The extended transmembrane orai1 N-terminal (ETON) region combines binding interface and gate for orai1 activation by STIM1

Journal of Biological Chemistry

Volumn 288, Issue 40, 2013, Pages 29025-29034

  Derler, Isabella ^a   Plenk, Peter ^a   Fahrner, Marc ^a   Muik, Martin ^a   Jardin, Isaac ^a   Schindl, Rainer ^a   Gruber, Hermann J ^a   Groschner, Klaus ^b   Romanin, Christoph ^a  

^a JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING INTERFACE; CYTOSOLIC; HOT SPOT; N-TERMINALS; PROTEIN-PROTEIN INTERACTIONS; THERAPEUTIC DRUGS; TRANSMEMBRANES;

BIOCHEMISTRY; BIOLOGY;

PROTEINS;

CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; STROMAL INTERACTION MOLECULE 1;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CALCIUM TRANSPORT; CELL MEMBRANE; CHANNEL GATING; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROPHOBICITY; MEMBRANE DAMAGE; MUTAGENESIS; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

CALCIUM CHANNELS; CALCIUM INTRACELLULAR RELEASE; CALCIUM SIGNALING; ELECTROPHYSIOLOGY; ION CHANNELS;

ACTION POTENTIALS; AMINO ACID SEQUENCE; AMINO ACIDS; BINDING SITES; CALCIUM CHANNELS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ION CHANNEL GATING; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; NEOPLASM PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84885160599     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.501510     Document Type: Article

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