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Volumn 20, Issue 11, 2013, Pages 1465-1474

P53 regulates a non-apoptotic death induced by ROS

Author keywords

apoptosis; p53; PARP; ROS

Indexed keywords

CASPASE 3; DAUNORUBICIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

EID: 84885399978     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.52     Document Type: Article
Times cited : (118)

References (43)
  • 2
    • 84859169877 scopus 로고    scopus 로고
    • The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
    • Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012; 483: 603-607.
    • (2012) Nature , vol.483 , pp. 603-607
    • Barretina, J.1    Caponigro, G.2    Stransky, N.3    Venkatesan, K.4    Margolin, A.A.5    Kim, S.6
  • 3
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer research 1994; 54: 4855-4878.
    • (1994) Cancer Research , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 6
    • 0842278331 scopus 로고    scopus 로고
    • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    • Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science (New York, N.Y 2004; 303: 1010-1014.
    • (2004) Science (New York N.Y , vol.303 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3    Droin, N.M.4    Newmeyer, D.D.5
  • 9
    • 33749830382 scopus 로고    scopus 로고
    • Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint
    • Macip S, Kosoy A, Lee SW, O'Connell MJ, Aaronson SA. Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint. Oncogene 2006; 25: 6037-6047.
    • (2006) Oncogene , vol.25 , pp. 6037-6047
    • MacIp, S.1    Kosoy, A.2    Lee, S.W.3    O'Connell, M.J.4    Aaronson, S.A.5
  • 11
    • 10344234720 scopus 로고    scopus 로고
    • Poly(ADP-ribose) is required for spindle assembly and structure
    • Chang P, Jacobson MK, Mitchison TJ. Poly(ADP-ribose) is required for spindle assembly and structure. Nature 2004; 432: 645-649.
    • (2004) Nature , vol.432 , pp. 645-649
    • Chang, P.1    Jacobson, M.K.2    Mitchison, T.J.3
  • 13
    • 79960703030 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 inhibition: Preclinical and clinical development of synthetic lethality
    • Leung M, Rosen D, Fields S, Cesano A, Budman DR. Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development of synthetic lethality. Mol Med (Cambridge) Mass 2011; 17: 854-862.
    • (2011) Mol Med (Cambridge) Mass , vol.17 , pp. 854-862
    • Leung, M.1    Rosen, D.2    Fields, S.3    Cesano, A.4    Budman, D.R.5
  • 15
    • 24744447821 scopus 로고    scopus 로고
    • The role of poly(ADP-ribose) in the DNA damage signaling network
    • Malanga M, Althaus FR. The role of poly(ADP-ribose) in the DNA damage signaling network. Biochem Cell Biol 2005; 83: 354-364.
    • (2005) Biochem Cell Biol , vol.83 , pp. 354-364
    • Malanga, M.1    Althaus, F.R.2
  • 16
    • 0032533856 scopus 로고    scopus 로고
    • Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: Covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85, 000 proteolytic fragment
    • Kumari SR, Mendoza-Alvarez H, Alvarez-Gonzalez R. Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85, 000 proteolytic fragment. Cancer Res 1998; 58: 5075-5078.
    • (1998) Cancer Res , vol.58 , pp. 5075-5078
    • Kumari, S.R.1    Mendoza-Alvarez, H.2    Alvarez-Gonzalez, R.3
  • 18
    • 40949092052 scopus 로고    scopus 로고
    • Genomic maintenance: The p53 poly(ADP-ribosyl)ation connection
    • Alvarez-Gonzalez R. Genomic maintenance: the p53 poly(ADP-ribosyl)ation connection. Sci STKE 2007; 2007: pe68.
    • (2007) Sci STKE , vol.2007
    • Alvarez-Gonzalez, R.1
  • 20
    • 2642536197 scopus 로고    scopus 로고
    • Alkylating DNA damage stimulates a regulated form of necrotic cell death
    • Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004; 18: 1272-1282.
    • (2004) Genes Dev , vol.18 , pp. 1272-1282
    • Zong, W.X.1    Ditsworth, D.2    Bauer, D.E.3    Wang, Z.Q.4    Thompson, C.B.5
  • 21
  • 22
    • 34347344991 scopus 로고    scopus 로고
    • Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis
    • Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J et al. Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol Cell Biol 2007; 27: 4844-4862.
    • (2007) Mol Cell Biol , vol.27 , pp. 4844-4862
    • Moubarak, R.S.1    Yuste, V.J.2    Artus, C.3    Bouharrour, A.4    Greer, P.A.5    Menissier-De Murcia, J.6
  • 23
    • 85028106161 scopus 로고    scopus 로고
    • Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2 + fluxes in oxidative cell death
    • Blenn C, Wyrsch P, Bader J, Bollhalder M, Althaus FR. Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2 + fluxes in oxidative cell death. Cell Mol Life Sci 2011; 68: 1455-1466.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 1455-1466
    • Blenn, C.1    Wyrsch, P.2    Bader, J.3    Bollhalder, M.4    Althaus, F.R.5
  • 24
    • 0033598713 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
    • Ha HC, Snyder SH. Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc Natl Acad Sci USA 1999; 96: 13978-13982.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13978-13982
    • Ha, H.C.1    Snyder, S.H.2
  • 25
    • 29944438881 scopus 로고    scopus 로고
    • Necrotic death as a cell fate
    • Zong WX, Thompson CB. Necrotic death as a cell fate. Genes Dev 2006; 20: 1-15.
