-
1
-
-
0032199006
-
Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
-
Colquhoun D (1998). Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 125, 924-947.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 924-947
-
-
Colquhoun, D.1
-
3
-
-
70349116421
-
2+ entry in the immune system and beyond
-
2+ entry in the immune system and beyond. Immunol Rev 231, 189-209.
-
(2009)
Immunol Rev
, vol.231
, pp. 189-209
-
-
Feske, S.1
-
4
-
-
77955566489
-
CRAC channelopathies
-
Feske S (2010). CRAC channelopathies. Pflugers Arch 460, 417-435.
-
(2010)
Pflugers Arch
, vol.460
, pp. 417-435
-
-
Feske, S.1
-
5
-
-
77950377028
-
Molecular basis of calcium signalling in lymphocytes: STIM and ORAI
-
Hogan PG, Lewis RS & Rao A (2010). Molecular basis of calcium signalling in lymphocytes: STIM and ORAI. Annu Rev Immunol 28, 491-533.
-
(2010)
Annu Rev Immunol
, vol.28
, pp. 491-533
-
-
Hogan, P.G.1
Lewis, R.S.2
Rao, A.3
-
6
-
-
80051959475
-
2+ (CRAC) channels by stromal interaction molecule 1 (STIM1)
-
2+ (CRAC) channels by stromal interaction molecule 1 (STIM1). Proc Natl Acad Sci U S A 108, 13299-13304.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 13299-13304
-
-
Hoover, P.J.1
Lewis, R.S.2
-
7
-
-
84870655957
-
Crystal structure of the calcium release-activated calcium channel Orai
-
Hou X, Pedi L, Diver MM & Long SB (2012). Crystal structure of the calcium release-activated calcium channel Orai. Science 338, 1308-1313.
-
(2012)
Science
, vol.338
, pp. 1308-1313
-
-
Hou, X.1
Pedi, L.2
Diver, M.M.3
Long, S.B.4
-
8
-
-
67349237167
-
A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels
-
Kawasaki T, Lange I & Feske S (2009). A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels. Biochem Biophys Res Commun 385, 49-54.
-
(2009)
Biochem Biophys Res Commun
, vol.385
, pp. 49-54
-
-
Kawasaki, T.1
Lange, I.2
Feske, S.3
-
9
-
-
84859618951
-
Store-operated calcium channels: New perspectives on mechanism and function
-
pii: a003970
-
Lewis RS (2011). Store-operated calcium channels: New perspectives on mechanism and function. Cold Spring Harb Perspect Biol 3, pii: a003970.
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
-
-
Lewis, R.S.1
-
10
-
-
79651469360
-
Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits
-
Li Z, Liu L, Deng Y, Ji W, Du W, Xu P, Chen L & Xu T (2010). Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits. Cell Res 21, 305-315.
-
(2010)
Cell Res
, vol.21
, pp. 305-315
-
-
Li, Z.1
Liu, L.2
Deng, Y.3
Ji, W.4
Du, W.5
Xu, P.6
Chen, L.7
Xu, T.8
-
12
-
-
78650070349
-
A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating
-
Lis A, Zierler S, Peinelt C, Fleig A & Penner R (2010). A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. J Gen Physiol 136, 673-686.
-
(2010)
J Gen Physiol
, vol.136
, pp. 673-686
-
-
Lis, A.1
Zierler, S.2
Peinelt, C.3
Fleig, A.4
Penner, R.5
-
13
-
-
33748548406
-
2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions
-
2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. J Cell Biol 174, 815-825.
-
(2006)
J Cell Biol
, vol.174
, pp. 815-825
-
-
Luik, R.M.1
Wu, M.M.2
Buchanan, J.3
Lewis, R.S.4
-
14
-
-
0030960276
-
Predicting coiled-coil regions in proteins
-
Lupas A (1997). Predicting coiled-coil regions in proteins. Curr Opin Struct Biol 7, 388-393.
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 388-393
-
-
Lupas, A.1
-
15
-
-
78650643147
-
T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells
-
Ma J, McCarl CA, Khalil S, Luthy K & Feske S (2010). T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells. Eur J Immunol 40, 3028-3042.
