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Volumn 288, Issue 40, 2013, Pages 28668-28686

Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: Role of mitochondrial reactive oxygen species

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; ENDOTHELIAL NITRIC-OXIDE SYNTHASE (ENOS); FIBRONECTIN EXPRESSION; MESANGIAL CELLS; NADPH OXIDASE; NITRIC-OXIDE SYNTHASE; REACTIVE OXYGEN SPECIES;

EID: 84885118956     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.470971     Document Type: Article
Times cited : (112)

References (78)
  • 1
    • 22344456349 scopus 로고    scopus 로고
    • Insights into the mechanisms of renal fibrosis. Is it possible to achieve regression?
    • Chatziantoniou, C., and Dussaule, J. C. (2005) Insights into the mechanisms of renal fibrosis. Is it possible to achieve regression? Am. J. Physiol. Renal Physiol. 289, F227-F234
    • (2005) Am. J. Physiol. Renal Physiol. , vol.289
    • Chatziantoniou, C.1    Dussaule, J.C.2
  • 3
    • 0032922445 scopus 로고    scopus 로고
    • Mesangial matrix modulation and glomerulosclerosis
    • Fogo, A. B. (1999) Mesangial matrix modulation and glomerulosclerosis. Exp. Nephrol. 7, 147-159
    • (1999) Exp. Nephrol. , vol.7 , pp. 147-159
    • Fogo, A.B.1
  • 4
    • 84859844692 scopus 로고    scopus 로고
    • Mesangial cell biology
    • Abboud, H. E. (2012) Mesangial cell biology. Exp. Cell Res. 318, 979-985
    • (2012) Exp. Cell Res. , vol.318 , pp. 979-985
    • Abboud, H.E.1
  • 5
    • 0034100147 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases
    • Kim, S., and Iwao, H. (2000) Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol. Rev. 52, 11-34
    • (2000) Pharmacol. Rev. , vol.52 , pp. 11-34
    • Kim, S.1    Iwao, H.2
  • 6
    • 84863722393 scopus 로고    scopus 로고
    • Involvement of glomerular renin-angiotensin system (RAS) activation in the development and progression of glomerular injury
    • Kagami S. (2012) Involvement of glomerular renin-angiotensin system (RAS) activation in the development and progression of glomerular injury. Clin. Exp. Nephrol. 16, 214-220
    • (2012) Clin. Exp. Nephrol. , vol.16 , pp. 214-220
    • Kagami, S.1
  • 7
    • 0026657559 scopus 로고
    • Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass
    • Lafayette, R. A., Mayer, G., Park, S. K., and Meyer, T. W. (1992) Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass. J. Clin. Invest. 90, 766-771
    • (1992) J. Clin. Invest. , vol.90 , pp. 766-771
    • Lafayette, R.A.1    Mayer, G.2    Park, S.K.3    Meyer, T.W.4
  • 9
    • 0036435877 scopus 로고    scopus 로고
    • Angiotensin II and growth factors in the pathogenesis of diabetic nephropathy
    • Rincon-Choles, H., Kasinath, B. S., Gorin, Y., and Abboud, H. E. (2002) Angiotensin II and growth factors in the pathogenesis of diabetic nephropathy. Kidney Int. Suppl. 82, S8-S11
    • (2002) Kidney Int. Suppl. , vol.82
    • Rincon-Choles, H.1    Kasinath, B.S.2    Gorin, Y.3    Abboud, H.E.4
  • 11
    • 79954570719 scopus 로고    scopus 로고
    • Myofibroblast differentiation during fibrosis. Role of NAD(P)H oxidases
    • Barnes, J. L., and Gorin, Y. (2011) Myofibroblast differentiation during fibrosis. Role of NAD(P)H oxidases. Kidney Int. 79, 944-956
    • (2011) Kidney Int. , vol.79 , pp. 944-956
    • Barnes, J.L.1    Gorin, Y.2
  • 12
    • 84861062943 scopus 로고    scopus 로고
    • Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
    • Lassègue, B., San Martín, A., Griendling, K. K. (2012) Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ. Res. 110, 1364-1390
    • (2012) Circ. Res. , vol.110 , pp. 1364-1390
    • Lassègue, B.1    San Martín, A.2    Griendling, K.K.3
  • 13
    • 84877046009 scopus 로고    scopus 로고
