High prevalence of renal dysfunction in children after liver transplantation: Non-invasive diagnosis using a cystatin C-based equation

Nephrology Dialysis Transplantation

Volumn 26, Issue 4, 2011, Pages 1407-1412

  Brinkert, Florian ^a   Kemper, Markus J ^b   Briem Richter, Andrea ^c   Van Husen, Michael ^b   Treszl, Andras ^d   Ganschow, Rainer ^c  

^a Department of Pediatrics   (Germany)

^b Pediatric Nephrology   (Germany)

^c Pediatric Hepatology and Liver Transplantation   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

children; chronic kidney disease; cystatin C; liver transplantation; outcome

Indexed keywords

BASILIXIMAB; CYCLOSPORIN A; CYSTATIN C; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OPTORAL; PREDNISOLONE; TACROLIMUS; UNCLASSIFIED DRUG;

ADOLESCENT; ANALYTIC METHOD; ARTICLE; CHILD; CHILD HEALTH; CHRONIC KIDNEY DISEASE; CREATININE CLEARANCE; DISEASE SEVERITY; DRUG DOSE REDUCTION; FOLLOW UP; GLOMERULUS FILTRATION RATE; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LIVER TRANSPLANTATION; LONG TERM CARE; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; SINGLE DRUG DOSE;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CYSTATIN C; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; INFANT; KIDNEY FUNCTION TESTS; LIVER TRANSPLANTATION; MALE; PROGNOSIS; RENAL INSUFFICIENCY, CHRONIC; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE;

EID: 79953874227     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfq548     Document Type: Article

References (35)

