-243
    • Grushkin, C.1    Mahan, J.D.2    Mange, K.C.3    Hexham, J.M.4    Ettenger, R.5
  • 14
    • 77957205634 scopus 로고    scopus 로고
    • De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation
    • Pape L, Offner G, Kreuzer M, et al. De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation. Am J Transplant 2010: 10: 2349-2354.
    • (2010) Am J Transplant , vol.10 , pp. 2349-2354
    • Pape, L.1    Offner, G.2    Kreuzer, M.3
  • 15
    • 80052648009 scopus 로고    scopus 로고
    • Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data
    • Pape L, Lehner F, Blume C, Ahlenstiel T,. Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data. Transplantation 2011: 92: 658-662.
    • (2011) Transplantation , vol.92 , pp. 658-662
    • Pape, L.1    Lehner, F.2    Blume, C.3    Ahlenstiel, T.4
  • 16
    • 72549098580 scopus 로고    scopus 로고
    • A randomized double-blind, placebo controlled trial of steroid withdrawal after pediatric renal transplantation
    • Benfield MR, Bartosh S, Ikle D, et al. A randomized double-blind, placebo controlled trial of steroid withdrawal after pediatric renal transplantation. Am J Transplant 2010: 10: 81-88.
    • (2010) Am J Transplant , vol.10 , pp. 81-88
    • Benfield, M.R.1    Bartosh, S.2    Ikle, D.3
  • 17
    • 42149091128 scopus 로고    scopus 로고
    • Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids
    • Macdonald RA, Smith JM, Ho M, et al. Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids. Am J Transplant 2008: 8: 984-989.
    • (2008) Am J Transplant , vol.8 , pp. 984-989
    • Macdonald, R.A.1    Smith, J.M.2    Ho, M.3
  • 18
    • 78649843933 scopus 로고    scopus 로고
    • Protocol biopsy-driven interventions after pediatric renal transplantation
    • Kanzelmeyer NK, Ahlenstiel T, Drube J, et al. Protocol biopsy-driven interventions after pediatric renal transplantation. Pediatr Transplant 2010: 14: 1012-1018.
    • (2010) Pediatr Transplant , vol.14 , pp. 1012-1018
    • Kanzelmeyer, N.K.1    Ahlenstiel, T.2    Drube, J.3
  • 19
    • 43249103406 scopus 로고    scopus 로고
    • Multicenter trial of everolimus in pediatric renal transplant recipients: Results at three year
    • Ettenger R, Hoyer PF, Grimm P, et al. Multicenter trial of everolimus in pediatric renal transplant recipients: Results at three year. Pediatr Transplant 2008: 12: 456-463.
    • (2008) Pediatr Transplant , vol.12 , pp. 456-463
    • Ettenger, R.1    Hoyer, P.F.2    Grimm, P.3
  • 20
    • 33646915970 scopus 로고    scopus 로고
    • Safety and efficacy of a calcineurin inhibitor avoidance regimen in pediatric renal transplantation
    • Harmon W, Meyers K, Inglefinger J, et al. Safety and efficacy of a calcineurin inhibitor avoidance regimen in pediatric renal transplantation. J Am Soc Nephrol 2006: 17: 1735-1745.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1735-1745
    • Harmon, W.1    Meyers, K.2    Inglefinger, J.3
  • 21
    • 78349251703 scopus 로고    scopus 로고
    • Histological progression of chronic renal allograft injury comparing sirolimus and mycophenolate mofetil-based protocols. A single-center, prospective, randomized, controlled study
    • Blydt-Hansen TD, Gibson IW, Birk PE,. Histological progression of chronic renal allograft injury comparing sirolimus and mycophenolate mofetil-based protocols. A single-center, prospective, randomized, controlled study. Pediatr Transplant 2010: 14: 909-918.
    • (2010) Pediatr Transplant , vol.14 , pp. 909-918
    • Blydt-Hansen, T.D.1    Gibson, I.W.2    Birk, P.E.3
  • 22
    • 33745713208 scopus 로고    scopus 로고
    • SRL-based immunosuppression vs. CNI minimization in pediatric renal transplant recipients with chronic CNI nephrotoxicity
    • Höcker B, Feneberg R, Köpf S, et al. SRL-based immunosuppression vs. CNI minimization in pediatric renal transplant recipients with chronic CNI nephrotoxicity. Pediatr Transplant 2006: 10: 593-601.