    • Nox4 and diabetic nephropathy: With a friend like this, who needs enemies? Free Radic
    • Gorin, Y., and Block, K. (2013) Nox4 and diabetic nephropathy: With a friend like this, who needs enemies? Free Radic. Biol. Med. 61C, 130-142
    • (2013) Biol. Med. , vol.61 C , pp. 130-142
    • Gorin, Y.1    Block, K.2
  • 14
    • 84880176927 scopus 로고    scopus 로고
    • Nox as a target for diabetic complications
    • Gorin, Y., and Block, K. (2013) Nox as a target for diabetic complications. Clin. Sci. (Lond.) 125, 361-382
    • (2013) Clin. Sci. (Lond.) , vol.125 , pp. 361-382
    • Gorin, Y.1    Block, K.2
  • 16
    • 62949101948 scopus 로고    scopus 로고
    • NADPH oxidases and angiotensin II receptor signaling
    • Garrido, A. M., and Griendling, K. K. (2009) NADPH oxidases and angiotensin II receptor signaling. Mol. Cell Endocrinol. 302, 148-158
    • (2009) Mol. Cell Endocrinol. , vol.302 , pp. 148-158
    • Garrido, A.M.1    Griendling, K.K.2
  • 17
    • 84884194246 scopus 로고    scopus 로고
    • Angiotensin II-induced production of mitochondrial reactive oxygen species. Potential mechanisms and relevance for cardiovascular disease
    • Dikalov, S. I., and Nazarewicz, R. R. (2013) Angiotensin II-induced production of mitochondrial reactive oxygen species. Potential mechanisms and relevance for cardiovascular disease. Antioxid. Redox Signal. 19, 1085-1094
    • (2013) Antioxid. Redox Signal. , vol.19 , pp. 1085-1094
    • Dikalov, S.I.1    Nazarewicz, R.R.2
  • 18
    • 80052266526 scopus 로고    scopus 로고
    • Cross talk between mitochondria andNADPHoxidases
    • Dikalov, S. (2011) Cross talk between mitochondria andNADPHoxidases. Dikalov. Free Radic. Biol. Med. 51, 1289-1301
    • (2011) Dikalov. Free Radic. Biol. Med. , vol.51 , pp. 1289-1301
    • Dikalov, S.1
  • 19
    • 84859884412 scopus 로고    scopus 로고
    • Mitochondria and cardiovascular aging
    • Dai, D. F., Rabinovitch, P. S., and Ungvari, Z. (2012) Mitochondria and cardiovascular aging. Circ. Res. 110, 1109-1124
    • (2012) Circ. Res. , vol.110 , pp. 1109-1124
    • Dai, D.F.1    Rabinovitch, P.S.2    Ungvari, Z.3
  • 20
    • 28044455523 scopus 로고    scopus 로고
    • Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney
    • Gorin, Y., Block, K., Hernandez, J., Bhandari, B., Wagner, B., Barnes, J. L., and Abboud, H. E. (2005) Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. J. Biol. Chem. 280, 39616-39626
    • (2005) J. Biol. Chem. , vol.280 , pp. 39616-39626
    • Gorin, Y.1    Block, K.2    Hernandez, J.3    Bhandari, B.4    Wagner, B.5    Barnes, J.L.6    Abboud, H.E.7
  • 21
    • 70149091965 scopus 로고    scopus 로고
    • Subcellular localization of Nox4 and regulation in diabetes
    • Block, K., Gorin, Y., and Abboud, H. E. (2009) Subcellular localization of Nox4 and regulation in diabetes. Proc. Natl. Acad. Sci. U.S.A. 106, 14385-14390
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 14385-14390
    • Block, K.1    Gorin, Y.2    Abboud, H.E.3
  • 22
    • 84863631208 scopus 로고    scopus 로고
    • Angiotensin II-induced mitochondrial Nox4 is a major endogenous source of oxidative stress in kidney tubular cells
    • Kim, S. M., Kim, Y. G., Jeong, K. H., Lee, S. H., Lee, T. W., Ihm, C. G., and Moon, J. Y. (2012) Angiotensin II-induced mitochondrial Nox4 is a major endogenous source of oxidative stress in kidney tubular cells. PLoS One 7, e39739
    • (2012) PLoS One , vol.7
    • Kim, S.M.1    Kim, Y.G.2    Jeong, K.H.3    Lee, S.H.4    Lee, T.W.5    Ihm, C.G.6    Moon, J.Y.7
  • 23
    • 84874918845 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species (ROS) generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells
    • Shah, A., Xia, L., Goldberg, H., Lee, K. W., Quaggin, S. E., and Fantus, I. G. (2013) Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species (ROS) generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells. J. Biol. Chem. 288, 6835-6848
    • (2013) J. Biol. Chem. , vol.288 , pp. 6835-6848
    • Shah, A.1    Xia, L.2    Goldberg, H.3    Lee, K.W.4    Quaggin, S.E.5    Fantus, I.G.6
  • 25
    • 33750897892 scopus 로고    scopus 로고
    • Arachidonic acid-dependent activation of a p22phox-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin expression via Akt/PKB
    • Block, K., Ricono, J. M., Lee, D. Y., Bhandari, B., Choudhury, G. G., Abboud, H. E., and Gorin, Y. (2006) Arachidonic acid-dependent activation of a p22phox-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin expression via Akt/PKB. Antioxid. Redox Signal. 8, 1497-1508
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 1497-1508
    • Block, K.1    Ricono, J.M.2    Lee, D.Y.3    Bhandari, B.4    Choudhury, G.G.5    Abboud, H.E.6    Gorin, Y.7
  • 26
    • 53049098763 scopus 로고    scopus 로고
    • Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II. Role in mesangial cell hypertrophy and fibronectin expression
    • Block, K., Eid, A., Griendling, K. K., Lee, D. Y., Wittrant, Y., and Gorin, Y. (2008) Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II. Role in mesangial cell hypertrophy and fibronectin expression. J. Biol. Chem. 283, 24061-24076
    • (2008) J. Biol. Chem. , vol.283 , pp. 24061-24076
    • Block, K.1    Eid, A.2    Griendling, K.K.3    Lee, D.Y.4    Wittrant, Y.5    Gorin, Y.6
  • 27
    • 1542283780 scopus 로고    scopus 로고
    • Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease
    • Alp, N. J., and Channon, K. M. (2004) Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease. Arterioscler. Thromb. Vasc. Biol. 24, 413-420
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 413-420
    • Alp, N.J.1    Channon, K.M.2
  • 28
  • 29
    • 84857438179 scopus 로고    scopus 로고
    • Tackling endothelial dysfunction by modulating NOS uncoupling. New insights into its pathogenesis and therapeutic possibilities
    • Kietadisorn, R., Juni, R. P., and Moens, A. L. (2012) Tackling endothelial dysfunction by modulating NOS uncoupling. New insights into its pathogenesis and therapeutic possibilities. Am. J. Physiol. Endocrinol. Metab. 302, E481-E95
    • (2012) Am. J. Physiol. Endocrinol. Metab. , vol.302
    • Kietadisorn, R.1    Juni, R.P.2    Moens, A.L.3
  • 30
    • 49849084827 scopus 로고    scopus 로고
    • Redox control of endothelial function and dysfunction. Molecular mechanisms and therapeutic opportunities
    • Thomas, S. R., Witting, P. K., and Drummond, G. R. (2008) Redox control of endothelial function and dysfunction. Molecular mechanisms and therapeutic opportunities. Antioxid. Redox Signal. 10, 1713-1765
    • (2008) Antioxid. Redox Signal. , vol.10 , pp. 1713-1765
    • Thomas, S.R.1    Witting, P.K.2    Drummond, G.R.3
  • 33
    • 34250816918 scopus 로고    scopus 로고
    • Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice
    • Kanetsuna, Y., Takahashi, K., Nagata, M., Gannon, M. A., Breyer, M. D., Harris, R. C., and Takahashi, T. (2007) Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice. Am. J. Pathol. 170, 1473-1484
    • (2007) Am. J. Pathol. , vol.170 , pp. 1473-1484
    • Kanetsuna, Y.1    Takahashi, K.2    Nagata, M.3    Gannon, M.A.4    Breyer, M.D.5    Harris, R.C.6    Takahashi, T.7
  • 35
    • 84863219375 scopus 로고    scopus 로고
    • Uncoupling endothelial nitric oxide synthase is ameliorated by green tea in experimental diabetes by re-establishing tetrahydrobiopterin levels
    • Faria, A. M., Papadimitriou, A., Silva, K. C., Lopes de Faria, J. M., and Lopes de Faria, J. B. (2012) Uncoupling endothelial nitric oxide synthase is ameliorated by green tea in experimental diabetes by re-establishing tetrahydrobiopterin levels. Diabetes 61, 1838-1847
