Oxidative stress enhances Axl-mediated cell migration through an Akt1/Rac1-dependent mechanism

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 1246-1256

  Huang, Jhy Shrian ^a,b   Cho, Chun Yu ^a   Hong, Chih Chen ^a   Yan, Ming De ^a   Hsieh, Mao Chih ^b   Lay, Jong Ding ^c   Lai, Gi Ming ^a,b,d   Cheng, Ann Lii ^a,e   Chuang, Shuang En ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c National Taichung Nursing College   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Akt1; Axl; Free radicals; NSCLC; Oxidative stress; Rac1; ROS

Indexed keywords

AXL PROTEIN; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR GROWTH;

2′,7′-DICHLORODIHYDROFLUORESCEIN DIACETATE; AKT1; AXL; DCF-DA; FREE RADICALS; GAS6; GROWTH-ARREST-SPECIFIC 6; NON-SMALL-CELL LUNG CANCER; NSCLC; OXIDATIVE STRESS; RAC1; REACTIVE OXYGEN SPECIES; RECEPTOR TYROSINE KINASE; ROS; RTK; SOD; SUPEROXIDE DISMUTASE;

ADENOCARCINOMA; CELL LINE, TUMOR; CELL MOVEMENT; CELL TRANSFORMATION, NEOPLASTIC; ENZYME ACTIVATION; HUMANS; HYDROGEN PEROXIDE; LUNG NEOPLASMS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RAC1 GTP-BINDING PROTEIN; RECEPTOR PROTEIN-TYROSINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84885340255     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.09.011     Document Type: Article

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