메뉴 건너뛰기




Volumn 34, Issue 10, 2013, Pages 2389-2400

Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model

Author keywords

[No Author keywords available]

Indexed keywords

SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 84885118876     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt175     Document Type: Article
Times cited : (8)

References (74)
  • 1
    • 84863707351 scopus 로고    scopus 로고
    • Cancer treatment and survivorship statistics, 2012
    • Siegel, R. et al. (2012) Cancer treatment and survivorship statistics, 2012. CA. Cancer J. Clin., 62, 220-241.
    • (2012) CA. Cancer J. Clin. , vol.62 , pp. 220-241
    • Siegel, R.1
  • 2
    • 77952883863 scopus 로고    scopus 로고
    • Molecular prognostic markers in papillary and follicular thyroid cancer: Current status and future directions
    • Handkiewicz-Junak, D. et al. (2010) Molecular prognostic markers in papillary and follicular thyroid cancer: Current status and future directions. Mol. Cell. Endocrinol., 322, 8-28.
    • (2010) Mol. Cell. Endocrinol. , vol.322 , pp. 8-28
    • Handkiewicz-Junak, D.1
  • 3
    • 56449118024 scopus 로고    scopus 로고
    • Recent advances in molecular biology of thyroid cancer and their clinical implications
    • ix
    • Xing, M. (2008) Recent advances in molecular biology of thyroid cancer and their clinical implications. Otolaryngol. Clin. North Am., 41, 1135-46, ix.
    • (2008) Otolaryngol. Clin. North Am. , vol.41 , pp. 1135-46
    • Xing, M.1
  • 4
    • 12944311040 scopus 로고    scopus 로고
    • Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone
    • Kaneshige, M. et al. (2000) Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc. Natl Acad. Sci. USA, 97, 13209-13214.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 13209-13214
    • Kaneshige, M.1
  • 5
    • 0026320853 scopus 로고
    • Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain
    • Parrilla, R. et al. (1991) Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain. J. Clin. Invest., 88, 2123-2130.
    • (1991) J. Clin. Invest. , vol.88 , pp. 2123-2130
    • Parrilla, R.1
  • 6
    • 6444245375 scopus 로고    scopus 로고
    • Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis
    • Suzuki, H. et al. (2002) Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis. Thyroid, 12, 963-969.
    • (2002) Thyroid , vol.12 , pp. 963-969
    • Suzuki, H.1
  • 7
    • 32444445924 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor
    • USA
    • Furuya, F. et al. (2006) Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor. Proc. Natl Acad. Sci. USA, 103, 1780-1785.
    • (2006) Proc. Natl Acad. Sci. , vol.103 , pp. 1780-1785
    • Furuya, F.1
  • 8
    • 0035881322 scopus 로고    scopus 로고
    • Overexpression and overactivation of Akt in thyroid carcinoma
    • Ringel, M.D. et al. (2001) Overexpression and overactivation of Akt in thyroid carcinoma. Cancer Res., 61, 6105-6111.
    • (2001) Cancer Res. , vol.61 , pp. 6105-6111
    • Ringel, M.D.1
  • 9
    • 77950267114 scopus 로고    scopus 로고
    • Growth activation alone is not sufficient to cause metastatic thyroid cancer in a mouse model of follicular thyroid carcinoma
    • Lu, C. et al. (2010) Growth activation alone is not sufficient to cause metastatic thyroid cancer in a mouse model of follicular thyroid carcinoma. Endocrinology, 151, 1929-1939.
    • (2010) Endocrinology , vol.151 , pp. 1929-1939
    • Lu, C.1
  • 10
    • 33750592404 scopus 로고    scopus 로고
    • Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression
    • Ying, H. et al. (2006) Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression. J. Clin. Invest., 116, 2972-2984.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2972-2984
    • Ying, H.1
  • 11
    • 34447109798 scopus 로고    scopus 로고
    • The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer
    • Kim, C.S. et al. (2007) The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer. Carcinogenesis, 28, 932-939.
