The cysteine dioxgenase knockout mouse: Altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS- production and evidence of pancreatic and lung toxicity

Antioxidants and Redox Signaling

Volumn 19, Issue 12, 2013, Pages 1321-1336

  Roman, Heather B ^a   Hirschberger, Lawrence L ^a   Krijt, Jakub ^b   Valli, Alessandro ^a   Kožich, Viktor ^b   Stipanuk, Martha H ^a  

^a Department of Obstetrics Gynecology   (United States)

^b Charles University in Prague and General University Hospital in Prague   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

BASE; CYSTATHIONINE; CYSTATHIONINE BETA SYNTHASE; CYSTEINE; CYSTEINE DIOXGENASE; CYTOCHROME C OXIDASE; DIOXYGENASE; GLUTATHIONE; HOMOCYSTEINE; HYDROGEN SULFIDE; HYPOTAURINE; LANTHIONINE; METHIONINE; SERINE; SULFATE; SULFIDE; TAURINE; THIOSULFATE; UNCLASSIFIED DRUG;

AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BODY WEIGHT; CONTROLLED STUDY; CYSTEINE METABOLISM; DESULFHYDRATION; DISEASE PREDISPOSITION; ENZYME INHIBITION; ENZYME STABILITY; EXPERIMENTAL MODEL; FEMALE; FOOD INTAKE; HYDRATION; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LIVER TOXICITY; LUNG TOXICITY; MALE; MOUSE; NEPHROTOXICITY; NEWBORN; NONHUMAN; OXIDATION; PANCREAS DISEASE; PANCREAS FUNCTION; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TISSUE LEVEL; URINARY EXCRETION; WILD TYPE;

ALANINE; ANIMALS; CYSTATHIONINE; CYSTEINE; CYSTEINE DIOXYGENASE; DIET; ELECTRON TRANSPORT COMPLEX IV; ENZYME STABILITY; FEMALE; GLUTATHIONE; HYDROGEN SULFIDE; KIDNEY; LIVER; LUNG; MALE; MICE; MICE, KNOCKOUT; ORGAN SPECIFICITY; PANCREAS; SULFIDES; TAURINE;

EID: 84885231249     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.5010     Document Type: Article

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