Constitutive stabilization of hypoxia-inducible factor alpha selectively promotes the self-renewal of mesenchymal progenitors and maintains mesenchymal stromal cells in an undifferentiated state

Experimental and Molecular Medicine

Volumn 45, Issue 9, 2013, Pages

  Park, In Ho ^a   Kim, Kwang Ho ^a   Choi, Hyun Kyung ^a   Shim, Jae Seung ^a   Whang, Soo Young ^a   Hahn, Sang June ^a   Kwon, Oh Joo ^a   Oh, Il Hoan ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Hif 1 ; Hypoxia; MSC; Self renewal

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KRUPPEL LIKE FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4; OSTEOCALCIN; OSTEOPONTIN; TRANSCRIPTION FACTOR NANOG; UBIQUITIN; HIF1A PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; POU5F1 PROTEIN, HUMAN;

ADIPOCYTE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL HYPOXIA; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; COLONY FORMATION; COLONY FORMING UNIT F; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MESENCHYMAL STEM CELL; MESENCHYMAL STROMA CELL; OSTEOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN STABILITY; CYTOLOGY; GENETICS; METABOLISM; PHYSIOLOGY;

CELL DIFFERENTIATION; CELL PROLIFERATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MESENCHYMAL STROMAL CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PROTEIN STABILITY;

EID: 84885113328     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2013.87     Document Type: Article

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