    • (2007) Carcinogenesis , vol.28 , pp. 932-939
    • Kim, C.S.1
  • 12
    • 47049089117 scopus 로고    scopus 로고
    • Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor
    • Guigon, C.J. et al. (2008) Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor. Mol. Cell. Biol., 28, 4598-4608.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 4598-4608
    • Guigon, C.J.1
  • 13
    • 0031246430 scopus 로고    scopus 로고
    • Ratio-based decisions and the quantitative analysis of cDNA microarray images
    • Chen, Y. et al. (1997) Ratio-based decisions and the quantitative analysis of cDNA microarray images. J. Biomed. Opt., 2, 364-374.
    • (1997) J. Biomed. Opt. , vol.2 , pp. 364-374
    • Chen, Y.1
  • 14
    • 0034954414 scopus 로고    scopus 로고
    • Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks
    • Khan, J. et al. (2001) Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks. Nat. Med., 7, 673-679.
    • (2001) Nat. Med. , vol.7 , pp. 673-679
    • Khan, J.1
  • 15
    • 0034094855 scopus 로고    scopus 로고
    • Simple method for preparation of fluor/hapten-labeled dUTP
    • Nimmakayalu, M. et al. (2000) Simple method for preparation of fluor/hapten-labeled dUTP. Biotechniques, 28, 518-522.
    • (2000) Biotechniques , vol.28 , pp. 518-522
    • Nimmakayalu, M.1
  • 16
    • 78049499915 scopus 로고    scopus 로고
    • Tumor suppressor action of liganded thyroid hormone receptor beta by direct repression of beta-catenin gene expression
    • Guigon, C.J. et al. (2010) Tumor suppressor action of liganded thyroid hormone receptor beta by direct repression of beta-catenin gene expression. Endocrinology, 151, 5528-5536.
    • (2010) Endocrinology , vol.151 , pp. 5528-5536
    • Guigon, C.J.1
  • 17
    • 84886748450 scopus 로고    scopus 로고
    • Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actions
    • Kim, D.W. et al. (2012) Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actions. Am. J. Cancer Res., 2, 606-619.
    • (2012) Am. J. Cancer Res. , vol.2 , pp. 606-619
    • Kim, D.W.1
  • 18
    • 29144473333 scopus 로고    scopus 로고
    • Diagnostic and prognostic value of angiogenesismodulating genes in malignant thyroid neoplasms
    • discussion 1109
    • Kebebew, E. et al. (2005) Diagnostic and prognostic value of angiogenesismodulating genes in malignant thyroid neoplasms. Surgery, 138, 1102-9; discussion 1109.
    • (2005) Surgery , vol.138 , pp. 1102-9
    • Kebebew, E.1
  • 19
    • 33847298591 scopus 로고    scopus 로고
    • Gene expression and functional evidence of epithelial- to-mesenchymal transition in papillary thyroid carcinoma invasion
    • USA
    • Vasko, V. et al. (2007) Gene expression and functional evidence of epithelial- to-mesenchymal transition in papillary thyroid carcinoma invasion. Proc. Natl Acad. Sci. USA, 104, 2803-2808.
    • (2007) Proc. Natl Acad. Sci. , vol.104 , pp. 2803-2808
    • Vasko, V.1
  • 20
    • 0026774093 scopus 로고
    • An immunohistochemical study of epithelial membrane antigen, cytokeratin, and vimentin in papillary thyroid carcinoma. Recognition of lethal and favorable prognostic types
    • Yamamoto, Y. et al. (1992) An immunohistochemical study of epithelial membrane antigen, cytokeratin, and vimentin in papillary thyroid carcinoma. Recognition of lethal and favorable prognostic types. Cancer, 70, 2326-2333.
    • (1992) Cancer , vol.70 , pp. 2326-2333
    • Yamamoto, Y.1
  • 21
    • 0034738957 scopus 로고    scopus 로고
    • RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma
    • Corvi, R. et al. (2000) RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma. Oncogene, 19, 4236-4242.