    • (2006) Pediatr Transplant , vol.10 , pp. 593-601
    • Höcker, B.1    Feneberg, R.2    Köpf, S.3
  • 23
    • 34147144078 scopus 로고    scopus 로고
    • Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A
    • Pape L, Ahlenstiel T, Ehrich JH, Offner G,. Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A. Pediatr Transplant 2007: 11: 291-295.
    • (2007) Pediatr Transplant , vol.11 , pp. 291-295
    • Pape, L.1    Ahlenstiel, T.2    Ehrich, J.H.3    Offner, G.4
  • 24
    • 22844442933 scopus 로고    scopus 로고
    • Adding sirolimus to tacrolimus-based immunosuppression in pediatric renal transplant recipients reduces tacrolimus exposure
    • Filler G, Womiloju T, Feber J, Lepage N, Christians U,. Adding sirolimus to tacrolimus-based immunosuppression in pediatric renal transplant recipients reduces tacrolimus exposure. Am J Transplant 2005: 5: 2005-2010.
    • (2005) Am J Transplant , vol.5 , pp. 2005-2010
    • Filler, G.1    Womiloju, T.2    Feber, J.3    Lepage, N.4    Christians, U.5
  • 25
    • 74349124122 scopus 로고    scopus 로고
    • Steroid avoidance using sirolimus and cyclosporine in pediatric renal transplantation: One year analysis
    • Iorember FM, Patel HP, Ohana A, et al. Steroid avoidance using sirolimus and cyclosporine in pediatric renal transplantation: One year analysis. Pediatr Transplant 2010: 14: 93-99.
    • (2010) Pediatr Transplant , vol.14 , pp. 93-99
    • Iorember, F.M.1    Patel, H.P.2    Ohana, A.3
  • 27
    • 53849114660 scopus 로고    scopus 로고
    • Tacrolimus withdrawal and conversion to sirolimus at three months post-pediatric renal transplantation
    • Hymes LC, Warshaw BL, Amaral SG, Greenbaum LA,. Tacrolimus withdrawal and conversion to sirolimus at three months post-pediatric renal transplantation. Pediatr Transplant 2008: 12: 773-777.
    • (2008) Pediatr Transplant , vol.12 , pp. 773-777
    • Hymes, L.C.1    Warshaw, B.L.2    Amaral, S.G.3    Greenbaum, L.A.4
  • 29
    • 67249140650 scopus 로고    scopus 로고
    • Long-term follow-up of 100 high-risk renal transplant recipients converted from calcineurin inhibitors to sirolimus: A single center experience
    • Halim MA, Al-Otaibi T, Johny KV, et al. Long-term follow-up of 100 high-risk renal transplant recipients converted from calcineurin inhibitors to sirolimus: A single center experience. Transplant Proc 2009: 41: 1666-1670.
    • (2009) Transplant Proc , vol.41 , pp. 1666-1670
    • Halim, M.A.1    Al-Otaibi, T.2    Johny, K.V.3
  • 30
    • 34548302081 scopus 로고    scopus 로고
    • Early experience with conversion to sirolimus in a pediatric renal transplant population
    • Powell HR, Kara T, Jones CL,. Early experience with conversion to sirolimus in a pediatric renal transplant population. Pediatr Nephrol 2007: 22: 1773-1777.
    • (2007) Pediatr Nephrol , vol.22 , pp. 1773-1777
    • Powell, H.R.1    Kara, T.2    Jones, C.L.3
  • 31
    • 33746924485 scopus 로고    scopus 로고
    • Conversion to sirolimus in pediatric renal transplantation recipients
    • Garcia CD, Bittencourt VB, Alves AB, et al. Conversion to sirolimus in pediatric renal transplantation recipients. Transplant Proc 2006: 38: 1901-1903.
