Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration

Journal of Neuroscience

Volumn 31, Issue 45, 2011, Pages 16269-16278

  Furrer, Stephanie A ^a   Mohanachandran, Mathini S ^a   Waldherr, Sarah M ^a   Chang, Christopher ^a   Damian, Vincent A ^a   Sopher, Bryce L ^a   Garden, Gwenn A ^a   la Spada, Albert R ^a,b,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c RADY CHILDREN'S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 7; COMPLEMENTARY DNA; POLYGLUTAMINE; PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BERGMANN GLIA LAYER; BRAIN NERVE CELL; CEREBELLUM DEGENERATION; CONTROLLED STUDY; GENE; GLIA; INFERIOR OLIVE; MOUSE; MUTANT; NERVE CELL DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRP GENE; PURKINJE CELL; SCA7 GENE; SPINOCEREBELLAR DEGENERATION; TRANSLATION INITIATION;

ANALYSIS OF VARIANCE; ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MUTATION; NERVE TISSUE PROTEINS; NEUROGLIA; NEURONS; PEPTIDES; PHENOTYPE; PRIONS; RNA, MESSENGER; ROTAROD PERFORMANCE TEST; SPINOCEREBELLAR ATAXIAS;

EID: 80755181230     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4000-11.2011     Document Type: Article

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