5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 2, 2011, Pages 961-967

  Xie, Lijuan ^a,c   Cui, Jingnan ^b   Qian, Xuhong ^c   Xu, Yufang ^c   Liu, Jianwen ^c   Xu, Ruian ^a  

^a HUAQIAO UNIVERSITY   (China)

^b DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

5 Aromatic substituted naphthalimide; Amonafide; DNA binding; Suzuki reaction

Indexed keywords

5 (3' NITRO PHENYL) 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 (3',4' 2F PHENYL) 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 (4' 1F PHENYL) 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 (4' METHYL PHENYL) 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 (4' TRIFLUOMETHYL PHENYL) 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 BROMO 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 PHENYL 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 THIOPHENE 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; AMONAFIDE; ANTINEOPLASTIC AGENT; NAPHTHALIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

AMINATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BROMINATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; DRUG SYNTHESIS; FEMALE; HELA CELL; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CIRCULAR DICHROISM; DNA; HUMANS; INTERCALATING AGENTS; NAPHTHALIMIDES; SPECTROMETRY, FLUORESCENCE;

EID: 78651519408     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.11.055     Document Type: Article

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