    • (2006) Transplant Proc , vol.38 , pp. 1901-1903
    • Garcia, C.D.1    Bittencourt, V.B.2    Alves, A.B.3
  • 33
    • 33745713210 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy
    • Falger JC, Mueller T, Arbeiter K, et al. Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy. Pediatr Transplant 2006: 10: 474-478.
    • (2006) Pediatr Transplant , vol.10 , pp. 474-478
    • Falger, J.C.1    Mueller, T.2    Arbeiter, K.3
  • 34
    • 55949095133 scopus 로고    scopus 로고
    • Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation
    • Weintraub L, Li L, Kambham N, et al. Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation. Pediatr Transplant 2008: 12: 541-549.
    • (2008) Pediatr Transplant , vol.12 , pp. 541-549
    • Weintraub, L.1    Li, L.2    Kambham, N.3
  • 35
    • 80055016105 scopus 로고    scopus 로고
    • Sirolimus as renal and immunological rescue agent in pediatric liver transplant recipients
    • Basso MS, Subramaniam P, Tredger M, et al. Sirolimus as renal and immunological rescue agent in pediatric liver transplant recipients. Pediatr Transplant 2011: 15: 722-727.
    • (2011) Pediatr Transplant , vol.15 , pp. 722-727
    • Basso, M.S.1    Subramaniam, P.2    Tredger, M.3
  • 37
    • 84885420617 scopus 로고    scopus 로고
    • Pediatric liver transplantation: Single centre experience with CNI-free immunosuppression
    • Sturm E, Handgretinger R, Königsrainer A, Nadalin S,. Pediatric liver transplantation: Single centre experience with CNI-free immunosuppression. Transpl Int 2011: 24 (Suppl 3): 20.
    • (2011) Transpl Int , vol.24 , Issue.SUPPL. 3 , pp. 20
    • Sturm, E.1    Handgretinger, R.2    Königsrainer, A.3    Nadalin, S.4
  • 38
    • 64649097287 scopus 로고    scopus 로고
    • Sirolimus in pediatric liver transplantation: A single-center experience
    • Gibelli NE, Tannuri U, Pinho-Apezzato ML, et al. Sirolimus in pediatric liver transplantation: A single-center experience. Transplant Proc 2009: 41: 901-903.
    • (2009) Transplant Proc , vol.41 , pp. 901-903
    • Gibelli, N.E.1    Tannuri, U.2    Pinho-Apezzato, M.L.3
  • 39
    • 4043089144 scopus 로고    scopus 로고
    • Improvement in renal function and rejection control in pediatric liver transplant recipients with the introduction of sirolimus
    • Casas-Melley AT, Falkenstein KP, Flynn LM, Ziegler VL, Dunn SP,. Improvement in renal function and rejection control in pediatric liver transplant recipients with the introduction of sirolimus. Pediatr Transplant 2004: 8: 362-366.
    • (2004) Pediatr Transplant , vol.8 , pp. 362-366
    • Casas-Melley, A.T.1    Falkenstein, K.P.2    Flynn, L.M.3    Ziegler, V.L.4    Dunn, S.P.5
  • 40
    • 2942726283 scopus 로고    scopus 로고
    • Sirolimus for pediatric liver transplant recipients with post-transplant lymphoproliferative disease and hepatoblastoma
    • Jimenez-Rivera C, Avitzur Y, Fecteau AH, Jones N, Grant D, Ng VL,. Sirolimus for pediatric liver transplant recipients with post-transplant lymphoproliferative disease and hepatoblastoma. Pediatr Transplant 2004: 8: 243-248.
    • (2004) Pediatr Transplant , vol.8 , pp. 243-248
    • Jimenez-Rivera, C.1    Avitzur, Y.2    Fecteau, A.H.3    Jones, N.4    Grant, D.5    Ng, V.L.6
  • 42
    • 84885431544 scopus 로고    scopus 로고
    • Everolimus in pediatric heart transplantation: Report on efficacy, pharmacokinetics and safety in infants below the age of 1 year
    • :.
