Sox2 Expression Is Regulated by a Negative Feedback Loop in Embryonic Stem Cells That Involves AKT Signaling and FoxO1

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Ormsbee Golden, Briana D ^a   Wuebben, Erin L ^a   Rizzino, Angie ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIFFERENTIATION; DNA FLANKING REGION; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; FEEDBACK SYSTEM; GENE; GENE EXPRESSION; MOUSE; NONHUMAN; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOX2 GENE;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DOXYCYCLINE; EMBRYONIC STEM CELLS; FEEDBACK, PHYSIOLOGICAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; MICE; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEOSIDES; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS;

EID: 84885148763     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076345     Document Type: Article

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