Generation of human-induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro

Journal of Molecular Neuroscience

Volumn 51, Issue 2, 2013, Pages 237-248

  Xia, Guangbin ^a   Santostefano, Katherine ^a   Hamazaki, Takashi ^a   Liu, Jilin ^a   Subramony, S H ^a   Terada, Naohiro ^a   Ashizawa, Tetsuo ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Ataxin; Induced pluripotent stem cells; Polyglutamine; Spinocerebellar ataxia

Indexed keywords

ATAXIN 2; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; NUCLEIC ACID BINDING PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CAG REPEAT; CONTROLLED STUDY; EMBRYONIC STEM CELL; EXPLANT; FEEDER CELL; GENE INDUCTION; GERM LAYER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; KARYOTYPE; MALE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEUROPATHOLOGY; PATHOGENESIS; PLURIPOTENT STEM CELL; PRIMARY CULTURE; RETROVIRUS INFECTION; ROSETTE FORMATION; SKIN BIOPSY; SKIN FIBROBLAST; SPINOCEREBELLAR ATAXIA TYPE 2; SPINOCEREBELLAR DEGENERATION; STEM CELL CULTURE;

IPS;

ADULT; CELL LINE, TRANSFORMED; CELLS, CULTURED; FIBROBLASTS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NUCLEAR REPROGRAMMING; OCTAMER TRANSCRIPTION FACTOR-3; PROTO-ONCOGENE PROTEINS C-MYC; SOXB1 TRANSCRIPTION FACTORS; SPINOCEREBELLAR ATAXIAS; TRANSFECTION;

EID: 84885184433     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9930-2     Document Type: Article

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