    • Lehmkuhl HB, Schubert S, Dandel M, et al. Everolimus in pediatric heart transplantation: Report on efficacy, pharmacokinetics and safety in infants below the age of 1 year. J Heart Lung Transplant 2009: 28 (2 Suppl): S234.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.2 SUPPL.
    • Lehmkuhl, H.B.1    Schubert, S.2    Dandel, M.3
  • 43
    • 80055003426 scopus 로고    scopus 로고
    • Calcineurin inhibitor minimization using sirolimus leads to improved renal function in pediatric heart transplant recipients
    • Chinnock TJ, Shankel T, Deming D, et al. Calcineurin inhibitor minimization using sirolimus leads to improved renal function in pediatric heart transplant recipients. Pediatr Transplant 2011: 15: 746-749.
    • (2011) Pediatr Transplant , vol.15 , pp. 746-749
    • Chinnock, T.J.1    Shankel, T.2    Deming, D.3
  • 44
    • 84885421713 scopus 로고    scopus 로고
    • Efficacy and safety of immunosuppression with everolimus in pediatric heart transplantation
    • :.
    • Schweiger M, Dandel M, Hiemann N, et al. Efficacy and safety of immunosuppression with everolimus in pediatric heart transplantation. Eur Surg 2011: 43 (Suppl): 16.
    • (2011) Eur Surg , vol.43 , Issue.SUPPL. , pp. 16
    • Schweiger, M.1    Dandel, M.2    Hiemann, N.3
  • 45
    • 84885430977 scopus 로고    scopus 로고
    • Everolimus in pediatric heart transplantation: A Spanish center experience
    • :.
    • Vazquez-Alvarez MC, Camino-Lopez M, Medrano-Lopez C, et al. Everolimus in pediatric heart transplantation: A Spanish center experience. J Heart Lung Transplant 2011: 30 (4 Suppl S): S221.
    • (2011) J Heart Lung Transplant , vol.30 , Issue.4 SUPPL. S
    • Vazquez-Alvarez, M.C.1    Camino-Lopez, M.2    Medrano-Lopez, C.3
  • 46
    • 82155196444 scopus 로고    scopus 로고
    • Renal function in children with heart transplantation after switching to CNI-free immunosuppression with everolimus
    • Behnke-Hall K, Bauer J, Thul J, et al. Renal function in children with heart transplantation after switching to CNI-free immunosuppression with everolimus. Pediatr Transplant 2011: 15: 784-789.
    • (2011) Pediatr Transplant , vol.15 , pp. 784-789
    • Behnke-Hall, K.1    Bauer, J.2    Thul, J.3
  • 47
    • 82155177557 scopus 로고    scopus 로고
    • Comparison of de novo everolimus, AZA and MMF in cyclosporine based immunosuppressive protocol in pediatric heart transplant patients
    • Schubert S, Lehmkuhl HB, Huebler M, Hetzer R, Berger F,. Comparison of de novo everolimus, AZA and MMF in cyclosporine based immunosuppressive protocol in pediatric heart transplant patients. J Heart Lung Transplant 2010: 29 (2 Suppl S): S107.
    • (2010) J Heart Lung Transplant , vol.29 , Issue.2 SUPPL. S
    • Schubert, S.1    Lehmkuhl, H.B.2    Huebler, M.3    Hetzer, R.4    Berger, F.5
  • 48
    • 77950676475 scopus 로고    scopus 로고
    • Indications, tolerance and complications of a sirolimus and calcineurin inhibitor immunosuppression regimen: Intermediate experience in pediatric heart transplantation recipients
    • Matthews K, Gossett J, Kappelle PV, Jellen G, Pahl E,. Indications, tolerance and complications of a sirolimus and calcineurin inhibitor immunosuppression regimen: Intermediate experience in pediatric heart transplantation recipients. Pediatr Transplant 2010: 14: 402-408.
    • (2010) Pediatr Transplant , vol.14 , pp. 402-408
    • Matthews, K.1    Gossett, J.2    Kappelle, P.V.3    Jellen, G.4    Pahl, E.5
  • 49
    • 84885422220 scopus 로고    scopus 로고
    • Use of everolimus in pediatric patients after heart transplantation: A single center experience
    • Carducci FIC, Grutter G, D'argenio P, Parisi F,. Use of everolimus in pediatric patients after heart transplantation: A single center experience. J Heart Lung Transplant 2009: 28 (2 Suppl): S234.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.2 SUPPL.
