Neuroprotective effects of paeoniflorin, but not the isomer albiflorin, are associated with the suppression of intracellular calcium and calcium/calmodulin protein kinase II in PC12 cells

Journal of Molecular Neuroscience

Volumn 51, Issue 2, 2013, Pages 581-590

  Wang, Di ^a   Tan, Qing Rong ^b   Zhang, Zhang Jin ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

AKT; Albiflorin; Apoptosis; CaMKII; Glutamate; Paeoniflorin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALBIFLORIN; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GLUTAMIC ACID; GLYCOGEN SYNTHASE KINASE 3BETA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PAEONIFLORIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; BRAIN LEVEL; CALCIUM CELL LEVEL; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PC12 CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

PAEONIA; PAEONIA LACTIFLORA; RANUNCULACEAE;

ANIMALS; APOPTOSIS; BENZOATES; BRIDGED COMPOUNDS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL SURVIVAL; CYTOPLASM; GLUCOSIDES; GLUTAMIC ACID; NEUROPROTECTIVE AGENTS; PC12 CELLS; PROTEIN KINASE INHIBITORS; RATS; REACTIVE OXYGEN SPECIES;

EID: 84885179749     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0031-7     Document Type: Article

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