메뉴 건너뛰기




Volumn 532, Issue 1, 2013, Pages 146-151

PCB-77 disturbs iron homeostasis through regulating hepcidin gene expression

Author keywords

Hepatocytes; Hepcidin; Iron homeostasis; PCB 77

Indexed keywords

3,3',4,4' TETRACHLOROBIPHENYL; HEPCIDIN; IRON; POLYCHLORINATED BIPHENYL;

EID: 84885371417     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.09.023     Document Type: Article
Times cited : (16)

References (54)
  • 1
    • 63449103712 scopus 로고    scopus 로고
    • BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
    • Andriopoulos B., et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat. Genet. 2009, 41:482-487.
    • (2009) Nat. Genet. , vol.41 , pp. 482-487
    • Andriopoulos, B.1
  • 2
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker S.D., et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N. Engl. J. Med. 2009, 361:2436-2448.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2436-2448
    • Anker, S.D.1
  • 3
    • 0033983555 scopus 로고    scopus 로고
    • Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk
    • Aronson K.J., et al. Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk. Cancer Epidemiol. Biomark. Prev. 2000, 9:55-63.
    • (2000) Cancer Epidemiol. Biomark. Prev. , vol.9 , pp. 55-63
    • Aronson, K.J.1
  • 4
    • 84859218438 scopus 로고    scopus 로고
    • Interleukin-6 contributes to hepcidin mRNA increase in response to exercise
    • Banzet S., Sanchez H., Chapot R., Bigard X., Vaulont S., Koulmann N. Interleukin-6 contributes to hepcidin mRNA increase in response to exercise. Cytokine 2012, 58:158-161.
    • (2012) Cytokine , vol.58 , pp. 158-161
    • Banzet, S.1    Sanchez, H.2    Chapot, R.3    Bigard, X.4    Vaulont, S.5    Koulmann, N.6
  • 5
    • 33748265283 scopus 로고    scopus 로고
    • Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH
    • Bekri S., et al. Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH. Gastroenterology 2006, 131:788-796.
    • (2006) Gastroenterology , vol.131 , pp. 788-796
    • Bekri, S.1
  • 6
    • 67449123256 scopus 로고    scopus 로고
    • Brain iron homeostasis and neurodegenerative disease
    • Benarroch E.E. Brain iron homeostasis and neurodegenerative disease. Neurology 2009, 72:1436-1440.
    • (2009) Neurology , vol.72 , pp. 1436-1440
    • Benarroch, E.E.1
  • 7
    • 0028025046 scopus 로고
    • Endocrine effects of prenatal exposure to PCBs, dioxins, and other xenobiotics: implications for policy and future research
    • Birnbaum L.S. Endocrine effects of prenatal exposure to PCBs, dioxins, and other xenobiotics: implications for policy and future research. Environ. Heal. Perspect. 1994, 102:676.
    • (1994) Environ. Heal. Perspect. , vol.102 , pp. 676
    • Birnbaum, L.S.1
  • 10
    • 0001169826 scopus 로고
    • Inhibition of growth and photosynthesis in Chlorella pyrenoidosa by a polychlorinated biphenyl and several insecticides
    • COLE D.R., PLAPP F.W. Inhibition of growth and photosynthesis in Chlorella pyrenoidosa by a polychlorinated biphenyl and several insecticides. Environ. Entomol. 1974, 3:217-220.
    • (1974) Environ. Entomol. , vol.3 , pp. 217-220
    • Cole, D.R.1    Plapp, F.W.2
  • 11
    • 84868526205 scopus 로고    scopus 로고
    • Hepcidin and the iron-infection axis
    • Drakesmith H., Prentice A.M. Hepcidin and the iron-infection axis. Science 2012, 338:768-772.
    • (2012) Science , vol.338 , pp. 768-772
    • Drakesmith, H.1    Prentice, A.M.2
  • 12
    • 77956647381 scopus 로고    scopus 로고
    • Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease
    • Duce J.A., et al. Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease. Cell 2010, 142:857-867.
    • (2010) Cell , vol.142 , pp. 857-867
    • Duce, J.A.1
  • 13
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Elizabeta Nemeth M.S.T., et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004, 306:2090-2093.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Elizabeta Nemeth, M.S.T.1
  • 14
    • 84860574815 scopus 로고    scopus 로고
    • Iron sensing and signalling