    • Carducci, F.I.C.1    Grutter, G.2    D'Argenio, P.3    Parisi, F.4
  • 50
    • 33646138493 scopus 로고    scopus 로고
    • Early renal benefit of rapamycin combined with reduced calcineurin inhibitor dose in pediatric heart transplantation patients
    • Balfour IC, Srun SW, Wood EG, Belsha CW, Marshall DL, Ferdman BR,. Early renal benefit of rapamycin combined with reduced calcineurin inhibitor dose in pediatric heart transplantation patients. J Heart Lung Transplant 2006: 25: 518-522.
    • (2006) J Heart Lung Transplant , vol.25 , pp. 518-522
    • Balfour, I.C.1    Srun, S.W.2    Wood, E.G.3    Belsha, C.W.4    Marshall, D.L.5    Ferdman, B.R.6
  • 51
    • 13444273352 scopus 로고    scopus 로고
    • Sirolimus immunosuppression in pediatric heart transplant recipients: A single-center experience
    • Lobach NE, Pollock-Barziv SM, West LJ, Dipchand AI,. Sirolimus immunosuppression in pediatric heart transplant recipients: A single-center experience. J Heart Lung Transplant 2005: 24: 184-189.
    • (2005) J Heart Lung Transplant , vol.24 , pp. 184-189
    • Lobach, N.E.1    Pollock-Barziv, S.M.2    West, L.J.3    Dipchand, A.I.4
  • 52
    • 79953874227 scopus 로고    scopus 로고
    • High prevalence of renal dysfunction in children after liver transplantation: Non-invasive diagnosis using a cystatin C-based equation
    • Brinkert F, Kemper MJ, Briem-Richter A, Van Husen M, Treszl A, Ganschow R,. High prevalence of renal dysfunction in children after liver transplantation: Non-invasive diagnosis using a cystatin C-based equation. Nephrol Dial Transplant 2011: 26: 1407-1412.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 1407-1412
    • Brinkert, F.1    Kemper, M.J.2    Briem-Richter, A.3    Van Husen, M.4    Treszl, A.5    Ganschow, R.6
  • 53
    • 33646516183 scopus 로고    scopus 로고
    • High prevalence of renal dysfunction in long-term survivors after pediatric liver transplantation
    • Campbell KM, Yazigi N, Ryckman FC, et al. High prevalence of renal dysfunction in long-term survivors after pediatric liver transplantation. J Pediatr 2006: 148: 475-480.
    • (2006) J Pediatr , vol.148 , pp. 475-480
    • Campbell, K.M.1    Yazigi, N.2    Ryckman, F.C.3
  • 54
    • 84870542050 scopus 로고    scopus 로고
    • Risk factors for end-stage kidney disease after pediatric liver transplantation
    • Ruebner RL, Reese P, Denburg MR, et al. Risk factors for end-stage kidney disease after pediatric liver transplantation. Am J Transplant 2012: 12: 3398-3405.
    • (2012) Am J Transplant , vol.12 , pp. 3398-3405
    • Ruebner, R.L.1    Reese, P.2    Denburg, M.R.3
  • 55
    • 55949105486 scopus 로고    scopus 로고
    • Renal function in pediatric liver transplantation: A long-term follow-up study
    • Harambat J, Ranchin B, Dubourg L, et al. Renal function in pediatric liver transplantation: A long-term follow-up study. Transplantation 2008: 86: 1028-1034.
    • (2008) Transplantation , vol.86 , pp. 1028-1034
    • Harambat, J.1    Ranchin, B.2    Dubourg, L.3
  • 56
    • 59649126728 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial
    • Sirolimus Convert Trial Study Group.
    • Schena FP, Pascoe MD, Alberu J, et al. Sirolimus Convert Trial Study Group. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation 2009: 87: 233-242.
