-
1
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
-
Filipowicz W, Bhattacharyya SN, Sonenberg N, (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9: 102-114.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
3
-
-
79951979718
-
microRNAs: Master regulators as potential therapeutics in cancer
-
Garofalo M, Croce CM, (2011) microRNAs: Master regulators as potential therapeutics in cancer. Annu Rev Pharmacol Toxicol 51: 25-43.
-
(2011)
Annu Rev Pharmacol Toxicol
, vol.51
, pp. 25-43
-
-
Garofalo, M.1
Croce, C.M.2
-
4
-
-
78650034475
-
miRNAs in human cancer
-
Farazi TA, Spitzer JI, Morozov P, Tuschl T, (2011) miRNAs in human cancer. J Pathol 223: 102-115.
-
(2011)
J Pathol
, vol.223
, pp. 102-115
-
-
Farazi, T.A.1
Spitzer, J.I.2
Morozov, P.3
Tuschl, T.4
-
5
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T, (2007) Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 39: 673-677.
-
(2007)
Nat Genet
, vol.39
, pp. 673-677
-
-
Kumar, M.S.1
Lu, J.2
Mercer, K.L.3
Golub, T.R.4
Jacks, T.5
-
6
-
-
33747334621
-
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
-
Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, et al. (2006) Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev 20: 2202-2207.
-
(2006)
Genes Dev
, vol.20
, pp. 2202-2207
-
-
Thomson, J.M.1
Newman, M.2
Parker, J.S.3
Morin-Kensicki, E.M.4
Wright, T.5
-
8
-
-
78650639749
-
Emerging complexity of microRNA generation cascades
-
Suzuki HI, Miyazono K, (2011) Emerging complexity of microRNA generation cascades. J Biochem 149: 15-25.
-
(2011)
J Biochem
, vol.149
, pp. 15-25
-
-
Suzuki, H.I.1
Miyazono, K.2
-
9
-
-
77951964981
-
Posttranscriptional regulation of microRNA biogenesis in animals
-
Siomi H, Siomi MC, (2010) Posttranscriptional regulation of microRNA biogenesis in animals. Mol Cell 38: 323-332.
-
(2010)
Mol Cell
, vol.38
, pp. 323-332
-
-
Siomi, H.1
Siomi, M.C.2
-
10
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol J, Loedige I, Filipowicz W, (2010) The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11: 597-610.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
11
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
Davis BN, Hilyard AC, Lagna G, Hata A, (2008) SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454: 56-61.
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
12
-
-
70350013561
-
Maturation of microRNA is hormonally regulated by a nuclear receptor
-
Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, et al. (2009) Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell 36: 340-347.
-
(2009)
Mol Cell
, vol.36
, pp. 340-347
-
-
Yamagata, K.1
Fujiyama, S.2
Ito, S.3
Ueda, T.4
Murata, T.5
-
13
-
-
67649277689
-
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
-
Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, et al. (2009) The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 459: 1010-1014.
-
(2009)
Nature
, vol.459
, pp. 1010-1014
-
-
Trabucchi, M.1
Briata, P.2
Garcia-Mayoral, M.3
Haase, A.D.4
Filipowicz, W.5
-
14
-
-
67749143728
-
Modulation of microRNA processing by p53
-
Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, et al. (2009) Modulation of microRNA processing by p53. Nature 460: 529-533.
-
(2009)
Nature
, vol.460
, pp. 529-533
-
-
Suzuki, H.I.1
Yamagata, K.2
Sugimoto, K.3
Iwamoto, T.4
Kato, S.5
-
17
-
-
79957611696
-
Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas
-
Kwak HJ, Kim YJ, Chun KR, Woo YM, Park SJ, et al. (2011) Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas. Oncogene 30: 2433-2442.
-
(2011)
Oncogene
, vol.30
, pp. 2433-2442
-
-
Kwak, H.J.1
Kim, Y.J.2
Chun, K.R.3
Woo, Y.M.4
Park, S.J.5
-
18
-
-
79955007479
-
Isolation and characterization of plant protein complexes by mass spectrometry
-
Pflieger D, Bigeard J, Hirt H, (2011) Isolation and characterization of plant protein complexes by mass spectrometry. Proteomics 11: 1824-1833.