    • (2012) Diabetes , vol.61 , pp. 1838-1847
    • Faria, A.M.1    Papadimitriou, A.2    Silva, K.C.3    Lopes De Faria, J.M.4    Lopes De Faria, J.B.5
  • 36
    • 33847783375 scopus 로고    scopus 로고
    • Regulation of STIM1, store-operated Ca2+ influx, and nitric oxide generation by retinoic acid in rat mesangial cells
    • Zhang, W., Meng, H., Li, Z. H., Shu, Z., Ma, X., and Zhang, B. X. (2007) Regulation of STIM1, store-operated Ca2+ influx, and nitric oxide generation by retinoic acid in rat mesangial cells. Am. J. Physiol. Renal Physiol. 292, F1054-F1064
    • (2007) Am. J. Physiol. Renal Physiol. , vol.292
    • Zhang, W.1    Meng, H.2    Li, Z.H.3    Shu, Z.4    Ma, X.5    Zhang, B.X.6
  • 37
    • 56749182381 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy
    • Satoh, M., Fujimoto, S., Arakawa, S., Yada, T., Namikoshi, T., Haruna, Y., Horike, H., Sasaki, T., and Kashihara, N. (2008) Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy. Nephrol. Dial. Transplant. 23, 3806-3813
    • (2008) Nephrol. Dial. Transplant. , vol.23 , pp. 3806-3813
    • Satoh, M.1    Fujimoto, S.2    Arakawa, S.3    Yada, T.4    Namikoshi, T.5    Haruna, Y.6    Horike, H.7    Sasaki, T.8    Kashihara, N.9
  • 38
    • 3843140495 scopus 로고    scopus 로고
    • Renal nitric oxide production is decreased in diabetic rats and improved by AT1 receptor blockade
    • Awad, A. S., Webb, R. L., Carey, R. M., and Siragy, H. M. (2004) Renal nitric oxide production is decreased in diabetic rats and improved by AT1 receptor blockade. J. Hypertens. 22, 1571-1577
    • (2004) J. Hypertens. , vol.22 , pp. 1571-1577
    • Awad, A.S.1    Webb, R.L.2    Carey, R.M.3    Siragy, H.M.4
  • 39
    • 83455208131 scopus 로고    scopus 로고
    • IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells
    • New, D. D., Block, K., Bhandhari, B., Gorin, Y., and Abboud H. E. (2012) IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells. Am. J. Physiol. Cell Physiol. 302, C122-C130
    • (2012) Am. J. Physiol. Cell Physiol. , vol.302
    • New, D.D.1    Block, K.2    Bhandhari, B.3    Gorin, Y.4    Abboud, H.E.5
  • 40
    • 78549248891 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes
    • Eid, A. A., Ford, B. M., Block, K., Kasinath, B. S., and Gorin, Y., Ghosh-Choudhury, G., Barnes, J. L., and Abboud, H. E. (2010) AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes. J. Biol. Chem. 285, 37503-37512
    • (2010) J. Biol. Chem. , vol.285 , pp. 37503-37512
    • Eid, A.A.1    Ford, B.M.2    Block, K.3    Kasinath, B.S.4    Gorin, Y.5    Ghosh-Choudhury, G.6    Barnes, J.L.7    Abboud, H.E.8
  • 41
    • 0036199685 scopus 로고    scopus 로고
    • Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
    • Zou, M. H., Shi, C., and Cohen, R. A. (2002) Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J. Clin. Invest. 109, 817-826
    • (2002) J. Clin. Invest. , vol.109 , pp. 817-826
    • Zou, M.H.1    Shi, C.2    Cohen, R.A.3
  • 45
    • 31644439543 scopus 로고    scopus 로고
    • VEGF regulation of endothelial nitric oxide synthase in glomerular endothelial cells
    • Feliers, D., Chen, X., Akis, N., Choudhury, G. G., Madaio, M., and Kasinath, B. S. (2005) VEGF regulation of endothelial nitric oxide synthase in glomerular endothelial cells. Kidney Int. 68, 1648-1659
    • (2005) Kidney Int. , vol.68 , pp. 1648-1659
    • Feliers, D.1    Chen, X.2    Akis, N.3    Choudhury, G.G.4    Madaio, M.5    Kasinath, B.S.6
  • 46
    • 34648834521 scopus 로고    scopus 로고
    • Superoxide generation from nitric oxide synthases
    • Xia, Y. (2007) Superoxide generation from nitric oxide synthases. Antioxid. Redox Signal. 9, 1773-1778