    • Evstatiev R., Gasche C. Iron sensing and signalling. Gut 2012, 61:933-952.
    • (2012) Gut , vol.61 , pp. 933-952
    • Evstatiev, R.1    Gasche, C.2
  • 15
    • 84885390122 scopus 로고    scopus 로고
    • Clinical meaning of serum ferritin, iron in chronic hepatitic B [J]
    • Fei S., Fengqun Z., Chunji L. Clinical meaning of serum ferritin, iron in chronic hepatitic B [J]. J. Xi'an Jiaotong Univ. (Med. Sci.) 2006, 3:024.
    • (2006) J. Xi'an Jiaotong Univ. (Med. Sci.) , vol.3 , pp. 024
    • Fei, S.1    Fengqun, Z.2    Chunji, L.3
  • 16
    • 67649862044 scopus 로고    scopus 로고
    • Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
    • Ferrucci L., et al. Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Br. J. Cancer 2009, 101:178-184.
    • (2009) Br. J. Cancer , vol.101 , pp. 178-184
    • Ferrucci, L.1
  • 17
    • 0018903316 scopus 로고
    • Effect of various iron chelating agents on DNA synthesis in human cells
    • Ganeshaguru K., Hoffbrand A.V., Grady R.W., Cerami A. Effect of various iron chelating agents on DNA synthesis in human cells. Biochem. Pharmacol. 1980, 29:1275-1279.
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 1275-1279
    • Ganeshaguru, K.1    Hoffbrand, A.V.2    Grady, R.W.3    Cerami, A.4
  • 18
    • 79952400561 scopus 로고    scopus 로고
    • The role of hepcidin in iron homeostasis
    • Springer
    • Ganz T. The role of hepcidin in iron homeostasis. Iron Deficiency and Overload 2010, 51-64. Springer.
    • (2010) Iron Deficiency and Overload , pp. 51-64
    • Ganz, T.1
  • 19
    • 84859417866 scopus 로고    scopus 로고
    • The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders
    • Ganz T., Nemeth E. The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders. ASH Education Program Book 2011 2011, 538-542.
    • (2011) ASH Education Program Book 2011 , pp. 538-542
    • Ganz, T.1    Nemeth, E.2
  • 20
    • 31744441673 scopus 로고    scopus 로고
    • Non haematological effects of iron deficiency - a perspective
    • Ghosh K. Non haematological effects of iron deficiency - a perspective. Indian J. Med. Sci. 2006, 60:30-37.
    • (2006) Indian J. Med. Sci. , vol.60 , pp. 30-37
    • Ghosh, K.1
  • 21
    • 0022368257 scopus 로고    scopus 로고
    • Severe hemochromatosis: the predominant clinical manifestation of congenital dyserythropoietic anemia type 2
    • Halpern Z., Rahmani R., Levo Y. Severe hemochromatosis: the predominant clinical manifestation of congenital dyserythropoietic anemia type 2. Acta Haematol. 2009, 74:178-180.
    • (2009) Acta Haematol. , vol.74 , pp. 178-180
    • Halpern, Z.1    Rahmani, R.2    Levo, Y.3
  • 22
    • 32544442167 scopus 로고    scopus 로고
    • The role of laser fluence in cell viability, proliferation, and membrane integrity of wounded human skin fibroblasts following helium-neon laser irradiation
    • Hawkins D.H., Abrahamse H. The role of laser fluence in cell viability, proliferation, and membrane integrity of wounded human skin fibroblasts following helium-neon laser irradiation. Lasers Surg. Med. 2006, 38:74-83.
    • (2006) Lasers Surg. Med. , vol.38 , pp. 74-83
    • Hawkins, D.H.1    Abrahamse, H.2
  • 23
    • 84868193427 scopus 로고    scopus 로고
    • Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element
    • Hou Y., et al. Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element. Gene 2012, 511:398-403.
    • (2012) Gene , vol.511 , pp. 398-403
    • Hou, Y.1
  • 24
    • 0038711587 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
    • Jeong S.Y., David S. Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system. J. Biol. Chem. 2003, 278:27144-27148.
    • (2003) J. Biol. Chem. , vol.278 , pp. 27144-27148
    • Jeong, S.Y.1    David, S.2
  • 25
    • 36549032729 scopus 로고    scopus 로고
    • Dietary animal-derived iron and fat intake and breast cancer risk in the Shanghai Breast Cancer Study
    • Kallianpur A.R., et al. Dietary animal-derived iron and fat intake and breast cancer risk in the Shanghai Breast Cancer Study. Breast Cancer Res. Treat. 2008, 107:123-132.