-
(2011)
Proteomics
, vol.11
, pp. 1824-1833
-
-
Pflieger, D.1
Bigeard, J.2
Hirt, H.3
-
19
-
-
77955930508
-
Interaction proteomics: characterization of protein complexes using tandem affinity purification-mass spectrometry
-
Volkel P, Le Faou P, Angrand PO, (2010) Interaction proteomics: characterization of protein complexes using tandem affinity purification-mass spectrometry. Biochem Soc Trans 38: 883-887.
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 883-887
-
-
Volkel, P.1
Le Faou, P.2
Angrand, P.O.3
-
20
-
-
63049110938
-
A study of microRNAs in silico and in vivo: bioimaging of microRNA biogenesis and regulation
-
Kim S, Hwang do W, Lee DS, (2009) A study of microRNAs in silico and in vivo: bioimaging of microRNA biogenesis and regulation. FEBS J 276: 2165-2174.
-
(2009)
FEBS J
, vol.276
, pp. 2165-2174
-
-
Kim, S.1
do Hwang, W.2
Lee, D.S.3
-
21
-
-
34447115822
-
The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a
-
Guil S, Caceres JF, (2007) The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol 14: 591-596.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 591-596
-
-
Guil, S.1
Caceres, J.F.2
-
22
-
-
77955425756
-
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis
-
Michlewski G, Caceres JF, (2010) Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat Struct Mol Biol 17: 1011-1018.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1011-1018
-
-
Michlewski, G.1
Caceres, J.F.2
-
23
-
-
40849108663
-
Selective blockade of microRNA processing by Lin28
-
Viswanathan SR, Daley GQ, Gregory RI, (2008) Selective blockade of microRNA processing by Lin28. Science 320: 97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
24
-
-
75149177193
-
LIN28B confers radio-resistance through the posttranscriptional control of KRAS
-
Jeong SH, Wu HG, Park WY, (2009) LIN28B confers radio-resistance through the posttranscriptional control of KRAS. Exp Mol Med 41: 912-918.
-
(2009)
Exp Mol Med
, vol.41
, pp. 912-918
-
-
Jeong, S.H.1
Wu, H.G.2
Park, W.Y.3
-
25
-
-
78549261109
-
Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells
-
Yang X, Lin X, Zhong X, Kaur S, Li N, et al. (2010) Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells. Cancer Res 70: 9463-9472.
-
(2010)
Cancer Res
, vol.70
, pp. 9463-9472
-
-
Yang, X.1
Lin, X.2
Zhong, X.3
Kaur, S.4
Li, N.5
-
26
-
-
53949088050
-
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
-
Heo I, Joo C, Cho J, Ha M, Han J, et al. (2008) Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 32: 276-284.
-
(2008)
Mol Cell
, vol.32
, pp. 276-284
-
-
Heo, I.1
Joo, C.2
Cho, J.3
Ha, M.4
Han, J.5
-
27
-
-
79951580697
-
The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei
-
Furia A, Moscato M, Cali G, Pizzo E, Confalone E, et al. (2011) The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei. FEBS Lett 585: 613-617.
-
(2011)
FEBS Lett
, vol.585
, pp. 613-617
-
-
Furia, A.1
Moscato, M.2
Cali, G.3
Pizzo, E.4
Confalone, E.5
-
28
-
-
79953038262
-
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
-
Hollander MC, Blumenthal GM, Dennis PA, (2011) PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat Rev Cancer 11: 289-301.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 289-301
-
-
Hollander, M.C.1
Blumenthal, G.M.2
Dennis, P.A.3
-
29
-
-
66149141021
-
PTEN and the PI3-kinase pathway in cancer
-
Chalhoub N, Baker SJ, (2009) PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol 4: 127-150.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 127-150
-
-
Chalhoub, N.1
Baker, S.J.2
-
30
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, et al. (2007) MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658.
