L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner

Neurobiology of Aging

Volumn 35, Issue 1, 2014, Pages 88-95

  Wang, Yue ^a   Mattson, Mark P ^a,b  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3xTgAD mice; Aging; CA1; L type Ca2+ currents

Indexed keywords

4 AMINOPYRIDINE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMYLOID BETA PROTEIN; CALCIUM CHANNEL L TYPE; N METHYL DEXTRO ASPARTIC ACID; TAU PROTEIN; N METHYLASPARTIC ACID; VOLTAGE GATED POTASSIUM CHANNEL;

3XTG MOUSE; AGE; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CALCIUM CURRENT; CELL DENSITY; CELLULAR DISTRIBUTION; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE NUCLEUS; ENZYME PHOSPHORYLATION; GRANULE CELL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; MOUSE; NERVE CELL DEGENERATION; NERVE CELL NETWORK; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SYNAPSE; WHOLE CELL; AGING; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DENTATE GYRUS; GENETICS; METABOLISM; PATCH CLAMP TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES; TRANSGENIC MOUSE; 3XTGAD MICE; CA1; L-TYPE CA(2+) CURRENTS; METHODOLOGY;

AGING; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CA1 REGION, HIPPOCAMPAL; CA3 REGION, HIPPOCAMPAL; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; COGNITION DISORDERS; DENTATE GYRUS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; N-METHYLASPARTATE; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; POTASSIUM CHANNELS, VOLTAGE-GATED; SYNAPSES; TAU PROTEINS;

3XTGAD MICE; AGING; CA1; L-TYPE CA(2+) CURRENTS;

EID: 84885182150     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.07.007     Document Type: Article

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