    • (2000) Oncogene , vol.19 , pp. 4236-4242
    • Corvi, R.1
  • 22
    • 34347356501 scopus 로고    scopus 로고
    • Expression of prolactin receptor and prolactin in normal and malignant thyroid: a tissue microarray study
    • Costa, P. et al. (2006) Expression of prolactin receptor and prolactin in normal and malignant thyroid: a tissue microarray study. Endocr. Pathol., 17, 377-386.
    • (2006) Endocr. Pathol. , vol.17 , pp. 377-386
    • Costa, P.1
  • 23
    • 79960037443 scopus 로고    scopus 로고
    • TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells
    • Anania, M.C. et al. (2011) TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells. Oncogene, 30, 3011-3023.
    • (2011) Oncogene , vol.30 , pp. 3011-3023
    • Anania, M.C.1
  • 24
    • 84865597197 scopus 로고    scopus 로고
    • TGF-β - an excellent servant but a bad master
    • Kubiczkova, L. et al. (2012) TGF-β - an excellent servant but a bad master. J. Transl. Med., 10, 183.
    • (2012) J. Transl. Med. , vol.10 , pp. 183
    • Kubiczkova, L.1
  • 25
    • 0026783009 scopus 로고
    • cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta
    • Skonier, J. et al. (1992) cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta. DNA Cell Biol., 11, 511-522.
    • (1992) DNA Cell Biol. , vol.11 , pp. 511-522
    • Skonier, J.1
  • 26
    • 77950903213 scopus 로고    scopus 로고
    • Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells
    • USA
    • de Graauw, M. et al. (2010) Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells. Proc. Natl Acad. Sci. USA, 107, 6340-6345.
    • (2010) Proc. Natl Acad. Sci. , vol.107 , pp. 6340-6345
    • de Graauw, M.1
  • 27
    • 0036387022 scopus 로고    scopus 로고
    • Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells
    • Isono, M. et al. (2002) Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells. Biochem. Biophys. Res. Commun., 296, 1356-1365.
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 1356-1365
    • Isono, M.1
  • 28
    • 2942755760 scopus 로고    scopus 로고
    • Inhibition of hepatic transcriptional induction of lipopolysaccharide-binding protein by transforming-growth-factor beta
    • Hallatschek, W. et al. (2004) Inhibition of hepatic transcriptional induction of lipopolysaccharide-binding protein by transforming-growth-factor beta 1. Eur. J. Immunol., 34, 1441-1450.
    • (2004) 1.Eur. J. Immunol. , vol.34 , pp. 1441-1450
    • Hallatschek, W.1
  • 29
    • 0028985892 scopus 로고
    • Transforming growth factor-beta and forskolin increase all classes of insulin-like growth factor-I transcripts in normal human osteoblast-like cells
    • Okazaki, R. et al. (1995) Transforming growth factor-beta and forskolin increase all classes of insulin-like growth factor-I transcripts in normal human osteoblast-like cells. Biochem. Biophys. Res. Commun., 207, 963-970.
    • (1995) Biochem. Biophys. Res. Commun. , vol.207 , pp. 963-970
    • Okazaki, R.1
  • 30
    • 80355129706 scopus 로고    scopus 로고
    • Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells
    • Rogel, M.R. et al. (2011) Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells. FASEB J., 25, 3873-3883.
    • (2011) FASEB J. , vol.25 , pp. 3873-3883
    • Rogel, M.R.1
  • 31
    • 26444490645 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 regulation of laminin gamma1 and fibronectin expression and survival of mouse mesangial cells
    • Jiang, Y. et al. (2005) Transforming growth factor-beta1 regulation of laminin gamma1 and fibronectin expression and survival of mouse mesangial cells. Mol. Cell. Biochem., 278, 165-175.
    • (2005) Mol. Cell. Biochem. , vol.278 , pp. 165-175
    • Jiang, Y.1
  • 32
    • 0027144601 scopus 로고
    • Transforming growth factor-beta 1 induces collagen IV gene expression in NIH-3T3 cells
    • Grande, J. et al. (1993) Transforming growth factor-beta 1 induces collagen IV gene expression in NIH-3T3 cells. Lab. Invest., 69, 387-395.
