Age-related working memory impairment is correlated with increases in the L-type calcium channel protein α1D (Cav1.3) in area CA1 of the hippocampus and both are ameliorated by chronic nimodipine treatment

Molecular Brain Research

Volumn 110, Issue 2, 2003, Pages 193-202

  Veng, Lone M ^a,c   Mesches, Michael H ^a,b   Browning, Michael D ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c H LUNDBECK A S   (Denmark)

Author keywords

Aging; Cav1.3; Hippocampus; L type calcium channel; Learning; Nimodipine

Indexed keywords

CALCIUM CHANNEL L TYPE; L TYPE CALCIUM CHANNEL PROTEIN ALPHA 1D; MEMBRANE PROTEIN; NIMODIPINE; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AGED; AGING; ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; GROUPS BY AGE; HIPPOCAMPUS; MAZE TEST; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TASK PERFORMANCE; WESTERN BLOTTING; WORKING MEMORY;

AGING; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; HIPPOCAMPUS; MAZE LEARNING; MEMORY DISORDERS; NEURONS; NIMODIPINE; RATS; RATS, INBRED F344; REACTION TIME; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNAPTIC TRANSMISSION;

RODENTIA;

EID: 0347912964     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00643-5     Document Type: Article

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