Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: The mild and moderate kidney disease study

Journal of the American Society of Nephrology

Volumn 16, Issue 4, 2005, Pages 1091-1098

  Becker, Bjoern ^a   Kronenberg, Florian ^b   Kielstein, Jan T ^a   Haller, Hermann ^a   Morath, Christian ^c   Ritz, Eberhard ^c   Fliser, Danilo ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GLUCOSE; TRIACYLGLYCEROL; SIGNAL PEPTIDE;

ADULT; AGE; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN SENSITIVITY; KIDNEY DISEASE; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MORBIDITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SEX RATIO; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; COHORT ANALYSIS; HOMEOSTASIS; HOSPITALIZATION; INCIDENCE; INSULIN RESISTANCE; MEDICAL RECORD; MIDDLE AGED; PATHOPHYSIOLOGY; RISK FACTOR; SYNDROME;

ADIPONECTIN; ADULT; CARDIOVASCULAR DISEASES; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HOMEOSTASIS; HUMANS; INCIDENCE; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY DISEASES; MALE; MEDICAL RECORDS; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SYNDROME;

EID: 21344446701     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2004090742     Document Type: Article

References (37)

1. Wirthensohn G, Guder WG: Renal substrate metabolism. Physiol Rev 66: 469-497, 1986
2. Stumvoll M, Chintalapudi U, Perriello G, Welle S, Gutierrez O, Gerich J: Uptake and release of glucose by the human kidney. Postabsorptive rates and responses to epinephrine. J Clin Invest 96: 2528-2533, 1995
3. Cersosimo E, Garlick P, Ferretti J: Insulin regulation of renal glucose metabolism in humans. Am J Physiol 276: E78-E84, 1999
4. Meyer C, Stumvoll M, Dostou J, Welle S, Haymond M, Gerich J: Renal substrate exchange and gluconeogenesis in normal postabsorptive humans. Am J Physiol 282: E428-E434, 2002
5. DeFronzo RA, Alverstrand A, Smith D, Hendler R, Hendler E, Wahren J: Insulin resistance in uremia. J Clin Invest 67: 563-572, 1981
6. Alvestrand A: Carbohydrate and insulin metabolism in renal failure. Kidney Int 52[Suppl 62]: S48-S52, 1997
7. Feneberg R, Sparber M, Veldhuis JD, Mehls O, Ritz E, Schaefer F: Altered temporal organization of plasma insulin oscillations in chronic renal failure. J Clin Endocrinol Metab 87: 1965-1973, 2002
8. Kautzky-Willer A, Pacini G, Barnas U, Ludvik B, Streli C, Graf H, Prager R: Intravenous calcitriol normalizes insulin sensitivity in uremic patients. Kidney Int 47: 200-206, 1995
9. Spaia S, Pangalos M, Askepidis N, Pazarloglou M, Mavropoulou E, Theodoridis S, Dimitrakopoulos K, Milionis A, Vayonas G: Effect of short-term rHuEPO treatment on insulin resistance in haemodialysis patients. Nephron 84: 320-325, 2000
10. Eidemak I, Feldt-Rasmussen B: Kanstrup IL, Nielsen SL, Schmitz O, Strandgaard S: Insulin resistance and hyperinsulinemia in mild to moderate progressive chronic renal failure and its association with aerobic work capacity. Diabetologia 38: 565-572, 1995
11. Fliser D, Pacini G, Engelleiter R, Kautzky-Willer A, Franek E, Ritz E: Insulin resistance and hyperinsulinaemia are present already in patients with incipient renal disease. Kidney Int 53: 1243-1247, 1998
12. Vareesangthip K, Tong P, Wilkinson R, Thomas TH: Insulin resistance in adult polycystic kidney disease. Kidney Int 52: 503-508, 1997
13. Kato Y, Hayashi M, Ohno Y, Suzawa T, Sasaki T, Saruta T: Mild renal dysfunction is associated with insulin resistance in chronic glomerulonephritis. Clin Nephrol 54: 366-373, 2000
14. Chen J, Muntner P, Hamm LL, Fonseca V, Batuman V, Whelton PK, He J: Insulin resistance and risk of chronic kidney disease in nondiabetic US adults. J Am Soc Nephrol 14: 469-477, 2003
15. Shinohara K, Shoji T, Emoto M, Tahara H, Koyama H, Ishimura E, Miki T, Tabata T, Nishizawa Y: Insulin resistance as an independent predictor of cardiovascular mortality in patients with end-stage renal disease. J Am Soc Nephrol 13: 1894-1900, 2002
16. Goldstein BJ, Scalia R: Adiponectin: A novel adipokine linking adipocytes and vascular function. J Clin Endocrinol Metab 89: 2563-8256, 2004
17. Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y: Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20: 1595-1599, 2000
18. Pischon T, Girman CJ, Hotamisligil GS, Rifai N, Hu FB, Rimm EB: Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 291: 1730-1737, 2004
19. Zoccali C, Mallamaci F, Tripepi G, Benedetto FA, Cutrupi S, Parlongo S, Malatino LS, Bonanno G, Seminara G, Rapisarda F, Fatuzzo P, Buemi M, Nicocia G, Tanaka S, Ouchi N, Kihara S, Funahashi T, Matsuzawa Y: Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. J Am Soc Nephrol 13: 134-141, 2002
20. Kronenberg F, Kuen E, Ritz E, Konig P, Kraatz G, Lhotta K, Mann JF, Muller GA, Neyer U, Riegel W, Riegler P, Schwenger V, von Eckardstein A: Apolipoprotein A-IV serum concentrations are elevated in patients with mild and moderate renal failure. J Am Soc Nephrol 13: 461-469, 2002
21. Gaspari F, Perico N, Matalone M, Signorini O, Azzollini N, Mister M, Remuzzi G: Precision of plasma clearance of iohexol for estimation of GFR in patients with renal disease. J Am Soc Nephrol 9: 310-313, 1998
22. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985
23. Hanley AJ, Williams K, Stern MP, Haffner SM: Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: The San Antonio Heart Study. Diabetes Care 25: 1177-1184, 2002
24. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, Monauni T, Muggeo M: Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: Studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 23: 57-63, 2000
25. Reilly MP, Rader DJ: The metabolic syndrome: More than the sum of its parts? Circulation 108: 1546-1551, 2003
26. Body mass index and cardiovascular disease in the Asia-Pacific Region: An overview of 33 cohorts involving 310 000 participants. Int J Epidemiol 33: 751-758, 2004
27. Thomas GN, Chook P, Qiao M, Huang XS, Leong HC, Celermajer DS, Woo KS: Deleterious impact of "high normal" glucose levels and other metabolic syndrome components on arterial endothelial function and intima-media thickness in apparently healthy Chinese subjects: The CATHAY study. Arterioscler Thromb Vasc Biol 24: 739-743, 2004
28. Fruchart JC, Nierman MC, Stroes ES, Kastelein JJ, Duriez P: New risk factors for atherosclerosis and patient risk assessment. Circulation 109[Suppl 1]: III15-III19, 2004
29. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, McCullough PA, Kasiske BL, Kelepouris E, Klag MJ, Parfrey P, Pfeffer M, Raij L, Spinosa DJ, Wilson PW; American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention: Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 108: 2154-2169, 2003
30. Opie LH, Schall R: Old antihypertensives and new diabetes. J Hypertens 22: 1453-1458, 2004
31. Stenvinkel P, Ottosson-Seeberger A, Alvestrand A: Renal hemodynamics and sodium handling in moderate renal insufficiency: The role of insulin resistance and dyslipidemia. J Am Soc Nephrol 5: 1751-1760, 1995
32. Zoccali C, Mallamaci F, Panuccio V, Tripepi G, Cutrupi S, Parlongo S, Catalano F, Tanaka S, Ouchi N, Kihara S, Funahashi T, Matsuzawa Y: Adiponectin is markedly increased in patients with nephrotic syndrome and is related to metabolic risk factors. Kidney Int Suppl 84: S98-S102, 2003
33. Battezzati A, Caumo A, Martino F, Sereni LP, Coppa J, Romito R, Ammatuna M, Regalia E, Matthews DE, Mazzaferro V, Luzi L: Nonhepatic glucose production in humans. Am J Physiol Endocrinol Metab 286: E129-E135, 2004
34. Mann JFE, Gerstein HC, Dulau-Florea I, Lonn E: Cardiovascular risk in patients with mild renal insufficiency. Kidney Int 63[Suppl 84]: S192-S196, 2003
35. Schmid M, Meyer S, Wegner R, Ritz E: Increased genetic risk of hypertension in glomerulonephritis? Hypertension 8: 573-577, 1990
36. Stenvinkel P, Marchlewska A, Pecoits-Filho R, Heimburger O, Zhang Z, Hoff C, Holmes C, Axelsson J, Arvidsson S, Schalling M, Barany P, Lindholm B, Nordfors L: Adiponectin in renal disease: Relationship to phenotype and genetic variation in the gene encoding adiponectin. Kidney Int 65: 274-281, 2004
37. Tan KCB, Xu A, Chow WS, Lam MCW, Ai VHG, Tam SCF, Lam KSL: Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation. J Clin Endocrinol Metab 89: 765-769, 2004