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 1773-1778
    • Xia, Y.1
  • 47
    • 33745699168 scopus 로고    scopus 로고
    • Nitric oxide in the kidney. Functions and regulation of synthesis
    • Mount, P. F., and Power, D. A. (2006) Nitric oxide in the kidney. Functions and regulation of synthesis. Acta Physiol. (Oxf.) 187, 433-446
    • (2006) Acta Physiol. (Oxf.) , vol.187 , pp. 433-446
    • Mount, P.F.1    Power, D.A.2
  • 48
    • 0037155923 scopus 로고    scopus 로고
    • Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor- activation in mesangial cells
    • Wang, S., Shiva, S., Poczatek, M. H., Darley-Usmar, V., and Murphy-Ullrich, J. E. (2002) Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor- activation in mesangial cells. J. Biol. Chem. 277, 9880-9888
    • (2002) J. Biol. Chem. , vol.277 , pp. 9880-9888
    • Wang, S.1    Shiva, S.2    Poczatek, M.H.3    Darley-Usmar, V.4    Murphy-Ullrich, J.E.5
  • 50
    • 26244444476 scopus 로고    scopus 로고
    • Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
    • Martyn, K. D., Frederick, L. M., von Loehneysen, K., Dinauer, M. C., and Knaus, U. G. (2006) Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal. 18, 69-82
    • (2006) Cell Signal. , vol.18 , pp. 69-82
    • Martyn, K.D.1    Frederick, L.M.2    Von Loehneysen, K.3    Dinauer, M.C.4    Knaus, U.G.5
  • 52
  • 53
    • 79957484696 scopus 로고    scopus 로고
    • No superoxide-no stress? Nox4, the good NADPH oxidase! Arterioscler
    • Brandes, R. P., Takac, I., and Schröder, K. (2011) No superoxide-no stress? Nox4, the good NADPH oxidase! Arterioscler. Thromb. Vasc. Biol. 31, 1255-1257
    • (2011) Thromb. Vasc. Biol. , vol.31 , pp. 1255-1257
    • Brandes, R.P.1    Takac, I.2    Schröder, K.3
  • 58
    • 84866134987 scopus 로고    scopus 로고
    • The p47phox-and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes
    • Youn, J. Y., Gao, L., and Cai, H. (2012) The p47phox-and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes. Diabetologia 55, 2069-2079
    • (2012) Diabetologia , vol.55 , pp. 2069-2079
    • Youn, J.Y.1    Gao, L.2    Cai, H.3
  • 59
    • 78650880799 scopus 로고    scopus 로고
    • Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase
    • Zhang, M., Song, P., Xu, J., and Zou, M. H. (2011) Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase. Arterioscler. Thromb. Vasc. Biol. 31, 125-132
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 125-132
    • Zhang, M.1    Song, P.2    Xu, J.3    Zou, M.H.4
  • 60
    • 33751178591 scopus 로고    scopus 로고
    • Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid. Role of NAD(P)H oxidase-derived superoxide and peroxynitrite
    • Xu, J., Xie, Z., Reece, R., Pimental, D., and Zou, M. H. (2006) Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid. Role of NAD(P)H oxidase-derived superoxide and peroxynitrite. Arterioscler. Thromb. Vasc. Biol. 26, 2688-2695
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 2688-2695
    • Xu, J.1    Xie, Z.2    Reece, R.3    Pimental, D.4    Zou, M.H.5
  • 61
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factor-1-induced differentiation of cardiac fibroblasts into myofibroblasts
    • Cucoranu, I., Clempus, R., Dikalova, A., Phelan, P. J., Ariyan, S., Dikalov, S., and Sorescu, D. (2005) NAD(P)H oxidase 4 mediates transforming growth factor-1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ. Res. 97, 900-907
    • (2005) Circ. Res. , vol.97 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 64
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco, F., Brownlee, M. (2010) Oxidative stress and diabetic complications. Circ. Res. 107, 1058-1070
    • (2010) Circ. Res. , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 66