    • (2009) Transplantation , vol.87 , pp. 233-242
    • Schena, F.P.1    Pascoe, M.D.2    Alberu, J.3
  • 57
    • 74949094555 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for the care of kidney transplant recipients
    • KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Transplant 2009: 9: S1-S155.
    • (2009) Am J Transplant , vol.9
  • 58
    • 53149101690 scopus 로고    scopus 로고
    • Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus
    • Wang SS, Chou NK, Chi NH, et al. Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus. Transplant Proc 2008: 40: 2607-2608.
    • (2008) Transplant Proc , vol.40 , pp. 2607-2608
    • Wang, S.S.1    Chou, N.K.2    Chi, N.H.3
  • 59
    • 77956225968 scopus 로고    scopus 로고
    • Post-renal transplant surgical complications with newer immunosuppressive drugs: Mycophenolate mofetil vs m-TOR inhibitors
    • Srivastava A, Muruganandham K, Vinodh PB, et al. Post-renal transplant surgical complications with newer immunosuppressive drugs: Mycophenolate mofetil vs. m-TOR inhibitors. Int Urol Nephrol 2010: 42: 279-284.
    • (2010) Int Urol Nephrol , vol.42 , pp. 279-284
    • Srivastava, A.1    Muruganandham, K.2    Vinodh, P.B.3
  • 60
    • 80052078140 scopus 로고    scopus 로고
    • Linear growth in pediatric renal transplant recipients receiving sirolimus
    • Hymes LC, Warshaw BL,. Linear growth in pediatric renal transplant recipients receiving sirolimus. Pediatr Transplant 2011: 15: 570-572.
    • (2011) Pediatr Transplant , vol.15 , pp. 570-572
    • Hymes, L.C.1    Warshaw, B.L.2
  • 61
    • 67650938542 scopus 로고    scopus 로고
    • Calcineurin inhibitor minimization in the Symphony study: Observational results 3 years after transplantation
    • Ekberg H, Bernasconi C, Tedesco-Silva H, et al. Calcineurin inhibitor minimization in the Symphony study: Observational results 3 years after transplantation. Am J Transplant 2009: 9: 1876-1885.
    • (2009) Am J Transplant , vol.9 , pp. 1876-1885
    • Ekberg, H.1    Bernasconi, C.2    Tedesco-Silva, H.3
  • 62
    • 84857194014 scopus 로고    scopus 로고
    • Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: Pooled analysis of three clinical trials
    • Brennan DC, Legendre C, Patel D, et al. Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: Pooled analysis of three clinical trials. Am J Transplant 2011: 11: 2453-2462.
    • (2011) Am J Transplant , vol.11 , pp. 2453-2462
    • Brennan, D.C.1    Legendre, C.2    Patel, D.3
  • 64
    • 84862528335 scopus 로고    scopus 로고
    • Targeting mTOR pathways in human malignancies
    • Fasolo A, Sessa C,. Targeting mTOR pathways in human malignancies. Curr Pharm Des 2012: 18: 2766-2777.
    • (2012) Curr Pharm des , vol.18 , pp. 2766-2777
    • Fasolo, A.1    Sessa, C.2
  • 66
    • 70149093417 scopus 로고    scopus 로고
    • Growth failure associated with sirolimus: Case report
    • Rangel GA, Ariceta G,. Growth failure associated with sirolimus: Case report. Pediatr Nephrol 2009: 24: 2047-2050.
    • (2009) Pediatr Nephrol , vol.24 , pp. 2047-2050
    • Rangel, G.A.1    Ariceta, G.2
  • 67
    • 79959963307 scopus 로고    scopus 로고
    • Growth of kidney-transplanted pediatric patients treated with sirolimus
    • Gonzalez D, Garcia CD, Azocar M, et al. Growth of kidney-transplanted pediatric patients treated with sirolimus. Pediatr Nephrol 2011: 26: 961-966.
    • (2011) Pediatr Nephrol , vol.26 , pp. 961-966
    • Gonzalez, D.1    Garcia, C.D.2    Azocar, M.3
  • 68
    • 84882452607 scopus 로고    scopus 로고
    • Longitudinal growth on an everolimus- versus an MMF-based steroid-free immunosuppressive regimen in paediatric renal transplant recipients
    • Billing H, Burmeister G, Plotnizki L, et al. Longitudinal growth on an everolimus- versus an MMF-based steroid-free immunosuppressive regimen in paediatric renal transplant recipients. Transpl Int 2013: 26: 903-909.
