Calpastatin prevents NF-κB-mediated hyperactivation of macrophages and attenuates colitis

Journal of Immunology

Volumn 191, Issue 7, 2013, Pages 3778-3788

  Huang, Zhi ^a,b   Rose, Aaron H ^a   Hoffmann, Fukun W ^a   Hashimoto, Ann S ^a   Bertino, Pietro ^a   Denk, Tobias ^c   Takano, Jiro ^d   Iwata, Nobuhisa ^e   Saido, Takaomi C ^d   Hoffmann, Peter R ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b JINAN UNIVERSITY   (China)

^c MANNHEIM UNIVERSITY OF APPLIED SCIENCES   (Germany)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^e NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; CALPAIN; CALPASTATIN; GAMMA INTERFERON; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOODY DIARRHEA; BONE MARROW; CELL NUCLEUS; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENTERITIS; ENTEROCOCCUS FAECALIS; ENZYME LOCALIZATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREGULATION; MACROPHAGE ACTIVATION; MALE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TISSUE LEVEL; TRANSCRIPTION REGULATION; WEIGHT REDUCTION;

ANIMALS; CALCIUM-BINDING PROTEINS; COLITIS; CYSTEINE PROTEINASE INHIBITORS; CYTOKINES; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATORY BOWEL DISEASES; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; NF-KAPPA B; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 84885158055     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300972     Document Type: Article

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