1. Afonso RC, Hidalgo R, Zurstrassen MP et al. Impact of renal failure on liver transplantation survival. Transplant Proc 2008; 40: 808-810 (Pubitemid 351608664)
2. Ojo AO, Held PJ, Port FK et al. Chronic renal failure after transplantation of a nonrenal organ. N Engl J Med 2003; 349: 931-940 (Pubitemid 37064766)
3. Fine RN. Renal function following liver transplantation in children. Pediatr Transplant 2005; 9: 680-684 (Pubitemid 41413512)
4. McDiarmid SV. Renal function in pediatric liver transplant recipients. Transplantation 2001; 72: 561-562 (Pubitemid 32802733)
5. Aw MM, Samaroo B, Baker AJ et al. Calcineurin-inhibitor related nephrotoxicity-reversibility in paediatric liver transplant recipients. Transplantation 2001; 72: 746-749 (Pubitemid 32802766)
6. Herzog D, Martin S, Turpin S et al. Normal glomerular filtration rate in long-term follow-up of children after orthotopic liver transplantation. Transplantation 2006; 81: 672-677
7. Campbell KM, Yazigi N, Ryckman FC et al. High prevalence of renal dysfunction in long-term survivors after pediatric liver transplantation. J Pediatr 2006; 148: 475-480
8. Harambat J, Ranchin B, Dubourg L et al. Renal function in pediatric liver transplantation: a long-term follow-up study. Transplantation 2008; 86: 1028-1034
9. Bishop JR, Burniston MT, Barnfield MC et al. Renal function evaluated by measured GFR during follow-up in pediatric liver transplant recipients. Pediatr Transplant 2009; 13: 96-103
10. Mention K, Lahoche-Manucci A, Bonnevalle M et al. Renal function outcome in pediatric liver transplant recipients. Pediatr Transplant 2005; 9: 201-207 (Pubitemid 40476849)
11. Berg UB, Ericzon BG, Nemeth A. Renal function before and long after liver transplantation in children. Transplantation 2001; 72: 631-637 (Pubitemid 32802744)
12. Grubb A, Nyman U, Bjork J et al. Simple cystatin C-based prediction equations for glomerular filtration rate compared with the modification of diet in renal disease prediction equation for adults and the Schwartz and the Counahan-Barratt prediction equations for children. Clin Chem 2005; 51: 1420-1431 (Pubitemid 41060874)
13. Zappitelli M, Parvex P, Joseph L et al. Derivation and validation of cystatin C-based prediction equations for GFR in children. Am J Kidney Dis 2006; 48: 221-230 (Pubitemid 44069613)
14. Bouvet Y, Bouissou F, Coulais Y et al. GFR is better estimated by considering both serum cystatin C and creatinine levels. Pediatr Nephrol 2006; 21: 1299-1306 (Pubitemid 44203457)
15. Bokenkamp A, Domanetzki M, Zinck R et al. Cystatin C-a new marker of glomerular filtration rate in children independent of age and height. Pediatrics 1998; 101: 875-881 (Pubitemid 28204840)
16. Filler G, Lepage N. Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula? Pediatr Nephrol 2003; 18: 981-985 (Pubitemid 37236209)
17. Dharnidharka VR, Kwon C, Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis 2002; 40: 221-226 (Pubitemid 34827638)
18. Biancofiore G, Pucci L, Cerutti E et al. Cystatin C as a marker of renal function immediately after liver transplantation. Liver Transpl 2006; 12: 285-291 (Pubitemid 43273789)
19. Bharat W, Manlhiot C, McCrindle BW et al. The profile of renal function over time in a cohort of pediatric heart transplant recipients. Pediatr Transplant 2009; 13: 111-118
20. Schwartz GJ, Haycock GB, Edelmann CM Jr. et al. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 1976; 58: 259-263
21. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 2002; 39: S1-S266
22. Soergel M, Kirschstein M, Busch C et al. Oscillometric twenty-four-hour ambulatory blood pressure values in healthy children and adolescents: a multicenter trial including 1141 subjects. J Pediatr 1997; 130: 178-184 (Pubitemid 27495150)
23. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1: 307-310 (Pubitemid 16134762)
24. Cleveland WS, Grosse E. Computational methods for local regression. Stat Comput 1991; 1: 47-62
25. Ylinen EA, Ala-Houhala M, Harmoinen AP et al. Cystatin C as a marker for glomerular filtration rate in pediatric patients. Pediatr Nephrol 1999; 13: 506-509 (Pubitemid 29348706)
26. Pham-Huy A, Leonard M, Lepage N et al. Measuring glomerular filtration rate with cystatin C and beta-trace protein in children with spina bifida. J Urol 2003; 169: 2312-2315 (Pubitemid 36576789)
27. Samyn M, Cheeseman P, Bevis L et al. Cystatin C, an easy and reliable marker for assessment of renal dysfunction in children with liver disease and after liver transplantation. Liver Transpl 2005; 11: 344-349 (Pubitemid 40458409)
28. Sharma AP, Kathiravelu A, Nadarajah R et al. Body mass does not have a clinically relevant effect on cystatin C eGFR in children. Nephrol Dial Transplant 2009; 24: 470-474
29. Evans HM, McKiernan PJ, Kelly DA. Mycophenolate mofetil for renal dysfunction after pediatric liver transplantation. Transplantation 2005; 79: 1575-1580 (Pubitemid 40847590)
30. Tonshoff B, Hocker B. Treatment strategies in pediatric solid organ transplant recipients with calcineurin inhibitor-induced nephrotoxicity. Pediatr Transplant 2006; 10: 721-729 (Pubitemid 44186295)
31. Sarwal M, Pascual J. Immunosuppression minimization in pediatric transplantation. Am J Transplant 2007; 7: 2227-2235 (Pubitemid 47347859)
32. Loo RM, Ariyarajah V, Oh C et al. Comparison between effects of cyclosporine and tacrolimus on glomerular filtration rate in pediatric post-orthotopic liver transplant patients. Pediatr Transplant 2006; 10: 55-59
33. Querfeld U. The clinical significance of vascular calcification in young patients with end-stage renal disease. Pediatr Nephrol 2004; 19: 478-484 (Pubitemid 38594283)
34. Textor SC, Taler SJ, Canzanello VJ et al. Posttransplantation hypertension related to calcineurin inhibitors. Liver Transpl 2000; 6: 521-530
35. Hayashi T, Kato H, Kaneko M et al. Management of arterial hypertension occurring early after living donor liver transplantation in children: report of three cases and review of the literature. Pediatr Cardiol 2009; 30: 1161-1165