    • (1993) Lab. Invest. , vol.69 , pp. 387-395
    • Grande, J.1
  • 33
    • 2542464186 scopus 로고    scopus 로고
    • Opposite Smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming growth factor-beta
    • Calonge, M.J. et al. (2004) Opposite Smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming growth factor-beta. J. Biol. Chem., 279, 23759-23765.
    • (2004) J. Biol. Chem. , vol.279 , pp. 23759-23765
    • Calonge, M.J.1
  • 34
    • 79956265753 scopus 로고    scopus 로고
    • Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer
    • Sayeed, A. et al. (2010) Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer. Cell Death Dis., 1, e53.
    • (2010) Cell Death Dis. , vol.1
    • Sayeed, A.1
  • 35
    • 16644398740 scopus 로고    scopus 로고
    • Transforming growth factor beta stimulation of biglycan gene expression is potentially mediated by sp1 binding factors
    • Heegaard, A.M. et al. (2004) Transforming growth factor beta stimulation of biglycan gene expression is potentially mediated by sp1 binding factors. J. Cell. Biochem., 93, 463-475.
    • (2004) J. Cell. Biochem. , vol.93 , pp. 463-475
    • Heegaard, A.M.1
  • 36
    • 0023253216 scopus 로고
    • Transforming growth factor type beta (TGF beta) inhibits G1 to S transition, but not activation of human B lymphocytes
    • Smeland, E.B. et al. (1987) Transforming growth factor type beta (TGF beta) inhibits G1 to S transition, but not activation of human B lymphocytes. Exp. Cell Res., 171, 213-222.
    • (1987) Exp. Cell Res. , vol.171 , pp. 213-222
    • Smeland, E.B.1
  • 37
    • 0041829207 scopus 로고    scopus 로고
    • TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice
    • Kenyon, N.J. et al. (2003) TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice. Thorax, 58, 772-777.
    • (2003) Thorax , vol.58 , pp. 772-777
    • Kenyon, N.J.1
  • 38
    • 84882454061 scopus 로고    scopus 로고
    • AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia
    • (3 September 2012, date last accessed)
    • Norris, A. et al. (2012) AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia. Oncogene. http://dx.doi.org/10.1038/onc.2012.394 (3 September 2012, date last accessed).
    • (2012) Oncogene
    • Norris, A.1
  • 39
    • 68549130831 scopus 로고    scopus 로고
    • Increased IkappaB alpha expression is essential for the tolerogenic property of TGF-beta-exposed APCs
    • Ghafoori, P. et al. (2009) Increased IkappaB alpha expression is essential for the tolerogenic property of TGF-beta-exposed APCs. FASEB J., 23, 2226-2234.
    • (2009) FASEB J. , vol.23 , pp. 2226-2234
    • Ghafoori, P.1
  • 40
    • 14644443540 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces LMO7 while enhancing the invasiveness of rat ascites hepatoma cells
    • Nakamura, H. et al. (2005) Transforming growth factor-beta1 induces LMO7 while enhancing the invasiveness of rat ascites hepatoma cells. Cancer Lett., 220, 95-99.
    • (2005) Cancer Lett. , vol.220 , pp. 95-99
    • Nakamura, H.1
  • 41
    • 77950095763 scopus 로고    scopus 로고
    • TGFbeta-mediated upregulation of hepatic miR- 181b promotes hepatocarcinogenesis by targeting TIMP3
    • Wang, B. et al. (2010) TGFbeta-mediated upregulation of hepatic miR- 181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene, 29, 1787-1797.
    • (2010) Oncogene , vol.29 , pp. 1787-1797
    • Wang, B.1
  • 42
    • 80052835620 scopus 로고    scopus 로고
    • Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-β1-dependent human epidermal Langerhans cells
    • Eisenwort, G. et al. (2011) Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-β1-dependent human epidermal Langerhans cells. J. Invest. Dermatol., 131, 2049-2057.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 2049-2057
    • Eisenwort, G.1
  • 43
    • 84862913236 scopus 로고    scopus 로고
    • Enhanced expression of tissue inhibitor of metalloproteinases- 4 gene in human osteoarthritic synovial membranes and its differential regulation by cytokines in chondrocytes
    • Huang, W. et al. (2011) Enhanced expression of tissue inhibitor of metalloproteinases- 4 gene in human osteoarthritic synovial membranes and its differential regulation by cytokines in chondrocytes. Open Rheumatol. J., 5, 81-87.