    • (2013) Transpl Int , vol.26 , pp. 903-909
    • Billing, H.1    Burmeister, G.2    Plotnizki, L.3
  • 69
    • 84885431318 scopus 로고    scopus 로고
    • MTOR and CNI without steroids in the maintenance of kidney transplanted children
    • :.
    • Vilalta R, Lara E, Alvaro M, et al. MTOR and CNI without steroids in the maintenance of kidney transplanted children. Pediatr Transplant 2011: 15 (Suppl 1): 410.
    • (2011) Pediatr Transplant , vol.15 , Issue.SUPPL. 1 , pp. 410
    • Vilalta, R.1    Lara, E.2    Alvaro, M.3
  • 70
    • 84859702650 scopus 로고    scopus 로고
    • The impact of sirolimus on sex hormones in male adolescent kidney recipients
    • Cavanaugh TM, Schoenemen H, Goebel J,. The impact of sirolimus on sex hormones in male adolescent kidney recipients. Pediatr Transplant 2012: 16: 280-285.
    • (2012) Pediatr Transplant , vol.16 , pp. 280-285
    • Cavanaugh, T.M.1    Schoenemen, H.2    Goebel, J.3
  • 71
    • 20344400146 scopus 로고    scopus 로고
    • Gonadal function and immunosuppressive therapy after renal transplantation
    • Tondolo V, Citterio F, Panocchia N, et al. Gonadal function and immunosuppressive therapy after renal transplantation. Transplant Proc 2005: 37: 1915-1917.
    • (2005) Transplant Proc , vol.37 , pp. 1915-1917
    • Tondolo, V.1    Citterio, F.2    Panocchia, N.3
  • 73
    • 3042698635 scopus 로고    scopus 로고
    • Sirolimus impairs gonadal function in heart transplant recipients
    • Kaczmarek I, Groetzner J, Adamidis I, et al. Sirolimus impairs gonadal function in heart transplant recipients. Am J Transplant 2004: 4: 1084-1088.
    • (2004) Am J Transplant , vol.4 , pp. 1084-1088
    • Kaczmarek, I.1    Groetzner, J.2    Adamidis, I.3
  • 74
    • 84866731714 scopus 로고    scopus 로고
    • Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: A critical review of the literature
    • Nashan B, Citterio F,. Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: A critical review of the literature. Transplantation 2012: 94: 547-561.
    • (2012) Transplantation , vol.94 , pp. 547-561
    • Nashan, B.1    Citterio, F.2
  • 75
    • 77957583305 scopus 로고    scopus 로고
    • Efficacy and safety of de novo or early everolimus with low cyclosporine in deceased-donor kidney transplant recipients at specified risk of delayed graft function: 12-month results of a randomized, multicenter trial
    • Dantal J, Berthoux F, Moal M-C, et al. Efficacy and safety of de novo or early everolimus with low cyclosporine in deceased-donor kidney transplant recipients at specified risk of delayed graft function: 12-month results of a randomized, multicenter trial. Transpl Int 2010: 23: 1084-1093.
    • (2010) Transpl Int , vol.23 , pp. 1084-1093
    • Dantal, J.1    Berthoux, F.2    Moal, M.-C.3
  • 76
    • 33750433893 scopus 로고    scopus 로고
    • Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis
    • Neef M, Ledermann M, Saegesser H, Schneider V, Reichen J,. Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis. J Hepatol 2006: 45: 786-796.
    • (2006) J Hepatol , vol.45 , pp. 786-796
    • Neef, M.1    Ledermann, M.2    Saegesser, H.3    Schneider, V.4    Reichen, J.5
  • 77
    • 0032738763 scopus 로고    scopus 로고
    • Rapamycin inhibits stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis
    • Zhu J, Wu J, Frizell E, et al. Rapamycin inhibits stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. Gastroenterology 1999: 117: 1198-1204.