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
-
31
-
-
65449119905
-
Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes
-
Vinciguerra M, Sgroi A, Veyrat-Durebex C, Rubbia-Brandt L, Buhler LH, et al. (2009) Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes. Hepatology 49: 1176-1184.
-
(2009)
Hepatology
, vol.49
, pp. 1176-1184
-
-
Vinciguerra, M.1
Sgroi, A.2
Veyrat-Durebex, C.3
Rubbia-Brandt, L.4
Buhler, L.H.5
-
33
-
-
78651482046
-
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
-
Song MS, Carracedo A, Salmena L, Song SJ, Egia A, et al. (2011) Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner. Cell 144: 187-199.
-
(2011)
Cell
, vol.144
, pp. 187-199
-
-
Song, M.S.1
Carracedo, A.2
Salmena, L.3
Song, S.J.4
Egia, A.5
-
34
-
-
53649106156
-
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
-
Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, et al. (2008) The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network. Nature 455: 813-817.
-
(2008)
Nature
, vol.455
, pp. 813-817
-
-
Song, M.S.1
Salmena, L.2
Carracedo, A.3
Egia, A.4
Lo-Coco, F.5
-
35
-
-
33845977965
-
Ubiquitination regulates PTEN nuclear import and tumor suppression
-
Trotman LC, Wang X, Alimonti A, Chen Z, Teruya-Feldstein J, et al. (2007) Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell 128: 141-156.
-
(2007)
Cell
, vol.128
, pp. 141-156
-
-
Trotman, L.C.1
Wang, X.2
Alimonti, A.3
Chen, Z.4
Teruya-Feldstein, J.5
-
36
-
-
33746990186
-
Mechanistic insights into maintenance of high p53 acetylation by PTEN
-
Li AG, Piluso LG, Cai X, Wei G, Sellers WR, et al. (2006) Mechanistic insights into maintenance of high p53 acetylation by PTEN. Mol Cell 23: 575-587.
-
(2006)
Mol Cell
, vol.23
, pp. 575-587
-
-
Li, A.G.1
Piluso, L.G.2
Cai, X.3
Wei, G.4
Sellers, W.R.5
-
37
-
-
33845999615
-
Essential role for nuclear PTEN in maintaining chromosomal integrity
-
Shen WH, Balajee AS, Wang J, Wu H, Eng C, et al. (2007) Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell 128: 157-170.
-
(2007)
Cell
, vol.128
, pp. 157-170
-
-
Shen, W.H.1
Balajee, A.S.2
Wang, J.3
Wu, H.4
Eng, C.5
-
39
-
-
49249092223
-
The leucine-rich repeat structure
-
Bella J, Hindle KL, McEwan PA, Lovell SC, (2008) The leucine-rich repeat structure. Cell Mol Life Sci 65: 2307-2333.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2307-2333
-
-
Bella, J.1
Hindle, K.L.2
McEwan, P.A.3
Lovell, S.C.4
-
40
-
-
80052504962
-
Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP
-
Teplova M, Wohlbold L, Khin NW, Izaurralde E, Patel DJ, (2011) Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nat Struct Mol Biol 18: 990-998.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 990-998
-
-
Teplova, M.1
Wohlbold, L.2
Khin, N.W.3
Izaurralde, E.4
Patel, D.J.5
-
42
-
-
34247876168
-
DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs
-
Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, et al. (2007) DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol 9: 604-611.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 604-611
-
-
Fukuda, T.1
Yamagata, K.2
Fujiyama, S.3
Matsumoto, T.4
Koshida, I.5
-
43
-
-
67650590937
-
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation
-
Gruber JJ, Zatechka DS, Sabin LR, Yong J, Lum JJ, et al. (2009) Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell 138: 328-339.
