Age-related expression of calcium/calmodulin-dependent protein kinase II A in the hippocampus and cerebral cortex of senescence accelerated mouse prone/8 mice is modulated by anti-Alzheimer's disease drugs

Neuroscience

Volumn 159, Issue 1, 2009, Pages 308-315

  Zhang, G R ^a   Cheng, X R ^a   Zhou, W X ^a   Zhang, Y X ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Alzheimer's disease; anti AD drugs; calcium calmodulin dependent protein kinase II ; senescence accelerated mouse

Indexed keywords

ALISMA PLANTAGO AQUATICA EXTRACT; ANGELICA SINENSIS EXTRACT; ATRACTYLODES MACROCEPHALA EXTRACT; BA WEI DI HUANG EXTRACT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; COPTIS RHIZOME EXTRACT; CORNUS OFFICINALIS EXTRACT; CORTEX CINNAMONI EXTRACT; DANG GUI SHAO YAO SAN EXTRACT; DIOSCOREAE OPPOSITE EXTRACT; FRUCTUS CORNI EXTRACT; GARDENIAE FRUCTUS EXTRACT; HUANG LIAN JIE DU EXTRACT; HUPERZINE A; LIGUSTICUM CHUANXIONG EXTRACT; LIU WEI DI HUANG EXTRACT; PAEONIA LACTIFLORA EXTRACT; PAEONIA SUFFRYTICOSA EXTRACT; PHELLODENDRI CORTEX EXTRACT; PLANT EXTRACT; PORIA COCOS EXTRACT; PORIA TENUIFOLIA EXTRACT; PORIE COCOS EXTRACT; RADIX ACONITE LATERALIS PREPARATA EXTRACT; RADIX REHMANNIA EXTRACT; REHMANNIA GLUTINOSA EXTRACT; RHIZOMA DIOSCOREAE EXTRACT; SCUTELLARIAE RADIX; TIAO XIN FANG EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AGING; ALISMA ORIENTALE; ALISMA PLANTAGO AQUATICA; ALZHEIMER DISEASE; ANGELICA SINENSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BA WEI DI HUANG; BRAIN CORTEX; CHINESE MEDICINE; CONTROLLED STUDY; COPTIS; CORNUS; CORTEX CINNAMONI; CORTEX MOUTAN RADICIS; DANG GUI SHAO YAO SAN; DIOSCOREAE OPPOSITE; DOWN REGULATION; DRUG TARGETING; FRUCTUS CORNI; FRUCTUS GARDENIAE; GENE EXPRESSION; HIPPOCAMPUS; HUANG LIAN JIE DU; LIGUSTICUM CHUANXIONG; LIU WEI DI HUANG; MALE; MEDICINAL PLANT; MENTAL DETERIORATION; MOUSE; NEUROMODULATION; NONHUMAN; PAEONIA SUFFRYTICOSA; PHARMACOGNOSY; PHELLODENDRI CORTEX; PORIA COCOS; PORIA TENUIFOLIA; PORIE COCOS; PRIORITY JOURNAL; RADIX ACONITE LATERALIS PREPARATA; RADIX REHMANNIA; REAL TIME POLYMERASE CHAIN REACTION; REHMANNIA; RHIZOMA ALISMATIS; RHIZOMA DIOSCOREAE; SCUTELLARIA; SENESCENCE; SENESCENCE ACCELERATED MOUSE; TIAO XIN FANG; WESTERN BLOTTING;

AGING; ANALYSIS OF VARIANCE; ANIMALS; ANTIPSYCHOTIC AGENTS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CEREBRAL CORTEX; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MICE; MICE, MUTANT STRAINS; RNA, MESSENGER;

EID: 60349108170     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.06.068     Document Type: Article

References (49)

