Growth failure associated with sirolimus: Case report

Pediatric Nephrology

Volumn 24, Issue 10, 2009, Pages 2047-2050

  Rangel, Gloria A ^a   Ariceta, Gema ^a  

^a HOSPITAL DE CRUCES   (Spain)

Author keywords

Child; Growth failure; Kidney transplant; Sirolimus

Indexed keywords

ATORVASTATIN; CALCINEURIN INHIBITOR; CYCLOSPORIN A; DACLIZUMAB; LISINOPRIL; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; RECOMBINANT GROWTH HORMONE;

ACUTE KIDNEY FAILURE; ARTICLE; BODY HEIGHT; CASE REPORT; CATCH UP GROWTH; CHILD; CHRONIC KIDNEY DISEASE; CREATININE CLEARANCE; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; GROWTH DISORDER; GROWTH RATE; GROWTH RETARDATION; HEMOLYTIC ANEMIA; HEMOLYTIC UREMIC SYNDROME; HUMAN; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LABORATORY DIAGNOSIS; NEPHROTIC SYNDROME; PERITONEAL DIALYSIS; PRIORITY JOURNAL; PROTEINURIA; SCHOOL CHILD; SCLEROSIS; THROMBOCYTOPENIA; UPPER RESPIRATORY TRACT INFECTION;

BODY HEIGHT; CHILD; CYCLOSPORINE; FEMALE; GRAFT REJECTION; HUMAN GROWTH HORMONE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; SIROLIMUS;

EID: 70149093417     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-009-1215-9     Document Type: Article

References (17)

1. Dharnidharka VR (2005) Sirolimus in pediatric solid organ transplantation. Pediatr Transplant 9:427-429
2. Höcker B, Feneberg R, Köpf S, Weber LT, Waldherr R, Wühl E, Tönshoff B (2006) SRL-based immunosuppression vs CNI minimization in pediatric renal transplant recipients with chronic CNI nephrotoxicity. Pediatr Transplant 10:593-601
3. Valentini RP, Imam A, Warrier I, Ellis D, Ritchey AK, Ravindranath Y, Shapiro R, Mortiz ML (2006) Sirolimus rescue for tacrolimus-associated post-transplant hemolytic anemia. Pediatr Transplant 10:358-361
4. Garcia CD, Bittencourt VB, Alves AB, Garcia VD, Tumelero A, Antonello JS, Malheiros D (2006) Conversion to sirolimus in pediatric renal transplantation recipients. Transplant Proc 38:1901-1903
5. Alvarez-García O, Carbajo-Pérez E, García E, Gil H, Molinos I, Rodríguez J, Ordoñez FA, Santos F (2007) Rapamycin retards growth and causes marked alterations in the growth plate of young rats. Pediatr Nephrol 22:954-961
6. Holstein JH, Klein M, García P, Histing T, Culemann U, Pizanis A, Laschke MW, Scheuer C, Meier C, Schorr H, Pohlemann T, Menger MD (2008) Rapamycin affects early fracture healing in mice. Br J Pharmacol 154:1055-1062
7. Aoki MS, Miyabara EH, Soares AG, Saito ET, Moriscot AS (2006) mTOR pathway inhibition attenuates skeletal muscle growth induced by stretching. Cell Tissue Res 324:149-156
8. Sánchez CP, He YZ (2009) Bone growth during rapamycin therapy in young rats. BMC Pediatr 13:3
9. Hernández M, Castellet J, Narvaiza JL, Rincón JM, Ruiz I, Sánchez E, Sobradillo B, Zurimendi A (1988) Curvas y tablas de crecimiento. Fundación Orbegozo, Spain
10. Ariceta G, Besbas N, Johnson S, Karpman D, Landau D, Licht C, Loirat C, Pecoraro C, Taylor C, Van De Kar N, Van De Walle J, Zimmerhackl L (2009) Guideline for the investigation and initial therapy of diarrhea negative hemolytic uremic syndrome. Pediatr Nephrol 24:687-696
11. North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) (2008) Annual Report
12. El-Sabrout R, Weiss R, Butt F, Rashid I, Delaney V, Qadir M, Hanson P, Butt K (2002) Improved lipid profile and blood sugar control in pediatric renal transplant recipients using sirolimus-tacrolimus combination. Transplant Proc 34:1942-1943
13. Hymes LC, Warshaw BL (2005) Sirolimus in pediatric patients: Results in the first 6 months post-renal transplant. Pediatr Transplant 9:520-522
14. Franco A, Hernández D, Capdevilla P, Errasti P, Gonzalez M, Ruiz JC, Sanchez J, HUS-sirolimus Spanish study group (2003) De novo hemolytic-uremic syndrome/thrombotic microangiopathy in renal transplant patients receiving calcineurin inhibitors: Role of sirolimus. Transplant Proc 35:1764-1766
15. Guest G, Crosnier H, Chevallier T, Rappaport R, Broyer M, on behalf of the French Society of Pediatric Nephrology (1998) Effects of growth hormone in short children after renal transplantation. Pediatr Nephrol 12:437-446
16. Maxwell H, Rees L, for the British Association for Paediatric Nephrology (1998) Randomised controlled trial of recombinant human growth hormone in prepubertal and pubertal renal transplant recipients. Arch Dis Child 79:481-487
17. Fine RN, Stablein D, Cohen AH, Tejani A, Kohaut E (2002) Recombinant human growth hormone post-renal transplantation in children: A randomized controlled study of the NAPRTCS. Kidney Int 62:688-696