    • (2011) Open Rheumatol. J. , vol.5 , pp. 81-87
    • Huang, W.1
  • 44
    • 0035967797 scopus 로고    scopus 로고
    • Transcriptional regulation of the lung fatty acid synthase gene by glucocorticoid, thyroid hormone and transforming growth factorbeta 1
    • Lu, Z. et al. (2001) Transcriptional regulation of the lung fatty acid synthase gene by glucocorticoid, thyroid hormone and transforming growth factorbeta 1. Biochim. Biophys. Acta, 1532, 213-222.
    • (2001) Biochim. Biophys. Acta , vol.1532 , pp. 213-222
    • Lu, Z.1
  • 45
    • 80054044729 scopus 로고    scopus 로고
    • Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer
    • Sharma, V. et al. (2011) Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer. Cancer Res., 71, 6438-6449.
    • (2011) Cancer Res. , vol.71 , pp. 6438-6449
    • Sharma, V.1
  • 46
    • 0035847018 scopus 로고    scopus 로고
    • Oncogenic Ki-ras confers a more aggressive colon cancer phenotype through modification of transforming growth factor-beta receptor III
    • Yan, Z. et al. (2001) Oncogenic Ki-ras confers a more aggressive colon cancer phenotype through modification of transforming growth factor-beta receptor III. J. Biol. Chem., 276, 1555-1563.
    • (2001) J. Biol. Chem. , vol.276 , pp. 1555-1563
    • Yan, Z.1
  • 47
    • 0034214211 scopus 로고    scopus 로고
    • Mitogenic conversion of transforming growth factorbeta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer
    • Park, B.J. et al. (2000) Mitogenic conversion of transforming growth factorbeta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer. Cancer Res., 60, 3031-3038.
    • (2000) Cancer Res. , vol.60 , pp. 3031-3038
    • Park, B.J.1
  • 48
    • 0035405349 scopus 로고    scopus 로고
    • Altered expression of TGFB receptors and mitogenic effects of TGFB in pancreatic carcinomas
    • Jonson, T. et al. (2001) Altered expression of TGFB receptors and mitogenic effects of TGFB in pancreatic carcinomas. Int. J. Oncol., 19, 71-81.
    • (2001) Int. J. Oncol. , vol.19 , pp. 71-81
    • Jonson, T.1
  • 49
    • 84862770017 scopus 로고    scopus 로고
    • Regulation of EMT by TGFβ in cancer
    • Heldin, C.H. et al. (2012) Regulation of EMT by TGFβ in cancer. FEBS Lett., 586, 1959-1970.
    • (2012) FEBS Lett. , vol.586 , pp. 1959-1970
    • Heldin, C.H.1
  • 50
    • 77249137734 scopus 로고    scopus 로고
    • The third type III module of human fibronectin mediates cell adhesion and migration
    • Obara, M. et al. (2010) The third type III module of human fibronectin mediates cell adhesion and migration. J. Biochem., 147, 327-335.
    • (2010) J. Biochem. , vol.147 , pp. 327-335
    • Obara, M.1
  • 51
    • 34250901825 scopus 로고    scopus 로고
    • Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion
    • McInroy, L. et al. (2007) Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion. Biochem. Biophys. Res. Commun., 360, 109-114.
    • (2007) Biochem. Biophys. Res. Commun. , vol.360 , pp. 109-114
    • McInroy, L.1
  • 52
    • 18144404148 scopus 로고    scopus 로고
    • Physiological role of collagen XVIII and endostatin
    • Marneros, A.G. et al. (2005) Physiological role of collagen XVIII and endostatin. FASEB J., 19, 716-728.