1. Ahmed T., and Frey J.U. Plasticity-specific phosphorylation of CaMKII, MAP-kinases and CREB during late-LTP in rat hippocampal slices in vitro. Neuropharmacology 49 4 (2005) 477-492
2. Bass M.A., Jiao Y., MacMillan L.B., Carmody L.C., Bartlett R.K., and Colbran R.J. Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2. J Biol Chem 280 42 (2005) 35329-35336
3. 2+/calmodulin-dependent protein kinase 2 activity in hippocampus. J Biol Chem 272 39 (1997) 24133-24136
4. Butterfield D.A., and Poon H.F. The senescence-accelerated prone mouse (SAMP8): a model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease. Exp Gerontol 40 (2005) 774-783
5. Canudas A.M., Gutierrez-Cuesta J., Rodríguez M.I., Acuña-Castroviejo D., Sureda F.X., Camins A., and Pallàs M. Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM). Mech Ageing Dev 126 12 (2005) 1300-1304
6. Chen G.H., Wang Y.J., Wang X.M., and Zhou J.N. Accelerated senescence prone mouse-8 shows early onset of deficits in spatial learning and memory in the radial six-arm water maze. Physiol Behav 82 (2004) 883-890
7. Cheng X.R., Zhou W.X., Zhang Y.X., Zhou D.S., Yang R.F., and Chen L.F. Differential gene expression profiles in the hippocampus of senescence-accelerated mouse. Neurobiol Aging 28 (2007) 497-506
8. Cui Y., Hou S.L., Yan Z.H., and Chang Z.F. Effect of shu di-huang on the expression of c-fos and NGF in hippocampi and learning and memory of rats damaged thalamic arcuate nucleus. Zhongguo Zhong Yao Za Zhi 28 4 (2003) 362-365
9. Cui Y., Yan Z.H., Hou S.L., and Chang Z.F. Effect of shu di-huang on the transmitter and receptor of amino acid in brain and learning and memory of dementia model. Zhongguo Zhong Yao Za Zhi 28 9 (2003) 862-866
10. Fang Q., Zhan X.P., Mo J.L., and Sun M. The effect of huanglian jiedu tang on Alzheimer's disease and its influence on cytokines. Zhongguo Zhong Yao Za Zhi 29 6 (2004) 575-578
11. 2+/calmodulin-dependent protein kinase II. Proc Natl Acad Sci U S A 85 (1988) 6218-6221
12. Giese K.P., Fedorov N.B., Filipkowski R.K., and Silva A.J. Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning. Science 279 5352 (1998) 870-873
13. Howes M.J., and Houghton P.J. Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function. Pharmacol Biochem Behav 75 3 (2003) 513-527
14. Hsieh M.T., Cheng S.J., Lin L.W., Wang W.H., and Wu C.R. The ameliorating effects of acute and chronic administration of liu wei dihuang wang on learning performance in rodents. Biol Pharm Bull 26 2 (2003) 156-161
15. Hwang Y.S., Shin C.Y., Huh Y., and Ryu J.H. Hwangryun-hae-dok-tang (huanglian-jie-du-tang) extract and its constituents reduce ischemia-reperfusion brain injury and neutrophil infiltration in rats. Life Sci 71 18 (2002) 2105-2117
16. Kou J., Zhu D., and Yan Y. Neuroprotective effects of the aqueous extract of the Chinese medicine danggui-shaoyao-san on aged mice. J Ethnopharmacol 97 2 (2005) 313-318
17. Kumar V.B., Farr S.A., Flood J.F., Kamlesh V., Franko M., Banks W.A., and Morley J.E. Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice. Peptides 21 (2000) 1769-1775
18. Li R., Qin L., and Wang Y. Experimental study on preventive effect of traditional Chinese medicine replenishing recipe on acute oxygen toxicity caused by hyperbaric oxygen. Zhongguo Zhong Xi Yi Jie He Za Zhi 18 10 (1998) 623-625
19. Lin K.F., Chang R.C., Suen K.C., So K.F., and Hugon J. Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity. Eur J Neurosci 2004 19 8 (2004) 2047-2055
20. Lin S.M., Wang J., and Zhou R.Q. Clinical study on treatment of Alzheimer's disease from the viewpoint of Xin and Shen. Zhongguo Zhong Xi Yi Jie He Za Zhi 23 8 (2003) 583-586
21. Lu M.C. Danggui shaoyao san improve colchichine-induced learning acquisition impairment in rats. Acta Pharmacol Sin 22 12 (2001) 1149-1153
22. Mckee A.C., Kosik K.S., Kennedy M.B., and Kowall N.W. Hippocampal neurons predisposed to neurofibrillary tangle formation are enriched in type II calcium/calmodulin-dependent protein kinase. J Neuropathol Exp Neurol 49 (1990) 49-63
23. Morley J.E., Kumar V.B., Bernardo A.E., Farr S.A., Uezu K., Tumosa N., and Flood J.F. Beta-amyloid precursor polypeptide in SAMP8 mice affects learning and memory. Peptides 21 (2000) 1761-1767
24. Murray K.D., Gall C.M., Jones E.G., and Isackson P.J. Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease. Neuroscience 60 1 (1994) 37-48
25. Nishikawa T., Takahashi J.A., Fujibayashi Y., Fujisawa H., Zhu B., Nishimura Y., Ohnishi K., Higuchi K., Hashimoto N., and Hosokawa M. An early stage mechanism of the age-associated mitochondrial dysfunction in the brain of SAMP8 mice: an age-associated neurodegeneration animal model. Neurosci Lett 254 (1998) 69-72