    • (2008) Breast Cancer Res. Treat. , vol.107 , pp. 123-132
    • Kallianpur, A.R.1
  • 26
    • 0034001883 scopus 로고    scopus 로고
    • Both iron deficiency and daily iron supplements increase lipid peroxidation in rats
    • Knutson M.D., Walter P.B., Ames B.N., Viteri F.E. Both iron deficiency and daily iron supplements increase lipid peroxidation in rats. J. Nutr. 2000, 130:621-628.
    • (2000) J. Nutr. , vol.130 , pp. 621-628
    • Knutson, M.D.1    Walter, P.B.2    Ames, B.N.3    Viteri, F.E.4
  • 27
    • 0030768496 scopus 로고    scopus 로고
    • Structure-activity relationships of potentially neurotoxic PCB congeners in the rat
    • Kodavanti P., Tilson H. Structure-activity relationships of potentially neurotoxic PCB congeners in the rat. Neurotoxicology 1996, 18:425-441.
    • (1996) Neurotoxicology , vol.18 , pp. 425-441
    • Kodavanti, P.1    Tilson, H.2
  • 28
    • 0032427819 scopus 로고    scopus 로고
    • Congener-specific distribution of polychlorinated biphenyls in brain regions, blood, liver, and fat of adult rats following repeated exposure to Aroclor 1254
    • Kodavanti P.R.S., et al. Congener-specific distribution of polychlorinated biphenyls in brain regions, blood, liver, and fat of adult rats following repeated exposure to Aroclor 1254. Toxicol. Appl. Pharmacol. 1998, 153:199-210.
    • (1998) Toxicol. Appl. Pharmacol. , vol.153 , pp. 199-210
    • Kodavanti, P.R.S.1
  • 30
    • 36048955045 scopus 로고    scopus 로고
    • The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation
    • Liu S., et al. The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation. J. Clin. Invest. 2007, 117:3296-3305.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3296-3305
    • Liu, S.1
  • 31
    • 0036220774 scopus 로고    scopus 로고
    • Uterine muscle as a potential target of polychlorinated biphenyls during pregnancy
    • Loch-Caruso R. Uterine muscle as a potential target of polychlorinated biphenyls during pregnancy. Int. J. Hyg. Environ. Health 2002, 205:121-130.
    • (2002) Int. J. Hyg. Environ. Health , vol.205 , pp. 121-130
    • Loch-Caruso, R.1
  • 33
    • 33745070808 scopus 로고    scopus 로고
    • Influence of polychlorinated biphenyls on LH-stimulated secretion of progestereone and oxytocin from bovine luteal cells
    • Młynarczuk J., Kotwica J. Influence of polychlorinated biphenyls on LH-stimulated secretion of progestereone and oxytocin from bovine luteal cells. Pol. J. Vet. Sci. 2006, 9:101.
    • (2006) Pol. J. Vet. Sci. , vol.9 , pp. 101
    • Młynarczuk, J.1    Kotwica, J.2
  • 34
    • 33750133047 scopus 로고    scopus 로고
    • Regulation of iron metabolism by hepcidin
    • Nemeth E., Ganz T. Regulation of iron metabolism by hepcidin. Annu. Rev. Nutr. 2006, 26:323-342.
    • (2006) Annu. Rev. Nutr. , vol.26 , pp. 323-342
    • Nemeth, E.1    Ganz, T.2
  • 35
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E., et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J. Clin. Invest. 2004, 113:1271-1276.
    • (2004) J. Clin. Invest. , vol.113 , pp. 1271-1276
    • Nemeth, E.1
  • 36
    • 0035902605 scopus 로고    scopus 로고
    • Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
    • Nicolas G., et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Sci. Signal. 2001, 98:8780.
    • (2001) Sci. Signal. , vol.98 , pp. 8780
    • Nicolas, G.1
  • 37
    • 33845245942 scopus 로고    scopus 로고
    • Suppression of hepcidin during anemia requires erythropoietic activity
    • Pak M., Lopez M.A., Gabayan V., Ganz T., Rivera S. Suppression of hepcidin during anemia requires erythropoietic activity. Blood 2006, 108:3730-3735.
    • (2006) Blood , vol.108 , pp. 3730-3735
    • Pak, M.1    Lopez, M.A.2    Gabayan, V.3    Ganz, T.4    Rivera, S.5
  • 38
    • 77950617863 scopus 로고    scopus 로고
    • Efficacy of deferasirox in reducing and preventing cardiac iron overload in β-thalassemia
    • Pennell D.J., et al. Efficacy of deferasirox in reducing and preventing cardiac iron overload in β-thalassemia. Blood 2010, 115:2364-2371.
    • (2010) Blood , vol.115 , pp. 2364-2371