    • 41949104144 scopus 로고    scopus 로고
    • Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction. Linking mitochondrial oxidative damage and vascular endothelial dysfunction
    • Doughan, A. K., Harrison, D. G., and Dikalov, S. I. (2008) Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction. Linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ. Res. 102, 488-496
    • (2008) Circ. Res. , vol.102 , pp. 488-496
    • Doughan, A.K.1    Harrison, D.G.2    Dikalov, S.I.3
  • 70
    • 79957933470 scopus 로고    scopus 로고
    • Nitric oxide signaling. Classical, less classical, and nonclassical mechanisms
    • Martínez-Ruiz, A., Cadenas, S., and Lamas, S. (2011) Nitric oxide signaling. Classical, less classical, and nonclassical mechanisms. Free Radic. Biol. Med. 51, 17-29
    • (2011) Free Radic. Biol. Med. , vol.51 , pp. 17-29
    • Martínez-Ruiz, A.1    Cadenas, S.2    Lamas, S.3
  • 71
    • 0029964086 scopus 로고    scopus 로고
    • Nitric oxide diffusion in membranes determined by fluorescence quenching
    • Denicola, A., Souza, J. M., Radi, R., and Lissi E. (1996) Nitric oxide diffusion in membranes determined by fluorescence quenching. Arch. Biochem. Biophys. 328, 208-212
    • (1996) Arch. Biochem. Biophys. , vol.328 , pp. 208-212
    • Denicola, A.1    Souza, J.M.2    Radi, R.3    Lissi, E.4
  • 72
    • 11144356896 scopus 로고    scopus 로고
    • Docking of endothelial nitric oxide synthase (eNOS) to the mitochondrial outer membrane. A pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria
    • Gao, S., Chen, J., Brodsky, S. V., Huang, H., Adler, S., Lee, J. H., Dhadwal, N., Cohen-Gould, L., Gross, S. S., and Goligorsky, M. S. (2004) Docking of endothelial nitric oxide synthase (eNOS) to the mitochondrial outer membrane. A pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondria. J. Biol. Chem. 279, 15968-15974
    • (2004) J. Biol. Chem. , vol.279 , pp. 15968-15974
    • Gao, S.1    Chen, J.2    Brodsky, S.V.3    Huang, H.4    Adler, S.5    Lee, J.H.6    Dhadwal, N.7    Cohen-Gould, L.8    Gross, S.S.9    Goligorsky, M.S.10
  • 73
    • 84874771073 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine induces endothelial nitric oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1
    • Rafikov, R., Rafikova, O., Aggarwal, S., Gross, C., Sun, X., Desai, J., Fulton, D., and Black, S. M. (2013) Asymmetric dimethylarginine induces endothelial nitric oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1. J. Biol. Chem. 288, 6212-6226
    • (2013) J. Biol. Chem. , vol.288 , pp. 6212-6226
    • Rafikov, R.1    Rafikova, O.2    Aggarwal, S.3    Gross, C.4    Sun, X.5    Desai, J.6    Fulton, D.7    Black, S.M.8
  • 75
    • 77953610731 scopus 로고    scopus 로고
    • Glycated albumin activates NADPH oxidase in rat mesangial cells through up-regulation of p47phox
    • Li, Y., and Wang, S. (2010) Glycated albumin activates NADPH oxidase in rat mesangial cells through up-regulation of p47phox. Biochem. Biophys. Res. Commun. 397, 5-11
    • (2010) Biochem. Biophys. Res. Commun. , vol.397 , pp. 5-11
    • Li, Y.1    Wang, S.2
  • 77
    • 0025720217 scopus 로고
    • Functional expression ofNADPHoxidase components (α-and β-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cells
    • Radeke, H. H., Cross, A. R., Hancock, J. T., Jones, O. T., Nakamura, M., Kaever, V., and Resch, K. (1991) Functional expression ofNADPHoxidase components (α-and β-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cells. J. Biol. Chem. 266, 21025-21029
    • (1991) J. Biol. Chem. , vol.266 , pp. 21025-21029
    • Radeke, H.H.1    Cross, A.R.2    Hancock, J.T.3    Jones, O.T.4    Nakamura, M.5    Kaever, V.6    Resch, K.7


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