A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation

eLife

Volumn 2013, Issue 2, 2013, Pages

  Bleichert, Franziska ^a,d   Balasov, Maxim ^b   Chesnokov, Igor ^b   Nogales, Eva ^a,c   Botchan, Michael R ^a   Berger, James M ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 5; MINICHROMOSOME MAINTENANCE PROTEIN 6; MINICHROMOSOME MAINTENANCE PROTEIN 7; ORC6 PROTEIN, HUMAN; ORIGIN RECOGNITION COMPLEX; ORIGIN RECOGNITION COMPLEX 1; ORIGIN RECOGNITION COMPLEX 3; ORIGIN RECOGNITION COMPLEX 6; RECOMBINANT PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL CELL; ANISOTROPY; ARTICLE; CHROMATIN; CONGENITAL MALFORMATION; CONTROLLED STUDY; CYTOARCHITECTURE; DROSOPHILA; DWARFISM; ELECTRON MICROSCOPY; GEL FILTRATION CHROMATOGRAPHY; GENE MUTATION; GENETICS; GROWTH DISORDER; HUMAN; IMAGE PROCESSING; IMMUNOPRECIPITATION; MEIER-GORLIN SYNDROME; MICROGNATHIA; MICROTIA; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY; PATELLA; PROTEIN PURIFICATION; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; ULTRASTRUCTURE; WESTERN BLOTTING;

ABNORMALITIES; ANIMALS; CONGENITAL MICROTIA; DROSOPHILA; GENETICS; GROWTH DISORDERS; HUMANS; MICROGNATHISM; MICROSCOPY, ELECTRON; MUTATION; ORIGIN RECOGNITION COMPLEX; PATELLA; ULTRASTRUCTURE;

EUKARYOTA; METAZOA; SACCHAROMYCETALES;

EID: 84885347124     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.00882.001     Document Type: Article

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