    • (2005) FASEB J. , vol.19 , pp. 716-728
    • Marneros, A.G.1
  • 53
    • 0037305645 scopus 로고    scopus 로고
    • Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells
    • Gu, Y.C. et al. (2003) Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells. Blood, 101, 877-885.
    • (2003) Blood , vol.101 , pp. 877-885
    • Gu, Y.C.1
  • 54
    • 0027305435 scopus 로고
    • Type IV collagen, laminin, and fibronectin promote the adhesion and migration of rabbit lens epithelial cells in vitro
    • Olivero, D.K. et al. (1993) Type IV collagen, laminin, and fibronectin promote the adhesion and migration of rabbit lens epithelial cells in vitro. Invest. Ophthalmol. Vis. Sci., 34, 2825-2834.
    • (1993) Invest. Ophthalmol. Vis. Sci. , vol.34 , pp. 2825-2834
    • Olivero, D.K.1
  • 55
    • 33845268866 scopus 로고    scopus 로고
    • A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides
    • Lisman, T. et al. (2006) A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides. Blood, 108, 3753-3756.
    • (2006) Blood , vol.108 , pp. 3753-3756
    • Lisman, T.1
  • 56
    • 0035145896 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-4 instigates apoptosis in transformed cardiac fibroblasts
    • Tummalapalli, C.M. et al. (2001) Tissue inhibitor of metalloproteinase-4 instigates apoptosis in transformed cardiac fibroblasts. J. Cell. Biochem., 80, 512-521.
    • (2001) J. Cell. Biochem. , vol.80 , pp. 512-521
    • Tummalapalli, C.M.1
  • 57
    • 33846819015 scopus 로고    scopus 로고
    • Transcriptional regulation of epithelial-mesenchymal transition
    • Teng, Y. et al. (2007) Transcriptional regulation of epithelial-mesenchymal transition. J. Clin. Invest., 117, 304-306.
    • (2007) J. Clin. Invest. , vol.117 , pp. 304-306
    • Teng, Y.1
  • 58
    • 0029060074 scopus 로고
    • Clinical significance of E-cadherin as a prognostic marker in thyroid carcinomas
    • Scheumman, G.F. et al. (1995) Clinical significance of E-cadherin as a prognostic marker in thyroid carcinomas. J. Clin. Endocrinol. Metab., 80, 2168-2172.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 2168-2172
    • Scheumman, G.F.1
  • 59
    • 0141484480 scopus 로고    scopus 로고
    • Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells
    • Sherman-Baust, C.A. et al. (2003) Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells. Cancer Cell, 3, 377-386.
    • (2003) Cancer Cell , vol.3 , pp. 377-386
    • Sherman-Baust, C.A.1
  • 60
    • 33745725773 scopus 로고    scopus 로고
    • Aberrant expression of collagen triple helix repeat containing 1 in human solid cancers
    • Tang, L. et al. (2006) Aberrant expression of collagen triple helix repeat containing 1 in human solid cancers. Clin. Cancer Res., 12, 3716-3722.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 3716-3722
    • Tang, L.1
  • 61
    • 37549053307 scopus 로고    scopus 로고
    • Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling
    • Shintani, Y. et al. (2008) Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling. Am. J. Respir. Cell Mol. Biol., 38, 95-104.
    • (2008) Am. J. Respir. Cell Mol. Biol. , vol.38 , pp. 95-104
    • Shintani, Y.1
  • 62
    • 84869049625 scopus 로고    scopus 로고
    • Native type IV collagen induces an epithelial to mesenchymal transition-like process in mammary epithelial cells MCF10A
    • Espinosa Neira, R. et al. (2012) Native type IV collagen induces an epithelial to mesenchymal transition-like process in mammary epithelial cells MCF10A. Int. J. Biochem. Cell Biol., 44, 2194-2203.
    • (2012) Int. J. Biochem. Cell Biol. , vol.44 , pp. 2194-2203
    • Espinosa Neira, R.1
  • 63
    • 0035470856 scopus 로고    scopus 로고
    • Overexpression of laminin alpha1 chain in colonic cancer cells induces an increase in tumor growth
    • De Arcangelis, A. et al. (2001) Overexpression of laminin alpha1 chain in colonic cancer cells induces an increase in tumor growth. Int. J. Cancer, 94, 44-53.