    • Pennell, D.J.1
  • 39
    • 78649634981 scopus 로고    scopus 로고
    • Hepcidin in human iron disorders: therapeutic implications
    • Pietrangelo A. Hepcidin in human iron disorders: therapeutic implications. J. Hepatol. 2011, 54:173.
    • (2011) J. Hepatol. , vol.54 , pp. 173
    • Pietrangelo, A.1
  • 42
    • 0038076142 scopus 로고    scopus 로고
    • Serum levels of 2, 2', 4, 4', 5, 5'-hexachlorobiphenyl (CB-153) in relation to markers of reproductive function in young males from the general Swedish population
    • Richthoff J., et al. Serum levels of 2, 2', 4, 4', 5, 5'-hexachlorobiphenyl (CB-153) in relation to markers of reproductive function in young males from the general Swedish population. Environ. Heal. Perspect. 2003, 111:409.
    • (2003) Environ. Heal. Perspect. , vol.111 , pp. 409
    • Richthoff, J.1
  • 43
    • 0028235721 scopus 로고
    • Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment
    • Safe S.H. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol. 1994, 24:87-149.
    • (1994) Crit. Rev. Toxicol. , vol.24 , pp. 87-149
    • Safe, S.H.1
  • 44
    • 0037352430 scopus 로고    scopus 로고
    • Effects of PCB exposure on neuropsychological function in children
    • Schantz S.L., Widholm J.J., Rice D.C. Effects of PCB exposure on neuropsychological function in children. Environ. Health Perspect. 2003, 111:357-576.
    • (2003) Environ. Health Perspect. , vol.111 , pp. 357-576
    • Schantz, S.L.1    Widholm, J.J.2    Rice, D.C.3
  • 47
    • 0035050749 scopus 로고    scopus 로고
    • Pesticides and breast cancer risk: a review of DDT, DDE, and dieldrin
    • Snedeker S.M. Pesticides and breast cancer risk: a review of DDT, DDE, and dieldrin. Environ. Heal. Perspect. 2001, 109:35.
    • (2001) Environ. Heal. Perspect. , vol.109 , pp. 35
    • Snedeker, S.M.1
  • 48
    • 79952227712 scopus 로고    scopus 로고
    • Ironing out cancer
    • Torti S.V., Torti F.M. Ironing out cancer. Cancer Res. 2011, 71:1511-1514.
    • (2011) Cancer Res. , vol.71 , pp. 1511-1514
    • Torti, S.V.1    Torti, F.M.2
  • 49
    • 0029555834 scopus 로고
    • Immunotoxicity of PCBs (aroclors) in relation to Great Lakes
    • Tryphonas H. Immunotoxicity of PCBs (aroclors) in relation to Great Lakes. Environ. Heal. Perspect. 1995, 103:35.
    • (1995) Environ. Heal. Perspect. , vol.103 , pp. 35
    • Tryphonas, H.1
  • 51
    • 0034901474 scopus 로고    scopus 로고
    • Organochlorines and breast cancer risk by receptor status, tumor size, and grade (Canada)
    • Woolcott C.G., et al. Organochlorines and breast cancer risk by receptor status, tumor size, and grade (Canada). Cancer Causes Control 2001, 12:395-404.
    • (2001) Cancer Causes Control , vol.12 , pp. 395-404
    • Woolcott, C.G.1
  • 52
    • 84862736353 scopus 로고    scopus 로고
    • 17β-Estradiol inhibits iron hormone hepcidin through an estrogen responsive element half-site
    • Yang Q., Jian J., Katz S., Abramson S.B., Huang X. 17β-Estradiol inhibits iron hormone hepcidin through an estrogen responsive element half-site. Endocrinology 2012, 153:3170-3178.
    • (2012) Endocrinology , vol.153 , pp. 3170-3178
    • Yang, Q.1    Jian, J.2    Katz, S.3    Abramson, S.B.4    Huang, X.5
  • 53
    • 0018805881 scopus 로고
    • Possible correlation between induction modes of hepatic enzymes by PCBs and their toxicity in rats
    • Yoshimura H., Yoshihara S.i., Ozawa N., Miki M. Possible correlation between induction modes of hepatic enzymes by PCBs and their toxicity in rats. Ann. N. Y. Acad. Sci. 1979, 320:179-192.
    • (1979) Ann. N. Y. Acad. Sci. , vol.320 , pp. 179-192
    • Yoshimura, H.1    Yoshihara, S.2    Ozawa, N.3    Miki, M.4
  • 54
    • 0034234063 scopus 로고    scopus 로고
    • Breast cancer risk associated with congeners of polychlorinated biphenyls
    • Zheng T., et al. Breast cancer risk associated with congeners of polychlorinated biphenyls. Am. J. Epidemiol. 2000, 152:50-58.
    • (2000) Am. J. Epidemiol. , vol.152 , pp. 50-58
    • Zheng, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.