    • (2006) Genes Dev , vol.20 , pp. 1-15
    • Zong, W.X.1    Thompson, C.B.2
  • 26
    • 0035012606 scopus 로고    scopus 로고
    • DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression
    • Tong WM, Hande MP, Lansdorp PM, Wang ZQ. DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression. Mol Cell Biol 2001; 21: 4046-4054.
    • (2001) Mol Cell Biol , vol.21 , pp. 4046-4054
    • Tong, W.M.1    Hande, M.P.2    Lansdorp, P.M.3    Wang, Z.Q.4
  • 27
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001; 15: 1481-1486.
    • (2001) Genes Dev , vol.15 , pp. 1481-1486
    • Zong, W.X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 28
    • 0034523818 scopus 로고    scopus 로고
    • Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
    • Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 2000; 7: 1166-1173.
    • (2000) Cell Death Differ , vol.7 , pp. 1166-1173
    • Korsmeyer, S.J.1    Wei, M.C.2    Saito, M.3    Weiler, S.4    Oh, K.J.5    Schlesinger, P.H.6
  • 29
    • 84862675016 scopus 로고    scopus 로고
    • P53 opens the mitochondrial permeability transition pore to trigger necrosis
    • Vaseva AV, Marchenko ND, Ji K, Tsirka SE, Holzmann S, Moll UM. p53 opens the mitochondrial permeability transition pore to trigger necrosis. Cell 2012; 149: 1536-1548.
    • (2012) Cell , vol.149 , pp. 1536-1548
    • Vaseva, A.V.1    Marchenko, N.D.2    Ji, K.3    Tsirka, S.E.4    Holzmann, S.5    Moll, U.M.6
  • 31
    • 0030915587 scopus 로고    scopus 로고
    • Intracellular ATP levels determine cell death fate by apoptosis or necrosis
    • Eguchi Y, Shimizu S, Tsujimoto Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 1997; 57: 1835-1840.
    • (1997) Cancer Res , vol.57 , pp. 1835-1840
    • Eguchi, Y.1    Shimizu, S.2    Tsujimoto, Y.3
  • 32
    • 77955616572 scopus 로고    scopus 로고
    • Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4 + CD8 + thymocytes
    • Ryan JA, Brunelle JK, Letai A. Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4 + CD8 + thymocytes. Proc Natl Acad Sci USA 2010; 107: 12895-12900.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 12895-12900
    • Ryan, J.A.1    Brunelle, J.K.2    Letai, A.3
  • 33
    • 84255177532 scopus 로고    scopus 로고
    • Who put the 'A' in Atg12: Autophagy or apoptosis?
    • Chonghaile TN, Letai A. Who put the 'A' in Atg12: autophagy or apoptosis? Mol Cell 2011; 44: 844-845.
    • (2011) Mol Cell , vol.44 , pp. 844-845
    • Chonghaile, T.N.1    Letai, A.2
  • 36
    • 59149097561 scopus 로고    scopus 로고
    • The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage
    • Tu HC, Ren D, Wang GX, Chen DY, Westergard TD, Kim H et al. The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage. Proc Natl Acad Sci USA 2009; 106: 1093-1098.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1093-1098
    • Tu, H.C.1    Ren, D.2    Wang, G.X.3    Chen, D.Y.4    Westergard, T.D.5    Kim, H.6
  • 37
    • 70350225573 scopus 로고    scopus 로고
    • BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells
    • Mani M, Carrasco DE, Zhang Y, Takada K, Gatt ME, Dutta-Simmons J et al. BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells. Cancer Res 2009; 69: 7577-7586.
    • (2009) Cancer Res , vol.69 , pp. 7577-7586
    • Mani, M.1    Carrasco, D.E.2    Zhang, Y.3    Takada, K.4    Gatt, M.E.5    Dutta-Simmons, J.6
  • 38
    • 0028294898 scopus 로고
    • Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal
    • Gottlieb E, Haffner R, von Ruden T, Wagner EF, Oren M. Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO J 1994; 13: 1368-1374.
    • (1994) EMBO J , vol.13 , pp. 1368-1374
    • Gottlieb, E.1    Haffner, R.2    Von Ruden, T.3    Wagner, E.F.4    Oren, M.5
  • 39
    • 0027451668 scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993; 74: 957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 40
    • 67651210858 scopus 로고    scopus 로고
    • SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly (ADP-ribose) polymerase 1
    • Rajamohan SB, Pillai VB, Gupta M, Sundaresan NR, Birukov KG, Samant S et al. SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly (ADP-ribose) polymerase 1. Mol Cell Biol 2009; 29: 4116-4129.
    • (2009) Mol Cell Biol , vol.29 , pp. 4116-4129
    • Rajamohan, S.B.1    Pillai, V.B.2    Gupta, M.3    Sundaresan, N.R.4    Birukov, K.G.5    Samant, S.6
  • 41
    • 0028169994 scopus 로고
    • P53-dependent apoptosis suppresses tumor growth and progression in vivo
    • Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T et al. p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 1994; 78: 703-711.
    • (1994) Cell , vol.78 , pp. 703-711
    • Symonds, H.1    Krall, L.2    Remington, L.3    Saenz-Robles, M.4    Lowe, S.5    Jacks, T.6
  • 43
    • 39749164505 scopus 로고    scopus 로고
    • Expression and purification of recombinant annexin v for the detection of membrane alterations on apoptotic cells
    • Brumatti G, Sheridan C, Martin SJ. Expression and purification of recombinant annexin V for the detection of membrane alterations on apoptotic cells. Methods 2008; 44: 235-240.
    • (2008) Methods , vol.44 , pp. 235-240
    • Brumatti, G.1    Sheridan, C.2    Martin, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.