-
(2010)
Eur J Immunol
, vol.40
, pp. 3028-3042
-
-
Ma, J.1
McCarl, C.A.2
Khalil, S.3
Luthy, K.4
Feske, S.5
-
16
-
-
78650653524
-
2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection
-
2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection. J Immunol 185, 5845-5858.
-
(2010)
J Immunol
, vol.185
, pp. 5845-5858
-
-
McCarl, C.A.1
Khalil, S.2
Ma, J.3
Oh-hora, M.4
Yamashita, M.5
Roether, J.6
Kawasaki, T.7
Jairaman, A.8
Sasaki, Y.9
Prakriya, M.10
Feske, S.11
-
18
-
-
79955628984
-
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation
-
Muik M, Fahrner M, Schindl R, Stathopulos P, Frischauf I, Derler I, Plenk P, Lackner B, Groschner K, Ikura M & Romanin C (2011). STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation. EMBO J 30, 1678-1689.
-
(2011)
EMBO J
, vol.30
, pp. 1678-1689
-
-
Muik, M.1
Fahrner, M.2
Schindl, R.3
Stathopulos, P.4
Frischauf, I.5
Derler, I.6
Plenk, P.7
Lackner, B.8
Groschner, K.9
Ikura, M.10
Romanin, C.11
-
19
-
-
43149090543
-
Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation
-
Muik M, Frischauf I, Derler I, Fahrner M, Bergsmann J, Eder P, Schindl R, Hesch C, Polzinger B, Fritsch R, Kahr H, Madl J, Gruber H, Groschner K & Romanin C (2008). Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. J Biol Chem 283, 8014-8022.
-
(2008)
J Biol Chem
, vol.283
, pp. 8014-8022
-
-
Muik, M.1
Frischauf, I.2
Derler, I.3
Fahrner, M.4
Bergsmann, J.5
Eder, P.6
Schindl, R.7
Hesch, C.8
Polzinger, B.9
Fritsch, R.10
Kahr, H.11
Madl, J.12
Gruber, H.13
Groschner, K.14
Romanin, C.15
-
21
-
-
56649094581
-
STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy
-
Navarro-Borelly L, Somasundaram A, Yamashita M, Ren D, Miller RJ & Prakriya M (2008). STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy. J Physiol 586, 5383-5401.
-
(2008)
J Physiol
, vol.586
, pp. 5383-5401
-
-
Navarro-Borelly, L.1
Somasundaram, A.2
Yamashita, M.3
Ren, D.4
Miller, R.J.5
Prakriya, M.6
-
22
-
-
77951879382
-
Store-operated CRAC channels: function in health and disease
-
Parekh AB (2010). Store-operated CRAC channels: function in health and disease. Nat Rev Drug Discov 9, 399-410.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 399-410
-
-
Parekh, A.B.1
-
23
-
-
61349137530
-
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
-
Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, Raunser S, Walz T, Garcia KC, Dolmetsch RE & Lewis RS (2009). STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 136, 876-890.
-
(2009)
Cell
, vol.136
, pp. 876-890
-
-
Park, C.Y.1
Hoover, P.J.2
Mullins, F.M.3
Bachhawat, P.4
Covington, E.D.5
Raunser, S.6
Walz, T.7
Garcia, K.C.8
Dolmetsch, R.E.9
Lewis, R.S.10
-
24
-
-
33748669602
-
Orai1 is an essential pore subunit of the CRAC channel
-
Prakriya M, Feske S, Gwack Y, Srikanth S, Rao A & Hogan PG (2006). Orai1 is an essential pore subunit of the CRAC channel. Nature 443, 230-233.