-
(2009)
Cell
, vol.138
, pp. 328-339
-
-
Gruber, J.J.1
Zatechka, D.S.2
Sabin, L.R.3
Yong, J.4
Lum, J.J.5
-
44
-
-
67650638926
-
Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila
-
Sabin LR, Zhou R, Gruber JJ, Lukinova N, Bambina S, et al. (2009) Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila. Cell 138: 340-351.
-
(2009)
Cell
, vol.138
, pp. 340-351
-
-
Sabin, L.R.1
Zhou, R.2
Gruber, J.J.3
Lukinova, N.4
Bambina, S.5
-
45
-
-
77950357450
-
A splicing-independent function of SF2/ASF in microRNA processing
-
Wu H, Sun S, Tu K, Gao Y, Xie B, et al. (2010) A splicing-independent function of SF2/ASF in microRNA processing. Mol Cell 38: 67-77.
-
(2010)
Mol Cell
, vol.38
, pp. 67-77
-
-
Wu, H.1
Sun, S.2
Tu, K.3
Gao, Y.4
Xie, B.5
-
46
-
-
79960066418
-
Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy
-
Rau F, Freyermuth F, Fugier C, Villemin JP, Fischer MC, et al. (2011) Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy. Nat Struct Mol Biol 18: 840-845.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 840-845
-
-
Rau, F.1
Freyermuth, F.2
Fugier, C.3
Villemin, J.P.4
Fischer, M.C.5
-
47
-
-
34547655427
-
CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response
-
Kim H, Huang J, Chen J, (2007) CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response. Nat Struct Mol Biol 14: 710-715.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 710-715
-
-
Kim, H.1
Huang, J.2
Chen, J.3
-
48
-
-
33749662940
-
Opposing polymerase-deadenylase activities regulate cytoplasmic polyadenylation
-
Kim JH, Richter JD, (2006) Opposing polymerase-deadenylase activities regulate cytoplasmic polyadenylation. Mol Cell 24: 173-183.
-
(2006)
Mol Cell
, vol.24
, pp. 173-183
-
-
Kim, J.H.1
Richter, J.D.2
-
49
-
-
0034607554
-
Protein-protein interaction among hnRNPs shuttling between nucleus and cytoplasm
-
Kim JH, Hahm B, Kim YK, Choi M, Jang SK, (2000) Protein-protein interaction among hnRNPs shuttling between nucleus and cytoplasm. J Mol Biol 298: 395-405.
-
(2000)
J Mol Biol
, vol.298
, pp. 395-405
-
-
Kim, J.H.1
Hahm, B.2
Kim, Y.K.3
Choi, M.4
Jang, S.K.5
-
50
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, et al. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425: 415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
-
51
-
-
33845760911
-
BiP internal ribosomal entry site activity is controlled by heat-induced interaction of NSAP1
-
Cho S, Park SM, Kim TD, Kim JH, Kim KT, et al. (2007) BiP internal ribosomal entry site activity is controlled by heat-induced interaction of NSAP1. Mol Cell Biol 27: 368-383.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 368-383
-
-
Cho, S.1
Park, S.M.2
Kim, T.D.3
Kim, J.H.4
Kim, K.T.5
-
52
-
-
13444283592
-
Polypyrimidine tract-binding protein enhances the internal ribosomal entry site-dependent translation of p27Kip1 mRNA and modulates transition from G1 to S phase
-
Cho S, Kim JH, Back SH, Jang SK, (2005) Polypyrimidine tract-binding protein enhances the internal ribosomal entry site-dependent translation of p27Kip1 mRNA and modulates transition from G1 to S phase. Mol Cell Biol 25: 1283-1297.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1283-1297
-
-
Cho, S.1
Kim, J.H.2
Back, S.H.3
Jang, S.K.4
-
53
-
-
42949179593
-
In vitro and in vivo assays for the activity of Drosha complex
-
Lee Y, Kim VN, (2007) In vitro and in vivo assays for the activity of Drosha complex. Methods Enzymol 427: 89-106.
-
(2007)
Methods Enzymol
, vol.427
, pp. 89-106
-
-
Lee, Y.1
Kim, V.N.2
|