    • (1999) Gastroenterology , vol.117 , pp. 1198-1204
    • Zhu, J.1    Wu, J.2    Frizell, E.3
  • 78
    • 79960440859 scopus 로고    scopus 로고
    • Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis
    • Patsenker E, Schneider V, Ledermann M, et al. Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis. J Hepatol 2011: 55: 388-398.
    • (2011) J Hepatol , vol.55 , pp. 388-398
    • Patsenker, E.1    Schneider, V.2    Ledermann, M.3
  • 79
    • 79952265424 scopus 로고    scopus 로고
    • The impact of sirolimus on hepatitis C recurrence after liver transplantation
    • Asthana S, Toso C, Meeberg G, et al. The impact of sirolimus on hepatitis C recurrence after liver transplantation. Can J Gastroenterol 2011: 25: 28-34.
    • (2011) Can J Gastroenterol , vol.25 , pp. 28-34
    • Asthana, S.1    Toso, C.2    Meeberg, G.3
  • 80
    • 83555164165 scopus 로고    scopus 로고
    • Limiting hepatitis C virus progression in liver transplant recipients using sirolimus-based immunosuppression
    • McKenna GJ, Trotter JF, Klintmalm E, et al. Limiting hepatitis C virus progression in liver transplant recipients using sirolimus-based immunosuppression. Am J Transplant 2011: 11: 2379-2387.
    • (2011) Am J Transplant , vol.11 , pp. 2379-2387
    • McKenna, G.J.1    Trotter, J.F.2    Klintmalm, E.3
  • 81
    • 0034810020 scopus 로고    scopus 로고
    • Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients
    • Ettenger RB, Grimm EM,. Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients. Am J Kidney Dis 2001: 38 (Suppl 2): S22-S28.
    • (2001) Am J Kidney Dis , vol.38 , Issue.SUPPL. 2
    • Ettenger, R.B.1    Grimm, E.M.2
  • 82
    • 10744220571 scopus 로고    scopus 로고
    • Everolimus in pediatric de novo renal transplant patients
    • Hoyer PF, Ettenger R, Kovarik JM, et al. Everolimus in pediatric de novo renal transplant patients. Transplantation 2003: 75: 2082-2085.
    • (2003) Transplantation , vol.75 , pp. 2082-2085
    • Hoyer, P.F.1    Ettenger, R.2    Kovarik, J.M.3
  • 83
    • 1942487280 scopus 로고    scopus 로고
    • Short sirolimus half-life in pediatric renal transplant recipients on a calcineurin inhibitor-free protocol
    • Schachter AD, Meyers KE, Spaneas LD, et al. Short sirolimus half-life in pediatric renal transplant recipients on a calcineurin inhibitor-free protocol. Pediatr Transplant 2004: 8: 171-177.
    • (2004) Pediatr Transplant , vol.8 , pp. 171-177
    • Schachter, A.D.1    Meyers, K.E.2    Spaneas, L.D.3
  • 84
    • 78650313824 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free immunosuppression in pediatric renal transplantation: A viable option?
    • Höcker B, Tönshoff B,. Calcineurin inhibitor-free immunosuppression in pediatric renal transplantation: A viable option? Paediatr Drugs 2011: 13: 49-69.
    • (2011) Paediatr Drugs , vol.13 , pp. 49-69
    • Höcker, B.1    Tönshoff, B.2
  • 85
    • 20544461856 scopus 로고    scopus 로고
    • Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin)
    • Reyes J, Mazariegos GV, Abu-Elmagd K, et al. Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin). Am J Transplant 2005: 5: 1430-1436.
    • (2005) Am J Transplant , vol.5 , pp. 1430-1436
    • Reyes, J.1    Mazariegos, G.V.2    Abu-Elmagd, K.3
  • 86
    • 0035884399 scopus 로고    scopus 로고
    • Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus
    • Sindhi R, Webber S, Venkataramanan R, et al. Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus. Transplantation 2001: 72: 851-855.
    • (2001) Transplantation , vol.72 , pp. 851-855
    • Sindhi, R.1    Webber, S.2    Venkataramanan, R.3


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