-
(2006)
Nature
, vol.443
, pp. 230-233
-
-
Prakriya, M.1
Feske, S.2
Gwack, Y.3
Srikanth, S.4
Rao, A.5
Hogan, P.G.6
-
25
-
-
79960759956
-
Calcium in tumour metastasis: new roles for known actors
-
Prevarskaya N, Skryma R & Shuba Y (2011). Calcium in tumour metastasis: new roles for known actors. Nat Rev Cancer 11, 609-618.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 609-618
-
-
Prevarskaya, N.1
Skryma, R.2
Shuba, Y.3
-
26
-
-
77949332488
-
Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation
-
Schuhmann MK, Stegner D, Berna-Erro A, Bittner S, Braun A, Kleinschnitz C, Stoll G, Wiendl H, Meuth SG & Nieswandt B (2010). Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation. J Immunol 184, 1536-1542.
-
(2010)
J Immunol
, vol.184
, pp. 1536-1542
-
-
Schuhmann, M.K.1
Stegner, D.2
Berna-Erro, A.3
Bittner, S.4
Braun, A.5
Kleinschnitz, C.6
Stoll, G.7
Wiendl, H.8
Meuth, S.G.9
Nieswandt, B.10
-
28
-
-
59449110657
-
Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics
-
Stathopulos PB, Zheng L & Ikura M (2009). Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics. J Biol Chem 284, 728-732.
-
(2009)
J Biol Chem
, vol.284
, pp. 728-732
-
-
Stathopulos, P.B.1
Zheng, L.2
Ikura, M.3
-
30
-
-
79953203530
-
Competitive modulation of CRAC channel gating by STIM1 and 2-aminoethyldiphenyl borate (2-APB)
-
Yamashita M, Somasundaram A & Prakriya M (2011). Competitive modulation of CRAC channel gating by STIM1 and 2-aminoethyldiphenyl borate (2-APB). J Biol Chem 286, 9429-9442.
-
(2011)
J Biol Chem
, vol.286
, pp. 9429-9442
-
-
Yamashita, M.1
Somasundaram, A.2
Prakriya, M.3
-
31
-
-
61849107063
-
SOAR and the polybasic STIM1 domains gate and regulate Orai channels
-
Yuan JP, Zeng W, Dorwart MR, Choi YJ, Worley PF & Muallem S (2009). SOAR and the polybasic STIM1 domains gate and regulate Orai channels. Nat Cell Biol 11, 337-343.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 337-343
-
-
Yuan, J.P.1
Zeng, W.2
Dorwart, M.R.3
Choi, Y.J.4
Worley, P.F.5
Muallem, S.6
-
32
-
-
2942640371
-
Photobleaching-corrected FRET efficiency imaging of live cells
-
Zal T & Gascoigne NR (2004). Photobleaching-corrected FRET efficiency imaging of live cells. Biophys J 86, 3923-3939.
-
(2004)
Biophys J
, vol.86
, pp. 3923-3939
-
-
Zal, T.1
Gascoigne, N.R.2
-
33
-
-
84876522211
-
2+ (CRAC) channel activation
-
2+ (CRAC) channel activation. J Biol Chem 288, 11263-11272.
-
(2013)
J Biol Chem
, vol.288
, pp. 11263-11272
-
-
Zheng, H.1
Zhou, M.H.2
Hu, C.3
Kuo, E.4
Peng, X.5
Hu, J.6
Kuo, L.7
Zhang, S.L.8
-
34
-
-
79952171014
-
Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry
-
Zheng L, Stathopulos PB, Schindl R, Li GY, Romanin C & Ikura M (2011). Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry. Proc Natl Acad Sci U S A 108, 1337-1342.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1337-1342
-
-
Zheng, L.1
Stathopulos, P.B.2
Schindl, R.3
Li, G.Y.4
Romanin, C.5
Ikura, M.6
-
35
-
-
77449096553
-
STIM1 gates the store-operated calcium channel ORAI1 in vitro
-
Zhou Y, Meraner P, Kwon HT, Machnes D, Oh-hora M, Zimmer J, Huang Y, Stura A, Rao A & Hogan PG (2010). STIM1 gates the store-operated calcium channel ORAI1 in vitro. Nat Struct Mol Biol 17, 112-116.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 112-116
-
-
Zhou, Y.1
Meraner, P.2
Kwon, H.T.3
Machnes, D.4
Oh-hora, M.5
Zimmer, J.6
Huang, Y.7
Stura, A.8
Rao, A.9
Hogan, P.G.10
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