26. Nomura Y., and Okuma Y. Age-related defects in lifespan and learning ability in SAMP8 mice. Neurobiol Aging 20 (1999) 111-115
27. Ohta A., Akiguchi I., Seriu N., Ohnishi K., Yagi H., Higuchi K., and Hosokawa M. Deterioration in learning and memory of fear conditioning in response to context in aged SAMP8 mice. Neurobiol Aging 22 (2001) 479-484
28. Ohta A., Akiguchi I., Seriu N., Ohnishi K., Yagi H., Higuchi K., and Hosokawa M. Deterioration in learning and memory of inferential tasks for evaluation of transitivity and symmetry in aged SAMP8 mice. Hippocampus 12 (2002) 803-810
29. Ohta A., Hirano T., Yagi H., Tanaka S., Hosokawa M., and Takeda T. Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task. Brain Res 498 (1989) 195-198
30. Omkumar R.V., Kiely M.J., Rosenstein A.J., Min K.T., and Kennedy M.B. Identification of a phosphorylation site for calcium/calmodulin dependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptor. J Biol Chem 271 49 (1996) 31670-31678
31. Poon H.F., Castegna A., Farr S.A., Thongboonkerd V., Lynn B.C., Banks W.A., Morley J.E., Klein J.B., and Butterfield D.A. Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain. Neuroscience 26 (2004) 915-926
32. Poon H.F., Farr S.A., Thongboonkerd V., Lynn B.C., Banks W.A., Morley J.E., Klein J.B., and Butterfield D.A. Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders. Neurochem Int 46 (2005) 159-168
33. Qiao H.F., Yang S., and Zhou W.X. Inhibitory effect of active fraction of tiaoxin recipe on beta-amyloid protein induced long-term potentiation in CA1 area of rats' hippocampal slices. Zhongguo Zhong Xi Yi Jie He Za Zhi 25 5 (2005) 429-431
34. Qiao H.F., Yang S., Zhou W.X., and Zhang Y.X. NT-1, an active constituent extracted from tiaoxin recipe, enhances long-term potentiation of CA1 subfield in rat hippocampal slices. Life Sci 79 1 (2006) 8-15
35. Reynolds C.H., Betts J.C., Blackstock W.P., Nebreda A.R., and Anderton B.H. Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta. J Neurochem 74 4 (2000) 1587-1595
36. 2+/calmodulin-dependent protein kinase kinases in the adult rat brain. Eur J Neurosci 12 1 (2000) 89-99
37. Silva A.J., Paylor R., Wehner J.M., and Tonegawa S. Impaired spatial learning in a-calcium-calmodulin kinaseII mutant mice. Science 257 (1992) 206-211
38. Silva A.J., Stevens C.F., Tonegawa S., and Wang Y. Deficient hippocampal long-term potentiation in a-calcium-calmodulin kinase II mutant mice. Science 257 (1992) 201-206
39. Simonian N.A., Elvhage T., Czernik A.J., Greengard P., and Hyman B.T. Calcium/calmodulin-dependent protein kinase II immunostaining is preserved in Alzheimer's disease hippocampal neurons. Brain Res 657 (1994) 294-299
40. Strain J.F., and Morley J.E. Age related impairment of aversive and appetitive learning in the SAMP P/8 mouse strain. A model of dementia of early onset. J Gerontol Biol Sci 47 (1992) B52-B59
41. Takahashi R., and Goto S. Altered gene expression in the brain of senescence accelerated mouse SAMP8. Int Congr Ser 1260 (2004) 85-90
42. Wang Q., and Wang J. Injection of bradykinin or cyclosporine A to hippocampus induces Alzheimer-like phosphorylation of tau and abnormal behavior in rats. Chin Med J (Engl) 115 6 (2002) 884-887
43. Wang Y.J., Chen G.H., Hu X.Y., Lu Y.P., Zhou J.N., and Liu R.Y. The expression of calcium/calmodulin-dependent protein kinase II-alpha in the hippocampus of patients with Alzheimer's disease and its links with AD-related pathology. Brain Res 1031 1 (2005) 101-108
44. Wei X.L., Zhang Y.X., and Zhou J.H. Alzheimer's disease-related gene expression in the brain of senescence accelerated mouse. Neurosci Lett 268 (1999) 139-142
45. Yagi H., Katoh S., Akiguchi I., and Takeda T. Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-p/8 as an animal model of disturbance in recent memory. Brain Res 474 (1988) 86-93
46. Yang G., Lin S.M., and Zhao W.K. Effect of TX0201 on expression of the apoptosis signal transduction molecule caspase-3 and apoptosis associated genes bcl-2 and bax mRNA in brain tissue of rat analogue model of Alzheimer's disease. Zhongguo Zhong Xi Yi Jie He Za Zhi 26 2 (2006) 147-151
47. Yuan Z.Z., Zhu L.Q., Pang H., Shan Z.S., Wang S.R., Gao Y.H., and Niu F.L. Protective action of effective components of Huanglian Jiedu decoction on hypoxia and reoxygenation injury in cultured rat cerebral microvascular endothelial cells. Zhongguo Zhong Yao Za Zhi 32 3 (2007) 249-252
48. Zhang H.Y., Liang Y.Q., Tang X.C., He X.C., and Bai D.L. Stereoselectivities of enantiomers of huperzine A in protection against beta-amyloid(2535)-induced injury in PC12 and NG108-15 cells and cholinesterase inhibition in mice. Neurosci Lett 317 (2002) 143-146
49. Zhu X.Z., Li X.Y., and Liu J. Recent pharmacological studies on natural products in China. Eur J Pharmacol 500 1-3 (2004) 221-230