    • (2001) Int. J. Cancer , vol.94 , pp. 44-53
    • De Arcangelis, A.1
  • 64
    • 21044452016 scopus 로고    scopus 로고
    • Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases
    • Fujita, M. et al. (2005) Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases. Breast Cancer Res., 7, R411-R421.
    • (2005) Breast Cancer Res. , vol.7
    • Fujita, M.1
  • 65
    • 62649098660 scopus 로고    scopus 로고
    • Lipocalin 2 promotes breast cancer progression
    • USA
    • Yang, J. et al. (2009) Lipocalin 2 promotes breast cancer progression. Proc. Natl Acad. Sci. USA, 106, 3913-3918.
    • (2009) Proc. Natl Acad. Sci. , vol.106 , pp. 3913-3918
    • Yang, J.1
  • 66
    • 79955391837 scopus 로고    scopus 로고
    • IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition
    • Walsh, L.A. et al. (2011) IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition. Cell Commun. Signal., 9, 10.
    • (2011) Cell Commun. Signal. , vol.9 , pp. 10
    • Walsh, L.A.1
  • 67
    • 56649108007 scopus 로고    scopus 로고
    • CAMK1D amplification implicated in epithelial- mesenchymal transition in basal-like breast cancer
    • Bergamaschi, A. et al. (2008) CAMK1D amplification implicated in epithelial- mesenchymal transition in basal-like breast cancer. Mol. Oncol., 2, 327-339.
    • (2008) Mol. Oncol. , vol.2 , pp. 327-339
    • Bergamaschi, A.1
  • 68
    • 33845188730 scopus 로고    scopus 로고
    • Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition
    • USA
    • Perez-Pinera, P. et al. (2006) Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition. Proc. Natl Acad. Sci. USA, 103, 17795-17800.
    • (2006) Proc. Natl Acad. Sci. , vol.103 , pp. 17795-17800
    • Perez-Pinera, P.1
  • 69
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • Zeisberg, M. et al. (2009) Biomarkers for epithelial-mesenchymal transitions. J. Clin. Invest., 119, 1429-1437.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1429-1437
    • Zeisberg, M.1
  • 70
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • Grünert, S. et al. (2003) Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat. Rev. Mol. Cell Biol., 4, 657-665.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 657-665
    • Grünert, S.1
  • 71
    • 84863238702 scopus 로고    scopus 로고
    • SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer
    • Kim, W.G. et al. (2012) SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer. Clin. Cancer Res., 18, 1281-1290.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 1281-1290
    • Kim, W.G.1
  • 72
    • 84860437331 scopus 로고    scopus 로고
    • Src-mediated regulation of E-cadherin and EMT in pancreatic cancer
    • Nagathihalli, N.S. et al. (2012) Src-mediated regulation of E-cadherin and EMT in pancreatic cancer. Front. Biosci., 17, 2059-2069.
    • (2012) Front. Biosci. , vol.17 , pp. 2059-2069
    • Nagathihalli, N.S.1
  • 73
    • 36549031307 scopus 로고    scopus 로고
    • TGFbeta-induced EMT requires focal adhesion kinase (FAK) signaling
    • Cicchini, C. et al. (2008) TGFbeta-induced EMT requires focal adhesion kinase (FAK) signaling. Exp. Cell Res., 314, 143-152.
    • (2008) Exp. Cell Res. , vol.314 , pp. 143-152
    • Cicchini, C.1
  • 74
    • 2542426492 scopus 로고    scopus 로고
    • Src SH3/2 domain-mediated peripheral accumulation of Src and phospho-myosin is linked to deregulation of E-cadherin and the epithelial-mesenchymal transition
    • Avizienyte, E. et al. (2004) Src SH3/2 domain-mediated peripheral accumulation of Src and phospho-myosin is linked to deregulation of E-cadherin and the epithelial-mesenchymal transition. Mol. Biol. Cell, 15, 2794-2803.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2794-2803
    • Avizienyte, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.